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Dietary supplement

Advanced Immune Support Ingredients & Drug Interactions

by Human N

Advanced Immune Support label
See full label image
Tablet Or Pill Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Advanced Immune Support against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Advanced Immune Support is a dietary supplement by Human N with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart health, immune support.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Wellmune. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Advanced Immune Support by Human N

Ask about any prescription or over-the-counter medication and we check it for interactions with Advanced Immune Support by Human N — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Advanced Immune Support by Human N

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains one active ingredient: Wellmune, a beta-glucan derived from baker's yeast. Beta-glucans are a type of soluble fiber that interact with your immune system and may help manage cholesterol and heart health.

The remaining ingredients — mannitol, xylitol, natural flavor, citric acid, plant-based magnesium stearate, monk fruit extract, silica, and natural color — are inactive ingredients that give the tablet its form and taste.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Beta-glucans's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: helps maintain a strong immune system.
  • We looked for evidence on: Exercise-induced respiratory infections, Lower respiratory tract infections, Upper respiratory tract infection (URTI), Critical illness (trauma), Wound healing, immune function — and 2 related terms.
  • The closest evidence on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI) (Natural Medicines).
  • Also on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced respiratory infections, Lower respiratory tract infections, Wound healing, Critical illness (trauma).

According to our data, Wellmune beta-glucans are likely effective for managing dyslipidemia (high cholesterol) and reducing coronary heart disease risk. Evidence supports their use for these cardiovascular goals.

We don't hold effectiveness ratings for other uses this product might be marketed for, so if you're taking it for immune support specifically, that evidence isn't in our files.

The evidence, ingredient by ingredient Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food sources are generally well tolerated by most people. However, concentrated supplements like this one lack robust safety data, so use caution — they're not as well studied as food amounts.

The most common side effects reported in trials are topical (skin reactions and contact dermatitis), which are uncommon and typically mild and self-limiting. One rare case in a high-dose pediatric trial saw temporary liver enzyme elevation.

There isn't enough safety data on supplement doses during breastfeeding, so talk with your pharmacist or doctor if you're nursing.

Side effects, ingredient by ingredient Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your blood pressure medications (antihypertensive drugs) and any immunosuppressant medications before taking this product. Beta-glucans may lower blood pressure further and could interfere with drugs meant to suppress immune function.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you have high cholesterol or heart disease risk and want an evidence-backed supplement, Wellmune has solid data behind it. If you take blood pressure medication or any drug that suppresses your immune system, this isn't a simple add-on — you'll need to check your specific medications first.

Talk to your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Advanced Immune Support, straight from the product label.

Brand Human N
Net contents 60 Fast-Melting Tablet(s)
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 248597
Product type Fiber And Other Nutrients
Supplement form Tablet Or Pill
Dietary claims / uses Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Advanced Immune Support by Human N, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
30
IngredientAmount% DV
Wellmune250 mg--

Other ingredients: Mannitol, Xylitol, Natural flavor, Natural color, Citric Acid, Plant-based Magnesium Stearate, Monk Fruit extract, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Helps maintain a strong immune system Promotes immune health

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Wellmune is a registered trademark of Kerry Group

Copyright 2019 Human Power of N. All rights reserved.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Advanced Immune Support by Human N label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Advanced Immune Support label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Advanced Immune Support by Human N

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Wellmune

Interacts with
293 drugs
250 mg per serving Form: Saccharomyces cerevisiae

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly low...

Wellmune monograph & interactions

Other (inactive) ingredients: Mannitol, Xylitol, Natural flavor, Natural color, Citric Acid, Plant-based Magnesium Stearate, Monk Fruit extract, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Advanced Immune Support by Human N Drug Interactions

Want to check YOUR meds against Advanced Immune Support?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Wellmune 293

Individual Drug Interactions

The ingredients in Advanced Immune Support interact with 293 drugs. Click any drug to see the details.

1 of the 1 ingredient in Advanced Immune Support interact with drugs. Each result below shows which ingredient is responsible. Wellmune

Each ingredient & the kinds of drugs it affects

For each ingredient in Advanced Immune Support with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wellmune2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
Wellmune full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Advanced Immune Support, from the product label.

Human N

See all Human N products
Name
Human Power of N
Street Address
1122 S Capital of Texas Hwy Suite 300
City
Austin
State
TX
ZipCode
78746
Pharmacist Counseling Corner

Advanced Immune Support by Human N: Common Questions

Does Advanced Immune Support by Human N interact with any medications?
Yes. Based on its ingredients, Advanced Immune Support has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Advanced Immune Support contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my immune system?
Our data shows Wellmune beta-glucans are likely effective for managing cholesterol and heart disease — those are the supported uses. We don't hold evidence data for general immune support, so we can't confirm that claim.
Is this safe to take every day?
Beta-glucans from food are well tolerated, but concentrated supplements like this one lack long-term safety data. Use caution and talk with your pharmacist about your personal health situation before committing to daily use.
What are the side effects?
Oral beta-glucans seem well tolerated overall. Skin reactions and contact dermatitis have been reported with topical forms, but those are uncommon and usually mild and self-resolving.
Can I take this while pregnant or breastfeeding?
There isn't enough research on supplement doses during pregnancy or breastfeeding. Talk with your doctor or pharmacist — they can weigh the benefit against the unknowns for your situation.
What is Wellmune?
Wellmune is a beta-glucan, a type of fiber extracted from baker's yeast. It's been studied for its effects on cholesterol, heart health, and immune response.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Advanced Immune Support is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Advanced Immune Support label
Go deeper

The Full Monographs Behind Advanced Immune Support’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beta-glucans

Interacts with 293 drugs

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...

Read the full Beta-glucans monograph →
Sources

Sources & How We Checked

Advanced Immune Support's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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