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Dietary supplement

Black Cherry Extract 250 mg Ingredients & Drug Interactions

by Botanic Choice

Black Cherry Extract 250 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Black Cherry Extract 250 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Black Cherry Extract 250 mg is a dietary supplement by Botanic Choice with 1 active ingredient. Its ingredients are commonly taken for cough, bronchitis and respiratory irritation, sore throat.Based on those ingredients, 643 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Black Cherry 4:1 extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Black Cherry Extract 250 mg by Botanic Choice

Ask about any prescription or over-the-counter medication and we check it for interactions with Black Cherry Extract 250 mg by Botanic Choice — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Black Cherry Extract 250 mg by Botanic Choice

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: black cherry extract at a 4:1 concentration, delivering 250 mg per capsule. The extract is made from the wild cherry plant and is suspended in inactive ingredients including rice flour, maltodextrin, corn starch, magnesium stearate, and silicon dioxide, all held together in a gelatin capsule.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Immune and antioxidant support.
  • We looked for evidence on: Antioxidant activity, Immune function, Anti-inflammatory support.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We hold no effectiveness data for black cherry extract in our records. The facts we have don't establish whether this product works for any particular purpose.

If you're considering it for a specific health goal, that's a good question to bring to your pharmacist or doctor.

The evidence, ingredient by ingredient Wild Cherry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Wild cherry is generally considered safe in the small amounts found in commercial cough products, but there's an important caveat: the plant contains compounds that can produce cyanide in your body, especially in large doses. Orally, large amounts of wild cherry can lead to cyanide poisoning, which can be fatal.

A documented case involved a woman who consumed about 300 grams of wild cherries steeped in alcohol and developed severe symptoms including headache, nausea, vomiting, confusion, and difficulty breathing, eventually becoming comatose. The safety data advises against use during pregnancy and breastfeeding due to insufficient safety information and the cyanide risk.

Side effects, ingredient by ingredient Wild Cherry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Wild Cherry.
  • The most serious interaction on file is rated Moderate.
  • For scale: 644 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with us before taking this if you're on any medications broken down by the CYP3A4 liver enzyme—that includes cholesterol drugs, antifungals, and many others. The interaction is Moderate, and we can help you search your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may interact with hundreds of medications through a liver enzyme, though that interaction hasn't been seen in humans yet. It's not recommended during pregnancy or while breastfeeding, and large amounts carry a serious risk of cyanide toxicity.

Before starting, talk with your pharmacist about your full medication list and whether this extract makes sense for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Black Cherry Extract 250 mg, straight from the product label.

Brand Botanic Choice
Barcode (UPC) 703308029277
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2019
DSLD ID 193231
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Black Cherry Extract 250 mg by Botanic Choice, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
703308029277
IngredientAmount% DV
Black Cherry 4:1 extract250 mg--

Other ingredients: Rice Flour, Gelatin Capsule, Maltodextrin, Corn Starch, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

General Statements

Trusted since 1910 Essentials Immune & antioxidant support

Formulation

Gluten free Non GMO

Seals/Symbols

Gluten free Non GMO

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule twice daily, with food, as a dietary supplement, or as directed by a physician.

Precautions

Warning: If you are taking any medications or are pregnant or nursing do not use prior to consulting a physician.

For your protection, this container has an outer safety seal. (Do not accept if missing or broken.)

Keep out of reach of children

FDA Disclaimer Statement

This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store in a dry, cool place.

Brand IP Statement(s)

IBG Indiana Botanic Gardens

General

C-108831

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Black Cherry Extract 250 mg by Botanic Choice label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Black Cherry Extract 250 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Black Cherry Extract 250 mg by Botanic Choice

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Black Cherry 4:1 extract

Interacts with
643 drugs
250 mg per serving

Wild cherry bark is a traditional cough remedy found in many old-fashioned cough syrups and lozenges, but there is little modern scientific evidence p...

Black Cherry 4:1 extract monograph & interactions

Other (inactive) ingredients: Rice Flour, Gelatin Capsule, Maltodextrin, Corn Starch, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Black Cherry Extract 250 mg by Botanic Choice Drug Interactions

Want to check YOUR meds against Black Cherry Extract 250 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
643Drugs
643 Moderate

Ingredients driving the most interactions

Black Cherry 4:1 extract 643

Individual Drug Interactions

The ingredients in Black Cherry Extract 250 mg interact with 643 drugs. Click any drug to see the details.

1 of the 1 ingredient in Black Cherry Extract 250 mg interact with drugs. Each result below shows which ingredient is responsible. Black Cherry 4:1 extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Black Cherry Extract 250 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Black Cherry 4:1 extract1 drug type · 643 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes. Theoretically, wild cherry might increase levels of drugs metabolized by CYP3A4. However, so far, this interaction has not been reported in humans.
Some drugs metabolized by CYP3A4 include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and others.

Likelihood Possible Evidence D
Black Cherry 4:1 extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Black Cherry Extract 250 mg, from the product label.

Botanic Choice

See all Botanic Choice products
Name
Indiana Botanic Gardens, Inc.
Street Address
3401 W. 37th Ave.
City
Hobart
State
IN
ZipCode
46342
Phone Number
1-800-644-8327
Web Address
www.botanicchoice.com
Pharmacist Counseling Corner

Black Cherry Extract 250 mg by Botanic Choice: Common Questions

Does Black Cherry Extract 250 mg by Botanic Choice interact with any medications?
Yes. Based on its ingredients, Black Cherry Extract 250 mg has a known interaction with 643 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Black Cherry Extract 250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is black cherry extract safe to take every day?
The safety data on this product is limited. While small amounts in cough drops are generally considered safe, large amounts can cause cyanide toxicity, which is serious. The facts we have don't give us a clear daily limit, so talk with your pharmacist about whether this dose is appropriate for regular use.
Can I take this while I'm pregnant or breastfeeding?
No. The safety data advises against use during pregnancy—it's rated likely unsafe. There's also not enough safety information to use it while breastfeeding. Talk with your doctor about safer options.
What is black cherry extract used for?
The facts we have don't specify what health condition or symptom this product is meant to address. That's worth asking your pharmacist about so you can figure out if it's the right choice for what you're looking for.
What are the inactive ingredients in this capsule?
The inactive ingredients are rice flour, maltodextrin, corn starch, magnesium stearate, silicon dioxide, and a gelatin capsule shell. These are fillers and binders that help the capsule hold together.
How much cyanide is in one capsule of this product?
The facts we have don't give us the cyanide content per capsule, only that the plant contains cyanide-forming compounds. At 250 mg, a single capsule is likely a small amount, but we can't quantify the actual risk from one dose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Black Cherry Extract 250 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Black Cherry Extract 250 mg label
Go deeper

The Full Monographs Behind Black Cherry Extract 250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Wild Cherry

Interacts with 643 drugs

Wild cherry bark is a traditional cough remedy found in many old-fashioned cough syrups and lozenges, but there is little modern scientific evidence proving it works. The bark, leaves, and s...

Read the full Wild Cherry monograph →
Sources

Sources & How We Checked

Black Cherry Extract 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wild Cherry 4 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  4. Pentore, R., Venneri, A., and Nichelli, P. Accidental choke-cherry poisoning: early symptoms and neurological sequelae of an unusual case of cyanide intoxication. Ital.J Neurol.Sci. 1996;17(3):233-235. PubMed

See these in context on the Wild Cherry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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