Aloe Vera 10,000 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Aloe Vera 10,000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Aloe Vera 10,000 mg is a dietary supplement by Herbal Secrets with 1 active ingredient. Its ingredients are commonly taken for minor burns and skin irritation, wound healing, constipation.Based on those ingredients, 461 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Aloe Vera Inner Leaf Gel Concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Aloe Vera 10,000 mg by Herbal Secrets
Ask about any prescription or over-the-counter medication and we check it for interactions with Aloe Vera 10,000 mg by Herbal Secrets — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Aloe Vera 10,000 mg by Herbal Secrets
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product has one active ingredient: aloe vera inner leaf gel concentrate at 10,000 mg per softgel. The gel comes from the inner part of the aloe leaf and is where the plant's active compounds live.
The softgel also contains two inactive ingredients—beeswax and olive oil—which help with absorption and capsule texture.
Does it work?
Moderate evidence
Aloe vera is possibly effective for acne, obesity, diabetes, psoriasis, burns, and constipation, according to the evidence we have on file. That means the research suggests it may help with these conditions, but more study is needed to be certain.
If you're thinking about using it for one of these reasons, talk with your pharmacist about whether it makes sense for your situation.
How safe is it?
Well-documented data
When taken by mouth, aloe is generally well tolerated at typical doses, but oral aloe latex carries real risks—especially at high doses or over the long haul. You might experience abdominal pain, cramps, or diarrhea.
Long-term overuse can cause serious electrolyte imbalances, muscle weakness, and heart rhythm problems. Avoid aloe by mouth during pregnancy because it may stimulate the uterus and act as a powerful laxative.
Breastfeeding isn't recommended either due to limited safety data and laxative effects. If you're thinking about this product while pregnant or nursing, talk with your doctor or pharmacist first.
Meds to double-check
Major interaction found
Before taking this product, double-check these medication types with your pharmacist: digoxin or other heart medications (Major risk), then blood thinners like warfarin, diabetes drugs, diuretics, and stimulant laxatives (all Moderate risk). Also check any medications that rely on liver processing, like certain antidepressants or cancer drugs (Minor risk).
No interaction data means we haven't documented it—not that none exists.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Aloe vera may help with acne, burns, constipation, and a few other conditions, but it's not a casual supplement—it interacts with major heart and blood-thinning drugs, diabetes medications, and diuretics. If you take any prescription medications, check them against our tool before you start.
Anyone pregnant, breastfeeding, or managing a heart condition should talk with their pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Aloe Vera 10,000 mg, straight from the product label.
| Brand | Herbal Secrets |
|---|---|
| Barcode (UPC) | 810180029254 |
| Net contents | 120 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Mar 22, 2023 |
| DSLD ID | 282801 |
| Product type | Botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Aloe Vera 10,000 mg by Herbal Secrets, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Aloe Vera Inner Leaf Gel Concentrate | 10000 mg | -- |
Other ingredients: Beeswax, Olive Oil
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Herbal Secrets Aloe Vera softgels provides soothing support for healthy digestion and overall vitality while providing nutritional support for digestive tissues. In addition, the rich vitamins and minerals in Aloe Vera supports overall health and well-being by aiding immune system functions.
Rich In Nutrients & Fiber
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, adults take three (3) softgels 2 to 3 times daily, preferably on an empty stomach or as directed by a health care professional.
Precautions
Caution: If you are pregnant, nursing, taking any medication(s) or have any medical condition, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Keep out of reach of children.
Do not use if safety seal is damaged or missing.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
Made in the USA
GMP Good Manufacturing Practice Quality Product
Formulation
100% Natural
Soothes Digestive Track Regulates Intestinal Bacteria Helps Improve Immune Function
Contains No: Artificial preservatives, colors, flavors or sweeteners, sugar, milk, lactose, soy, gluten, wheat, yeast, fish or sodium.
FDA Statement of Identity
Natural Dietary Supplement
Storage
Store in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Aloe Vera 10,000 mg by Herbal Secrets label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Aloe Vera 10,000 mg by Herbal Secrets
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size3 Softgel(s) Dosage formSoftgel Capsule Servings per container120 Amounts shown are per serving.
Aloe Vera Inner Leaf Gel Concentrate
Interacts with461 drugs
Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a str...
Aloe Vera Inner Leaf Gel Concentrate monograph & interactionsOther (inactive) ingredients: Beeswax, Olive Oil. These complete the product’s ingredient list but are not active constituents.
Aloe Vera 10,000 mg by Herbal Secrets Drug Interactions
HelloPharmacist Interaction Report
Aloe Vera 10,000 mg by Herbal Secrets does interact with several medication types, and the most serious concern is digoxin (Lanoxin), a heart medication.
Overuse of aloe can deplete potassium, which raises the risk of toxicity when you're also taking digoxin. If you take this heart drug, you'll want to check with us before starting aloe.
Read the full breakdown — every affected drug type, severity by severity
Aloe can also increase bleeding risk with blood thinners (anticoagulants) and antiplatelet drugs like warfarin — the laxative effects can trigger diarrhea, which amplifies warfarin's potency. It may lower blood sugar when combined with diabetes medications, so you'd need close monitoring.
Diuretics and stimulant laxatives both pose electrolyte-loss risks if paired with aloe, especially potassium depletion. Finally, aloe may weaken the effects of certain medications processed by the liver (CYP1A2 substrates), though this is a minor concern.
Allogther, these interactions span 460 individual medications. Use the medication checker on this page to search your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Aloe Vera 10,000 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Aloe Vera 10,000 mg interact with 461 drugs. Click any drug to see the details.
1 of the 1 ingredient in Aloe Vera 10,000 mg interact with drugs. Each result below shows which ingredient is responsible. Aloe Vera Inner Leaf Gel Concentrate
DigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateDigoxin (lanoxin) Major
Interaction Summary
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Digoxin interactionAbciximabReoPro
How Abciximab interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Acetaminophen, Ibuprofen interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Argatroban interactionArmodafinilNuvigil
How Armodafinil interacts with Aloe Vera 10,000 mg — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Inner Leaf Gel ConcentrateStimulant Laxatives Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Read the full Aloe Vera Inner Leaf Gel Concentrate + Armodafinil interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Aloe Vera 10,000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Aloe Vera Inner Leaf Gel Concentrate
Digoxin (Lanoxin)
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Overuse of aloe latex can increase the risk of adverse effects from cardiac glycoside drugs, such as digoxin, due to potassium depletion. Overuse of aloe, along with cardiac glycoside drugs, can increase the risk of toxicity.
Anticoagulant/Antiplatelet Drugs
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aloe gel can inhibit platelet aggregation. This inhibition was greater than that seen with celecoxib, but less than that seen with aspirin.
Antidiabetes Drugs
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Preliminary clinical research suggests aloe gel might lower blood glucose levels and have additive effects when used with antidiabetes drugs. Monitor blood glucose levels closely.
Diuretic Drugs
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of aloe latex might compound diuretic-induced potassium loss, increasing the risk of hypokalemia.
Stimulant Laxatives
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Due to cathartic laxative effects of aloe latex, concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.
Warfarin (Coumadin)
Theoretically, aloe latex might increase the risk of bleeding when taken with warfarin.
Aloe latex has stimulant laxative effects. In some people aloe latex can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of aloe vera.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that aloe extract induces CYP1A2 enzymes.
Brand information
Manufacturer and brand details for Aloe Vera 10,000 mg, from the product label.
Herbal Secrets
See all Herbal Secrets products- Name
- Herbal Secrets
- Street Address
- 629 Grove Street
- City
- Jersey City
- State
- NJ
- ZipCode
- 07310
- Web Address
- amazingnutrition.com
Aloe Vera 10,000 mg by Herbal Secrets: Common Questions
Does Aloe Vera 10,000 mg by Herbal Secrets interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will aloe help my constipation?
What are the side effects of taking aloe by mouth?
Can I take this if I'm pregnant?
Is it safe to take while breastfeeding?
Does aloe work for burns or skin problems?
What's the difference between aloe gel and aloe latex?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Aloe Vera 10,000 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Aloe Vera 10,000 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Aloe Vera 10,000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 41 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Aloe 41 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
- Luyckx VA, Ballantine R, Claeys M, et al. Herbal remedy-associated acute renal failure secondary to Cape aloes. Am J Kidney Dis 2002;39:E13. PubMed
- Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S. Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. J Med Food 2004;7:61-6.
- Williams MS, Burk M, Loprinzi CL, et al. Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity. Int J Radiat Oncol Biol Phys 1996;36:345-9. PubMed
- Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract 1999;49:823-8.
- Bottenberg MM, Wall GC, Harvey RL, Habib S. Oral aloe vera-induced hepatitis. Ann Pharmacother 2007;41:1740-3. PubMed
- Rabe C, Musch A, Schirmacher P, et al. Acute hepatitis induced by an Aloe vera preparation: a case report. World J Gastroenterol 2005;11:303-4. PubMed
- Kanat O, Ozet A, Ataergin S. Aloe vera-induced acute toxic hepatitis in a healthy young man. Eur J Int Med 2006;17:589. PubMed
- Mueller SO, Stopper H. Characterization of the genotoxicity of anthraquinones in mammalian cells. Biochim Biophys Acta 1999;1428:406-14. PubMed
- Schorkhuber M, Richter M, Dutter A, et al. Effect of anthraquinone laxatives on the proliferation and urokinase secretion of normal, premalignant and malignant colonic epithelial cells. Eur J Cancer 1998;34:1091-8. PubMed
- Yang HN, Kim DJ, Kim YM, et al. Aloe-induced toxic hepatitis. J Korean Med Sci 2010;25:492-5. PubMed
- Choonhakarn C, Busaracome P, Sripanidkulchai B, et al. A prospective, randomized clinical trial comparing topical aloe vera with 0.1% triamcinolone acetonide in mild to moderate plaque psoriasis. J.Eur.Acad.Dermatol.Venereol. 2010;24:168-72. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. IV. Mechanism of cathartic effect. (3). Biol Pharm Bull. 1994;17:495-7. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. V. Mechanism of cathartic effect. (4). Biol Pharm Bull. 1994;17:651-3. PubMed
- Nelemans FA. Clinical and toxicological aspects of anthraquinone laxatives. Pharmacology. 1976;14 Suppl 1:73-7. PubMed
- Paulsen E, Korsholm L, Brandrup F. A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. J Eur Acad Dermatol Venereol. 2005;19:326-31.
- Huseini HF, Kianbakht S, Hajiaghaee R, et al. Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Planta Med. 2012;78:311-6
- Ferreira, M., Teixeira, M., Silva, E., and Selores, M. Allergic contact dermatitis to Aloe vera. Contact Dermatitis 2007;57(4):278-279.
- Choonhakarn, C., Busaracome, P., Sripanidkulchai, B., and Sarakarn, P. The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial. Br J Dermatol 2008;158(3):573-577. PubMed
- Baretta, Z., Ghiotto, C., Marino, D., and Jirillo, A. Aloe-induced hypokalemia in a patient with breast cancer during chemotherapy. Ann.Oncol. 2009;20(8):1445-1446. PubMed
- Hunter, D. and Frumkin, A. Adverse reactions to vitamin E and aloe vera preparations after dermabrasion and chemical peel. Cutis 1991;47(3):193-196.
- Alvarez-Perea, A., Garcia, A. P., Hernandez, A. L., de, Barrio M., and Baeza, M. L. Urticaria due to aloe vera: a new sensitizer? Ann.Allergy Asthma Immunol. 2010;105(5):404-405. PubMed
- Hogan, D. J. Widespread dermatitis after topical treatment of chronic leg ulcers and stasis dermatitis. CMAJ. 2-15-1988;138(4):336-338.
- Savchak VI. Acute bullous allergic dermatitis due to local application of aloe leaves. Vestnik Dermatologii i Venerologii 1977;12:44-45.
- Nakamura, T. and Kotajima, S. Contact dermatitis from aloe arborescens. Contact Dermatitis 1984;11(1):51. PubMed
- Shoji, A. Contact dermatitis to Aloe arborescens. Contact Dermatitis 1982;8(3):164-167. PubMed
- Morrow, D. M., Rapaport, M. J., and Strick, R. A. Hypersensitivity to aloe. Arch Dermatol. 1980;116(9):1064-1065. DOI
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of AloeAndongensis Extract, Aloe Andongensis Leaf Juice,aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower E
- Bhalang K, Thunyakitpisal P, Rungsirisatean N. Acemannan, a polysaccharide extracted from Aloe vera, is effective in the treatment of oral aphthous ulceration. J Altern Complement Med 2013;19(5):429-34.
- Hajheydari Z, Saeedi M, Morteza-Semnani K, Soltani A. Effect of Aloe vera topical gel combined with tretinoin in treatment of mild and moderate acne vulgaris: a randomized, double-blind, prospective trial. J Dermatolog Treat 2014;25(2):123-9.
- Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep 2012;2012. PubMed
- Lee J, Lee MS, Nam KW. Acute toxic hepatitis caused by an aloe vera preparation in a young patient: a case report with a literature review. Korean J Gastroenterol 2014;64(1):54-8. PubMed
- Guo X, Mei N. Aloe Vera - A Review of Toxicity and Adverse Clinical Effects. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 2016;34(2):77-96.
- Hoogenboom TCH, Patel N, Cook NA, Williams R, Taylor-Robinson SD, Lim AKP. The effect of Aloe vera juice on liver enzymes and hepatic structure in a healthy population. Integr Med (Encinitas) 2020;19(3):30-4.
- Mushtaq S, Mushtaq Z, Sarfraz J, et al. Comparison of effect of aloe vera gel with aspirin and celecoxib on platelet aggregation. Professional Med J. 2020; 27(5):973-978. DOI
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
- Sabbaghzadegan S, Soltani MH, Kamalinejad M, Bahrami M, Kabir A, Dadmehr M. The effect of a standardized capsule of Aloe vera gel on the quality of life in patients with systolic heart failure: A randomized double-blind placebo-controlled clinical trial.
- Lewis ED, Crowley DC, Guthrie N, Evans M. Healthy adults supplemented with a nutraceutical formulation containing Aloe vera gel, rosemary and Poria cocos enhances the effect of influenza vaccination in a randomized, triple-blind, placebo-controlled trial. PubMed
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