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Dietary supplement

Alpha-GPC Ingredients & Drug Interactions

by Cynthia Thurlow Powered by MDLogic

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Alpha-GPC is a dietary supplement by Cynthia Thurlow Powered by MDLogic with 1 active ingredient. Its ingredients are commonly taken for memory and learning support, age-related cognitive decline, alzheimer's disease and dementia (under study).Based on those ingredients, 16 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Alpha-GPC. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Alpha-GPC by Cynthia Thurlow Powered by MDLogic

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: alpha-GPC, a compound that delivers choline to your brain. The capsules also hold inactive ingredients (olive oil, a plant-based capsule coating, vitamin E acetate, and chlorophyllin) that support absorption and shelf life.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: enhanced cognition function and neurological protection.
  • We looked for evidence on: Cognitive function, Alzheimer disease, Vascular dementia, memory, learning, age-related cognitive decline.
  • The strongest evidence on file: Alpha-gpc is rated "Possibly Effective" for Alzheimer disease (Natural Medicines).
  • Also on file: Alpha-gpc is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Vascular dementia.

The evidence for alpha-GPC is mixed. It's rated possibly effective for Alzheimer disease.

For cognitive function, vascular dementia, stroke, and brain tumor, there isn't enough reliable evidence yet to say whether it works. If you're considering it for a specific condition, that's worth discussing with your doctor.

The evidence, ingredient by ingredient Alpha-gpc

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Alpha-GPC is generally well tolerated in the studies we have, but long-term safety hasn't been fully worked out. Rare side effects reported orally include dizziness, headache, insomnia, nausea, vomiting, heartburn, and diarrhea.

One concern: alpha-GPC used for at least 2 months has been rarely linked to an elevated stroke risk compared with non-users or short-term users. The product label advises against use unless your doctor directs it, given incomplete safety information.

Side effects, ingredient by ingredient Alpha-gpc

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Alpha-gpc.
  • The most serious interaction on file is rated Minor.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking alpha-GPC, check if you use a scopolamine patch (Transderm Scop) for motion sickness or nausea — alpha-GPC may reduce its effects. The product interacts with medications in that drug family, so run your exact medications through the search tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Alpha-GPC may interest people exploring support for Alzheimer disease, but evidence for other brain and cognitive claims is still uncertain. Because long-term safety isn't fully established and a potential stroke risk exists with prolonged use, talk to your pharmacist or doctor before starting — especially if you're older, have a stroke history, or take motion-sickness medication.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Alpha-GPC, straight from the product label.

Brand Cynthia Thurlow Powered by MDLogic
Barcode (UPC) 897395002913
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2025
DSLD ID 320653
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Alpha-GPC by Cynthia Thurlow Powered by MDLogic, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
897395002913
IngredientAmount% DV
Alpha-GPC300 mg--

Other ingredients: Extra Virgin Olive Oil, Hypromellose, D-Alpha Tocopherol Acetate, Chlorophyllin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Unlock your brain's potential with Alpha GPC - your daily ally for enhanced cognition function, exercise performance, and neurological protection.

Gluten Free BPA Free

Brain health Exercise performance Neuro protection

Lab tested for contaminants, including heavy metals and mold.

Precautions

Warning: Consult with a health care professional before use and/or if you are pregnant, lactating, or undergoing treatment for a medical condition.

Do not exceed recommended dosage. Discontinue use if any adverse reactions occur and contact a health care professional.

Keep out of reach of children.

Contains no milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, or shrimp), tree nuts, wheat, peanuts, soybean, or sesame. No artificial colors or flavors. No toxic fillers, including stearates and palmitates. Product contains no phthalates.

Storage

Store tightly closed in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Made in the USA from global ingredients Manufactured by a GMP Certified Company

Brand IP Statement(s)

Supplementing Life MD Logic Est. 2005

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Recommended use: As a dietary supplement, take two (2) capsules daily, or as recommended by a healthcare professional.

General Statements

Scan me!

See for yourself

Alpha-GPC by Cynthia Thurlow Powered by MDLogic label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Alpha-GPC by Cynthia Thurlow Powered by MDLogic

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Alpha-GPC

Interacts with
16 drugs
300 mg per serving

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition...

Alpha-GPC monograph & interactions

Other (inactive) ingredients: Extra Virgin Olive Oil, Hypromellose, D-Alpha Tocopherol Acetate, Chlorophyllin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Alpha-GPC by Cynthia Thurlow Powered by MDLogic Drug Interactions

Want to check YOUR meds against Alpha-GPC?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
16Drugs
16 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Alpha-GPC with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Alpha-GPC1 drug type · 16 drugs

Scopolamine (Transderm Scop)

Theoretically, alpha-GPC might decrease the effects of scopolamine.
A small clinical study shows that alpha-GPC can partially counteract the attention and memory impairment effects caused by scopolamine given intramuscularly. Whether alpha-GPC can decrease the beneficial anti-motion sickness effects of the scopolamine patch (Transderm Scop) is unclear.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Alpha-GPC, from the product label.

Cynthia Thurlow Powered by MDLogic

See all Cynthia Thurlow Powered by MDLogic products
Name
MD Logic Wellness Inc. for MD Logic Health
State
Florida
Phone Number
1-877-629-8711
Web Address
www.mdlogichealth.com
Pharmacist Counseling Corner

Alpha-GPC by Cynthia Thurlow Powered by MDLogic: Common Questions

Does Alpha-GPC by Cynthia Thurlow Powered by MDLogic interact with any medications?
Yes. Based on its ingredients, Alpha-GPC has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Alpha-GPC contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is alpha-GPC safe to take long-term?
The studies we have show it's generally well tolerated in the short term, but long-term safety hasn't been fully established. Given that risk of stroke has been linked to use for 2 months or longer, talk with your pharmacist or doctor before taking it regularly.
What is alpha-GPC, and what does it do?
Alpha-GPC is a compound that delivers choline to your brain. It's thought to support memory and cognitive function, though the evidence is stronger for Alzheimer disease than for other brain conditions.
Can I take this if I use a scopolamine patch?
Not without checking with your pharmacist first. Alpha-GPC may decrease the effects of the scopolamine patch (Transderm Scop), so your doctor needs to weigh whether that's a concern for your situation.
What side effects might I experience?
Most people tolerate it well, but rare side effects include dizziness, headache, insomnia, nausea, heartburn, and diarrhea. Serious side effects are very rare but can include stroke, especially with use for 2 months or longer.
Does this work for memory and focus?
The evidence for general cognitive function and memory isn't strong enough to say yet. It's rated possibly effective for Alzheimer disease, but for other brain conditions there isn't reliable evidence backing it up.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Alpha-GPC label
Sources

Sources & How We Checked

Alpha-GPC's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Alpha-gpc 4 references
  1. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to the evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res 1991;19:330-41.
  2. Barbagallo Sangiorgi G, Barbagallo M, Giordano M, et al. Alpha-glycerophosphocholine in the mental recovery of cerebral ischemic attacks: An Italian multicenter clinical trial. Ann N Y Acad Sci 1994;717:253-69. PubMed
  3. Canal N, Franceschi M, Alberoni M, et al. Effect of L-alpha-glyceryl-phosphorylcholine on amnesia caused by scopolamine. Int J Clin Pharmacol Ther Toxicol 1991;29:103-7.
  4. Lee G, Choi S, Chang J, et al. Association of L-a glycerylphosphorylcholine with subsequent stroke risk after 10 Years. JAMA Netw Open 2021;4(11):e2136008.

See these in context on the Alpha-gpc monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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