Arjuna Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Arjuna against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Arjuna is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for heart health and circulation, digestive problems (constipation, diarrhea), cholesterol support.Based on those ingredients, 933 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Arjuna dried bark liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Arjuna by Herbal Terra
Ask about any prescription or over-the-counter medication and we check it for interactions with Arjuna by Herbal Terra — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Arjuna by Herbal Terra
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: certified organic Arjuna dried bark liquid extract. Arjuna is a traditional plant used in herbal medicine, and the extract form here means the active compounds have been concentrated from the bark.
The product also contains menstruum, which is the liquid used to prepare the extract — that's an inactive ingredient, not a therapeutic component.
Does it work?
Not established
The evidence for Arjuna isn't established yet in the data we hold. Studies haven't yielded reliable proof that it works for obesity, high cholesterol, high blood pressure, or angina — so far, the evidence is insufficient to rate it for any of these uses.
If you're considering it for a specific condition, talk it over with your doctor or pharmacist about what the current science actually supports.
How safe is it?
Some data gaps
Arjuna appears to be generally well tolerated in short-term studies, but long-term safety data are limited and quality varies between products — so we can't guarantee how safe it is over months or years. The safety data advises against using it during pregnancy or while breastfeeding; there isn't enough information to know it's safe in those windows.
If you're pregnant, breastfeeding, or planning either, talk with your doctor or pharmacist before taking this product.
Meds to double-check
Moderate interaction found
Before taking Arjuna, double-check your medications if you're on any of these: blood thinners or antiplatelet drugs (Moderate risk of increased bleeding), drugs broken down by your liver's CYP2D6, CYP2C9, or CYP3A4 enzymes (Moderate risk of drug buildup — this includes many heart and blood pressure medications, antidepressants, and others), diabetes medications (Moderate risk of low blood sugar), chlorzoxazone (muscle relaxer), or omeprazole (acid reflux medication). Talk with your own pharmacist or doctor about whether this product is right for you.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.
This product is marketed for heart and cholesterol support, but the evidence for it isn't strong yet. More important: it interacts with a large number of medications by slowing how your liver clears them, and it may increase bleeding risk with blood thinners.
If you take any prescription drugs, check them against the search tool on this page, and have that conversation with your own doctor or pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Arjuna, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 7429523264233 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Oct 23, 2020 |
| DSLD ID | 233951 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic, Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Arjuna by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| certified organic Arjuna dried bark liquid extract | 970 mg | -- |
Other ingredients: Menstruum
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Origin of plant material: India.
Manufactured in the USA in an FDA registered facility
Sugar free
Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Super concentrated liquid herbal extract
Non GMO
No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free
Suggested/Recommended/Usage/Directions
Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.
FDA Disclaimer Statement
Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Caution May have contraindications.
Do not use if you are allergic to any ingredients.
Consult a physician before using during pregnancy, if nursing, or if you are on any medications.
Keep out of the reach of children.
Storage
Store in a cool, dry, dark place.
Formula
Terminalia arjuna
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
Made in USA Made in an FDA registered facility Natural Gluten Free
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Arjuna by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Arjuna by Herbal Terra
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Certified organic Arjuna dried bark liquid extract
Interacts with933 drugs
Terminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness purposes....
Certified organic Arjuna dried bark liquid extract monograph & interactionsOther (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.
Arjuna by Herbal Terra Drug Interactions
HelloPharmacist Interaction Report
Arjuna by Herbal Terra is a single-ingredient liquid extract that does interact with a range of medications.
The most serious concern involves three major enzyme systems in your liver (CYP2D6, CYP2C9, and CYP3A4) that break down many common drugs — this extract can slow that process down, which means your medication levels could build up and cause side effects. The extract also theoretically increases bleeding risk if you're taking blood thinners or antiplatelet drugs (like warfarin or aspirin), because in lab studies it showed anticlotting effects.
Read the full breakdown — every affected drug type, severity by severity
Beyond that, there are Moderate interactions with blood sugar medications, and also with two specific drugs: chlorzoxazone (a muscle relaxer) and omeprazole (a heartburn medication) — animal research suggests this extract can raise their blood levels. Altogether, these interactions span 934 individual medications.
Before you start this product, run your exact prescriptions through the search tool below — especially if you take heart or blood pressure drugs, antidepressants, blood thinners, diabetes medications, or stomach acid reducers.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Arjuna?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Arjuna interact with 933 drugs. Click any drug to see the details.
