Aloe Gold Tablets 300 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Aloe Gold Tablets 300 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Aloe Gold Tablets 300 mg is a dietary supplement by Higher Nature with 1 active ingredient. Its ingredients are commonly taken for minor burns and skin irritation, wound healing, constipation.Based on those ingredients, 461 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are whole leaf Aloe Vera (Aloe barbadensis Miller) juice concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Aloe Gold Tablets 300 mg by Higher Nature
Ask about any prescription or over-the-counter medication and we check it for interactions with Aloe Gold Tablets 300 mg by Higher Nature — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Aloe Gold Tablets 300 mg by Higher Nature
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: whole leaf aloe vera juice concentrate at 300 mg per tablet. The ingredient includes both the latex (the yellow substance under the leaf skin) and the inner gel, both of which have biological activity.
The remaining ingredients are inactive — they're the tablet binders, fillers, and capsule material that hold everything together.
Does it work?
Moderate evidence
The evidence suggests aloe may be possibly effective for acne, obesity, diabetes, psoriasis, burns, and constipation. That means preliminary research is encouraging, but we don't yet have enough high-quality data to call it proven.
If you're considering it for one of these uses, talk to your pharmacist or doctor about whether the current evidence fits your situation.
How safe is it?
Well-documented data
Topical aloe gel is generally well tolerated in typical doses, but oral aloe — especially the latex — carries more risk, particularly at high doses or with long-term use. The most common side effect when taken by mouth is abdominal pain, cramps, and diarrhea.
Long-term use can lead to potassium depletion, muscle weakness, and heart rhythm problems. Do not take this product if you're pregnant or breastfeeding — the latex can stimulate the uterus and act as a strong laxative, and safety data during breastfeeding is limited.
Meds to double-check
Major interaction found
Before taking this product, double-check if you're on digoxin or other heart medications (Major interaction), blood thinners like warfarin, antiplatelet drugs, diabetes medications, water pills (diuretics), or other stimulant laxatives (all Moderate). Also mention any drugs your liver metabolizes via the CYP1A2 pathway (Minor interaction).
If you're unsure, run your medications through the checker on this page.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.
Aloe tablets may help with a few conditions, but they interact with heart and blood-thinning medications, diabetes drugs, and water pills — so check with your pharmacist first if you take any prescriptions. Avoid it entirely if you're pregnant or nursing.
For most people without those contraindications, typical short-term use is usually fine, but watch for cramping and diarrhea.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 29, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Aloe Gold Tablets 300 mg, straight from the product label.
| Brand | Higher Nature |
|---|---|
| Barcode (UPC) | 5031013105869 |
| Net contents | 30 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Dec 29, 2014 |
| DSLD ID | 40869 |
| Product type | Botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other |
| Intended target group(s) | Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), No Allergies, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Aloe Gold Tablets 300 mg by Higher Nature, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| whole leaf Aloe Vera (Aloe barbadensis Miller) juice concentrate | 300 mg | -- |
Other ingredients: Aloe vera (Aloe barbadensis Miller) whole leaf and inner gel concentrate, Calcium Carbonate, Magnesium Carbonate, Magnesium Citrate, Calcium Citrate, Magnesium Stearate, Stearic Acid, Hydroxypropyl Methylcellulose, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
DOES NOT CONTAIN: sugar, salt, starch, soya, wheat, gluten, yeast, lactose, dairy products, artificial preservatives, colours or flavourings.
Suitable for vegetarians and vegans.
VEGETARIAN
Aloe Gold Tablets contain organically grown Aloe vera.
General Statements
This product is not tested on animals.
ALOE GOLD is produced for HIGHER NATURE by Aloe Life International (www.aloelife.com), a Member of the International Aloe Science Council.
Charitable organisations policy: supplements regularly donated
Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.
Aloe vera helps maintain regular bowel movement, healthy digestion, skin, immune system, menstruation and energy levels. It’s antioxidant properties may help protect against excess free radicals, which contribute to premature ageing. Aloe naturally contains up to 200 nutrients, including polysaccharides, vitamins, minerals, amino acids and enzymes, plus natural cleansing compounds.
This bottle has a UV filter.
Formula
Hypo-allergenic formula.
Aloe Gold Tablets contain organically grown Aloe vera.
FDA Statement of Identity
FOOD SUPPLEMENT
General
AGT030 102 AGT-358-01
Suggested/Recommended/Usage/Directions
DIRECTIONS: Adults and children over 12 years, take 1-3 tablets a day, half an hour before or 2 hours after meals. Children aged 4-12 years take 1/2 to 1 tablet a day. Reduce intake if diarrhoea occurs.
Precautions
Do not exceed recommended daily intake.
Keep out of reach of children.
Storage
Ensure lid is tight and store in a cool, dry, steam-free environment as damp conditions can affect the product quality.
Seals/Symbols
Jar {Recycle} 1 PET
Lid {Recycle} 5 PP
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Aloe Gold Tablets 300 mg by Higher Nature label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Aloe Gold Tablets 300 mg by Higher Nature
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.
Whole leaf Aloe Vera (Aloe barbadensis Miller) juice concentrate
Interacts with461 drugs
Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a str...
Whole leaf Aloe Vera (Aloe barbadensis Miller) juice concentrate monograph & interactionsOther (inactive) ingredients: Aloe vera (Aloe barbadensis Miller) whole leaf and inner gel concentrate, Calcium Carbonate, Magnesium Carbonate, Magnesium Citrate, Calcium Citrate, Magnesium Stearate, Stearic Acid, Hydroxypropyl Methylcellulose, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Aloe Gold Tablets 300 mg by Higher Nature Drug Interactions
HelloPharmacist Interaction Report
Aloe Gold Tablets by Higher Nature contain aloe latex, which interacts with several important medication types.
The most serious concern is with digoxin (Lanoxin), a heart medication — overuse of aloe can deplete potassium and increase the risk of digoxin toxicity.
Read the full breakdown — every affected drug type, severity by severity
Moderate interactions exist with blood thinners like warfarin (Coumadin) and antiplatelet drugs; aloe may increase bleeding risk. Aloe can also lower blood sugar, so it may have additive effects with diabetes medications — you'll want to monitor your levels closely.
Similarly, aloe's laxative effects can compound potassium loss if you're taking water pills (diuretics), and using it alongside other stimulant laxatives could increase fluid and electrolyte loss.
There's also a minor interaction with certain drugs that your liver processes via the CYP1A2 enzyme — aloe may lower their effectiveness. Altogether, these interactions span 460 individual medications.
Use the medication checker below to verify your specific prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Aloe Gold Tablets 300 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Aloe Gold Tablets 300 mg interact with 461 drugs. Click any drug to see the details.
1 of the 1 ingredient in Aloe Gold Tablets 300 mg interact with drugs. Each result below shows which ingredient is responsible. whole leaf Aloe Vera (Aloe barbadensis Miller) juice concentrate
DigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateDigoxin (lanoxin) Major
Interaction Summary
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Digoxin interactionAbciximabReoPro
How Abciximab interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Acetaminophen, Ibuprofen interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Argatroban interactionArmodafinilNuvigil
How Armodafinil interacts with Aloe Gold Tablets 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice ConcentrateStimulant Laxatives Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Read the full Whole Leaf Aloe Vera (aloe Barbadensis Miller) Juice Concentrate + Armodafinil interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Aloe Gold Tablets 300 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
whole leaf Aloe Vera (Aloe barbadensis Miller) juice concentrate
Digoxin (Lanoxin)
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Overuse of aloe latex can increase the risk of adverse effects from cardiac glycoside drugs, such as digoxin, due to potassium depletion. Overuse of aloe, along with cardiac glycoside drugs, can increase the risk of toxicity.
Anticoagulant/Antiplatelet Drugs
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aloe gel can inhibit platelet aggregation. This inhibition was greater than that seen with celecoxib, but less than that seen with aspirin.
Antidiabetes Drugs
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Preliminary clinical research suggests aloe gel might lower blood glucose levels and have additive effects when used with antidiabetes drugs. Monitor blood glucose levels closely.
Diuretic Drugs
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of aloe latex might compound diuretic-induced potassium loss, increasing the risk of hypokalemia.
Stimulant Laxatives
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Due to cathartic laxative effects of aloe latex, concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.
Warfarin (Coumadin)
Theoretically, aloe latex might increase the risk of bleeding when taken with warfarin.
Aloe latex has stimulant laxative effects. In some people aloe latex can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of aloe vera.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that aloe extract induces CYP1A2 enzymes.
Brand information
Manufacturer and brand details for Aloe Gold Tablets 300 mg, from the product label.
Higher Nature
See all Higher Nature products- Name
- Higher Nature
- City
- Burwash Common
- State
- East Sussex
- ZipCode
- TN19 7LX
- Web Address
- www.highernature.com
Aloe Gold Tablets 300 mg by Higher Nature: Common Questions
Does Aloe Gold Tablets 300 mg by Higher Nature interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take Aloe Gold if I'm on a blood thinner?
Will this help my diabetes?
Is it safe to take aloe tablets long-term?
Can I take this while pregnant or breastfeeding?
What's the difference between the gel and latex in aloe?
What side effects should I watch for?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Aloe Gold Tablets 300 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Aloe Gold Tablets 300 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Aloe Gold Tablets 300 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 41 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Aloe 41 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
- Luyckx VA, Ballantine R, Claeys M, et al. Herbal remedy-associated acute renal failure secondary to Cape aloes. Am J Kidney Dis 2002;39:E13. PubMed
- Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S. Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. J Med Food 2004;7:61-6.
- Williams MS, Burk M, Loprinzi CL, et al. Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity. Int J Radiat Oncol Biol Phys 1996;36:345-9. PubMed
- Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract 1999;49:823-8.
- Bottenberg MM, Wall GC, Harvey RL, Habib S. Oral aloe vera-induced hepatitis. Ann Pharmacother 2007;41:1740-3. PubMed
- Rabe C, Musch A, Schirmacher P, et al. Acute hepatitis induced by an Aloe vera preparation: a case report. World J Gastroenterol 2005;11:303-4. PubMed
- Kanat O, Ozet A, Ataergin S. Aloe vera-induced acute toxic hepatitis in a healthy young man. Eur J Int Med 2006;17:589. PubMed
- Mueller SO, Stopper H. Characterization of the genotoxicity of anthraquinones in mammalian cells. Biochim Biophys Acta 1999;1428:406-14. PubMed
- Schorkhuber M, Richter M, Dutter A, et al. Effect of anthraquinone laxatives on the proliferation and urokinase secretion of normal, premalignant and malignant colonic epithelial cells. Eur J Cancer 1998;34:1091-8. PubMed
- Yang HN, Kim DJ, Kim YM, et al. Aloe-induced toxic hepatitis. J Korean Med Sci 2010;25:492-5. PubMed
- Choonhakarn C, Busaracome P, Sripanidkulchai B, et al. A prospective, randomized clinical trial comparing topical aloe vera with 0.1% triamcinolone acetonide in mild to moderate plaque psoriasis. J.Eur.Acad.Dermatol.Venereol. 2010;24:168-72. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. IV. Mechanism of cathartic effect. (3). Biol Pharm Bull. 1994;17:495-7. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. V. Mechanism of cathartic effect. (4). Biol Pharm Bull. 1994;17:651-3. PubMed
- Nelemans FA. Clinical and toxicological aspects of anthraquinone laxatives. Pharmacology. 1976;14 Suppl 1:73-7. PubMed
- Paulsen E, Korsholm L, Brandrup F. A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. J Eur Acad Dermatol Venereol. 2005;19:326-31.
- Huseini HF, Kianbakht S, Hajiaghaee R, et al. Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Planta Med. 2012;78:311-6
- Ferreira, M., Teixeira, M., Silva, E., and Selores, M. Allergic contact dermatitis to Aloe vera. Contact Dermatitis 2007;57(4):278-279.
- Choonhakarn, C., Busaracome, P., Sripanidkulchai, B., and Sarakarn, P. The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial. Br J Dermatol 2008;158(3):573-577. PubMed
- Baretta, Z., Ghiotto, C., Marino, D., and Jirillo, A. Aloe-induced hypokalemia in a patient with breast cancer during chemotherapy. Ann.Oncol. 2009;20(8):1445-1446. PubMed
- Hunter, D. and Frumkin, A. Adverse reactions to vitamin E and aloe vera preparations after dermabrasion and chemical peel. Cutis 1991;47(3):193-196.
- Alvarez-Perea, A., Garcia, A. P., Hernandez, A. L., de, Barrio M., and Baeza, M. L. Urticaria due to aloe vera: a new sensitizer? Ann.Allergy Asthma Immunol. 2010;105(5):404-405. PubMed
- Hogan, D. J. Widespread dermatitis after topical treatment of chronic leg ulcers and stasis dermatitis. CMAJ. 2-15-1988;138(4):336-338.
- Savchak VI. Acute bullous allergic dermatitis due to local application of aloe leaves. Vestnik Dermatologii i Venerologii 1977;12:44-45.
- Nakamura, T. and Kotajima, S. Contact dermatitis from aloe arborescens. Contact Dermatitis 1984;11(1):51. PubMed
- Shoji, A. Contact dermatitis to Aloe arborescens. Contact Dermatitis 1982;8(3):164-167. PubMed
- Morrow, D. M., Rapaport, M. J., and Strick, R. A. Hypersensitivity to aloe. Arch Dermatol. 1980;116(9):1064-1065. DOI
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of AloeAndongensis Extract, Aloe Andongensis Leaf Juice,aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower E
- Bhalang K, Thunyakitpisal P, Rungsirisatean N. Acemannan, a polysaccharide extracted from Aloe vera, is effective in the treatment of oral aphthous ulceration. J Altern Complement Med 2013;19(5):429-34.
- Hajheydari Z, Saeedi M, Morteza-Semnani K, Soltani A. Effect of Aloe vera topical gel combined with tretinoin in treatment of mild and moderate acne vulgaris: a randomized, double-blind, prospective trial. J Dermatolog Treat 2014;25(2):123-9.
- Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep 2012;2012. PubMed
- Lee J, Lee MS, Nam KW. Acute toxic hepatitis caused by an aloe vera preparation in a young patient: a case report with a literature review. Korean J Gastroenterol 2014;64(1):54-8. PubMed
- Guo X, Mei N. Aloe Vera - A Review of Toxicity and Adverse Clinical Effects. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 2016;34(2):77-96.
- Hoogenboom TCH, Patel N, Cook NA, Williams R, Taylor-Robinson SD, Lim AKP. The effect of Aloe vera juice on liver enzymes and hepatic structure in a healthy population. Integr Med (Encinitas) 2020;19(3):30-4.
- Mushtaq S, Mushtaq Z, Sarfraz J, et al. Comparison of effect of aloe vera gel with aspirin and celecoxib on platelet aggregation. Professional Med J. 2020; 27(5):973-978. DOI
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
- Sabbaghzadegan S, Soltani MH, Kamalinejad M, Bahrami M, Kabir A, Dadmehr M. The effect of a standardized capsule of Aloe vera gel on the quality of life in patients with systolic heart failure: A randomized double-blind placebo-controlled clinical trial.
- Lewis ED, Crowley DC, Guthrie N, Evans M. Healthy adults supplemented with a nutraceutical formulation containing Aloe vera gel, rosemary and Poria cocos enhances the effect of influenza vaccination in a randomized, triple-blind, placebo-controlled trial. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC