Beta-Gest Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Beta-Gest against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Beta-Gest is a dietary supplement by NeoLife Nutritionals with 5 active ingredients. Its ingredients are commonly taken for digestive support for protein digestion, wound cleaning (debridement of dead tissue), sore throat and inflammation.Based on those ingredients, 61 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Betaine Hydrochloride, Lemon Pectin, Papain. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Beta-Gest by NeoLife Nutritionals
Ask about any prescription or over-the-counter medication and we check it for interactions with Beta-Gest by NeoLife Nutritionals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Beta-Gest by NeoLife Nutritionals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Beta-Gest has 5 active ingredients. Papain is an enzyme from papaya that breaks down proteins; lactase is an enzyme that breaks down lactose (milk sugar); betaine hydrochloride is a compound that increases stomach acid; acid stable protease is another protein-digesting enzyme; and lemon pectin is a soluble fiber from citrus.
Together, they're designed to support digestion. The tablet also contains several inactive ingredients—cellulose, silicates, and other binders and colorants—to hold the formulation together.
Does it work?
Strong evidence
The evidence we hold doesn't establish that any of these ingredients work for specific conditions. Lactase is rated effective for lactose intolerance—that's the one solid finding.
Lemon pectin is possibly effective for high cholesterol. For everything else—including papain for cancer, dental health, muscle soreness, shingles, or parasites; betaine hydrochloride for heartburn or thyroid function; and protease for any named condition—the evidence is either insufficient or absent from our data.
How safe is it?
Well-documented data
Papain is generally tolerated as a food but may irritate the digestive tract or trigger allergic reactions in sensitive people. High doses may cause serious problems like severe inflammation or perforation of the esophagus.
You should avoid concentrated papain and unripe papaya during pregnancy; during breastfeeding, there isn't enough safety data. Betaine hydrochloride is not safe if you have ulcers, gastritis, or true acid reflux, and should be avoided in pregnancy and breastfeeding.
Lemon pectin is generally well tolerated, though it can occasionally cause gas, loose stools, or mild cramps, and rare allergic reactions including anaphylaxis. Lactase and acid stable protease are generally well tolerated, though lactase rarely causes allergic skin reactions, and protease may occasionally cause digestive upset or allergy symptoms.
Meds to double-check
Moderate interaction found
Double-check before using Beta-Gest if you take warfarin (blood thinner), lovastatin or other cholesterol drugs, tetracycline antibiotics, digoxin (heart medication), H2-blockers, antacids, or proton pump inhibitors (acid-reducing medications). Papain is the biggest concern; pectin and betaine hydrochloride account for the rest.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is for people looking to support digestion with plant enzymes. If you take warfarin, lovastatin, tetracycline antibiotics, digoxin, H2-blockers, antacids, or PPIs, check with your pharmacist first—this product may interfere with them.
Those with ulcers or reflux should avoid it. Talk to your pharmacist about your medications and any allergies before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Beta-Gest, straight from the product label.
| Brand | NeoLife Nutritionals |
|---|---|
| Barcode (UPC) | 3521s |
| Net contents | 100 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2023 |
| DSLD ID | 303275 |
| Product type | Other Combinations |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Beta-Gest by NeoLife Nutritionals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Papain | 30 mg | -- |
| Lactase | 24 mg | -- |
| Betaine Hydrochloride | 825 mg | -- |
| acid stable Protease | 120 mg | -- |
| Lemon Pectin | 9 mg | -- |
Other ingredients: Microcrystalline Cellulose, Magnesium Silicate, Hydroxypropyl Methylcellulose, Food Glaze, Beet, Powder, Silicon Dioxide, Triacetin, Magnesium Stearate, Titanium Dioxide, Licorice, Powder, natural mint extract, Natural color, Carmine
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Protease, hydrochloric acid (from betaine HCl) and lactase reinforce normal stomach digestive secretions compromised by age, stress, alcohol or antacid overuse. Hydrochloric acid readies protein for enzymatic digestion, activates natural gastric enzyme, pepsinogen, and is needed for absorption of phosphorus, iron, magnesium, calcium and B12. Lactase assists digestion of lactose (milk sugar).
Plant sourced enzymes support efficient digestion
Storage
Store in a cool, dry place away from direct sunlight.
Precautions
Packaged with safety seal.
Formulation
GMO Free
Based in Nature
Stomach Targeted
Made in U.S.A.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Use: 1 to 3 tablets daily, immediately before or with food.
General Statements
Not sold in retail stores. Available Exclusively from NeoLife Promoters.
Leading edge nutrition since 1958. Based in Nature, Backed by Science.
Seals/Symbols
SAB Scientific Advisory Board NeoLife Scientific Advisory Board
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Beta-Gest by NeoLife Nutritionals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Beta-Gest by NeoLife Nutritionals
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container33 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Papain
Interacts with2 drugs
Papain is a protein-digesting enzyme from the papaya plant that is used in digestive supplements and some topical products. While it has clear food an...
Papain monograph & interactionsLactase
No knowninteractions
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...
Lactase monograph & interactionsBetaine Hydrochloride
Interacts with36 drugs
Betaine hydrochloride is a supplement used to temporarily increase stomach acid in people who may have low acid levels. Evidence for its benefits is l...
Betaine Hydrochloride monograph & interactionsAcid stable Protease
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Acid stable Protease monograph & interactionsLemon Pectin
Interacts with23 drugs
Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly he...
Lemon Pectin monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Magnesium Silicate, Hydroxypropyl Methylcellulose, Food Glaze, Beet, Powder, Silicon Dioxide, Triacetin, Magnesium Stearate, Titanium Dioxide, Licorice, Powder, Natural mint extract, Natural color, Carmine. These complete the product’s ingredient list but are not active constituents.
Beta-Gest by NeoLife Nutritionals Drug Interactions
HelloPharmacist Interaction Report
Beta-Gest by NeoLife Nutritionals contains ingredients that interact with several medications, and you'll want to double-check yours before starting.
The most serious interaction is with warfarin (Coumadin), a blood thinner: papain in this product may theoretically increase warfarin's effects and side effects, and one case report documented a patient's blood-thinning level spike after taking a papain supplement. That's a Moderate concern.
Read the full breakdown — every affected drug type, severity by severity
Lemon pectin in the product can reduce how your body absorbs three medications: lovastatin (a cholesterol drug), tetracycline antibiotics, and digoxin (a heart medication)—all rated Moderate. Betaine hydrochloride may decrease the effectiveness of acid-reducing medications: H2-blockers like famotidine, antacids, and proton pump inhibitors (PPIs) like omeprazole—all Minor interactions.
Altogether, these interactions span 61 individual medications.
Lactase and acid stable protease have no interactions documented in our data, though that doesn't guarantee none exist. Run your exact medications through the checker on this page to be sure.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Beta-Gest?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Beta-Gest interact with 61 drugs. Click any drug to see the details.
3 of the 5 ingredients in Beta-Gest interact with drugs. Each result below shows which ingredient is responsible. Betaine Hydrochloride Lemon Pectin Papain
Amphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Amphotericin, Tetracycline interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionChlortetracyclineAureomycin
How Chlortetracycline interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Chlortetracycline interactionDemeclocyclineDeclomycin
How Demeclocycline interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Demeclocycline interactionDigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinDigoxin (lanoxin) Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
Read the full Lemon Pectin + Digoxin interactionDoripenemDoribax
How Doripenem interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Doripenem interactionDoxycyclineDoryx, Doxy, Doxy-D, Doxycin, Doxycycline Injection, Doxylin +6 more
How Doxycycline interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Doxycycline interactionDoxycycline HyclateActiclate, Acticlate Cap, Lymepak
How Doxycycline Hyclate interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Doxycycline Hyclate interactionDoxycycline MonohydrateErfacea
How Doxycycline Monohydrate interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Doxycycline Monohydrate interactionDoxycylineDoxychel
How Doxycyline interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Doxycyline interactionEravacyclineXerava
How Eravacycline interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Eravacycline interactionLovastatinAltocor, Mevacor
How Lovastatin interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinLovastatin (mevacor) Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Read the full Lemon Pectin + Lovastatin interactionMetronidazole, Tetracyline, Bismuth Subcitrate PotassiumPylera
How Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interactionMinocyclineAcnamino MR, Aknemin, Amzeeq, Arestin Miscrosperes, Dynacin, Minocin +6 more
How Minocycline interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Minocycline interactionMinocycline HydrochlorideMinolira, Ximino
How Minocycline Hydrochloride interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Minocycline Hydrochloride interactionNiacin, LovastatinAdvicor
How Niacin, Lovastatin interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinLovastatin (mevacor) Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Read the full Lemon Pectin + Niacin, Lovastatin interactionOmadacycline (iv)Nuzyra
How Omadacycline (iv) interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Omadacycline (iv) interactionOmadacycline (oral)Nuzyra
How Omadacycline (oral) interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Omadacycline (oral) interactionOxytetracyclineTerramycin
How Oxytetracycline interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Oxytetracycline interactionOxytetracycline, Phenazopyridine, SulfamethizoleUrobiotic
How Oxytetracycline, Phenazopyridine, Sulfamethizole interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Oxytetracycline, Phenazopyridine, Sulfamethizole interactionRetapamulinAltabax, Altargo
How Retapamulin interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Retapamulin interactionTetracyclineAchromycin, Achromycin V, Nor-Tet, Robitet, Sumycin, Sumycin 250 +6 more
How Tetracycline interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Tetracycline interactionTigecyclineTygacil
How Tigecycline interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Lemon PectinTetracycline Antibiotics Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
Read the full Lemon Pectin + Tigecycline interactionWarfarinWarfarin
How Warfarin interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
PapainWarfarin (coumadin) Moderate
Interaction Summary
Theoretically, papain might increase the effects and side effects of warfarin.
Read the full Papain + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
PapainWarfarin (coumadin) Moderate
Interaction Summary
Theoretically, papain might increase the effects and side effects of warfarin.
Read the full Papain + Warfarin Sodium interactionAlginic Acid, Aluminum HydroxideRafton
How Alginic Acid, Aluminum Hydroxide interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Betaine HydrochlorideAntacids Minor
Interaction Summary
Betaine hydrochloride increases stomach acidity and could decrease the effects of antacids.
Read the full Betaine Hydrochloride + Alginic Acid, Aluminum Hydroxide interactionAluminum HydroxideAlu-Cap, Amphojel, Gaviscon
How Aluminum Hydroxide interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Betaine HydrochlorideAntacids Minor
Interaction Summary
Betaine hydrochloride increases stomach acidity and could decrease the effects of antacids.
Read the full Betaine Hydrochloride + Aluminum Hydroxide interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Betaine HydrochlorideAntacids Minor
Interaction Summary
Betaine hydrochloride increases stomach acidity and could decrease the effects of antacids.
Read the full Betaine Hydrochloride + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Betaine HydrochlorideAntacids Minor
Interaction Summary
Betaine hydrochloride increases stomach acidity and could decrease the effects of antacids.
Read the full Betaine Hydrochloride + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAluminum Hydroxide, Magnesium Hydroxide (otc Drug)Maalox, Mucogel
How Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interacts with Beta-Gest — through 1 ingredient. Tap an ingredient for the detail:
Betaine HydrochlorideAntacids Minor
Interaction Summary
Betaine hydrochloride increases stomach acidity and could decrease the effects of antacids.
Read the full Betaine Hydrochloride + Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Beta-Gest with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Betaine Hydrochloride
Antacids
Betaine hydrochloride increases stomach acidity and could decrease the effects of antacids.
In human research, betaine hydrochloride increases stomach acidity. Antacids are taken to decrease stomach acidity. Theoretically, taking betaine hydrochloride along with antacids might decrease the effects of the antacids.
H2-Blockers
Betaine hydrochloride increases stomach acidity and could decrease the effects of H2-blockers.
In human research, betaine hydrochloride increases stomach acidity. H2-blockers are used to decrease stomach acidity. Theoretically, taking betaine hydrochloride along with H2-blockers might decrease the effects of H2-blockers.
Proton Pump Inhibitors (Ppis)
Betaine hydrochloride increases stomach acidity and could decrease the effects of PPIs.
In human research, betaine hydrochloride increases stomach acidity. PPIs are used to decrease stomach acidity. Theoretically, taking betaine hydrochloride along with PPIs might decrease the effects of PPIs
Lemon Pectin
Digoxin (Lanoxin)
Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.
Lovastatin (Mevacor)
Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.
Tetracycline Antibiotics
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.
Papain
Warfarin (Coumadin)
Theoretically, papain might increase the effects and side effects of warfarin.
In one case report, a patient previously stable on warfarin was found to have an international normalization ratio (INR) of 7.4, which was attributed to ingestion of a supplement containing papain from papaya extract.
Brand information
Manufacturer and brand details for Beta-Gest, from the product label.
NeoLife Nutritionals
See all NeoLife Nutritionals products- Name
- NeoLife International, LLC
- City
- Santa Clara
- State
- CA
- ZipCode
- 95054
- Web Address
- NeoLife.com
Beta-Gest by NeoLife Nutritionals: Common Questions
Does Beta-Gest by NeoLife Nutritionals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is it safe to take during pregnancy?
What is papain, and why is it in here?
Can I use this if I have acid reflux or heartburn?
Will this help with lactose intolerance?
What are the most common side effects?
Is it safe to breastfeed while taking this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Beta-Gest is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Beta-Gest’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Papain
Interacts with 2 drugsPapain is a protein-digesting enzyme from the papaya plant that is used in digestive supplements and some topical products. While it has clear food and laboratory uses, strong human evidence...
Read the full Papain monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographBetaine Hydrochloride
Interacts with 36 drugsBetaine hydrochloride is a supplement used to temporarily increase stomach acid in people who may have low acid levels. Evidence for its benefits is limited and mostly based on tradition rat...
Read the full Betaine Hydrochloride monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographPectin
Interacts with 23 drugsPectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly help with cholesterol, blood sugar, and di...
Read the full Pectin monograph →Sources & How We Checked
Beta-Gest's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 28 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Papain 11 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Saf 1997;17:342-56.
- Shuttleworth D, Hill S, Marks R, Connelly DM. Relief of experimentally induced pruritus with a novel eutectic mixture of local anaesthetic agents. Br J Dermatol 1988;119:535-40.
- Mansfield LE, Ting S, Haverly RW, Yoo TJ. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge. Ann Allergy 1985;55:541-3.
- Martin, T., Uhder, K., Kurek, R., Roeddiger, S., Schneider, L., Vogt, H. G., Heyd, R., and Zamboglou, N. Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial PubMed
- Walker-Renard, P. Update on the medicinal management of phytobezoars. Am J Gastroenterol. 1993;88(10):1663-1666.
- Tymoszuk D, Wiszniewska M, Walusiak-Skorupa J. Papain-induced occupational rhinoconjunctivitis and asthma - A case report. Med Pr 2016;67(1):109-12. PubMed
- Soto-Mera MT, López-Rico MR, Filgueira JF, et al. Occupational allergy to papain. Allergy 2000;55(10):983-4. PubMed
- Tarlo SM, Shaikh W, Bell B, et al. Papain-induced allergic reactions. Clin Allergy 1978;8(3):207-15. PubMed
- Baur X, König G, Bencze K, Fruhmann G. Clinical symptoms and results of skin test, RAST and bronchial provocation test in thirty-three papain workers: Evidence for strong immunogenic potency and clinically relevant proteolytic e?ects of airborne papain. C
- Novey HS, Keenan WJ, Fairshter RD, Wells ID, Wilson AF, Culver BD. Pulmonary disease in workers exposed to papain: clinico-physiological and immunological studies. Clin Allergy 1980;10(6):721-31. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Betaine Hydrochloride 2 references
- Yago MR, Frymoyer A, Benet LZ, Smelick GS, Frassetto LA, Ding X, Dean B, Salphati L, Budha N, Jin JY, Dresser MJ, Ware JA. The use of betaine HCl to enhance dasatinib absorption in healthy volunteers with rabeprazole-induced hypochlorhydria. AAPS J. 2014 PubMed
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See these in context on the Betaine Hydrochloride monograph →
Proteolytic Enzymes (proteases) 3 references
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See these in context on the Proteolytic Enzymes (proteases) monograph →
Pectin 11 references
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- Kraut A, et al. Christmas candy maker's asthma. IgG4-mediated pectin allergy. Chest 1992;102:1605-7. PubMed
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- Albert KS, Ayres JW, DiSanto AR, et al. Influence of kaolin-pectin suspension on digoxin bioavailability. J Pharm Sci 1978;67:1582-6. PubMed
- Albert KS, Welch RD, DeSante KA, et al. Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture. J Pharm Sci 1979;68:586-8. PubMed
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).
- Washio K, Nakamura M, Sato N, et al. Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath. Allergol Int 2022;71(1):155-157. PubMed
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