ArthriVarx Ingredients & Drug Interactions
What is this page for?
First and foremost: checking ArthriVarx against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
ArthriVarx is a dietary supplement by Innovus Pharmaceuticals with 2 active ingredients. Its ingredients are commonly taken for common cold and flu symptoms, upper respiratory infections, sore throat.Based on those ingredients, 413 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Andrographis paniculata 4:1 extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against ArthriVarx by Innovus Pharmaceuticals
Ask about any prescription or over-the-counter medication and we check it for interactions with ArthriVarx by Innovus Pharmaceuticals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of ArthriVarx by Innovus Pharmaceuticals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
ArthriVarx has two active ingredients. Andrographis paniculata 4:1 extract is a concentrated plant extract traditionally used in herbal medicine.
Hyaluronic acid (HA) is a naturally occurring compound found in the body that helps retain moisture in tissues. The capsule also contains inactive ingredients — rice powder, gelatin, magnesium stearate, and silica — which are fillers and binders that help hold the supplement together.
Does it work?
Moderate evidence
Andrographis has been rated Possibly Effective for ulcerative colitis, tonsillopharyngitis (sore throat from inflammation), and osteoarthritis. For familial Mediterranean fever, the evidence isn't established enough to rate it.
Hyaluronic acid is rated Possibly Effective for dry eye and venous leg ulcers; the evidence for aging skin, hay fever, and sexual dysfunction is insufficient. The data we hold doesn't show that this combination has been studied together for any particular use.
How safe is it?
Well-documented data
Andrographis is generally well tolerated in short-term use, but long-term safety hasn't been firmly established. At higher doses or when used for more than 14 days, side effects become more likely — these include abdominal discomfort, diarrhea, nausea, dizziness, headache, fatigue, taste changes, skin reactions like rash or itching, and rarely severe allergic reactions.
Hyaluronic acid is generally well tolerated when taken by mouth or applied to skin, though topical use has occasionally caused eczema, itching, or local infections. Do not use andrographis during pregnancy because animal studies raise concerns about reproductive effects, and don't use it while breastfeeding — there isn't enough safety information.
For hyaluronic acid during pregnancy or breastfeeding, there isn't enough data to know either way; talk with your doctor or pharmacist for personalized advice.
Meds to double-check
Moderate interaction found
Before you take ArthriVarx, double-check if you're on blood thinners or antiplatelet drugs (Moderate severity), blood pressure medications (Moderate), or immunosuppressants (Moderate). Also verify that you're not taking etoricoxib, celecoxib, or glipizide, which have Minor documented interactions.
If you take any of these, ask your pharmacist whether this product is right for you.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
ArthriVarx may help with certain types of arthritis or sore throat, but if you take blood thinners, blood pressure medications, or immunosuppressants, you need to check with your pharmacist first. Avoid it in pregnancy and while breastfeeding.
It's generally well tolerated short-term, but long-term safety data is limited.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2018.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about ArthriVarx, straight from the product label.
| Brand | Innovus Pharmaceuticals |
|---|---|
| Barcode (UPC) | 357483000257 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Oct 25, 2018 |
| DSLD ID | 181924 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for ArthriVarx by Innovus Pharmaceuticals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Andrographis paniculata 4:1 extract | 250 mg | -- |
| HA | 30 mg | -- |
Other ingredients: Rice powder, Gelatin, Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take one (1) to two (2) capsules daily with a meal or as directed by your healthcare practitioner.
Precautions
Warning: Do not use in person under the age of 18. Ask your doctor before using ArthriVarx.
Do not use if allergic to any ingredient in ArthriVarx.
Stop using if you experience any side effect.
Do not use if pregnant or nursing.
Do not use if inner seal or outer neck band is broken.
Keep out of the reach of children.
Storage
Caution: Keep tightly closed and store in a cool dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
From the maker of Apeaz Ultra
General Statements
Joint Supplement
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
ArthriVarx by Innovus Pharmaceuticals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in ArthriVarx by Innovus Pharmaceuticals
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Andrographis paniculata 4:1 extract
Interacts with413 drugs
Andrographis is a bitter Asian herb traditionally used for colds, flu, and infections, and some studies suggest it may ease cold symptoms and shorten...
Andrographis paniculata 4:1 extract monograph & interactionsHA
No knowninteractions
Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...
HA monograph & interactionsOther (inactive) ingredients: Rice powder, Gelatin, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
ArthriVarx by Innovus Pharmaceuticals Drug Interactions
HelloPharmacist Interaction Report
ArthriVarx by Innovus Pharmaceuticals contains andrographis, which does interact with several medication types.
The most serious concern is with blood thinners and antiplatelet drugs (medications like warfarin or aspirin) — andrographis may increase your bleeding risk because animal studies show it has antiplatelet effects. This is rated Moderate severity.
Read the full breakdown — every affected drug type, severity by severity
Andrographis also has Moderate interactions with blood pressure medications (it may lower your blood pressure further) and with immunosuppressants (it may interfere with how they work). There are Minor interactions documented with three specific drugs: etoricoxib (a pain reliever), celecoxib, and glipizide (a diabetes medication) — the clinical importance of these is unclear, but they're worth discussing with your pharmacist.
The second ingredient, hyaluronic acid (HA), has no known interactions documented in our data. Altogether, these interactions span 407 individual medications.
Before you start ArthriVarx, run your exact medications through the interaction checker on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against ArthriVarx?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in ArthriVarx interact with 413 drugs. Click any drug to see the details.
1 of the 2 ingredients in ArthriVarx interact with drugs. Each result below shows which ingredient is responsible. Andrographis paniculata 4:1 extract
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Andrographis Paniculata 4:1 Extract + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Andrographis Paniculata 4:1 Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Andrographis Paniculata 4:1 Extract + Abrocitinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Andrographis Paniculata 4:1 Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Andrographis Paniculata 4:1 Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Andrographis Paniculata 4:1 Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Andrographis Paniculata 4:1 Extract + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Acetazolamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Andrographis Paniculata 4:1 Extract + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Adalimumab-fkjp interactionAlefaceptAmevive
How Alefacept interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Alemtuzumab interactionAliskirenTekturna
How Aliskiren interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Aliskiren interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Andrographis Paniculata 4:1 Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Andrographis Paniculata 4:1 Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Andrographis Paniculata 4:1 Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with ArthriVarx — through 1 ingredient. Tap an ingredient for the detail:
Andrographis Paniculata 4:1 ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Andrographis Paniculata 4:1 Extract + Amlodipine Besylate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in ArthriVarx with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Andrographis paniculata 4:1 extract
Anticoagulant/Antiplatelet Drugs
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal and laboratory studies suggest that andrographis has antiplatelet effects.
Antihypertensive Drugs
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Animal research suggests that andrographis has hypotensive effects.
Immunosuppressants
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Laboratory research suggests that andrographolide has immunostimulant activity.
Celecoxib (Celebrex)
Theoretically, andrographis extract might increase the maximum concentration and time to peak concentration of celecoxib. The clinical significance of these changes is unclear.
Animal research suggests that andrographis extract taken orally increases the maximum concentration and time to peak concentration of celecoxib but does not appear to impact the area under the curve.
Etoricoxib (Arcoxia)
Theoretically, andrographis might decrease the absorption of etoricoxib, although the clinical significance is unclear.
Animal research shows that andrographis extract, or the constituent andrographolide, taken orally with etoricoxib decreases the bioavailability of etoricoxib. However, this reduced bioavailability is not correlated with a reduction in the anti-inflammatory effects of etoricoxib in arthritic mice models. The clinical significance of this interaction is unclear.
Glipizide (Glucotrol)
Theoretically, andrographis extract might increase the maximum concentration and area under the curve of glipizide; however, opposite effects are seen with the constituent, andrographolide. The clinical significance of this interaction is unclear.
Animal research suggests that andrographis extract taken orally with glipizide in diabetes-induced rats increases the maximum concentration and area under the curve of glipizide. However, the opposite effect is seen with the constituent, andrographolide, in which the maximum concentration and area under the curve are decreased when taken with glipizide.
Brand information
Manufacturer and brand details for ArthriVarx, from the product label.
Innovus Pharmaceuticals
See all Innovus Pharmaceuticals products- Name
- Innovus Pharmaceuticals, Inc.
- City
- San Diego
- State
- CA
- ZipCode
- 92122
- Phone Number
- 1-800-748-6119
- Web Address
- www.arthrivarx.com
ArthriVarx by Innovus Pharmaceuticals: Common Questions
Does ArthriVarx by Innovus Pharmaceuticals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help my osteoarthritis?
Can I take this if I'm pregnant?
Can I breastfeed while taking ArthriVarx?
What side effects should I expect?
What's hyaluronic acid doing in here?
Is it safe to take long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if ArthriVarx is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind ArthriVarx’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Andrographis
Interacts with 413 drugsAndrographis is a bitter Asian herb traditionally used for colds, flu, and infections, and some studies suggest it may ease cold symptoms and shorten how long they last. The evidence is limi...
Read the full Andrographis monograph → Herb & supplement monographHyaluronic Acid
Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin moisture and joint comfort, and the evi...
Read the full Hyaluronic Acid monograph →Sources & How We Checked
ArthriVarx's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Andrographis 26 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Thamlikitkul V, Dechatiwongse T, Theerapong S, et al. Efficacy of Andrographis paniculata, Nees for pharyngotonsillitis in adults. J Med Assoc Thai 1991;74:437-42.
- Zhang CY, Tan BK. Mechanisms of cardiovascular activity of Andrographis paniculata in the anaesthetized rat. J Ethnopharmacol 1997;56:97-101. PubMed
- Zhao HY, Fang WY. Antithrombotic effects of Andrographis paniculata nees in preventing myocardial infarction. Chin Med J (Engl) 1991;104:770-5.
- Amroyan E, Gabrielian E, Panossian A, et al. Inhibitory effect of andrographolide from Andrographis paniculata on PAF-induced platelet aggregation. Phytomedicine 1999;6:27-31. PubMed
- Zhang C, Kuroyangi M, Tan BK. Cardiovascular activity of 14-deoxy-11,12-didehydroandrographolide in the anaesthetised rat and isolated right atria. Pharmacol Res 1998;38:413-7. PubMed
- Puri A, Saxena R, Saxena RP, et al. Immunostimulant agents from Andrographis paniculata. J Nat Prod 1993;56:995-9. PubMed
- Melchoir J, Spasov AA, Ostrovskij OV, et al. Double-blind, placebo-controlled pilot and phase III study of activity of standardized Andrographis paniculata Herba Nees extract fixed combination (Kan Jang) in the treatment of uncomplicated upper-respirator
- Calabrese C, Berman SH, Babish JG, et al. A phase I trial of andrographolide in HIV positive patients and normal volunteers. Phytother Res 2000;14:333-8. PubMed
- Gabrielian ES, Shukarian AK, Goukasova GI, et al. A double blind, placebo-controlled study of Andrographis paniculata fixed combination Kan Jang in the treatment of acute upper respiratory tract infections including sinusitis. Phytomedicine 2002;9:589-97 PubMed
- Poolsup N, Suthisisang C, Prathanturarug S, et al. Andrographis paniculata in the symptomatic treatment of uncomplicated upper respiratory tract infection: systematic review of randomized controlled trials. J Clin Pharm Ther 2004;29:37-45. PubMed
- Coon JT, Ernst E. Andrographis paniculata in the treatment of upper respiratory tract infections: a systematic review of safety and efficacy. Planta Med 2004;70:293-8.
- Kligler, B., Ulbricht, C., Basch, E., Kirkwood, C. D., Abrams, T. R., Miranda, M., Singh Khalsa, K. P., Giles, M., Boon, H., and Woods, J. Andrographis paniculata for the treatment of upper respiratory infection: a systematic review by the natural standa
- Burgos, R. A., Hancke, J. L., Bertoglio, J. C., Aguirre, V., Arriagada, S., Calvo, M., and Caceres, D. D. Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled tria
- Saxena, R. C., Singh, R., Kumar, P., Yadav, S. C., Negi, M. P., Saxena, V. S., Joshua, A. J., Vijayabalaji, V., Goudar, K. S., Venkateshwarlu, K., and Amit, A. A randomized double blind placebo controlled clinical evaluation of extract of Andrographis pa
- Tang, T., Targan, S. R., Li, Z. S., Xu, C., Byers, V. S., and Sandborn, W. J. Randomised clinical trial: herbal extract HMPL-004 in active ulcerative colitis - a double-blind comparison with sustained release mesalazine. Aliment.Pharmacol Ther 2011;33(2) PubMed
- Sandborn, W. J., Targan, S. R., Byers, V. S., Rutty, D. A., Mu, H., Zhang, X., and Tang, T. Andrographis paniculata extract (HMPL-004) for active ulcerative colitis. Am J Gastroenterol. 2013;108(1):90-98. PubMed
- Melchior, J., Palm, S., and Wikman, G. Controlled clinical study of standardized Andrographis paniculata extract in common cold - a pilot trial. Phytomedicine. 1997;3(4):315-318. PubMed
- Balap A, Atre B, Lohidasan S, et al. Pharmacokinetic and pharmacodynamic herb-drug interaction of Andrographis paniculata (Nees) extract and andrographolide with etoricoxib after oral administration in rats. J Ethnopharmacol. 2016 May 13;183:9-17. PubMed
- Bertoglio JC, Baumgartner M, Palma R, et al. Andrographis paniculata decreases fatigue in patients with relapsing-remitting multiple sclerosis: a 12-month double-blind placebo-controlled pilot study. BMC Neurol. 2016; 16(1):77. PubMed
- Suwankesawong W, Saokaew S, Permsuwan U, et al. Characterization of hypersensitivity reactions reported among Andrographis paniculata users in Thailand using Health Product Vigilance Center (HPVC) database. BMC Complement Altern Med. 2014; 14:515. PubMed
- Ciampi E, Uribe-San-Martin R, Cárcamo C, et al. Efficacy of andrographolide in not active progressive multiple sclerosis: a prospective exploratory double-blind, parallel-group, randomized, placebo-controlled trial. BMC Neurol 2020;20(1):173. PubMed
- Worakunphanich W, Thavorncharoensap M, Youngkong S, Thadanipon K, Thakkinstian A. Safety of Andrographis paniculata: A systematic review and meta-analysis. Pharmacoepidemiol Drug Saf 2021;30(6):727-739.
- More SJ, Tandulwadkar SS, Balap AR, Lohidasan S, Sinnathambi A, Mahadik KR. Effect of Andrographis paniculata extract and Andrographolide on the pharmacokinetics of Aceclofenac and Celecoxib in rats. Futur J Pharm Sci. 2023;9(1):1. PubMed
- Sundhani E, Nugroho AE, Nurrochmad A, Puspitasari I, Amalia Prihati D, Lukitaningsih E. Pharmacokinetic Herb-Drug Interactions of Glipizide with Andrographis paniculata (Burm. f.) and Andrographolide in Normal and Diabetic Rats by Validated HPLC Method. M PubMed
- Shang YX, Shen C, Stub T, et al. Adverse Effects of Andrographolide Derivative Medications Compared to the Safe use of Herbal Preparations of Andrographis paniculata: Results of a Systematic Review and Meta-Analysis of Clinical Studies. Front Pharmacol 20 PubMed
Hyaluronic Acid 4 references
- Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
- U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
- Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
- Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC