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Dietary supplement

Bean & Vegetable Gas Relief Ingredients & Drug Interactions

by ProCaps Laboratories

Bean & Vegetable Gas Relief label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bean & Vegetable Gas Relief against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bean & Vegetable Gas Relief is a dietary supplement by ProCaps Laboratories with 2 active ingredients. Its ingredients are commonly taken for source of physostigmine (a prescription drug ingredient), historically used in 'trial by ordeal' rituals, traditional pain relief and anti-inflammatory uses.Based on those ingredients, 333 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Legume Enzyme Complex. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Bean & Vegetable Gas Relief by ProCaps Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Bean & Vegetable Gas Relief by ProCaps Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Bean & Vegetable Gas Relief by ProCaps Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 7 active ingredients.
  • “Legume Enzyme Complex” is a proprietary blend — the label gives one combined amount (270 mg) without saying how much of each component you get.

This product contains 7 active ingredients, most of them enzymes designed to help break down carbohydrates and fiber in beans and vegetables. Papain (from papaya) and bromelain (from pineapple) are protein-digesting enzymes.

The others — amylase, cellulase, invertase, hemicellulase, and alpha-galactosidase — are specialized carbohydrate enzymes that target different types of plant sugars and fiber. The capsule itself is made from gelatin.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support digestion of gas-causing foods.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for these ingredients isn't established in the data we hold. Papain and bromelain both have effectiveness ratings listed as insufficient evidence for the conditions studied — cancer, dental health, muscle soreness, nerve problems, and others.

For the gas-relief purpose this product is marketed for, we don't have effectiveness data in our monographs.

The evidence, ingredient by ingredient Calabar Bean Papain Bromelain

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Papain is generally tolerated as a food, but supplement doses may irritate your digestive tract or trigger allergic reactions in sensitive people — symptoms can include itchy eyes, runny nose, sneezing, stomach cramps, or diarrhea. High doses are unsafe and can rarely cause severe stomach inflammation or esophageal damage.

Bromelain is generally well tolerated short-term with digestive side effects like diarrhea, gas, and upset stomach most common, though it may also cause allergic reactions in sensitive individuals. During pregnancy, concentrated papain and unripe papaya products are best avoided due to safety concerns.

Bromelain should also be avoided in pregnancy because there isn't enough safety data. For breastfeeding, there isn't enough reliable information on papain to recommend it, and bromelain safety while nursing is unknown — talk with your doctor or pharmacist before using this product if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Calabar Bean Papain Bromelain

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Papain, Bromelain.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 141 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take warfarin (Coumadin) or other blood thinners and antiplatelet drugs — papain and bromelain both carry Moderate-severity risks. If you're on tetracycline antibiotics, bromelain may theoretically raise their levels (Minor severity).

Use the checker on this page to look up your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with gas from beans and vegetables, but we don't have effectiveness data in our records. If you take warfarin or other blood thinners or antiplatelet drugs, check with your pharmacist first — papain and bromelain both carry moderate interaction risks.

Pregnant or nursing women should talk to their doctor or pharmacist before starting it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bean & Vegetable Gas Relief, straight from the product label.

Brand ProCaps Laboratories
Barcode (UPC) 788684
Net contents 240 Easy-To-Swallow Capsule(s)
Market status On market
Date entered into DSLD Dec 21, 2024
DSLD ID 320060
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bean & Vegetable Gas Relief by ProCaps Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
240
UPC/BARCODE
788684
IngredientAmount% DV
Amylase0 NP--
Papain0 NP--
Bromelain0 NP--
Cellulase0 NP--
Invertase0 NP--
Hemicellulase0 NP--
Alpha-Galactosidase50 mg--
Legume Enzyme Complex270 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use Consume one or more capsules with meals based upon the "gas producing" content of those foods or as recommended by your physician.

Precautions

This product is not intended to treat any health condition.

General Statements

For questions about the use of this product call 800.332.7799. Andrew Lessman, Founder Questions? Reorder? www.HSN.com 800.944.9999 www.QVC.com 800.345.1515

Formulation

For over 40 years Unsurpassed purity, quality and efficacy 100% Solar production/ Zero carbon footprint 100% Solar

Andrew Lessman's Bean and Vegetable Gas Relief is a mild, natural, food supplement designed to gently and effectively support and enhance your body's natural digestion of gas-causing foods. Sadly, many of the healthiest foods, such as beans, cruciferous vegetables, fruits, nuts, seeds, grains and soy, contain molecules that can be difficult for the body to digest, causing gas, bloating and discomfort. The resulting gas and GI discomfort discourages us from eating these otherwise healthy foods. Scientists have identified the sources of gas in these foods and the digestive enzymes in Bean and Vegetable Gas Relief contains a unique blend of enzymes to target and break down these offending, gas-producing molecules thereby reducing or eliminating the gas, bloating and discomfort. Most of us occasionally experience issues enjoying some of nature's healthiest and most delicious foods, but the powerful natural enzymes in Bean and Vegetable Gas Relief are designed to return the enjoyment of these healthy foods without embarrassment or discomfort.

Contains not additives or common allergens

Contains No milk, soy, yeast, wheat, gluten, sodium, salt, sugar, fat, cholesterol, color, preservative, common allergens, genetically modified (GMO) ingredients or manufacturing additives.

Formula

Natural Enzyme Complex Beans/Nuts/Seeds/Legumes/Fruit/Cruciferous Vegetables/Whole Grains

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated the by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bean & Vegetable Gas Relief by ProCaps Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bean & Vegetable Gas Relief label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bean & Vegetable Gas Relief by ProCaps Laboratories

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container240 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Alpha-Galactosidase

50 mg per serving

Legume Enzyme Complex

Interacts with
195 drugs
270 mg per serving

Calabar bean is a highly poisonous West African seed that contains physostigmine, a powerful cholinesterase inhibitor. It is not a safe dietary supple...

Legume Enzyme Complex monograph & interactions
  • › Amylase
  • › Papain
  • › Bromelain
  • › Cellulase
  • › Invertase
  • › Hemicellulase

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bean & Vegetable Gas Relief by ProCaps Laboratories Drug Interactions

Want to check YOUR meds against Bean & Vegetable Gas Relief?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
333Drugs
122 Moderate 211 Minor

Ingredients driving the most interactions

Legume Enzyme Complex 195

Individual Drug Interactions

The ingredients in Bean & Vegetable Gas Relief interact with 333 drugs. Click any drug to see the details.

1 of the 2 ingredients in Bean & Vegetable Gas Relief interact with drugs. Each result below shows which ingredient is responsible. Legume Enzyme Complex

Each ingredient & the kinds of drugs it affects

For each ingredient in Bean & Vegetable Gas Relief with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Legume Enzyme Complex1 drug type · 195 drugs

Anticholinergic Drugs

Theoretically, taking calabar bean might reduce the effects of anticholinergic drugs.
Physostigmine, a constituent of calabar bean, reverses the effects of belladonna and other drugs with anticholinergic activity.

Likelihood Unlikely Evidence D
Legume Enzyme Complex full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bean & Vegetable Gas Relief, from the product label.

ProCaps Laboratories

See all ProCaps Laboratories products
Name
ProCaps Labs
City
Henderson
State
NV
ZipCode
89011
Phone Number
800.800.1200
Web Address
ProCaps.com
Pharmacist Counseling Corner

Bean & Vegetable Gas Relief by ProCaps Laboratories: Common Questions

Does Bean & Vegetable Gas Relief by ProCaps Laboratories interact with any medications?
Yes. Based on its ingredients, Bean & Vegetable Gas Relief has a known interaction with 333 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bean & Vegetable Gas Relief contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on blood thinners like warfarin?
Not without checking with your pharmacist first. Both papain and bromelain in this product may increase warfarin's effects and side effects — we have a case report of a patient whose blood-thinning level jumped unexpectedly after taking papain. Talk to your pharmacist before starting.
What side effects might I get?
Most common are digestive ones from bromelain — diarrhea, gas, and stomach upset. Papain may cause allergic reactions in sensitive people, including itchy eyes, runny nose, sneezing, cramps, and diarrhea. High doses are unsafe and can rarely cause severe stomach problems.
Is it safe to use while pregnant or breastfeeding?
No, not without talking to your doctor first. Concentrated papain is best avoided in pregnancy due to safety concerns. Bromelain should also be avoided in pregnancy. For breastfeeding, there isn't enough reliable safety data for papain, and bromelain's safety while nursing is unknown.
What are all these enzymes supposed to do?
They're designed to help your body break down carbohydrates and fiber from beans and vegetables, which are common causes of gas. Papain and bromelain digest proteins, while the others target different types of plant sugars and fiber.
Does this actually work for gas relief?
We don't have effectiveness data in our records for this product or its use for gas relief, so I can't tell you whether it works.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bean & Vegetable Gas Relief is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bean & Vegetable Gas Relief label
Go deeper

The Full Monographs Behind Bean & Vegetable Gas Relief’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Calabar Bean

Interacts with 195 drugs

Calabar bean is a highly poisonous West African seed that contains physostigmine, a powerful cholinesterase inhibitor. It is not a safe dietary supplement, and eating the bean can cause seri...

Read the full Calabar Bean monograph → Herb & supplement monograph

Papain

Interacts with 2 drugs

Papain is a protein-digesting enzyme from the papaya plant that is used in digestive supplements and some topical products. While it has clear food and laboratory uses, strong human evidence...

Read the full Papain monograph → Herb & supplement monograph

Bromelain

Interacts with 141 drugs

Bromelain is a group of protein-digesting enzymes from pineapple that people take mainly for inflammation, swelling, and sinus problems. Some early studies are promising, but the overall evi...

Read the full Bromelain monograph →
Sources

Sources & How We Checked

Bean & Vegetable Gas Relief's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 32 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Papain 11 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Saf 1997;17:342-56.
  3. Shuttleworth D, Hill S, Marks R, Connelly DM. Relief of experimentally induced pruritus with a novel eutectic mixture of local anaesthetic agents. Br J Dermatol 1988;119:535-40.
  4. Mansfield LE, Ting S, Haverly RW, Yoo TJ. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge. Ann Allergy 1985;55:541-3.
  5. Martin, T., Uhder, K., Kurek, R., Roeddiger, S., Schneider, L., Vogt, H. G., Heyd, R., and Zamboglou, N. Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial PubMed
  6. Walker-Renard, P. Update on the medicinal management of phytobezoars. Am J Gastroenterol. 1993;88(10):1663-1666.
  7. Tymoszuk D, Wiszniewska M, Walusiak-Skorupa J. Papain-induced occupational rhinoconjunctivitis and asthma - A case report. Med Pr 2016;67(1):109-12. PubMed
  8. Soto-Mera MT, López-Rico MR, Filgueira JF, et al. Occupational allergy to papain. Allergy 2000;55(10):983-4. PubMed
  9. Tarlo SM, Shaikh W, Bell B, et al. Papain-induced allergic reactions. Clin Allergy 1978;8(3):207-15. PubMed
  10. Baur X, König G, Bencze K, Fruhmann G. Clinical symptoms and results of skin test, RAST and bronchial provocation test in thirty-three papain workers: Evidence for strong immunogenic potency and clinically relevant proteolytic e?ects of airborne papain. C
  11. Novey HS, Keenan WJ, Fairshter RD, Wells ID, Wilson AF, Culver BD. Pulmonary disease in workers exposed to papain: clinico-physiological and immunological studies. Clin Allergy 1980;10(6):721-31. PubMed

See these in context on the Papain monograph →

Bromelain 19 references
  1. Nettis E, Napoli G, Ferrannini A, Tursi A. IgE-mediated allergy to bromelain. Allergy 2001;56:257-8. PubMed
  2. Taussig SJ, Batkin S. Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update. J Ethnopharmacol 1988;22:191-203.. PubMed
  3. Bradbrook ID, Morrison PJ, Rogers HJ. The effect of bromelain on the absorption of orally administered tetracycline. Br J Clin Pharmacol 1978;6:552-4. PubMed
  4. Bush TM, Rayburn KS, Holloway SW, et al. Adverse interactions between herbal and dietary substances and prescription medications: a clinical survey. Altern Ther Health Med 2007;13:30-5.
  5. Brien S, Lewith G, Walker AF, et al. Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee: a randomized placebo-controlled pilot study. QJM 2006;99:841-50. PubMed
  6. Mori S, Ojima Y, Hirose T, et al. The clinical effect of proteolytic enzyme containing bromelain and trypsin on urinary tract infection evaluated by double blind method. Acta Obstet Gynaecol Jpn 1972;19:147-53.
  7. Glaser D, Hilberg T. The influence of bromelain on platelet count and platelet activity in vitro. Platelets 2006;17:37-41. PubMed
  8. Heinicke R M, van der Wal L, Yokoyama M. Effect of bromelain (Ananase) on human platelet aggregation. Experientia 1972;28:844-5. PubMed
  9. Gailhofer, G., Wilders-Truschnig, M., Smolle, J., and Ludvan, M. Asthma caused by bromelain: an occupational allergy. Clin Allergy 1988;18(5):445-450. PubMed
  10. Mattei, O., Fabri, G., and Farina, G. [Occupational health experience regarding four cases of asthma due to bromelain (author's transl)]. Medicina del Lavoro 1979;70(5):404-409.
  11. Galleguillos, F. and Rodriguez, J. C. Asthma caused by bromelin inhalation. Clin Allergy 1978;8(1):21-24. PubMed
  12. Perez-Camo I, Quirce S, Duran MA, and et al. Latex allergy: evidence of cross-reactivity with papain and bromelain [abstract]. Allergy 1996;51(suppl 31):48.
  13. Martin GJ, Ehrenreich J, and Asbell N. Bromelain: pineapple proteases with anti-edema activity. Exp Med Surg 1962;20:227-247.
  14. Kasemsuk T, Saengpetch N, Sibmooh N, Unchern S. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis. Clin Rheumatol. 2016 Oct;35(10):2531-40. PubMed
  15. Kutlu Ö, DemirbaS A, Elmas ÖF, Güvenç U, Metin A. Fixed drug eruption: a new side effect of bromelain. Contact Dermatitis 2020. Online ahead of print. PubMed
  16. Shoham Y, Shapira E, Haik J, et al. Bromelain-based enzymatic debridement of chronic wounds: Results of a multicentre randomized controlled trial. Wound Repair Regen 2021;29(6):899-907. PubMed
  17. Pfister P, Garcia Wendel PD, Kim BS, et al. Coagulation side effects of enzymatic debridement in burned patients. Burns 2022. PubMed
  18. Hasham S, Riyat H, Fletcher A, O'Boyle CP, Alexander S. To bleed or not to bleed? Case series and discussion of haemorrhage risk with enzymatic debridement in burn injuries. Scars Burn Heal 2023;9:20595131231168333. PubMed
  19. Leelakanok N, Petchsomrit A, Janurai T, Saechan C, Sunsandee N. Efficacy and safety of bromelain: A systematic review and meta-analysis. Nutr Health 2023. PubMed

See these in context on the Bromelain monograph →

Calabar Bean 2 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.

See these in context on the Calabar Bean monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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