Interactions on record — worth a quick check against your medications. Based on 6 of 10 ingredients. Check your meds →
Dietary supplement

Bucked Up Non-Stimulant Pink Lemonade Flavor Ingredients & Drug Interactions

by Bucked Up

Bucked Up Non-Stimulant Pink Lemonade Flavor label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bucked Up Non-Stimulant Pink Lemonade Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bucked Up Non-Stimulant Pink Lemonade Flavor is a dietary supplement by Bucked Up with 10 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sodium, Taurine, Deer Antler Velvet Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Bucked Up Non-Stimulant Pink Lemonade Flavor by Bucked Up

Ask about any prescription or over-the-counter medication and we check it for interactions with Bucked Up Non-Stimulant Pink Lemonade Flavor by Bucked Up — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Bucked Up Non-Stimulant Pink Lemonade Flavor by Bucked Up

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 10 of its 10 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains 10 active ingredients. Sodium provides electrolyte support but is present in amounts you should be mindful of if you take heart or blood pressure medications.

Beta-alanine is included for athletic performance. Vitamin B12 supports energy and nerve function.

Taurine supports heart and liver health. Citrulline malate, AlphaSize (alpha-GPC), AstraGin, Himalayan rock salt, Senactiv, and deer antler velvet extract round out the formula.

The product also contains inactive ingredients — natural flavors, silicon dioxide, calcium silicate, stevia, malic acid, citric acid, and beet juice powder — which are fillers and flavoring agents.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: pre-workout athletic performance and recovery.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle soreness, Exercise-induced muscle breakdown, Fatigue, muscle endurance, nitric oxide support — and 1 related terms.
  • The strongest evidence on file: Beta-alanine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Deer Velvet is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Fatigue.
  • Also on file: Vitamin B12 is rated "Insufficient Reliable Evidence To Rate" for Fatigue.

The evidence is mixed. Sodium is likely effective for cystic fibrosis and possibly effective for amphotericin B kidney toxicity, though for most other uses the data is not conclusive.

Beta-alanine is possibly effective for athletic and physical performance but insufficient evidence exists for cognitive decline or other uses. Vitamin B12 is effective for B12 deficiency and Imerslund-Grasbeck disease, and likely effective for cyanide poisoning.

Taurine is possibly effective for hepatitis and heart failure (congestive heart failure) but possibly ineffective for obesity. Alpha-GPC is possibly effective for Alzheimer disease but insufficient evidence exists for cognitive function and other brain conditions.

Deer velvet extract has insufficient evidence for all listed uses. For several ingredients, we simply don't have effectiveness data on file.

The evidence, ingredient by ingredient Sodium Beta-alanine Vitamin B12 Taurine Alpha-gpc Deer Velvet

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of these ingredients are generally well tolerated in typical doses. Sodium is safe in normal dietary amounts but too much is linked to high blood pressure and heart strain — avoid sodium supplements or very high intake without medical advice.

Beta-alanine commonly causes harmless tingling and flushing of the skin, usually starting on the scalp within 20 minutes and lasting about an hour; this is dose-dependent and mild to tolerable at lower doses. Taurine is generally well tolerated short-term in healthy adults, though long-term safety is less certain; it may cause constipation, diarrhea, or indigestion.

Alpha-GPC is generally well tolerated in studies, but long-term safety is not fully established, and there is a rare but serious association with stroke after 2 or more months of use. Deer velvet appears well tolerated in short-term use, but long-term safety and product quality are not well studied.

Vitamin B12 is very safe with no established upper limit. Pregnancy and breastfeeding: there is not enough safety information for beta-alanine, alpha-GPC, or deer velvet during pregnancy or breastfeeding — talk with your doctor before use.

Sodium is possibly unsafe during lactation but likely safe in pregnancy. Taurine is likely safe in pregnancy and lactation.

Vitamin B12 is safe and needed during both pregnancy and breastfeeding.

Side effects, ingredient by ingredient Sodium Beta-alanine Vitamin B12 Taurine Alpha-gpc Deer Velvet

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 6 matched ingredients can interact with medications — Deer Velvet, Vitamin B12, Taurine, Alpha-gpc, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check whether you take any antihypertensive drugs (blood pressure medications), lithium (bipolar disorder), corticosteroids, or other sodium-containing medications — sodium can reduce their effectiveness or increase sodium levels in your blood. Also double-check if you're on scopolamine patches for motion sickness, metformin for diabetes, oral contraceptives, or estrogen therapy.

Use the medication checker on this page to run your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a pre-workout powder aimed at athletic performance, but the sodium content and several moderate interactions with blood pressure, heart, and psychiatric medications mean you need to check your specific medications first. If you take antihypertensives, lithium, corticosteroids, or any sodium-sensitive medication, talk with your pharmacist before adding this to your routine.

It's not for pregnancy or breastfeeding without medical clearance.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bucked Up Non-Stimulant Pink Lemonade Flavor, straight from the product label.

Brand Bucked Up
Barcode (UPC) 851005007033
Net contents 11.3 Ounce(s); 321 Gram(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 315557
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Halal
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bucked Up Non-Stimulant Pink Lemonade Flavor by Bucked Up, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10.7 Gram(s)
Maximum serving Sizes:
10.7 Gram(s)
Servings per container
30
UPC/BARCODE
851005007033
IngredientAmount% DV
Sodium39 mg2%
Beta-Alanine2000 mg--
Vitamin B12100 mg4170%
Taurine100 mg--
Citrulline Malate6000 mg--
AlphaSize200 mg--
AstraGin25 mg--
Himalayan Rock Salt100 mg--
Senactiv25 mg--
Deer Antler Velvet Extract50 mg--

Other ingredients: Natural Flavors, Silicon Dioxide, Calcium Silicate, Stevia, Malic Acid, Citric Acid, Beet Juice, Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Pre-workout All natty Natural flavors, colors and sweeteners

Game-changing formula Das Labs presents Bucked Up, a game-changing formula set to revolutionize pre-workout. This scientifically based, non-proprietary blend with no fillers, is loaded with the most essential ingredients, including Deer Antler Velvet, to help enhance your workout. Focus Pump Strength Growth

Gainz

Formula

Bucked Up Non-Stimulant Pink Lemonade Natural flavors

Prime ingredients Citrulline Malate 2:1 - 6g to maximize blood flow (nitric oxide booster) Senactiv - Increase V02 Max & boost athletic performance Deer Antler Velvet - Supports accelerated recovery AlphaSize - Clinically shown to sharpen mental focus AstraGin - Clinically shown to increase citrulling absorption by up to 66.7% Beta-Alanine - Promotes strength, endurance, & muscle growth

Halal Islamic Services of America Iowa Since 1975 U.S.A.

Recover Deer Antler Velvet 6g pump Citrulline malate 2:1 200mg AlphaSize

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Halal Islamic Services of America Iowa Since 1975 U.S.A. Manufactured in USA Domestic & imported ingredients GMP Good Manufacturing Practice Consistent Quality

Brand IP Statement(s)

Senactiv AstraGin AlphSize Registered trademarks of NuLiv Science, USA Inc. and Chemi Nutra

Suggested/Recommended/Usage/Directions

Suggested use: Mix 1 well-rounded scoop into 6-8 oz of water 15-30 minutes prior to physical activity.

Precautions

Caution: Do not use if seal is broken or missing. Use only as directed. Discontinue use if you experience any adverse reaction.

This product is intended for healthy adults 18 and older. Keep out of reach of children.

Consult your physician prior to use if you are pregnant or nursing, taking medications, or at risk of or being treated for any medical condition.

Storage

Store in a cool, dry place.

General Statements

#Getbuckedup

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to: diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bucked Up Non-Stimulant Pink Lemonade Flavor by Bucked Up label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bucked Up Non-Stimulant Pink Lemonade Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bucked Up Non-Stimulant Pink Lemonade Flavor by Bucked Up

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size10.7 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sodium

Interacts with
205 drugs
39 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Beta-Alanine

No known
interactions
2000 mg per serving

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...

Beta-Alanine monograph & interactions

Vitamin B12

Interacts with
20 drugs
100 mg per serving Form: Methylcobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

Taurine

Interacts with
173 drugs
100 mg per serving

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements,...

Taurine monograph & interactions

Citrulline Malate

6000 mg per serving

AlphaSize

Interacts with
16 drugs
200 mg per serving Form: Alpha-Glycerylphosphorylcholine

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition...

AlphaSize monograph & interactions

AstraGin

25 mg per serving Form: Astragalus, Panax notoginseng

Himalayan Rock Salt

100 mg per serving Form: Trace Minerals

Senactiv

25 mg per serving Form: Panax notoginseng, Rosa roxburghii

Deer Antler Velvet Extract

Interacts with
52 drugs
50 mg per serving

Deer velvet is a traditional remedy made from the soft, growing antlers of deer or elk, and it is most often promoted for energy, athletic performance...

Deer Antler Velvet Extract monograph & interactions

Other (inactive) ingredients: Natural Flavors, Silicon Dioxide, Calcium Silicate, Stevia, Malic Acid, Citric Acid, Beet Juice, Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bucked Up Non-Stimulant Pink Lemonade Flavor by Bucked Up Drug Interactions

Want to check YOUR meds against Bucked Up Non-Stimulant Pink Lemonade Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
293Drugs
205 Moderate 88 Minor

Ingredients driving the most interactions

Sodium 205
Taurine 173
Deer Antler Velvet Extract 52
Vitamin B12 20
AlphaSize 16

Individual Drug Interactions

The ingredients in Bucked Up Non-Stimulant Pink Lemonade Flavor interact with 293 drugs. Click any drug to see the details.

5 of the 10 ingredients in Bucked Up Non-Stimulant Pink Lemonade Flavor interact with drugs. Each result below shows which ingredient is responsible. Sodium Taurine Deer Antler Velvet Extract Vitamin B12 AlphaSize

Each ingredient & the kinds of drugs it affects

For each ingredient in Bucked Up Non-Stimulant Pink Lemonade Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Taurine2 drug types · 173 drugs

Antihypertensive Drugs

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Some clinical evidence suggests that taurine can reduce both systolic and diastolic blood pressure.

Likelihood Probable Evidence D
Lithium

Theoretically, taurine might reduce excretion and increase plasma levels of lithium.
Taurine is thought to have diuretic properties, which might reduce the excretion of lithium.

Likelihood Probable Evidence D
Taurine full monograph & interactions

Deer Antler Velvet Extract2 drug types · 52 drugs

Contraceptive Drugs

Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Laboratory research shows that deer velvet contains small quantities of estradiol and testosterone. While clinical research shows that taking deer velvet extract does not raise testosterone levels, estradiol levels were not measured.

Likelihood Unlikely Evidence D
Estrogens

Theoretically, deer velvet might increase the effects and side effects of estrogens.
Laboratory evidence shows that deer velvet contains small quantities of estradiol and testosterone. While clinical research shows that taking deer velvet extract does not raise testosterone levels, estradiol levels were not measured.

Likelihood Unlikely Evidence D
Deer Antler Velvet Extract full monograph & interactions

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A
Vitamin B12 full monograph & interactions

AlphaSize1 drug type · 16 drugs

Scopolamine (Transderm Scop)

Theoretically, alpha-GPC might decrease the effects of scopolamine.
A small clinical study shows that alpha-GPC can partially counteract the attention and memory impairment effects caused by scopolamine given intramuscularly. Whether alpha-GPC can decrease the beneficial anti-motion sickness effects of the scopolamine patch (Transderm Scop) is unclear.

Likelihood Possible Evidence B
AlphaSize full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bucked Up Non-Stimulant Pink Lemonade Flavor, from the product label.

Bucked Up

See all Bucked Up products
Name
DAS Labs
Street Address
781 Auto Mall Dr #102
City
American Fork
State
UT
ZipCode
84003
Phone Number
855.285.2825
Web Address
Buckedup.com
Pharmacist Counseling Corner

Bucked Up Non-Stimulant Pink Lemonade Flavor by Bucked Up: Common Questions

Does Bucked Up Non-Stimulant Pink Lemonade Flavor by Bucked Up interact with any medications?
Yes. Based on its ingredients, Bucked Up Non-Stimulant Pink Lemonade Flavor has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bucked Up Non-Stimulant Pink Lemonade Flavor contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this give me the tingling feeling I've heard about with pre-workouts?
Yes, probably. Beta-alanine commonly causes a harmless pins-and-needles sensation (paresthesia) and skin flushing, usually starting on your scalp within 20 minutes of taking it and lasting about an hour. This is dose-dependent — lower doses cause it in fewer people, and it's generally mild at typical intakes.
Is there a lot of sodium in this?
The product facts don't specify the exact sodium amount per serving, but sodium is listed as an active ingredient, so it's present in meaningful quantities. If you have high blood pressure, take blood pressure meds, or have been told to watch your sodium, check the nutrition label and talk to your pharmacist before using this.
Can I take this while pregnant or breastfeeding?
There isn't enough safety information for most of the ingredients in this formula during pregnancy or breastfeeding. Beta-alanine, alpha-GPC, and deer velvet should be avoided unless your doctor says otherwise. Talk with your doctor or pharmacist before starting.
What is AlphaSize (alpha-GPC) supposed to do?
Alpha-GPC is included for brain and cognitive support. It's possibly effective for Alzheimer disease, but evidence is insufficient for other cognitive uses. It's generally well tolerated, though long-term safety isn't fully established.
Does beta-alanine actually help with workouts?
Beta-alanine is possibly effective for athletic and physical performance, according to the evidence we hold. Whether it makes a meaningful difference for your goals depends on your training, diet, and genetics.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bucked Up Non-Stimulant Pink Lemonade Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bucked Up Non-Stimulant Pink Lemonade Flavor label
Go deeper

The Full Monographs Behind Bucked Up Non-Stimulant Pink Lemonade Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Beta-alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...

Read the full Beta-alanine monograph → Herb & supplement monograph

Vitamin B12

Interacts with 20 drugs

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very helpful for people who are deficient — su...

Read the full Vitamin B12 monograph → Herb & supplement monograph

Taurine

Interacts with 173 drugs

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements, and short-term use appears generally sa...

Read the full Taurine monograph → Herb & supplement monograph

Alpha-gpc

Interacts with 16 drugs

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition in people with dementia, but evidence i...

Read the full Alpha-gpc monograph → Herb & supplement monograph

Deer Velvet

Interacts with 52 drugs

Deer velvet is a traditional remedy made from the soft, growing antlers of deer or elk, and it is most often promoted for energy, athletic performance, and joint health. Good-quality human e...

Read the full Deer Velvet monograph →
Sources

Sources & How We Checked

Bucked Up Non-Stimulant Pink Lemonade Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 108 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
  7. Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
  8. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
  9. Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
  10. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
  11. D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
  12. Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
  13. Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
  14. Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
  15. Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
  16. Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
  17. Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
  18. Moosavian SP, Haghighatdoost F, Surkan PJ, Azadbakht L. Salt and obesity: a systematic review and meta-analysis of observational studies. Int J Food Sci Nutr. 2017;68(3):265-277. PubMed
  19. O'Donnell M, Mente A, Rangarajan S, et al. Urinary sodium and potassium excretion, mortality, and cardiovascular events. N Engl J Med. 2014;371(7):612-23. DOI
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Beta-alanine 13 references
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Vitamin B12 30 references
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See these in context on the Vitamin B12 monograph →

Taurine 21 references
  1. Ahmad S, Robertson HT, Golper TA, et al. Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects. Kidney Int 1990;38:912-8. PubMed
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  3. Obermann M, Schorn CF, Mummel P, et al. Taurine induced toxic encephalopathy? Clin Neurol Neurosurg 2006;108:812-3. PubMed
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  6. Berger, A. J. and Alford, K. Cardiac arrest in a young man following excess consumption of caffeinated "energy drinks". Med J Aust. 1-5-2009;190(1):41-43. PubMed
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  18. Jang ES, Hwang SH, Kim JW, Jeong SH. Effectiveness of 4-week oral taurine treatment for muscle cramps in patients with liver cirrhosis: a single-arm pilot study. Yonsei Med J 2021;62(1):21-8. PubMed
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Alpha-gpc 4 references
  1. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to the evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res 1991;19:330-41.
  2. Barbagallo Sangiorgi G, Barbagallo M, Giordano M, et al. Alpha-glycerophosphocholine in the mental recovery of cerebral ischemic attacks: An Italian multicenter clinical trial. Ann N Y Acad Sci 1994;717:253-69. PubMed
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  4. Lee G, Choi S, Chang J, et al. Association of L-a glycerylphosphorylcholine with subsequent stroke risk after 10 Years. JAMA Netw Open 2021;4(11):e2136008.

See these in context on the Alpha-gpc monograph →

Deer Velvet 2 references
  1. Sleivert, G., Burke, V., Palmer, C., Walmsley, A., Gerrard, D., Haines, S., and Littlejohn, R. The effects of deer antler velvet extract or powder supplementation on aerobic power, erythropoiesis, and muscular strength and endurance characteristics. Int PubMed
  2. Bubenik, G. A., Miller, K. V., Lister, A. L., Osborn, D. A., Bartos, L., and van der Kraak, G. J. Testosterone and estradiol concentrations in serum, velvet skin, and growing antler bone of male white-tailed deer. J Exp Zoolog.A Comp Exp Biol 3-1-2005;30 PubMed

See these in context on the Deer Velvet monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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