Best Glutamine Peach Mango Ingredients & Drug Interactions
by BPI Sports
What is this page for?
First and foremost: checking Best Glutamine Peach Mango against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Best Glutamine Peach Mango is a dietary supplement by BPI Sports with 7 active ingredients. Its ingredients are commonly taken for common cold and immune support, antioxidant support, skin health and collagen formation.Based on those ingredients, 256 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin C, L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Best Glutamine Peach Mango by BPI Sports
Ask about any prescription or over-the-counter medication and we check it for interactions with Best Glutamine Peach Mango by BPI Sports — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Best Glutamine Peach Mango by BPI Sports
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This powder contains 7 active ingredients centered on glutamine — a building block amino acid. You get straight L-glutamine, glutamine alpha-ketoglutarate, and a proprietary glutamine blend alongside glutamic acid and N-acetyl-L-glutamine.
It also contains vitamin C. The remaining ingredients — citric acid, silica, natural and artificial flavors, malic acid, sucralose, acesulfame-K, and colorants — are fillers and binders that give the powder its texture, taste, and shelf life.
Does it work?
Moderate evidence
Glutamine is effective for sickle cell disease. The evidence is possibly effective for HIV/AIDS-related muscle wasting, recovery after surgery, and critical illness from trauma.
Vitamin C is effective for treating vitamin C deficiency. There's possibly effective evidence for vitamin C in anemia of chronic disease, atrial fibrillation prevention, cataracts, and exercise-induced respiratory infections.
We hold no established effectiveness data for glutamic acid, N-acetyl-L-glutamine, or L-alanyl-L-glutamine.
How safe is it?
Well-documented data
Both glutamine ingredients and vitamin C are generally well tolerated. The most common side effects from glutamine are gastrointestinal — belching, bloating, gas, constipation, diarrhea, nausea, and stomach pain.
Headache and musculoskeletal pain have also been reported. Vitamin C at high doses can cause abdominal cramps, heartburn, diarrhea, and nausea; side effects are more likely above 2 grams daily.
Glutamine is not recommended in supplemental doses for pregnant women or while breastfeeding unless a doctor advises it; vitamin C at normal prenatal amounts is fine, but high-dose supplements should be avoided in pregnancy and lactation without medical guidance. People with kidney or liver disease should only use glutamine under medical supervision.
Meds to double-check
Moderate interaction found
Check with your pharmacist before using this if you take any blood thinners (especially warfarin), hormonal birth control or hormone replacement therapy, seizure medications, cancer chemotherapy, or thyroid medication. Vitamin C can also affect aluminum absorption and one antipsychotic drug (fluphenazine).
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you're recovering from surgery, managing critical illness, or treating HIV/AIDS wasting (under medical care), this product has evidence to support those uses. If you take warfarin, oral contraceptives, anticonvulsant drugs, or thyroid medication, talk to your pharmacist before starting — the interactions matter and may need dose adjustments or timing changes.
People with kidney or liver disease need doctor approval. Gastrointestinal side effects are common, especially at higher doses.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 21, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Best Glutamine Peach Mango, straight from the product label.
| Brand | BPI Sports |
|---|---|
| Barcode (UPC) | 811213023799 |
| Net contents | 14.1 Oz(s); 400 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Oct 21, 2017 |
| DSLD ID | 79834 |
| Product type | Other Combinations |
| Supplement form | Powder |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Best Glutamine Peach Mango by BPI Sports, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Glutamine | 0 NP | -- |
| Vitamin C | 500 mg | 833% |
| Glutamic Acid | 0 NP | -- |
| N-Acetyl-L-Glutamine | 0 NP | -- |
| L-Alanyl-L-Glutamine | 0 NP | -- |
| Best Glutamine Blend (Proprietary) | 6.5 Gram(s) | -- |
| Glutamine Alpha-Ketoglutarate | 0 NP | -- |
| Glutamine | 0 NP | -- |
Other ingredients: Citric Acid, Silica, Natural and Artificial flavors, Malic Acid, Sucralose, Acesulfame-K, Oligopeptide-Enzymatic Technology, FD&C Yellow No. 5, FD&C Red No.40
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General
Rev. 01-004-BGL008 10/16
General Statements
When combined with a proper exercise and nutrition regimen. Statements based on early-stage independent 3rd party in vivo and / or in vitro model scientific research data findings for individual ingredients.
Glutamine is the most abundant amino acid (a building block for proteins) in the body, and one of the best supplements for promoting recovery and lean muscle building. Strenuous exercise can lower glutamine levels causing stress to the body and immune system. However, with proper glutamine supplementation you can help your body recover and rebuild faster.
Lean muscle Recovery
Natural and artificial flavors
New!
Essential Amino Acid for intense training
Promotes recovery Supports lean muscle Promotes Glycogen replenishment
To report an adverse event or for more information call: 954.926.0900 (tel)
Facebook www.facebook.com/BPIonline
Brand IP Statement(s)
Why is Best Glutamine better?
Best Glutamine is designed to prevent protein catabolism (the breakdown of muscle proteins) and support your efforts to train harder and longer.
Best Glutamine comes in delicious flavors to support recovery and promote lean muscle.
Be better. Be stronger. BPI.
Formula
Best Glutamine combines 6 advanced forms of Glutamine and is designed to promote a rapid rise in cellular Glutamine levels and Glutamine stores in muscle.
6 advanced forms of Glutamine
L-Glutamine Glutamine AKG Glutamic Acid N-Acetyl-L Glutamine Glutamine (as Oligopeptide Enzymatic Technology) L-Alanyl-L Glutamine
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Take 1 scoop blended into 6oz water pre/post workout
Please read entire label before use. Suggested Use: Take one (1) serving (1 scoop) with approximately 6 ounces of water or juice, or as directed by a qualified healthcare practitioner. Can be taken before, during or after workouts. On non-training days, take one (1) serving (1 scoop) first thing in the morning on an empty stomach, or as directed by a qualified healthcare practitioner.
Precautions
Warnings: Not intended for use by persons under age 18.
Do not exceed recommended dose.
Get the consent of a licensed physician before using this product, especially if you are taking medication, have a medical condition, you are pregnant, nursing or thinking about becoming pregnant.
Discontinue use two weeks prior to surgery.
Keep this product and all supplements out of the reach of children.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Best Glutamine Peach Mango by BPI Sports label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Best Glutamine Peach Mango by BPI Sports
These are the 7 active ingredients this product is made of. Select any to open its full monograph.
Serving size8 Gram(s) Dosage formPowder Servings per container50 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Vitamin C
Interacts with207 drugs
Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for im...
Vitamin C monograph & interactionsBest Glutamine Blend (Proprietary)
- › L-Glutamine
- › Glutamic Acid
- › N-Acetyl-L-Glutamine
- › L-Alanyl-L-Glutamine
- › Glutamine Alpha-Ketoglutarate
- › Glutamine
Other (inactive) ingredients: Citric Acid, Silica, Natural and Artificial flavors, Malic Acid, Sucralose, Acesulfame-K, Oligopeptide-Enzymatic Technology, FD&C Yellow No. 5, FD&C Red No.40. These complete the product’s ingredient list but are not active constituents.
Best Glutamine Peach Mango by BPI Sports Drug Interactions
HelloPharmacist Interaction Report
Best Glutamine Peach Mango by BPI Sports interacts with several medication types.
The most serious concern is with blood thinners like warfarin (Coumadin) — vitamin C in this product may reduce warfarin's effectiveness and lower your blood clotting ability, which is a Moderate severity issue.
Read the full breakdown — every affected drug type, severity by severity
Vitamin C also has Moderate interactions with hormonal birth control and hormone replacement therapy (it may raise estrogen levels), certain chemotherapy drugs called alkylating agents (antioxidants might blunt their effect), antitumor antibiotics used in cancer treatment, and the antiviral drug indinavir. Additionally, vitamin C can increase aluminum absorption from aluminum compounds and may affect levothyroxine (thyroid medication) absorption — both Moderate.
There's also a Moderate interaction with the antipsychotic fluphenazine.
The glutamine ingredients in this product have a Moderate interaction with anticonvulsant medications (seizure drugs) — glutamine breaks down into glutamate, which theoretically might work against anticonvulsants, though this hasn't been reported in humans yet.
We couldn't check glutamic acid, N-acetyl-L-glutamine, or L-alanyl-L-glutamine for interactions. Altogether, these interactions span 256 individual medications.
Use the medication checker on this page to look up your exact drugs before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Best Glutamine Peach Mango?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Best Glutamine Peach Mango interact with 256 drugs. Click any drug to see the details.
2 of the 7 ingredients in Best Glutamine Peach Mango interact with drugs. Each result below shows which ingredient is responsible. Vitamin C L-Glutamine
AcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Acetazolamide interactionAlginic Acid, Aluminum HydroxideRafton
How Alginic Acid, Aluminum Hydroxide interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Alginic Acid, Aluminum Hydroxide interactionAltretamineHexalen
How Altretamine interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Altretamine interactionAluminum Acetate, Benzethonium ChlorideBuro-Sol Otic Solution
How Aluminum Acetate, Benzethonium Chloride interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Acetate, Benzethonium Chloride interactionAluminum ChlorideAluminum Chloride, Anhydrol Forte, Driclor, Drysol
How Aluminum Chloride interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Chloride interactionAluminum HydroxideAlu-Cap, Amphojel, Gaviscon
How Aluminum Hydroxide interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAspirin, Aluminum Moderate
Interaction Summary
Acidification of the urine by vitamin C might increase aspirin levels.
Read the full Vitamin C + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum, Aspirin Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAluminum Hydroxide, Magnesium Hydroxide (otc Drug)Maalox, Mucogel
How Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interactionAluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug)Mylanta
How Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interactionAluminum, CalciumDomeboro
How Aluminum, Calcium interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum, Calcium interactionAluminum, Magnesium (otc Drug)Almagel
How Aluminum, Magnesium (otc Drug) interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum, Magnesium (otc Drug) interactionAluminum, Magnesium Hydroxide (otc Drug)Wingel
How Aluminum, Magnesium Hydroxide (otc Drug) interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum, Magnesium Hydroxide (otc Drug) interactionAminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Aminophylline, Amobarbital, Ephedrine interactionAmobarbitalAmytal
How Amobarbital interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Amobarbital interactionAmobarbital, Ephedrine SulfateEphedrine & Amytal
How Amobarbital, Ephedrine Sulfate interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Amobarbital, Ephedrine Sulfate interactionAmobarbital, SecobarbitalTuinal
How Amobarbital, Secobarbital interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Amobarbital, Secobarbital interactionAprobarbital, Butabarbital, PhenobarbitalTriple Barbital
How Aprobarbital, Butabarbital, Phenobarbital interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Aprobarbital, Butabarbital, Phenobarbital interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAspirin, Aluminum Moderate
Interaction Summary
Acidification of the urine by vitamin C might increase aspirin levels.
Read the full Vitamin C + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionBazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CEstrogens Moderate
Interaction Summary
Vitamin C might increase blood levels of estrogens.
Read the full Vitamin C + Bazedoxifene Acetate, Conjugated Estrogens interactionBelladonna, Caffeine, Ergotamine, PentobarbitalMicomp PB
How Belladonna, Caffeine, Ergotamine, Pentobarbital interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Belladonna, Caffeine, Ergotamine, Pentobarbital interactionBelladonna, PhenobarbitalBellophen, Susano
How Belladonna, Phenobarbital interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Belladonna, Phenobarbital interactionBellafoline, Caffeine, Ergotamine Tartrate, PentobarbitalCafergot PB
How Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Bendamustine Hydrochloride interactionBleomycinBlenoxane
How Bleomycin interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAntitumor Antibiotics Moderate
Interaction Summary
Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
Read the full Vitamin C + Bleomycin interactionBusulfanBusulfex, Myleran
How Busulfan interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Busulfan interactionButalbital, Phenobarbital, SecobarbitalTribarb
How Butalbital, Phenobarbital, Secobarbital interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Butalbital, Phenobarbital, Secobarbital interactionCarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Carbamazepine interactionCarboplatinParaplatin
How Carboplatin interacts with Best Glutamine Peach Mango — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Carboplatin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Best Glutamine Peach Mango with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Vitamin C
Alkylating Agents
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.
Aluminum
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Research in animals and humans shows that vitamin C increases aluminum absorption, theoretically by chelating aluminum and keeping it in solution where it is available for absorption. In people with normal renal function, urinary excretion of aluminum will likely increase, making aluminum retention and toxicity unlikely. Patients with renal failure who take aluminum-containing compounds such as phosphate binders should avoid vitamin C supplements in doses above the recommended dietary allowances.
Antitumor Antibiotics
Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as doxorubicin. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy.
Estrogens
Vitamin C might increase blood levels of estrogens.
Increases in plasma estrogen levels of up to 55% occur under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. Increases in plasma estrogen levels may occur when patients who are deficient in vitamin C take supplements. Monitor these patients for estrogen-related side effects.
Fluphenazine (Prolixin)
Theoretically, vitamin C might decrease levels of fluphenazine.
In one patient there was a clinically significant decrease in fluphenazine levels when vitamin C (500 mg twice daily) was started. The mechanism is not known, and there is no further data to confirm this interaction.
Indinavir (Crixivan)
Vitamin C can modestly reduce indinavir levels.
One pharmacokinetic study shows that taking vitamin C 1 gram orally once daily along with indinavir 800 mg orally three times daily reduces the area under the concentration-time curve of indinavir by 14%. The mechanism of this interaction is unknown, but it is unlikely to be clinically significant in most patients. The effect of higher doses of vitamin C on indinavir levels is unknown.
Levothyroxine (Synthroid, Others)
Vitamin C can increase levothyroxine absorption.
Two clinical studies in adults with poorly controlled hypothyroidism show that swallowing levothyroxine with a glass of water containing vitamin C 500-1000 mg in solution reduces thyroid stimulating hormone (TSH) levels and increases thyroxine (T4) levels when compared with taking levothyroxine alone. This suggests that vitamin C increases the oral absorption of levothyroxine, possibly due to a reduction in pH.
Warfarin (Coumadin)
High-dose vitamin C might reduce the levels and effectiveness of warfarin.
Vitamin C in high doses may cause diarrhea and possibly reduce warfarin absorption. There are reports of two people who took up to 16 grams daily of vitamin C and had a reduction in prothrombin time. Lower doses of 5-10 grams daily can also reduce warfarin absorption. In many cases, this does not seem to be clinically significant. However, a case of warfarin resistance has been reported for a patient who took vitamin C 500 mg twice daily. Cessation of vitamin C supplementation resulted in a rapid increase in international normalized ratio (INR). Tell patients taking warfarin to avoid taking vitamin C in excessively high doses (greater than 10 grams daily). Lower doses may be safe, but the anticoagulation activity of warfarin should be monitored. Patients who are stabilized on warfarin while taking vitamin C should avoid adjusting vitamin C dosage to prevent the possibility of warfarin resistance.
Acetaminophen (Tylenol, Others)
High-dose vitamin C might slightly prolong the clearance of acetaminophen.
A small pharmacokinetic study in healthy volunteers shows that taking high-dose vitamin C (3 grams) 1.5 hours after taking acetaminophen 1 gram slightly increases the apparent half-life of acetaminophen from around 2.3 hours to 3.1 hours. Ascorbic acid competitively inhibits sulfate conjugation of acetaminophen. However, to compensate, elimination of acetaminophen glucuronide and unconjugated acetaminophen increases. This effect is not likely to be clinically significant.
Aspirin
Acidification of the urine by vitamin C might increase aspirin levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction is not clinically significant.
Choline Magnesium Trisalicylate (Trilisate)
Acidification of the urine by vitamin C might increase choline magnesium trisalicylate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.
Niacin
Vitamin C might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as vitamin C, or to the combination. It also is not known whether it will occur in other patient populations.
Salsalate (Disalcid)
Acidification of the urine by vitamin C might increase salsalate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams/day vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.
L-Glutamine
Anticonvulsants
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.
Brand information
Manufacturer and brand details for Best Glutamine Peach Mango, from the product label.
BPI Sports
See all BPI Sports products- Name
- BPI Sports
- Street Address
- 3149 SW 42nd St. Suite 200
- City
- Hollywood
- State
- FL
- ZipCode
- 33312
- Phone Number
- 954.926.0900
- Web Address
- www.bpisports.com
Best Glutamine Peach Mango by BPI Sports: Common Questions
Does Best Glutamine Peach Mango by BPI Sports interact with any medications?
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Does vitamin C in this product affect how much vitamin C I can take daily?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Best Glutamine Peach Mango’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Vitamin C
Interacts with 207 drugsVitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for immune function, collagen, and acts as an...
Read the full Vitamin C monograph → Herb & supplement monographGlutamine
Interacts with 50 drugsGlutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...
Read the full Glutamine monograph →Sources & How We Checked
Best Glutamine Peach Mango's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 62 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Glutamine 11 references
- Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
- Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
- Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
- Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
- Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
- Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
- Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
- Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
- Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
- Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
- Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed
Vitamin C 51 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Back DJ, Breckenridge AM, MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516.
- Morris JC, Beeley L, Ballantine N. Interaction of ethinyloestradiol with ascorbic acid in man [letter]. Br Med J (Clin Res Ed) 1981;283:503.
- Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8.
- Dwyer JH, Merz NB, Shirocre AM, et al. Progression of early atherosclerosis and intake of vitamin C and vitamin E from supplements and food. The Los Angeles Atherosclerosis Study. 41st Annual Conference on Cardiovascular Disease Epidemiology and Prevent
- Levine M, Rumsey SC, Daruwala R, et al. Criteria and recommendations for vitamin C intake. JAMA 1999;281:1415-23. PubMed
- Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
- Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
- Houston JB, Levy G. Drug biotransformation interactions in man VI: Acetaminophen and ascorbic acid. J Pharm Sci 1976;65:1218-21. PubMed
- Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-93. DOI
- Rosenthal G. Interaction of ascorbic acid and warfarin. JAMA 1971;215:1671. DOI
- Hume R, Johnstone JM, Weyers E. Interaction of ascorbic acid and warfarin. JAMA 1972;219:1479. DOI
- Smith EC, Skalski RJ, Johnson GC, Rossi GV. Interaction of ascorbic acid and warfarin. JAMA 1972;221:1166. DOI
- Traxer O, Huet B, Poindexter J, et al. Effect of ascorbic acid consumption on urinary stone risk factors. J Urol 2003;170:397-401.. PubMed
- Domingo JL, Gomez M, Llobet JM, Richart C. Effect of ascorbic acid on gastrointestinal aluminum absorption (letter). Lancet 1991;338:1467.
- Domingo JL, Gomez M, Llobet JM, Corbella J. Influence of some dietary constituents on aluminum absorption and retention in rats. Kidney Int 1991;39:598-601. PubMed
- Partridge NA, Regnier FE, White JL, Hem SL. Influence of dietary constituents on intestinal absorption of aluminum. Kidney Int 1989;35:1413-7. PubMed
- Mc Leod DC, Nahata MC. Inefficacy of ascorbic acid as a urinary acidifier (letter). N Engl J Med 1977;296:1413. DOI
- Hansten PD, Hayton WL. Effect of antacid and ascorbic acid on serum salicylate concentration. J Clin Pharmacol 1980;20:326-31. PubMed
- Dysken MW, Cumming RJ, Channon RA, Davis JM. Drug interaction between ascorbic acid and fluphenazine. JAMA 1979;241:2008. DOI
- Vihtamaki T, Parantainen J, Koivisto AM, et al. Oral ascorbic acid increases plasma oestradiol during postmenopausal hormone replacement therapy. Maturitas 2002;42:129-35. PubMed
- Slain D, Amsden JR, Khakoo RA, et al. Effect of high-dose vitamin C on the steady-state pharmacokinetics of the protease inhibitor indinavir in healthy volunteers. Pharmacotherapy 2005;25:165-70. PubMed
- Cheung MC, Zhao XQ, Chait A, et al. Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL. Arterioscler Thromb Vasc Biol 2001;21:1320-6. PubMed
- Feetam CL, Leach RH, Meynell MJ. Lack of a clinically important interaction between warfarin and ascorbic acid. Toxicol Appl Pharmacol 1975;31:544-7. PubMed
- Weintraub M, Griner PF. Warfarin and ascorbic acid: lack of evidence for a drug interaction. Toxicol Appl Pharmacol 1974;28:53-6. PubMed
- Lee DH, Folsom AR, Harnack L, et al. Does supplemental vitamin C increase cardiovascular disease risk in women with diabetes? Am J Clin Nutr 2004;80:1194-200. PubMed
- Taylor EN, Stampfer MJ, Curhan GC. Dietary factors and the risk of incident kidney stones in men: new insights after 14 years of follow-up. J Am Soc Nephrol 2004;15:3225-32. PubMed
- Ward NC, Hodgson JM, Croft KD, et al. The combination of vitamin C and grape-seed polyphenols increases blood pressure: a randomized, double-blind, placebo-controlled trial. J Hypertens 2005;23:427-34.. PubMed
- Prasad KN. Rationale for using high-dose multiple dietary antioxidants as an adjunct to radiation therapy and chemotherapy. J Nutr 2004;134:3182S-3S. PubMed
- Conklin KA. Cancer chemotherapy and antioxidants. J Nutr 2004;134:3201S-3204S. PubMed
- Fairweather-Tait S, Hickson K, McGaw B, et al. Orange juice enhances aluminium absorption from antacid preparation. Eur J Clin Nutr. 1994;48(1):71-3.
- Gruenwald, J., Graubaum, H. J., Busch, R., and Bentley, C. Safety and tolerance of ester-C compared with regular ascorbic acid. Adv.Ther. 2006;23(1):171-178.
- Rahimi, R., Nikfar, S., Rezaie, A., and Abdollahi, M. A meta-analysis on the efficacy and safety of combined vitamin C and E supplementation in preeclamptic women. Hypertens.Pregnancy. 2009;28(4):417-434. PubMed
- Einerson, B., Nathorn, C., Kitiyakara, C., Sirada, M., and Thamlikitkul, V. The efficacy of ascorbic acid in suboptimal responsive anemic hemodialysis patients receiving erythropoietin: a meta-analysis. J Med.Assoc.Thai. 2011;94 Suppl 1:S134-S146.
- Li, G., Li, L., Yu, C., and Chen, L. Effect of vitamins C and E supplementation on Helicobacter pylori eradication: a meta-analysis. Br.J Nutr 2011;106(11):1632-1637.
- Chen X, Shen L, Gu X, et al. High-dose supplementation with vitamin C--induced pediatric urolithiasis: the first case report in a child and literature review. Urology. 2014;84(4):922-4. PubMed
- Sattar A, Willman JE, Kolluri R. Possible warfarin resistance due to interaction with ascorbic acid: case report and literature review. Am J Health Syst Pharm. 2013;70(9):782-6. PubMed
- Yaich S, Chaabouni Y, Charfeddine K, et al. Secondary oxalosis due to excess vitamin C intake: a cause of graft loss in a renal transplant recipient. Saudi J Kidney Dis Transpl. 2014;25(1):113-6. PubMed
- Jalloh MA, Gregory PJ, Hein D, et al. Dietary supplement interactions with antiretrovirals: a systematic review. Int J STD AIDS. 2017 Jan;28(1):4-15. PubMed
- Rumbold A, Ota E, Nagata C, Shahrook S, Crowther CA. Vitamin C supplementation in pregnancy. Cochrane Database Syst Rev. 2015;(9):CD004072. PubMed
- Seo MS, Kim JK, Shim JY. High-dose vitamin C promotes regression of multiple pulmonary metastases originating from hepatocellular carcinoma. Yonsei Med J. 2015;56(5):1449-52. PubMed
- Skelin M, Lucijanic T, Amidzic Klaric D, et al. Factors Affecting Gastrointestinal Absorption of Levothyroxine: A Review. Clin Ther. 2017 Feb;39(2):378-403. PubMed
- Jiang K, Tang K, Liu H, Xu H, Ye Z, Chen Z. Ascorbic acid supplements and kidney stones incidence among men and women: a systematic review and meta-analysis. Urol J. 2019;16(2):115-120.
- Thomas S, Patel D, Bittel B, et al. Effect of High-Dose Zinc and Ascorbic Acid Supplementation vs Usual Care on Symptom Length and Reduction Among Ambulatory Patients With SARS-CoV-2 Infection: The COVID A to Z Randomized Clinical Trial. JAMA Netw Open. 2 PubMed
- Giffen MA, McLemore JL. Hyperoxalosis Secondary to Intravenous Vitamin C Administration as a Non-Allopathic Treatment for Cancer. Acad Forensic Pathol 2019;9(1-2):118-126. PubMed
- Maike A, Sturgill D, Gallan A. Oxalate Nephropathy in a Renal Transplant Recipient After Receiving High Dose Ascorbic Acid. Am J Med Sci 2021. PubMed
- Shen ZY, Chen YR, Wang MC, Chang SS. High-dose vitamin C-induced acute oxalate nephropathy in a renal transplant recipient: a case report and literature review. Asian J Surg 2022. PubMed
- Yanase F, Spano S, Maeda A, et al. Mega-dose sodium ascorbate: a pilot, single-dose, physiological effect, double-blind, randomized, controlled trial. Crit Care 2023;27(1):371. PubMed
- Sharma Y, Sumanadasa S, Shahi R, et al. Efficacy and safety of vitamin C supplementation in the treatment of community-acquired pneumonia: a systematic review and meta-analysis with trial sequential analysis. Sci Rep 2024;14(1):11846. PubMed
- Pejcic AV, Petrovic NZ, Djordjic MD, Milosavljevic MN. Vitamin C Levels in Pregnant Women and the Efficacy of Vitamin C Supplements in Preventing Premature Rupture of Membranes: A Systematic Review and Meta-Analysis. Balkan Med J 2024;41(4):248-260. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC