Bacopa 100 mg Ingredients & Drug Interactions
by Solaray
What is this page for?
First and foremost: checking Bacopa 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Bacopa 100 mg is a dietary supplement by Solaray with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, anxiety and stress, adhd symptoms.Based on those ingredients, 930 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bacopa Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Bacopa 100 mg by Solaray
Ask about any prescription or over-the-counter medication and we check it for interactions with Bacopa 100 mg by Solaray — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Bacopa 100 mg by Solaray
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 0 of its 2 active ingredients.
- “Bacopa Leaf Extract” is listed as a grouped ingredient — the label gives one combined amount (100 mg) without saying how much of each component you get.
- “Bacosides” is listed as a grouped ingredient — the label gives one combined amount (20 mg) without saying how much of each component you get.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Bacopa 100 mg, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Bacopa 100 mg by Solaray, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Bacopa Leaf Extract | 100 mg | -- |
| Bacosides | 20 mg | -- |
| Bacoside A | 0 NP | -- |
| Bacoside B | 0 NP | -- |
Other ingredients: Cellulose, Rice Bran Extract Blend, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Solaray Est. 1973 A Brighter Way 1973
Formulation
Cognitive support
Formula
20% Bacosides A & B
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Lab Verified
General Statements
Since 1973, we've scoured the globe for the highest quality ingredients, connecting you with the most efficacious supplements that help you live brighter & embrace the moments that matter most.
100% PCR bottles
Vital extracts
Precautions
Warning: Do not use if safety seal is broken or missing. Keep your licensed health care practitioner informed when using this product.
Keep out of reach of children.
Directions: Use only as directed.
Suggested/Recommended/Usage/Directions
Directions: Use only as directed. Take 1 vegcap daily with a meal or glass of water.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Bacopa 100 mg by Solaray label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Bacopa 100 mg by Solaray
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 VegCap(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Bacopa Leaf Extract
Interacts with930 drugs
Bacopa is an Ayurvedic herb most often used for memory and thinking. Some small studies suggest it may modestly help memory when taken regularly for s...
Bacopa Leaf Extract monograph & interactions- › Bacosides
Other (inactive) ingredients: Cellulose, Rice Bran Extract Blend, Silica. These complete the product’s ingredient list but are not active constituents.
Bacopa 100 mg by Solaray Drug Interactions
Bacopa 100 mg contains a single active ingredient, and it has known interactions with 930 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Bacopa 100 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Bacopa 100 mg interact with 930 drugs. Click any drug to see the details.
1 of the 1 ingredient in Bacopa 100 mg interact with drugs. Each result below shows which ingredient is responsible. Bacopa Leaf Extract
Desiccated Thyroid ExtractWesthroid, WP Thyroid
How Desiccated Thyroid Extract interacts with Bacopa 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractThyroid Hormone Minor
Interaction Summary
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Read the full Bacopa Leaf Extract + Desiccated Thyroid Extract interactionDesiccated Thyroid Extract (prescription Drug)Nature-Throid, Thyrar
How Desiccated Thyroid Extract (prescription Drug) interacts with Bacopa 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractThyroid Hormone Minor
Interaction Summary
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Read the full Bacopa Leaf Extract + Desiccated Thyroid Extract (prescription Drug) interactionDextrothyroxineCholoxin
How Dextrothyroxine interacts with Bacopa 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractThyroid Hormone Minor
Interaction Summary
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Read the full Bacopa Leaf Extract + Dextrothyroxine interactionHuman Chorionic Gonadotropin (hcg)Pregnyl
How Human Chorionic Gonadotropin (hcg) interacts with Bacopa 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractThyroid Hormone Minor
Interaction Summary
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Read the full Bacopa Leaf Extract + Human Chorionic Gonadotropin (hcg) interactionLevothyroxineEltroxin, Estre, Euthyrox, Levo-T, Levolet, Levothroid +5 more
How Levothyroxine interacts with Bacopa 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractThyroid Hormone Minor
Interaction Summary
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Read the full Bacopa Leaf Extract + Levothyroxine interactionLevothyroxine SodiumErmez, Thyquidity, Tirosint-Sol
How Levothyroxine Sodium interacts with Bacopa 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractThyroid Hormone Minor
Interaction Summary
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Read the full Bacopa Leaf Extract + Levothyroxine Sodium interactionLevothyroxine, LiothyronineArmour Thyroid
How Levothyroxine, Liothyronine interacts with Bacopa 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractThyroid Hormone Minor
Interaction Summary
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Read the full Bacopa Leaf Extract + Levothyroxine, Liothyronine interactionLiothyronineCytomel
How Liothyronine interacts with Bacopa 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractThyroid Hormone Minor
Interaction Summary
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Read the full Bacopa Leaf Extract + Liothyronine interactionLiotrixEuthroid 1, Euthroid 1/2, Euthroid 3
How Liotrix interacts with Bacopa 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractThyroid Hormone Minor
Interaction Summary
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Read the full Bacopa Leaf Extract + Liotrix interactionLiotrix, T4/t3Euthroid 2
How Liotrix, T4/t3 interacts with Bacopa 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractThyroid Hormone Minor
Interaction Summary
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Read the full Bacopa Leaf Extract + Liotrix, T4/t3 interactionMenotropinsMenopur, Repronex
How Menotropins interacts with Bacopa 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractThyroid Hormone Minor
Interaction Summary
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Read the full Bacopa Leaf Extract + Menotropins interactionThyroglobulinProloid
How Thyroglobulin interacts with Bacopa 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractThyroid Hormone Minor
Interaction Summary
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Read the full Bacopa Leaf Extract + Thyroglobulin interactionThyroid HormoneEtwon
How Thyroid Hormone interacts with Bacopa 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Bacopa Leaf ExtractThyroid Hormone Minor
Interaction Summary
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Read the full Bacopa Leaf Extract + Thyroid Hormone interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Bacopa 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Bacopa Leaf Extract
Anticholinergic Drugs
Theoretically, concurrent use might decrease the effectiveness of both agents.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels, which could counteract the effects of anticholinergic drugs. Similarly, anticholinergic drugs might counteract the cholinergic effects of bacopa.
Cevimeline (Evoxac)
Theoretically, bacopa might increase the effects and adverse effects of cevimeline.
In one case, a 58-year-old female taking cevimeline long-term for Sjogren syndrome experienced hyperhidrosis, malaise, nausea, and tachycardia shortly after taking a single dose of bacopa. Symptoms resolved after two days. Cevimeline is metabolized by cytochrome P450 (CYP) 2D6 and CYP3A4, and researchers theorize that bacopa may have inhibited these isoenzymes. However, it is unclear if bacopa causes clinically significant inhibition of either CYP2D6 or CYP3A4.
Cholinergic Drugs
Theoretically, concurrent use of bacopa with other cholinergic drugs might have additive effects.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels. Theoretically, this could result in additive cholinergic effects when used with cholinergic drugs.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Research on the effects of bacopa extracts on CYP1A2 enzymes is conflicting. Some in vitro evidence shows that bacopa extract can moderately and non-competitively inhibit CYP1A2, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP2C19 substrates.
In vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C19 enzymes. It is not known whether this is clinically significant.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP2C9 substrates.
Research on the effect of bacopa extracts on CYP2C9 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C9, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Research on the effects of bacopa extracts on CYP3A4 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and competitively inhibit CYP3A4, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.
Thyroid Hormone
Theoretically, bacopa might have additive effects when used with thyroid hormone.
Animal research suggests that bacopa increases thyroxine (T4) levels in mice by about 40%.
Brand information
Manufacturer and brand details for Bacopa 100 mg, from the product label.
Bacopa 100 mg by Solaray: Common Questions
Does Bacopa 100 mg by Solaray interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Bacopa 100 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Bacopa 100 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Bacopa 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bacopa 12 references
- Stough C, Lloyd J, Clarke J, et al. The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacology 2001;156:481-4..
- Yadav SK, Jain AK, Tripathi SN, Gupta JP. Irritable bowel syndrome: therapeutic evaluation of indigenous drugs. Indian J Med Res 1989;90:496-503..
- Morgan A, Stevens J. Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial. J Altern Complement Med 2010;16:753-9.
- Kar, A., Panda, S., and Bharti, S. Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice. J Ethnopharmacol. 2002;81(2):281-285. PubMed
- Mukherjee, G. D. and Dey, C. D. Clinical trial on Brahmi. I. J.Exp.Med.Sci. 1966;10(1):5-11.
- Kar A, Pandit S, Mukherjee K, Bahadur S, Mukherjee PK. Safety assessment of selected medicinal food plants used in Ayurveda through CYP450 enzyme inhibition study. J Sci Food Agric 2017;97(1):333-40. doi: 10.1002/jsfa.7739. PubMed
- Kongkeaw C, Dilokthornsakul P, Thanarangsarit P, et al. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol 2014;151(1):528-35. PubMed
- Ramasamy S, Kiew LV, Chung LY. Inhibition of human cytochrome P450 enzymes by Bacopa monnieri standardized extract and constituents. Molecules 2014;19(2):2588-601. PubMed
- Prabhakar S, Vishnu VY, Modi M, et al. Efficacy of Bacopa monnieri (Brahmi) and donepezil in Alzheimer's disease and mild cognitive impairment: a randomized double-blind parallel phase 2b study. Ann Indian Acad Neurol 2020;23(6):767-73. PubMed
- Acquarulo B, Tandon P, Macica CM. Suspected cholinergic toxicity due to cevimeline hydrochloride and Bacopa monnieri interaction: a case report. J Med Case Rep 2022;16(1):253. PubMed
- Keegan AP, Stough C, Paris D, et al. Bacopa monnieri supplementation has no effect on serum brain-derived neurotrophic factor levels but beneficially modulates nuclear factor kappa B and cyclic AMP response element-binding protein levels in healthy elderl
- Yaworski AM, Blyumin M, Chang T, Mammen AL, Greene M. Necrotizing myopathy with elevated anti-HMGCR antibodies following exposure to the supplement Bacopa. Muscle Nerve 2023;67(2):E1-E3.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC