Aloe Vera Gel Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Aloe Vera Gel against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Aloe Vera Gel is a dietary supplement by Wonder Laboratories with 1 active ingredient. Its ingredients are commonly taken for minor burns and skin irritation, wound healing, constipation.Based on those ingredients, 461 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Aloe Vera Gel 200:1 conc.. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Aloe Vera Gel by Wonder Laboratories
Ask about any prescription or over-the-counter medication and we check it for interactions with Aloe Vera Gel by Wonder Laboratories — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Aloe Vera Gel by Wonder Laboratories
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This supplement contains one active ingredient: Aloe Vera Gel in a 200:1 concentrated form. The capsule itself is filled with inactive ingredients — soybean oil, gelatin, vegetable glycerin, and white beeswax — which help deliver the aloe.
Does it work?
Moderate evidence
The evidence for aloe vera gel supports a "possibly effective" rating for several uses: acne, obesity, diabetes, psoriasis, burns, and constipation. That means preliminary research is encouraging but not yet definitive.
If you're considering this for any of those purposes, talk with us about whether the evidence is strong enough for your situation.
How safe is it?
Well-documented data
Topical aloe gel is generally well tolerated, but this is an oral capsule — and oral aloe latex carries greater risk, especially at high doses or with long-term use. You may experience abdominal pain, cramps, or diarrhea.
Rare serious effects from extended use include severe potassium loss (hypokalemia), muscle weakness, and heart rhythm problems. The safety data advises against taking oral aloe during pregnancy because the latex may stimulate the uterus and act as a strong laxative.
Avoid it while breastfeeding as well — there isn't enough safety data and the laxative effects are a concern for your baby.
Meds to double-check
Major interaction found
Before taking this aloe product, double-check with us if you take digoxin (Lanoxin) or other heart drugs — that's your top concern. Also flag blood thinners like warfarin, antiplatelet drugs, diabetes medications, diuretics, other laxatives, or any drugs your doctor says are processed by your liver.
No interactions are documented for the inactive ingredients.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.
Aloe vera gel works best for people managing constipation, burns, or skin conditions who don't take heart medications, blood thinners, or diabetes drugs. If you're on any prescription medication — especially digoxin, warfarin, or diuretics — check with us first.
Pregnant and nursing parents should skip it. Talk to your pharmacist about whether this product fits your health picture.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 18, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Aloe Vera Gel, straight from the product label.
| Brand | Wonder Laboratories |
|---|---|
| Net contents | 120 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Dec 18, 2021 |
| DSLD ID | 262355 |
| Product type | Botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Aloe Vera Gel by Wonder Laboratories, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Aloe Vera Gel 200:1 conc. | 75 mg | -- |
Other ingredients: Soybean Oil, Gelatin, Vegetable Glycerin, White Beeswax
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take 3 softgels 1-3 times daily with meals.
Precautions
Tamper evident: Do not use this product if imprinted foil seal under cap is broken or missing.
Keep out of reach of children.
Caution: If you are pregnant or nursing, consult your physician before taking this product.
Formulation
Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)
Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.
Contains no artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no milk, no lactose, no soy, no wheat, no yeast, no fish and is sodium free.
Equivalent to 15,000 mg of pure aloe vera
New higher dose
Gluten free
Made in USA
Storage
Keep tightly closed. Store at room temperature: 59 degrees F - 86 degrees F (15 degrees C - 30 degrees C).
General Statements
Reorder #5901
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Aloe Vera Gel by Wonder Laboratories label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Aloe Vera Gel by Wonder Laboratories
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size3 Softgel(s) Dosage formSoftgel Capsule Servings per container40 Amounts shown are per serving.
Aloe Vera Gel 200:1 conc.
Interacts with461 drugs
Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a str...
Aloe Vera Gel 200:1 conc. monograph & interactionsOther (inactive) ingredients: Soybean Oil, Gelatin, Vegetable Glycerin, White Beeswax. These complete the product’s ingredient list but are not active constituents.
Aloe Vera Gel by Wonder Laboratories Drug Interactions
HelloPharmacist Interaction Report
Wonder Laboratories' Aloe Vera Gel is a single-ingredient supplement that does interact with several medication types, and the most serious concern is digoxin (Lanoxin), a heart drug.
Overuse of aloe latex can deplete potassium, which raises the risk of digoxin toxicity — a Major severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Aloe also carries Moderate interactions with blood thinners (anticoagulants) and antiplatelet drugs like aspirin and warfarin; the concern is increased bleeding risk. It may lower blood sugar (hypoglycemia) when used with diabetes medications, so close monitoring is needed.
Diuretics and stimulant laxatives pose a Moderate risk because aloe can compound potassium loss and fluid loss, respectively. Warfarin users face particular caution — aloe's laxative effects can trigger diarrhea, which strengthens warfarin's blood-thinning action and raises bleeding risk.
Aloe also has a Minor interaction with certain drugs metabolized by the liver enzyme CYP1A2; aloe may lower their blood levels and reduce how well they work. Altogether, these interactions span 460 individual medications.
Use the medication checker below to confirm whether any of your prescriptions are affected before you start this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Aloe Vera Gel?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Aloe Vera Gel interact with 461 drugs. Click any drug to see the details.
