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Dietary supplement

Beta Glucan 1,3D 250 mg Ingredients & Drug Interactions

by California Gold Nutrition

Beta Glucan 1,3D 250 mg label
See full label image
Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Beta Glucan 1,3D 250 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Beta Glucan 1,3D 250 mg is a dietary supplement by California Gold Nutrition with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart health, immune support.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beta-1,3 D-Glucan. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Beta Glucan 1,3D 250 mg by California Gold Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Beta Glucan 1,3D 250 mg by California Gold Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Beta Glucan 1,3D 250 mg by California Gold Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: beta-glucans derived from a source that supplies 250 mg per capsule. Beta-glucans are a type of soluble fiber found in foods like oats, barley, and certain mushrooms — they're thought to support heart health and cholesterol levels.

The capsule also contains inactive ingredients (microcrystalline cellulose, modified cellulose, magnesium stearate, and silicon dioxide) that help hold the supplement together.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Beta-glucans's overall clinical evidence instead.

Strong

Strong clinical evidence supports Beta-glucans for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Coronary heart disease (CHD) — rated "Likely Effective" (Natural Medicines).
  • On file: Dyslipidemia — rated "Likely Effective" (Natural Medicines).

Beta-glucans in this product are rated likely effective for two conditions: dyslipidemia (abnormal cholesterol and fat levels in the blood) and coronary heart disease. That means clinical evidence supports their use for these purposes.

Keep in mind that supplements work best alongside diet, exercise, and any medications your doctor has prescribed — they're not a replacement for those.

The evidence, ingredient by ingredient Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food sources are generally well tolerated by most people. Concentrated supplements like this one, though, haven't been studied as thoroughly as food amounts, so caution is advised.

When taken orally, beta-glucans seem to be well tolerated overall. In one trial of children and young adults, one patient out of 44 developed temporary elevations in liver enzymes within five days of starting a very high-dose oral beta-glucan supplement — a rare event, but worth knowing about.

There isn't enough research on supplement doses during breastfeeding, so caution is advised if you're nursing; talk with your doctor or pharmacist about what's right for you.

Side effects, ingredient by ingredient Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check your blood pressure medications (antihypertensives) — beta-glucans may lower blood pressure further, raising the risk of pressure that's too low. Also check any immunosuppressants you take, since beta-glucans may work against them.

Use the medication search tool on this page to confirm your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Beta-glucan supplements may help support heart health and cholesterol, and they're generally well tolerated. If you take blood pressure medicine or an immunosuppressant, check your specific medications with your doctor or pharmacist before starting, since beta-glucans may lower blood pressure and could interfere with immune-suppressing drugs.

If you're breastfeeding or have liver concerns, discuss this supplement with your healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beta Glucan 1,3D 250 mg, straight from the product label.

Brand California Gold Nutrition
Barcode (UPC) 898220017966
Net contents 120 Veggie Capsule(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 299584
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beta Glucan 1,3D 250 mg by California Gold Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
898220017966
IngredientAmount% DV
Beta-1,3 D-Glucan250 mg--

Other ingredients: Microcrystalline Cellulose, Modified Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: Take 2 capsules daily, with or without food. Best when taken as directed by a qualified healthcare professional.

Precautions

Warnings: Keep out of reach of children.

Pregnant or lactating women, the chronically ill, elderly, individuals under the age of 18, those taking prescription medications (e.g., blood thinners) as well as those with a physician-diagnosed medical condition should consult with a physician, pharmacist, naturopath or other qualified healthcare professional prior to taking dietary supplements.

Pregnant or lactating women, the chronically ill, elderly, individuals under the age of 18, those taking prescription medications (e.g., blood thinners) as well as those with a physician-diagnosed medical condition should consult with a physician, pharmacist, naturopath or other qualified healthcare professional prior to taking dietary supplements.

Sealed for your protection. Do not use seal is missing or broken.

This product is not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, sesame, or gluten. Produced in a third-party, audited and registered cGMP compliant facility that may process other products that contain these allergens or ingredients.

Storage

Best stored at controlled room temperature 20 degrees C to 25 degrees C (68 degrees F to 77 degrees F). Improper storage conditions, such as extended exposure to sunlight, high heat & humidity can cause product degradation over time.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

California Gold Nutrition is a registered trademark of Madre Labs, LLC

Formulated with BetaImmuneShield. BetaImmuneShield is a trademark of Vesta Nutra.

Formula

Beta Glucan 1,3D 250 mg per serving

BetaImmuneShield

Formulated with BetaImmuneShield.

Formulation

Supports healthy immune function

Formulated to contain No gluten No gmos No soy

This product is not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, sesame, or gluten.

FDA Statement of Identity

Dietary Supplement

General Statements

All California Gold Nutrition products come with a 100% GOLD guarantee. If you are not completely satisfied with your purchase, return the unused portion within 90 days for a full refund.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Beta Glucan 1,3D 250 mg by California Gold Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Beta Glucan 1,3D 250 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Beta Glucan 1,3D 250 mg by California Gold Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Beta-1,3 D-Glucan

Interacts with
293 drugs
250 mg per serving

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly low...

Beta-1,3 D-Glucan monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Modified Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beta Glucan 1,3D 250 mg by California Gold Nutrition Drug Interactions

Want to check YOUR meds against Beta Glucan 1,3D 250 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Beta-1,3 D-Glucan 293

Individual Drug Interactions

The ingredients in Beta Glucan 1,3D 250 mg interact with 293 drugs. Click any drug to see the details.

1 of the 1 ingredient in Beta Glucan 1,3D 250 mg interact with drugs. Each result below shows which ingredient is responsible. Beta-1,3 D-Glucan

Each ingredient & the kinds of drugs it affects

For each ingredient in Beta Glucan 1,3D 250 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beta-1,3 D-Glucan2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
Beta-1,3 D-Glucan full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Beta Glucan 1,3D 250 mg, from the product label.

California Gold Nutrition

See all California Gold Nutrition products
Name
Madre Labs, LLC
Street Address
301 N. Lake Ave. #500
City
Pasadena
State
CA
ZipCode
91101
Web Address
www.calgn.com
Pharmacist Counseling Corner

Beta Glucan 1,3D 250 mg by California Gold Nutrition: Common Questions

Does Beta Glucan 1,3D 250 mg by California Gold Nutrition interact with any medications?
Yes. Based on its ingredients, Beta Glucan 1,3D 250 mg has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Beta Glucan 1,3D 250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are beta-glucans and why are they in this supplement?
Beta-glucans are a type of soluble fiber naturally found in oats, barley, and mushrooms. This supplement contains them because clinical evidence shows they're likely effective for supporting healthy cholesterol levels and heart health.
Will this lower my blood pressure?
Clinical research shows that beta-glucans may reduce blood pressure in some people with high blood pressure. If you already take blood pressure medicine, talk with your doctor or pharmacist before starting this supplement, since lowering your pressure further could be risky.
Are there any common side effects?
When taken orally, beta-glucans appear to be well tolerated overall. In clinical trials, side effects were very rare — though one patient in a high-dose trial developed temporary liver enzyme elevations, which reversed on its own.
Can I take this while breastfeeding?
There isn't enough research on supplement doses during breastfeeding. Talk with your doctor or pharmacist about whether this supplement is right for you while nursing.
Does this supplement have fillers?
Yes. The capsule contains inactive ingredients like microcrystalline cellulose, modified cellulose, magnesium stearate, and silicon dioxide — these help hold the supplement together but aren't active ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beta Glucan 1,3D 250 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beta Glucan 1,3D 250 mg label
Go deeper

The Full Monographs Behind Beta Glucan 1,3D 250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beta-glucans

Interacts with 293 drugs

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...

Read the full Beta-glucans monograph →
Sources

Sources & How We Checked

Beta Glucan 1,3D 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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