Athlex Ginseng Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Athlex Ginseng against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Athlex Ginseng is a dietary supplement by Tonic Tinctures with 10 active ingredients. Its ingredients are commonly taken for low libido or sexual performance, erectile difficulties, general energy and fatigue.Based on those ingredients, 1,240 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Eleuthero, Cinnamon, Tienchi Notoginseng. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Athlex Ginseng by Tonic Tinctures
Ask about any prescription or over-the-counter medication and we check it for interactions with Athlex Ginseng by Tonic Tinctures — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Athlex Ginseng by Tonic Tinctures
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Athlex Ginseng contains 10 active ingredients. The main ones are Panax red Ginseng and Korean Red Ginseng, both traditional energy and vitality tonics; Eleuthero (Siberian ginseng), used as an adaptogen; Tienchi Notoginseng, traditionally taken for circulation and blood flow; Cassia cinnamon, a warming spice; Muira Puama; Catuaba; Eucommia; Pine Pollen; and Curculigo.
The liquid is made with water and alcohol as inactive ingredients.
Does it work?
Moderate evidence
The evidence for most ingredients in this blend is limited or not yet established in our data. Eleuthero is possibly effective for genital herpes, but insufficient evidence exists for chronic fatigue, osteoporosis, bipolar disorder, or familial Mediterranean fever.
Tienchi Notoginseng is possibly effective for angina, stroke, and intracranial hemorrhage, but possibly ineffective for heart attack. For sexual dysfunction and erectile dysfunction (Muira Puama), diabetes (cinnamon and eleuthero), and other conditions listed, the evidence is too sparse to rate.
This is a traditional tonic blend rather than one backed by strong clinical proof for any single condition.
How safe is it?
Well-documented data
Eleuthero is generally well tolerated short-term but long-term safety isn't well established. Adverse effects in trials include diarrhea, nausea, headache, and nervousness — the last one occurred in about 7 in 100 people taking it, and higher doses may increase anxiety or irritability.
Some people reported elevated blood pressure. Tienchi Notoginseng appears generally well tolerated but safety data are limited; common effects are dry mouth, nausea, insomnia, and nervousness.
Cassia cinnamon in food amounts is likely fine, but supplement doses high in coumarin — a compound in cinnamon — may harm the liver over time. A rash has been reported rarely.
Catuaba and Muira Puama have very limited human safety data. None of these ingredients should be used during pregnancy or while breastfeeding based on the available safety information.
Meds to double-check
Moderate interaction found
Check before starting if you take warfarin or other blood thinners (Moderate risk of increased bleeding from Tienchi Notoginseng and eleuthero); diabetes medications (Moderate additive blood-sugar-lowering effect from eleuthero and cinnamon); digoxin or other heart drugs (Moderate risk of increased digoxin levels); immunosuppressants; medications metabolized by liver enzymes (CYP1A2, CYP2C9, CYP2D6); aspirin; or drugs that could be harmed by liver damage. No interactions are documented for Panax red Ginseng, Eucommia, Pine Pollen, Curculigo, or Korean Red Ginseng in our data.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
This is a traditional herbal blend with multiple ingredients that interact with common medications — especially blood thinners, diabetes drugs, heart medications, and drugs your liver metabolizes. If you take any prescription medication, check it against the tool below before starting.
Talk to your pharmacist before using this product, particularly if you're on warfarin, aspirin, digoxin, diabetes medication, or immunosuppressants.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Athlex Ginseng, straight from the product label.
| Brand | Tonic Tinctures |
|---|---|
| Net contents | 2 Fluid Ounce(s); 60 mL |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2022 |
| DSLD ID | 259504 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Athlex Ginseng by Tonic Tinctures, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Catauba | 0 NP | -- |
| Panax red Ginseng | 0 NP | -- |
| Eleuthero | 0 NP | -- |
| Eucommia | 0 NP | -- |
| Pine Pollen | 0 NP | -- |
| Curculigo | 0 NP | -- |
| Muria Puama | 0 NP | -- |
| Korean Red Ginseng | 0 NP | -- |
| Tienchi Notoginseng | 0 NP | -- |
| Cinnamon | 0 NP | -- |
Other ingredients: Water, Distilled, Alcohol
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Artisan liquid extract 1 dropper is approximately equal to 1000 mgs
Gluten free, no hidden additives
Suggested/Recommended/Usage/Directions
Shake gently before use
Directions: Use as directed, 1-3 droppers 1-3 times a day. Use within 45 days of opening.