1 of the 1 ingredient in Aloe Vera Gel interact with drugs. Each result below shows which ingredient is responsible. Aloe Vera Gel 200:1 conc.
DigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Digoxin (lanoxin) Major
Interaction Summary
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Read the full Aloe Vera Gel 200:1 Conc. + Digoxin interactionAbciximabReoPro
How Abciximab interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Antidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Cytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera Gel 200:1 Conc. + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Anticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Cytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera Gel 200:1 Conc. + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Anticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Acetaminophen, Ibuprofen interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Cytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera Gel 200:1 Conc. + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Antidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Antidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Antidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Antidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Antidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Anticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Antidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera Gel 200:1 Conc. + Argatroban interactionArmodafinilNuvigil
How Armodafinil interacts with Aloe Vera Gel — through 1 ingredient. Tap an ingredient for the detail:
Aloe Vera Gel 200:1 Conc.Stimulant Laxatives Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Read the full Aloe Vera Gel 200:1 Conc. + Armodafinil interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Aloe Vera Gel with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Aloe Vera Gel 200:1 conc.
Digoxin (Lanoxin)
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Overuse of aloe latex can increase the risk of adverse effects from cardiac glycoside drugs, such as digoxin, due to potassium depletion. Overuse of aloe, along with cardiac glycoside drugs, can increase the risk of toxicity.
Anticoagulant/Antiplatelet Drugs
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aloe gel can inhibit platelet aggregation. This inhibition was greater than that seen with celecoxib, but less than that seen with aspirin.
Antidiabetes Drugs
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Preliminary clinical research suggests aloe gel might lower blood glucose levels and have additive effects when used with antidiabetes drugs. Monitor blood glucose levels closely.
Diuretic Drugs
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of aloe latex might compound diuretic-induced potassium loss, increasing the risk of hypokalemia.
Stimulant Laxatives
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Due to cathartic laxative effects of aloe latex, concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.
Warfarin (Coumadin)
Theoretically, aloe latex might increase the risk of bleeding when taken with warfarin.
Aloe latex has stimulant laxative effects. In some people aloe latex can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of aloe vera.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that aloe extract induces CYP1A2 enzymes.
Brand information
Manufacturer and brand details for Aloe Vera Gel, from the product label.
Wonder Laboratories
See all Wonder Laboratories products- Name
- Wonder Laboratories
- Street Address
- 115 S.C.T. Ct.
- City
- White House
- State
- TN
- ZipCode
- 37188
Aloe Vera Gel by Wonder Laboratories: Common Questions
Does Aloe Vera Gel by Wonder Laboratories interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this aloe gel if I'm on warfarin or another blood thinner?
What are the most common side effects of oral aloe?
Is this aloe gel safe to take while I'm pregnant?
Can this help me lose weight?
What does '200:1 concentration' mean?
Does this product have any fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Aloe Vera Gel is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Aloe Vera Gel’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Aloe Vera Gel's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 41 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Aloe 41 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
- Luyckx VA, Ballantine R, Claeys M, et al. Herbal remedy-associated acute renal failure secondary to Cape aloes. Am J Kidney Dis 2002;39:E13. PubMed
- Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S. Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. J Med Food 2004;7:61-6.
- Williams MS, Burk M, Loprinzi CL, et al. Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity. Int J Radiat Oncol Biol Phys 1996;36:345-9. PubMed
- Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract 1999;49:823-8.
- Bottenberg MM, Wall GC, Harvey RL, Habib S. Oral aloe vera-induced hepatitis. Ann Pharmacother 2007;41:1740-3. PubMed
- Rabe C, Musch A, Schirmacher P, et al. Acute hepatitis induced by an Aloe vera preparation: a case report. World J Gastroenterol 2005;11:303-4. PubMed
- Kanat O, Ozet A, Ataergin S. Aloe vera-induced acute toxic hepatitis in a healthy young man. Eur J Int Med 2006;17:589. PubMed
- Mueller SO, Stopper H. Characterization of the genotoxicity of anthraquinones in mammalian cells. Biochim Biophys Acta 1999;1428:406-14. PubMed
- Schorkhuber M, Richter M, Dutter A, et al. Effect of anthraquinone laxatives on the proliferation and urokinase secretion of normal, premalignant and malignant colonic epithelial cells. Eur J Cancer 1998;34:1091-8. PubMed
- Yang HN, Kim DJ, Kim YM, et al. Aloe-induced toxic hepatitis. J Korean Med Sci 2010;25:492-5. PubMed
- Choonhakarn C, Busaracome P, Sripanidkulchai B, et al. A prospective, randomized clinical trial comparing topical aloe vera with 0.1% triamcinolone acetonide in mild to moderate plaque psoriasis. J.Eur.Acad.Dermatol.Venereol. 2010;24:168-72. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. IV. Mechanism of cathartic effect. (3). Biol Pharm Bull. 1994;17:495-7. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. V. Mechanism of cathartic effect. (4). Biol Pharm Bull. 1994;17:651-3. PubMed
- Nelemans FA. Clinical and toxicological aspects of anthraquinone laxatives. Pharmacology. 1976;14 Suppl 1:73-7. PubMed
- Paulsen E, Korsholm L, Brandrup F. A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. J Eur Acad Dermatol Venereol. 2005;19:326-31.
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