Major interaction on record — check this product against your medications before combining. Based on 5 of 11 ingredients. Check your meds →
Dietary supplement

Aloe 10,000 & Probiotics Ingredients & Drug Interactions

by NOW

Aloe 10,000 & Probiotics label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Aloe 10,000 & Probiotics against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Aloe 10,000 & Probiotics is a dietary supplement by NOW with 11 active ingredients. Its ingredients are commonly taken for minor burns and skin irritation, wound healing, constipation.Based on those ingredients, 641 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are organic Aloe Vera, Bifidobacterium longum BI-05, Bifidobacterium breve (Bb-03). Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Aloe 10,000 & Probiotics by NOW

Ask about any prescription or over-the-counter medication and we check it for interactions with Aloe 10,000 & Probiotics by NOW — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Aloe 10,000 & Probiotics by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 11 active ingredients.
  • “Blend of 10 Strains of Probiotic Bacteria” is a proprietary blend — the label gives one combined amount (40 mg) without saying how much of each component you get.

This product contains 11 ingredients: 10 strains of live probiotic bacteria and organic aloe vera. The probiotics include Bifidobacterium longum, Bifidobacterium breve, Bifidobacterium animalis lactis, Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus rhamnosus, Lactobacillus casei, Lactobacillus salivarius, and Streptococcus thermophilus.

These live organisms are meant to support your gut flora. The aloe vera is the plant-based second active ingredient.

The capsules also contain inactive ingredients—microcrystalline cellulose (a binder), hypromellose (a capsule material), fructooligosaccharides (a prebiotic fiber), stearic acid, and silicon dioxide—which help hold the product together and deliver it.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Digestive health and probiotic support.
  • We looked for evidence on: Antibiotic-associated diarrhea, Constipation, Diarrhea, Colic, Gut microbiome balance, Digestive comfort — and 1 related terms.
  • The strongest evidence on file: Aloe is rated "Possibly Effective" for Constipation (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea.
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Constipation, Radiation-induced diarrhea, Rotaviral diarrhea, Travelers' diarrhea, and more.

The evidence for these probiotics is mixed and limited. Lactobacillus acidophilus shows possibly effective ratings for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.

The other probiotic strains mostly have insufficient evidence to rate them, though Bifidobacterium breve is rated possibly ineffective for age-related cognitive decline and sepsis. Aloe vera fares better: it's rated possibly effective for acne, obesity, diabetes, psoriasis, burns, and constipation.

That said, the strength of evidence behind both the probiotics and aloe for most conditions is not established in our data, so talk with your pharmacist or doctor about whether this product is right for what you're trying to address.

The evidence, ingredient by ingredient Aloe Streptococcus Thermophilus Bifidobacterium Longum Bifidobacterium Breve Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The probiotics in this product are generally well tolerated in healthy people, but they need caution in anyone with a weakened immune system or serious illness—there have been rare cases of infection (bacteremia and sepsis) in critically ill patients, preterm infants, and people with central lines or catheters. Bifidobacterium longum is rated possibly safe in pregnancy and lactation, but the other probiotics have limited safety data, so check with your doctor before use during pregnancy or breastfeeding.

Aloe is a different story: oral aloe latex (which this product likely contains) can cause abdominal pain, cramps, and diarrhea, and long-term use may lead to potassium loss and electrolyte imbalances. You should avoid taking aloe by mouth during pregnancy because it may stimulate the uterus and act as a strong laxative, and avoid it while breastfeeding due to limited safety data and its laxative effects.

Probiotics from food sources are generally considered more acceptable during pregnancy and breastfeeding, but talk with your provider first.

Side effects, ingredient by ingredient Aloe Streptococcus Thermophilus Bifidobacterium Longum Bifidobacterium Breve Lactobacillus Acidophilus

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Aloe, Lactobacillus Acidophilus, Bifidobacterium Breve, Bifidobacterium Longum.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications.
  • For scale: 641 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your pharmacist if you take digoxin (Lanoxin)—that's a Major interaction with aloe. Also flag anticoagulants or blood thinners like warfarin, diabetes medications, diuretics, stimulant laxatives, or antibiotics—all of these have Moderate interactions.

If you take any CYP1A2 substrate drugs (ask your pharmacist for the list), aloe may affect them as well, though that's a Minor concern.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

If you have a healthy immune system and no serious illness, you may consider this for digestive support or the possible benefits aloe offers. However, be careful if you take digoxin, blood thinners, diabetes medications, diuretics, or antibiotics—your pharmacist needs to know.

Pregnant or breastfeeding women, people who are severely ill or immunocompromised, and anyone with a central line should talk to their doctor before taking it. Check your exact medications with the tool on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Aloe 10,000 & Probiotics, straight from the product label.

Brand NOW
Barcode (UPC) 733739030290
Net contents 60 Veg Capsule(s)
Market status On market
Date entered into DSLD May 23, 2024
DSLD ID 313559
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Aloe 10,000 & Probiotics by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veg Capsule(s)
Maximum serving Sizes:
1 Veg Capsule(s)
Servings per container
60
UPC/BARCODE
733739030290
IngredientAmount% DV
Streptococcus thermophilus (St-21)0 NP--
Bifidobacterium longum BI-050 NP--
Bifidobacterium breve (Bb-03)0 NP--
Lactobacillus paracasei Lpc-370 NP--
Lactobacillus plantarum (Lp-115)0 NP--
organic Aloe Vera50 mg--
Blend of 10 Strains of Probiotic Bacteria40 mg--
Lactobacillus acidophilus La-140 NP--
Lactobacillus rhamnosus (Lr-32)0 NP--
Lactobacillus casei (Lc-11)0 NP--
Bifidobacterium animalis lactis Bl-040 NP--
Lactobacillus salivarius (Ls-33)0 NP--

Other ingredients: Microcrystalline Cellulose, Hypromellose, Fructooligosaccharides, Stearic Acid, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 1 capsule twice daily.

Storage

Keep refrigerated to maintain potency.

Formula

Aloe Vera offers a variety of nutrients, including vitamins, minerals, enzymes and amino acids. Aloe Vera’s constituent mucopolysaccharides, also known as glycosaminoglycans (GAGs), are thought to be its active component. Scientific studies have indicated that Aloe can help to support the body’s own healing processes. A 10-Strain Probiotic Blend has been included to complement Aloe’s role in the support of a healthy digestive system.

10,000 mg Aloe vera equivalency 10-strain (5 billion) Probiotic blend

Triangle K (Kosher)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: For adults only.

Consult physician if pregnant/nursing, taking medication (especially immune-suppressing and anti-diabetes drugs), or have a medical condition (especially if immune system is compromised or if diabetic or hypoglycemic).

Keep out of reach of children.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

General Statements

This bottle is made from 100% PCR (post-consumer recycled) resin.

Digestive Family owned since 1968.

Formulation

Supports digestive health

Non-GMO

Vegetarian/Vegan

Made and quality tested in the USA with globally sourced ingredients.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients.

Natural color variation may occur in this product.

The probiotic strains in this product have been identity-verified using DNA-fingerprinting technology.

Seals/Symbols

Triangle K (Kosher)

Strain Verified

GMP Quality Assured

FDA Statement of Identity

A Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Aloe 10,000 & Probiotics by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Aloe 10,000 & Probiotics label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Aloe 10,000 & Probiotics by NOW

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Veg Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Organic Aloe Vera

Interacts with
461 drugs
50 mg per serving

Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a str...

Organic Aloe Vera monograph & interactions

Blend of 10 Strains of Probiotic Bacteria

40 mg per serving

Other (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, Fructooligosaccharides, Stearic Acid, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Aloe 10,000 & Probiotics by NOW Drug Interactions

Want to check YOUR meds against Aloe 10,000 & Probiotics?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
641Drugs
1 Major 485 Moderate 155 Minor

Ingredients driving the most interactions

organic Aloe Vera 461
Bifidobacterium longum BI-05 182
Bifidobacterium breve (Bb-03) 182
Lactobacillus acidophilus La-14 182

Individual Drug Interactions

The ingredients in Aloe 10,000 & Probiotics interact with 641 drugs. Click any drug to see the details.

4 of the 11 ingredients in Aloe 10,000 & Probiotics interact with drugs. Each result below shows which ingredient is responsible. organic Aloe Vera Bifidobacterium longum BI-05 Bifidobacterium breve (Bb-03) Lactobacillus acidophilus La-14

Each ingredient & the kinds of drugs it affects

For each ingredient in Aloe 10,000 & Probiotics with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Aloe Vera7 drug types · 461 drugs

Digoxin (Lanoxin)

Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Overuse of aloe latex can increase the risk of adverse effects from cardiac glycoside drugs, such as digoxin, due to potassium depletion. Overuse of aloe, along with cardiac glycoside drugs, can increase the risk of toxicity.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aloe gel can inhibit platelet aggregation. This inhibition was greater than that seen with celecoxib, but less than that seen with aspirin.

Likelihood Possible Evidence D
Antidiabetes Drugs

Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Preliminary clinical research suggests aloe gel might lower blood glucose levels and have additive effects when used with antidiabetes drugs. Monitor blood glucose levels closely.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of aloe latex might compound diuretic-induced potassium loss, increasing the risk of hypokalemia.

Likelihood Possible Evidence D
Stimulant Laxatives

Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Due to cathartic laxative effects of aloe latex, concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, aloe latex might increase the risk of bleeding when taken with warfarin.
Aloe latex has stimulant laxative effects. In some people aloe latex can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of aloe vera.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that aloe extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
organic Aloe Vera full monograph & interactions

Bifidobacterium longum BI-051 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium longum BI-05 full monograph & interactions

Bifidobacterium breve (Bb-03)1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B. breve.
Since B. breve preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. breve preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium breve (Bb-03) full monograph & interactions

Lactobacillus acidophilus La-141 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus La-14 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Aloe 10,000 & Probiotics, from the product label.

NOW

See all NOW products
Name
NOW FOODS
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowfoods.com
Pharmacist Counseling Corner

Aloe 10,000 & Probiotics by NOW: Common Questions

Does Aloe 10,000 & Probiotics by NOW interact with any medications?
Yes. Based on its ingredients, Aloe 10,000 & Probiotics has a known interaction with 641 medications, including 1 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Aloe 10,000 & Probiotics contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take this if I'm pregnant?
The safety data here are limited. Aloe should be avoided by mouth during pregnancy because the latex may stimulate the uterus and work as a strong laxative. Bifidobacterium longum is rated possibly safe in pregnancy, but the other probiotics don't have enough data. Talk with your doctor or pharmacist before taking this product if you're pregnant or planning to be.
Can I take this while I'm on antibiotics?
Not at the same time. Three of the probiotics here—Bifidobacterium longum, Bifidobacterium breve, and Lactobacillus acidophilus—are live organisms that antibiotics may kill. Your doctor may recommend spacing them several hours apart so the antibiotic doesn't wipe out the probiotic. Ask your pharmacist for the best timing.
What side effects should I watch for?
With the probiotics, you might get abdominal discomfort, bloating, flatulence, or diarrhea—these are usually rare and mild. With aloe, especially if taken in high doses or long-term, you can get cramping, diarrhea, and potassium loss. Serious side effects with aloe are rare but include muscle weakness and irregular heartbeats from low potassium.
Will this really help my IBS or constipation?
Lactobacillus acidophilus in this formula is rated possibly effective for IBS and antibiotic-associated diarrhea, and aloe is rated possibly effective for constipation. That means the evidence suggests they may help, but it's not definitive. Results vary person to person, so give it time and talk with your doctor if you don't see improvement.
Is this safe if my immune system is weak?
No, you should be careful. These are live probiotics, and there have been rare cases of infection in people with weakened immune systems, serious illness, or central lines. If you're immunocompromised or critically ill, ask your doctor before taking this product.
Can I breastfeed while taking this?
There isn't enough safety data to say for sure. Aloe should be avoided while breastfeeding because of its laxative effects and limited safety data. Probiotics from food are generally considered acceptable, but you should check with your doctor or pharmacist before taking a supplement like this while nursing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Aloe 10,000 & Probiotics is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Aloe 10,000 & Probiotics label
Go deeper

The Full Monographs Behind Aloe 10,000 & Probiotics’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Aloe

Interacts with 461 drugs

Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a strong laxative that can cause cramping and...

Read the full Aloe monograph → Herb & supplement monograph

Streptococcus Thermophilus

Streptococcus thermophilus is a friendly bacterium used as a probiotic, often combined with other strains in yogurt and supplements. It is generally well tolerated in healthy people and may...

Read the full Streptococcus Thermophilus monograph → Herb & supplement monograph

Bifidobacterium Longum

Interacts with 182 drugs

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...

Read the full Bifidobacterium Longum monograph → Herb & supplement monograph

Bifidobacterium Breve

Interacts with 182 drugs

Bifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies suggest possible benefits for certain d...

Read the full Bifidobacterium Breve monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph →
Sources

Sources & How We Checked

Aloe 10,000 & Probiotics's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 107 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Streptococcus Thermophilus 21 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
  6. Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
  7. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  8. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
  9. De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
  10. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
  11. Dolatkhah N, Hajifaraji M, Abbasalizadeh F, Aghamohammadzadeh N, Mehrabi Y, Abbasi MM. Is there a value for probiotic supplements in gestational diabetes mellitus? A randomized clinical trial. J Health Popul Nutr. 2015;33:25. PubMed
  12. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  13. Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
  14. Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
  15. Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
  16. Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
  17. Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
  18. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  19. Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
  20. Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
  21. Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed

See these in context on the Streptococcus Thermophilus monograph →

Bifidobacterium Longum 21 references
  1. Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
  2. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
  5. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  6. Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
  7. Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
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Bifidobacterium Breve 9 references
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Aloe 41 references
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Lactobacillus Acidophilus 15 references
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  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
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  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

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