1 of the 1 ingredient in Arjuna interact with drugs. Each result below shows which ingredient is responsible. certified organic Arjuna dried bark liquid extract
Aspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAspirin, DipyridamoleAggrenox, Asasantin Retard
How Aspirin, Dipyridamole interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Aspirin, Dipyridamole interactionAspirin, Ethoheptazine, MeprobamateEquagesic
How Aspirin, Ethoheptazine, Meprobamate interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Aspirin, Ethoheptazine, Meprobamate interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Aspirin, Hydrocodone interactionAspirin, MeprobamateMicrainin
How Aspirin, Meprobamate interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Aspirin, Meprobamate interactionAspirin, MethocarbamolRobaxisal
How Aspirin, Methocarbamol interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Aspirin, Methocarbamol interactionAspirin, OmeprazoleYosprala
How Aspirin, Omeprazole interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates +2 Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Aspirin, Omeprazole interactionAspirin, OxycodonePercodan
How Aspirin, Oxycodone interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Aspirin, Oxycodone interactionAspirin, PentazocineTalwin Compound
How Aspirin, Pentazocine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Aspirin, Pentazocine interactionAtazanavirReyataz
How Atazanavir interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Atazanavir interactionAtazanavir, CobicistatEvotaz
How Atazanavir, Cobicistat interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Atazanavir, Cobicistat interactionAtogepantQulipta
How Atogepant interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Atogepant interactionAtomoxetineStrattera
How Atomoxetine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Atomoxetine interactionAtorvastatinAtorvaliq
How Atorvastatin interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Atorvastatin interactionAtorvastatin CalciumLipitor
How Atorvastatin Calcium interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Atorvastatin Calcium interactionAtropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, ScopolamineAtrohist Plus, Pro Tuss, Ru-tuss, Stahist
How Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interactionAtropine, MeperidineAtropine, Meperidine
How Atropine, Meperidine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Atropine, Meperidine interactionAtropine, Morphine SulfateAtropine, Morphine Sulfate
How Atropine, Morphine Sulfate interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Atropine, Morphine Sulfate interactionAvacopanTavneos
How Avacopan interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Avacopan interactionAvanafilStendra
How Avanafil interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Avanafil interactionAvapritinibAyvakit
How Avapritinib interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Avapritinib interactionAxitinibInlyta
How Axitinib interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Axitinib interactionAzelastine Hydrochloride, Fluticasone PropionateDymista
How Azelastine Hydrochloride, Fluticasone Propionate interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Azelastine Hydrochloride, Fluticasone Propionate interactionAzilsartanEdarbi
How Azilsartan interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Azilsartan, Chlorthalidone interactionBazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Bazedoxifene Acetate, Conjugated Estrogens interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Arjuna Dried Bark Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Certified Organic Arjuna Dried Bark Liquid Extract + Beclomethasone Dipropionate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Arjuna with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
certified organic Arjuna dried bark liquid extract
Anticoagulant/Antiplatelet Drugs
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
In vitro, Terminalia arjuna bark extract inhibits platelet aggregation, decreases platelet activation, and shows antithrombotic properties.
Antidiabetes Drugs
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Animal and in vitro research shows that Terminalia bellirica and Terminalia chebula fruit and seed extract have hypoglycemic effects.
Chlorzoxazone (Parafon Forte, Paraflex)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of chlorzoxazone increases blood levels of chlorzoxazone and decreases chlorzoxazone clearance. It is speculated that Terminalia chebula reduces the metabolism of chlorzoxazone by inhibiting cytochrome P450 2E1.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2C9 enzymes and reduces CYP2C9 substrate metabolism.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2D6 enzymes and reduces CYP2D6 substrate metabolism.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP3A4 enzymes and reduces CYP3A4 substrate metabolism.
Omeprazole (Prilosec)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from omeprazole.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of omeprazole increases blood levels of omeprazole and decreases omeprazole clearance. It is speculated that Terminalia chebula reduces the metabolism of omeprazole by inhibiting cytochrome P450 2C19.
Brand information
Manufacturer and brand details for Arjuna, from the product label.
Arjuna by Herbal Terra: Common Questions
Does Arjuna by Herbal Terra interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is Arjuna safe during pregnancy or breastfeeding?
What does Arjuna actually do?
How long is it safe to take this product?
Does it matter if I take Arjuna with food?
What's menstruum — is it a filler or something else?
Can I take Arjuna if I'm on a blood thinner like warfarin?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Arjuna is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Arjuna’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Arjuna's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 9 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Terminalia 9 references
- Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
- Rao, N. K. and Nammi, S. Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats. BMC.Complement Altern.Med 2006;6:17. PubMed
- Murali, Y. K., Anand, P., Tandon, V., Singh, R., Chandra, R., and Murthy, P. S. Long-term effects of Terminalia chebula Retz. on hyperglycemia and associated hyperlipidemia, tissue glycogen content and in vitro release of insulin in streptozotocin induced
- Senthilkumar, G. P. and Subramanian, S. Evaluation of antioxidant potential of Terminalia chebula fruits studies in streptozotocin-induced diabetic rats. Pharmaceutical Biology (Netherlands) 2007;45:511-518.
- Malik N, Dhawan V, Bahl A, Kaul D. Inihbitory effects of Terminalia arjuna on platelet activation in vitro in healthy subjects and patients with coronary artery disease. Platelets. 2009;20(3):183-1190.
- Varghese A, Savai J, Pandita N, Gaud RS. In vitro modulatory effects of Terminalia arjuna, arjunic acid, arjunetin, and arjungenin on CYP3A4, CYP2D6, and CYP2C9 enzyme activity in human liver microsomes. Toxicology Reports. 2015(2):806-16. PubMed
- Wu G, Dong Z, Dong J, et al. Effects of mongolian medicine Terminalia chebula Retz. on 6 CYP450 enzymes in rats. Int J Clin Exp Pathol 2020;13(12):3128-3138.
- Das A, Naveen J, Sreerama YN, Gnanesh Kumar BS, Baskaran V. Low-glycemic foods with wheat, barley and herbs (Terminalia chebula, Terminalia bellerica and Emblica officinalis) inhibit a-amylase, a-glucosidase and DPP-IV activity in high fat and low dose st
- Eltimamy M, Elshamarka M, Aboelsaad M, Sayed M, Moawad H. Effects of alcoholic extract of Terminalia Chebula dried fruit on blood biochemical profile in diabetic rats. J Diabetes Metab Disord 2022;21(1):159-170. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC