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Dietary supplement

Agaricus Blazei 400 mg Ingredients & Drug Interactions

by Mushroom Science

Agaricus Blazei 400 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Agaricus Blazei 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Agaricus Blazei 400 mg is a dietary supplement by Mushroom Science with 1 active ingredient. Its ingredients are commonly taken for immune support, general wellness and antioxidant, adjunct interest during cancer care.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Agaricus blazei (braziliensis) fruit body extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Agaricus Blazei 400 mg by Mushroom Science

Ask about any prescription or over-the-counter medication and we check it for interactions with Agaricus Blazei 400 mg by Mushroom Science — and tell you which ingredient is responsible.

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Computed from our clinical databases

HelloPharmacist Scorecard of Agaricus Blazei 400 mg by Mushroom Science

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.
Known Interaction Concern
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Agaricus Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 23, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Agaricus Blazei 400 mg, straight from the product label.

Brand Mushroom Science
Barcode (UPC) 669214868914
Net contents 90 Vegetarian Capsules
Market status Off market
Date entered into DSLD Dec 23, 2011
DSLD ID 3073
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Agaricus Blazei 400 mg by Mushroom Science, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
45
UPC/BARCODE
669214868914
IngredientAmount% DV
Agaricus blazei (braziliensis) fruit body extract800 mg--

Other ingredients: Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Agaricus blazei (braziliensis) The newest medicinal mushroom from the rain forests of Brazil, Agaricus blazei (braziliensis) contains the highest levels of beta glucan yet found in a medicinal mushroom. At 45% beta glucan (polysaccharide), this extract represents the highest potency available in an Agaricus blazei (braziliensis) supplement.

Nature's most powerful beta 1-6 glucan

Brand IP Statement(s)

Potency Guaranteed MushroomScience extracts are among the most potent mushroom supplements in the world.

General Statements

Each product is manufactured to the exacting quality standards identified in the supporting scientific research. Our exclusive hot water extraction process guarantees the levels of the active compounds these mushrooms are famous for.

Wood grown mushrooms are known to produce the richest, most potent full spectrum extracts available, and are preferred by herbalist and doctors the world over.

Medicinal mushroom extracts

400 mg each

Formulation

All-Natural Wood Grown Mushrooms Our mushrooms are cultivated exclusively on wood, without the use of chemicals, just the way nature intended.

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Adults, take 1-4 capsules, twice daily, a.m. and p.m. on an empty stomach.

Warnings: Keep out of reach of children.

Precautions

If pregnant or breast feeding, consult a health professional before using this product.

Do not use if hypersensitive to mushrooms.

Do not use if safety seal around top of bottle is missing or broken.

Storage

Store at room temperature.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Agaricus Blazei 400 mg by Mushroom Science label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Agaricus Blazei 400 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Agaricus Blazei 400 mg by Mushroom Science

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Agaricus blazei (braziliensis) fruit body extract

Interacts with
86 drugs
800 mg per serving Form: Beta Glucan

Agaricus mushroom (often Agaricus blazei/subrufescens) is a culinary and medicinal mushroom studied mostly for possible immune and antioxidant effects...

Agaricus blazei (braziliensis) fruit body extract monograph & interactions

Other (inactive) ingredients: Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Agaricus Blazei 400 mg by Mushroom Science Drug Interactions

Agaricus Blazei 400 mg contains a single active ingredient, and it has known interactions with 86 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Agaricus Blazei 400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Agaricus blazei (braziliensis) fruit body extract 86

Individual Drug Interactions

The ingredients in Agaricus Blazei 400 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Agaricus Blazei 400 mg interact with drugs. Each result below shows which ingredient is responsible. Agaricus blazei (braziliensis) fruit body extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Agaricus Blazei 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Agaricus blazei (braziliensis) fruit body extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking agaricus mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
In one clinical study in patients with type 2 diabetes who are stabilized on conventional oral hypoglycemic agents, 3 of 29 patients taking an agaricus mushroom extract 500 mg three times daily for 12 weeks reported hypoglycemia, compared to one of 29 patients in the placebo group.

Likelihood Possible Evidence D
Agaricus blazei (braziliensis) fruit body extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Agaricus Blazei 400 mg, from the product label.

Mushroom Science

See all Mushroom Science products
Name
MushroomScience
Street Address
P.O. Box 50398
City
Eugene
State
OR
ZipCode
97405
Phone Number
1-888-283-6583
Web Address
www.mushroomscience.com
Pharmacist Counseling Corner

Agaricus Blazei 400 mg by Mushroom Science: Common Questions

Does Agaricus Blazei 400 mg by Mushroom Science interact with any medications?
Yes. Based on its ingredients, Agaricus Blazei 400 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Agaricus Blazei 400 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Agaricus Blazei 400 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Agaricus Blazei 400 mg label
Go deeper

The Full Monographs Behind Agaricus Blazei 400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Agaricus Mushroom

Interacts with 86 drugs

Agaricus mushroom (often Agaricus blazei/subrufescens) is a culinary and medicinal mushroom studied mostly for possible immune and antioxidant effects. The human evidence is limited and not...

Read the full Agaricus Mushroom monograph →
Sources

Sources & How We Checked

Agaricus Blazei 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Agaricus Mushroom 5 references
  1. Hsu CH, Liao YL, Lin SC, et al. The mushroom Agaricus Blazei Murill in combination with metformin and gliclazide improves insulin resistance in type 2 diabetes: a randomized, double-blinded, and placebo-controlled clinical trial. J Altern Complement Med 2
  2. Mukai H, Watanabe T, Ando M, Katsumata N. An alternative medicine, Agaricus blazei, may have induced severe hepatic dysfunction in cancer patients. Jpn J Clin Oncol 2006;36:808-10. PubMed
  3. Ohno S, Sumiyoshi Y, Hashine K, et al. Phase I clinical study of the dietary supplement, Agaricus blazei Murill, in cancer patients in remission. Evid Based Complement Alternat Med 2011, doi 10.1155/2011/192381.
  4. Suehiro M, Katoh N, Kishimoto S. Chelitis due to Agaricus blazei Murill mushroom extract. Contact Dermatitis 2007;56(5):293-4.
  5. Iwai N, Okuda T, Sawada R, et al. Interstitial lung disease associated with Agaricus blazei Murill in a patient with pancreatic ductal adenocarcinoma receiving gemcitabine-based therapy. Case Rep Gastroenterol 2022;16(1):229-234.

See these in context on the Agaricus Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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