Precautions
Keep out of reach of children.
Discontinue use if unusual symptoms occur.
FDA Disclaimer Statement
Caution: These products are not intended to diagnose, treat, cure or prevent any disease. These statements have not been evaluated by the FDA
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Athlex Ginseng by Tonic Tinctures label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Athlex Ginseng by Tonic Tinctures
These are the 10 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Dropper(s) Dosage formLiquid Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Catauba
No knowninteractions
Catuaba is a Brazilian herbal bark long used as a traditional aphrodisiac and energy tonic, but there is very little reliable human research to show i...
Catauba monograph & interactionsPanax red Ginseng
Eleuthero
Interacts with1,140 drugs
Eleuthero is an herb traditionally used as an 'adaptogen' to fight fatigue, boost energy, and help the body handle stress. The scientific evidence beh...
Eleuthero monograph & interactionsEucommia
Pine Pollen
Curculigo
Muria Puama
No knowninteractions
Muira puama is a Brazilian plant traditionally used as an aphrodisiac and general tonic, often nicknamed 'potency wood.' Human research is very limite...
Muria Puama monograph & interactionsKorean Red Ginseng
Tienchi Notoginseng
Interacts with207 drugs
Panax notoginseng (sanqi or tienchi ginseng) is a traditional Chinese herb most often used to help with bleeding, bruising, and circulation. Human evi...
Tienchi Notoginseng monograph & interactionsCinnamon
Interacts with442 drugs
Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evi...
Cinnamon monograph & interactionsOther (inactive) ingredients: Water, Distilled, Alcohol. These complete the product’s ingredient list but are not active constituents.
Athlex Ginseng by Tonic Tinctures Drug Interactions
HelloPharmacist Interaction Report
Athlex Ginseng by Tonic Tinctures contains multiple ingredients with documented interactions affecting over 1,200 individual medications.
The most serious concern is Tienchi Notoginseng (also called Panax notoginseng), which carries a Moderate risk with warfarin (Coumadin) and other blood thinners — it may increase bleeding risk by raising warfarin levels.
Read the full breakdown — every affected drug type, severity by severity
Eleuthero has Moderate interactions with several medication types: drugs metabolized by your liver (CYP1A2 and CYP2C9 substrates), which it may slow down and increase to potentially unsafe levels; blood thinners and antiplatelet drugs, where it may raise bleeding risk; drugs for diabetes, where it may lower blood sugar too far; digoxin (a heart medication), which it may cause to accumulate; immunosuppressants, which it may interfere with; and a Minor interaction with CYP2D6 substrates (though human studies suggest this is less likely). Panax notoginseng also affects CYP1A2 substrates and caffeine, though it may decrease their levels rather than increase them, and it interacts with aspirin similarly to warfarin.
Cassia cinnamon has Moderate interactions with diabetes medications and hepatotoxic drugs (those that can damage the liver), where large doses may cause additive effects. We could not check Panax red Ginseng, Eucommia, Pine Pollen, Curculigo, or Korean Red Ginseng — no interaction data are on file for these ingredients.
Use the medication checker below to verify your exact prescriptions before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Athlex Ginseng?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Athlex Ginseng interact with 1,240 drugs. Click any drug to see the details.
3 of the 10 ingredients in Athlex Ginseng interact with drugs. Each result below shows which ingredient is responsible. Eleuthero Cinnamon Tienchi Notoginseng
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Athlex Ginseng — through 2 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + 6-mercaptopurine interactionEleutheroImmunosuppressants Moderate
Interaction Summary
Theoretically, eleuthero might interfere with immunosuppressive drugs because of its immunostimulant activity.
Read the full Eleuthero + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Athlex Ginseng — through 1 ingredient. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Athlex Ginseng — through 1 ingredient. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Athlex Ginseng — through 1 ingredient. Tap an ingredient for the detail:
EleutheroAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, eleuthero may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Eleuthero + Abciximab interactionAbiraterone
How Abiraterone interacts with Athlex Ginseng — through 2 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Abiraterone interactionEleutheroCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
Read the full Eleuthero + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Athlex Ginseng — through 2 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Abiraterone Acetate interactionEleutheroCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
Read the full Eleuthero + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Athlex Ginseng — through 1 ingredient. Tap an ingredient for the detail:
EleutheroImmunosuppressants, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, eleuthero might interfere with immunosuppressive drugs because of its immunostimulant activity.
Read the full Eleuthero + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Athlex Ginseng — through 1 ingredient. Tap an ingredient for the detail:
EleutheroP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of P-glycoprotein substrates.
Read the full Eleuthero + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Athlex Ginseng — through 2 ingredients. Tap an ingredient for the detail:
EleutheroAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eleuthero might have additive effects when used with antidiabetes drugs.
Read the full Eleuthero + Acarbose interactionCinnamonHepatotoxic Drugs, Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Athlex Ginseng — through 1 ingredient. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Athlex Ginseng — through 1 ingredient. Tap an ingredient for the detail:
EleutheroAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, eleuthero may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Eleuthero + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
Tienchi NotoginsengCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Tienchi Notoginseng + Acetaminophen interactionEleutheroCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleuthero + Acetaminophen interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
Tienchi NotoginsengCytochrome P450 1a2 (cyp1a2) Substrates, Aspirin Moderate
Interaction Summary
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Tienchi Notoginseng + Acetaminophen, Aspirin interactionEleutheroAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eleuthero may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Eleuthero + Acetaminophen, Aspirin interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
Tienchi NotoginsengCaffeine, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, taking Panax notoginseng may decrease the levels and clinical effects of caffeine.
Read the full Tienchi Notoginseng + Acetaminophen, Aspirin, Caffeine interactionEleutheroCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleuthero + Acetaminophen, Aspirin, Caffeine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
Tienchi NotoginsengCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Tienchi Notoginseng + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionEleutheroCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleuthero + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
Tienchi NotoginsengCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Tienchi Notoginseng + Acetaminophen, Butalbital interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Butalbital interactionEleutheroCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleuthero + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
Tienchi NotoginsengCaffeine, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking Panax notoginseng may decrease the levels and clinical effects of caffeine.
Read the full Tienchi Notoginseng + Acetaminophen, Butalbital, Caffeine interactionEleutheroCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleuthero + Acetaminophen, Butalbital, Caffeine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
Tienchi NotoginsengCytochrome P450 1a2 (cyp1a2) Substrates, Caffeine Moderate
Interaction Summary
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Tienchi Notoginseng + Acetaminophen, Butalbital, Caffeine, Codeine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Butalbital, Caffeine, Codeine interactionEleutheroCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleuthero + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
EleutheroCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP2D6.
Read the full Eleuthero + Acetaminophen, Butalbital, Codeine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Butalbital, Codeine interactionTienchi NotoginsengCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Tienchi Notoginseng + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
EleutheroCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleuthero + Acetaminophen, Butalbital, Codeine Phosphate interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Butalbital, Codeine Phosphate interactionTienchi NotoginsengCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Tienchi Notoginseng + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
Tienchi NotoginsengCytochrome P450 1a2 (cyp1a2) Substrates, Caffeine Moderate
Interaction Summary
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Tienchi Notoginseng + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionEleutheroCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleuthero + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
EleutheroCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
Read the full Eleuthero + Acetaminophen, Caffeine, Codeine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Codeine interactionTienchi NotoginsengCytochrome P450 1a2 (cyp1a2) Substrates, Caffeine Moderate
Interaction Summary
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Tienchi Notoginseng + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
Tienchi NotoginsengCaffeine, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking Panax notoginseng may decrease the levels and clinical effects of caffeine.
Read the full Tienchi Notoginseng + Acetaminophen, Caffeine, Codeine, Salicylamide interactionEleutheroCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleuthero + Acetaminophen, Caffeine, Codeine, Salicylamide interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
Tienchi NotoginsengCytochrome P450 1a2 (cyp1a2) Substrates, Caffeine Moderate
Interaction Summary
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Tienchi Notoginseng + Acetaminophen, Caffeine, Dihydrocodeine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Dihydrocodeine interactionEleutheroCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleuthero + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
EleutheroCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
Read the full Eleuthero + Acetaminophen, Caffeine, Isometheptene interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Isometheptene interactionTienchi NotoginsengCytochrome P450 1a2 (cyp1a2) Substrates, Caffeine Moderate
Interaction Summary
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Tienchi Notoginseng + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
Tienchi NotoginsengCaffeine, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking Panax notoginseng may decrease the levels and clinical effects of caffeine.
Read the full Tienchi Notoginseng + Acetaminophen, Caffeine, Pyrilamine interactionEleutheroCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleuthero + Acetaminophen, Caffeine, Pyrilamine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
Tienchi NotoginsengCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Tienchi Notoginseng + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionEleutheroCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleuthero + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
EleutheroCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP2D6.
Read the full Eleuthero + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionTienchi NotoginsengCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Tienchi Notoginseng + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
EleutheroCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleuthero + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionTienchi NotoginsengCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Tienchi Notoginseng + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Athlex Ginseng — through 3 ingredients. Tap an ingredient for the detail:
Tienchi NotoginsengCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Tienchi Notoginseng + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionEleutheroCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
Read the full Eleuthero + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Athlex Ginseng with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Eleuthero
Anticoagulant/Antiplatelet Drugs
Theoretically, eleuthero may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research shows that a constituent of eleuthero, dihydroxybenzoic acid, appears to inhibit platelet aggregation. Concomitant use with anticoagulant or antiplatelet drugs might increase the risk of bleeding. This effect has not been reported in humans.
Antidiabetes Drugs
Theoretically, eleuthero might have additive effects when used with antidiabetes drugs.
Animal research suggests that certain constituents of eleuthero have hypoglycemic activity in both healthy and diabetic animals. A small study in adults with type 2 diabetes also shows that taking eleuthero for 3 months can lower blood glucose levels. However, one very small study in healthy individuals shows that taking powdered eleuthero 3 grams, 40 minutes prior to a 75-gram oral glucose tolerance test, significantly increases postprandial blood glucose levels when compared with placebo. These contradictory findings might be due to patient-specific variability and variability in active ingredient ratios.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
In vitro and animal research suggest that standardized extracts of eleuthero inhibit CYP1A2. This effect has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, eleuthero might increase levels of drugs metabolized by CYP2C9.
In vitro and animal research suggest that standardized extracts of eleuthero might inhibit CYP2C9. This effect has not been reported in humans.
Digoxin (Lanoxin)
Eleuthero might increase serum digoxin levels and increase the risk of side effects.
In one case report, a 74-year-old male who was stabilized on digoxin presented with an elevated serum digoxin level after starting an eleuthero supplement, without symptoms of toxicity. After stopping the supplement, serum digoxin levels returned to normal. It is not clear whether this was due to a pharmacokinetic interaction or to interference with the digoxin assay. Although the product was found to be free of digoxin and digitoxin, it was not tested for other contaminants.
Immunosuppressants
Theoretically, eleuthero might interfere with immunosuppressive drugs because of its immunostimulant activity.
Animal and in vitro research shows that eleuthero extracts have immunomodulatory effects, including increasing cellular and humoral activity.
P-Glycoprotein Substrates
Theoretically, eleuthero might increase levels of P-glycoprotein substrates.
In vitro research suggests that eleuthero can inhibit the multi-drug transporter protein, P-glycoprotein. However, it is too soon to tell if this is clinically important. This interaction has not been reported in humans.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, eleuthero might increase levels of drugs metabolized by CYP2D6.
In vitro and animal research suggest that standardized extracts of eleuthero might inhibit CYP2D6. However, research in healthy human volunteers has found that taking eleuthero 485 mg twice daily for 14 days does not inhibit CYP2D6 drug metabolism.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
In vitro and animal research suggest that standardized extracts of eleuthero might inhibit CYP3A4. However, research in healthy human volunteers has found that taking eleuthero 485 mg twice daily for 14 days does not inhibit CYP3A4 drug metabolism.
Organic Anion-Transporting Polypeptide Substrates (Oatp)
Theoretically, eleuthero might decrease levels of drugs metabolized by OATP.
In vitro research suggests that eleuthero inhibits OATP2B1, which might reduce the bioavailability of oral drugs that are substrates of OATP2B1. Due to the weak inhibitory effect identified in this study, this interaction is not likely to be clinically significant.
Cinnamon
Antidiabetes Drugs
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.
Hepatotoxic Drugs
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.
Tienchi Notoginseng
Aspirin
Theoretically, taking Panax notoginseng concomitantly with aspirin may increase the risk of adverse effects from both products.
Animal research shows that taking Panax notoginseng extract with aspirin increases blood levels of salicylic acid by approximately 50% and blood levels of Panax notoginseng by 75% to 196%. This effect may be due to increased absorption of both products.
Caffeine
Theoretically, taking Panax notoginseng may decrease the levels and clinical effects of caffeine.
Animal research shows that administering Panax notoginseng intravenously for 7 days before intraperitoneal injection of caffeine can decrease maximal blood levels of caffeine by 37%. This interaction is attributed to the ability of Panax notoginseng to increase the activity of cytochrome P450 1A2 (CYP1A2) enzymes.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Animal research shows that administering Panax notoginseng intravenously for 7 days before intraperitoneal injection of caffeine can decrease maximal blood levels of caffeine by 37%. This interaction was attributed to the ability of Panax notoginseng to increase the activity of CYP1A2.
Warfarin (Coumadin)
Theoretically, taking Panax notoginseng concomitantly with warfarin may increase the risk of bleeding.
Animal research shows that taking Panax notoginseng concomitantly with warfarin increases plasma warfarin levels, prothrombin time, and international normalized ratio when compared with control. In vitro research also suggests that Panax notoginseng may downregulate expression of cytochrome P450 3A4 enzymes, which may affect warfarin metabolism.
Brand information
Manufacturer and brand details for Athlex Ginseng, from the product label.
Tonic Tinctures
See all Tonic Tinctures products- Name
- Tonic Apothecary
- Web Address
- www.tonictinctures.com
Athlex Ginseng by Tonic Tinctures: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Athlex Ginseng’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Catuaba
Catuaba is a Brazilian herbal bark long used as a traditional aphrodisiac and energy tonic, but there is very little reliable human research to show it works for any health condition. Qualit...
Read the full Catuaba monograph → Herb & supplement monographEleuthero
Interacts with 1,140 drugsEleuthero is an herb traditionally used as an 'adaptogen' to fight fatigue, boost energy, and help the body handle stress. The scientific evidence behind these uses is limited and mixed, so...
Read the full Eleuthero monograph → Herb & supplement monographMuira Puama
Muira puama is a Brazilian plant traditionally used as an aphrodisiac and general tonic, often nicknamed 'potency wood.' Human research is very limited, so its benefits are not well proven,...
Read the full Muira Puama monograph → Herb & supplement monographPanax Notoginseng
Interacts with 207 drugsPanax notoginseng (sanqi or tienchi ginseng) is a traditional Chinese herb most often used to help with bleeding, bruising, and circulation. Human evidence for these uses is limited and most...
Read the full Panax Notoginseng monograph → Herb & supplement monographCassia Cinnamon
Interacts with 442 drugsCassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evidence for its health benefits is mixed a...
Read the full Cassia Cinnamon monograph →Sources & How We Checked
Athlex Ginseng's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 61 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Eleuthero 24 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- McRae S. Elevated serum digoxin levels in a patient taking digoxin and Siberian ginseng. CMAJ 1996;155:293-5.
- Awang DVC. Siberian ginseng toxicity may be case of mistaken identity (letter). CMAJ 1996;155:1237.
- Mills S, Bone K. Principles and Practice of Phytotherapy. London: Churchill Livingstone, 2000.
- Harkey MR, Henderson GL, Zhou L, et al. Effects of Siberian ginseng (Eleutherococcus senticosus) on c-DNA-expressed P450 drug metabolizing enzymes. Alt Ther 2001;7:S14.
- Hikino H, Takahashi M, Otake K, Konno C. Isolation and hypoglycemic activity of eleutherans A, B, C, D, E, F, and G: glycans of Eleutherococcus senticosus roots. J Nat Prod 1986;49:293-7. PubMed
- Yun-Choi HS, Kim JH, Lee JR. Potential inhibitors of platelet aggregation from plant sources, III. J Nat Prod 1987;50:1059-64. PubMed
- Donovan JL, DeVane CL, Chavin KD, et al. Siberian Ginseng (Eleutheroccus senticosus) Effects on CYP2D6 and CYP3A4 Activity in Normal Volunteers. Drug Metab Dispos 2003;31:519-22.. PubMed
- Hartz AJ, Bentler S, Noyes R et al. Randomized controlled trial of Siberian ginseng for chronic fatigue. Psychol Med 2004;34:51-61. PubMed
- Sievenpiper JL, Arnason JT, Leiter LA, Vuksan V. Decreasing, null and increasing effects of eight popular types of ginseng on acute postprandial glycemic indices in healthy humans: the role of ginsenosides. J Am Coll Nutr 2004;23:248-58. PubMed
- Dasgupta A, Wu S, Actor J, et al. Effect of Asian and Siberian ginseng on serum digoxin measurement by five digoxin immunoassays. Significant variation in digoxin-like immunoreactivity among commercial ginsengs. Am J Clin Pathol 2003;119:298-303. DOI
- Takahashi T, Kaku T, Sato T, et al. Effects of Acanthopanax senticosus HARMS extract on drug transport in human intestinal cell line Caco-2. J Nat Med. 2010;64(1):55-62. PubMed
- Fuchikami H, Satoh H, Tsujimoto M, Ohdo S, Ohtani H, Sawada Y. Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos 2006;34:577-82. PubMed
- Friedman, J. A., Taylor, S. A., McDermott, W., and Alikhani, P. Multifocal and recurrent subarachnoid hemorrhage due to an herbal supplement containing natural coumarins. Neurocrit.Care 2007;7(1):76-80. PubMed
- Molokovskii, D. S., Davydov, V. V., and Tiulenev, V. V. [The action of adaptogenic plant preparations in experimental alloxan diabetes]. Probl.Endokrinol.(Mosk) 1989;35(6):82-87.
- Schmolz, M. W., Sacher, F., and Aicher, B. The synthesis of Rantes, G-CSF, IL-4, IL-5, IL-6, IL-12 and IL-13 in human whole-blood cultures is modulated by an extract from Eleutherococcus senticosus L. roots. Phytother.Res 2001;15(3):268-270.
- Huang, D. B., Ran, R. Z., and Yu, Z. F. [Effect of Acanthopanax senticosus injection on the activities of human tumor necrosis factor and natural killer cell in blood in the patients with lung cancer]. Zhongguo Zhong.Yao Za Zhi. 2005;30(8):621-624.
- Niu, H. S., Hsu, F. L., Liu, I. M., and Cheng, J. T. Increase of beta-endorphin secretion by syringin, an active principle of Eleutherococcus senticosus, to produce antihyperglycemic action in type 1-like diabetic rats. Horm.Metab Res 2007;39(12):894-898
- Watanabe, K., Kamata, K., Sato, J., and Takahashi, T. Fundamental studies on the inhibitory action of Acanthopanax senticosus Harms on glucose absorption. J Ethnopharmacol. 10-28-2010;132(1):193-199. PubMed
- Bazaz'ian, G. G., Liapina, L. A., Pastorova, V. E., and Zvereva, E. G. [Effect of Eleutherococcus on the functional status of the anticoagulation system in older animals]. Fiziol.Zh.SSSR Im I.M.Sechenova 1987;73(10):1390-1395.
- Kaloeva, Z. D. [Effect of the glycosides of Eleutherococcus senticosus on the hemodynamic indices of children with hypotensive states]. Farmakol.Toksikol. 1986;49(5):73.
- Martinez, B. and Staba, E. J. The physiological effects of Aralia, Panax and Eleutherococcus on exercised rats. Jpn J Pharmacol 1984;35(2):79-85. DOI
- Medon, P. J., Thompson, E. B., and Farnsworth, N. R. Hypoglycemic effect and toxicity of Eleutherococcus senticosus following acute and chronic administration in mice. Zhongguo Yao Li Xue.Bao. 1981;2(4):281-285.
- Freye E, GLeske J. Siberian ginseng results in beneficial effects on glucose metabolism in diabetes type 2 patients: a double blind placebo-controlled study in comparison to panax ginseng. Int J Clin Nutr. 2013;1(1):11-17.
Muira Puama 2 references
- Waynberg, J. and Brewer, S. Effects of Herbal vX on libido and sexual activity in premenopausal and postmenopausal women. Adv Ther 2000;17(5):255-262. PubMed
- Nguyen S, Rajfer J, Shaheen M. Safety and efficacy of daily Revactin in men with erectile dysfunction: a 3-month pilot study. Transl Androl Urol. 2018;7(2):266-73. PubMed
Panax Notoginseng 15 references
- Huang KC. The Pharmacology of Chinese Herbs. 2nd ed. New York, NY: CRC Press, LLC 1999:101-102.
- Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine Materia Medica. Seattle, WA: Eastland Press, 1996:359-60.
- Chan LY, Chiu PY, Lau TK. An in-vitro study of ginsenoside Rb(1)-induced teratogenicity using a whole rat embryo culture model. Hum Reprod 2003;18:2166-8..
- Du XF, Yin XP, Zhang GL, Shi HJ, Shao MH. Interstitial granulomatous drug reaction to a Chinese herb extract. Eur J Dermatol. 2012 May-Jun;22(3):419-20. PubMed
- Liu R, Qin M, Hang P, Liu Y, Zhang Z, Liu G. Effects of Panax notoginseng saponins on the activities of CYP1A2, CYP2C9, CYP2D6 and CYP3A4 in rats in vivo. Phytother Res. 2012 Aug;26(8):1113-8.
- Shang Q, Xu H, Liu Z, Chen K, Liu J. Oral Panax notoginseng Preparation for Coronary Heart Disease: A Systematic Review of Randomized Controlled Trials. Evid Based Complement Alternat Med. 2013;2013:940125.
- Tian Z, Pang H, Du S, Lu Y, Zhang L, Wu H, Guo S, Wang M, Zhang Q. Effect of Panax notoginseng saponins on the pharmacokinetics of aspirin in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Jan 1;1040:136-143. PubMed
- Xu D, Huang P, Yu Z, Xing DH, Ouyang S, Xing G. Efficacy and Safety of Panax notoginseng Saponin Therapy for Acute Intracerebral Hemorrhage, Meta-Analysis, and Mini Review of Potential Mechanisms of Action. Front Neurol. 2015 Jan 7;5:274. PubMed
- Yang X, Xiong X, Wang J. Sanqi panax notoginseng injection for angina pectoris. Evid Based Complement Alternat Med. 2014;2014:963208. PubMed
- Yin Z, Ma L, Xu J, Xia J, Luo D. Pustular drug eruption due to Panax notoginseng saponins. Drug Des Devel Ther. 2014 Jul 16;8:957-61. PubMed
- Song H, Wang P, Liu J, Wang C. Panax notoginseng Preparations for Unstable Angina Pectoris: A Systematic Review and Meta-Analysis. Phytother Res. 2017 Jun 20.
- Tian Z, Pang H, Zhang Q, et al. Effect of aspirin on the pharmacokinetics and absorption of panax notoginsengsaponins. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jan 2;1074-75.
- Li C, Xu T, Zhou P, et al. Post-marketing safety surveillance and re-evaluation of Xueshuantong injection. BMC Complement Altern Med. 2018;18(1):277. PubMed
- Liu L, Shen XJ, Xue LJ, Yao SK, Zhu JY. Submucosal hematoma with a wide range of lesions, severe condition and atypical clinical symptoms: A case report. World J Clin Cases 2021;9(20):5683-5688. PubMed
- Qian J, Chen W, Wu J, et al. Effects and Mechanism of Action of Panax notoginseng Saponins on the Pharmacokinetics of Warfarin. Eur J Drug Metab Pharmacokinet 2022;47(3):331-342. PubMed
Cassia Cinnamon 20 references
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
- De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
- Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
- Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
- Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
- Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
- Akilen, R., Tsiami, A., Devendra, D., and Robinson, N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet.Med. 2010; PubMed
- Lu T, Sheng H Wu J Cheng Y Zhu J Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408-412. PubMed
- Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
- Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007;30(4):813-6. PubMed
- Stoecker BR, Zhan Z, Luo R, et al. Cinnamon extract lowers blood glucose in hyperglycemic subjects. FASEB J. 2010;22:722.1 (Abstract only). DOI
- Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
- Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
- Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
- Wickenberg J, Lindstedt S, Nilsson J, Hlebowicz J. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutr J 2014 Sep 24;13:96. PubMed
- Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
- Shekarchizadeh-Esfahani P, Heydarpour F, Izadi F, Jalili C. The effect of cinnamon supplementation on liver enzymes in adults: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2021;58:102699. PubMed
- Bernaola J, Valverde-Monge M, Otal-Buesa M, Cullen D, Heras-Mendaza F. Cinnamon allergic contact cheilitis. Contact Dermatitis 2023;88(5):418-419. PubMed
- Patel K, Howard M, Tate B. Cheilitis caused by allergic contact dermatitis to cinnamon in chai tea: A case report. Contact Dermatitis 2023;88(3):239-240. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC