Interactions on record — worth a quick check against your medications. Based on 6 of 8 ingredients. Check your meds →
Dietary supplement

Bulasterone 1550 mg Ingredients & Drug Interactions

by Hi-Tech Pharmaceuticals

Bulasterone 1550 mg label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bulasterone 1550 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bulasterone 1550 mg is a dietary supplement by Hi-Tech Pharmaceuticals with 8 active ingredients. Its ingredients are commonly taken for anti-aging and low dhea levels, mood and depression, vaginal dryness and sexual health.Based on those ingredients, 1,149 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bulbine Natalensis 100:1 Extract, Dehydroepiandrosterone, Tribulus Terrestris Extract 90% Steroidal Saponins. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Bulasterone 1550 mg by Hi-Tech Pharmaceuticals

Ask about any prescription or over-the-counter medication and we check it for interactions with Bulasterone 1550 mg by Hi-Tech Pharmaceuticals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Bulasterone 1550 mg by Hi-Tech Pharmaceuticals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 8 active ingredients.
  • “Rapid Release Testosterone Booster” is listed as a grouped ingredient — the label gives one combined amount (1,550 mg) without saying how much of each component you get.

Bulasterone contains 8 ingredients, most of them designed to raise testosterone or support muscle and sexual function. The main active ingredients are DHEA (a hormone precursor), Sodium D-Aspartic Acid (an amino acid), Bulbine Natalensis extract (a plant used traditionally for sexual function), Tribulus Terrestris extract (another plant with steroidal compounds), Rhaponticum Carthamoides (also called maral root, used for athletic performance), Quebracho Blanco extract, 25R Spirostan-5a-diol-6-one-3-one Decanoate, and 5-Methyl-7-Methoxyflavone.

The product also includes a blend labeled "Rapid Release Testosterone Booster" whose specific components are listed separately. Inactive ingredients include microcrystalline cellulose, dicalcium phosphate, and several other binders and colorants.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: increase muscular development and strength gains.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Male infertility, Muscle strength, Physical performance, Muscle hypertrophy — and 3 related terms.
  • The strongest evidence on file: Dhea is rated "Possibly Effective" for Infertility (Natural Medicines).
  • Also on file: Tribulus is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Dhea is rated "Possibly Ineffective" for Muscle strength, Physical performance.

DHEA is rated likely effective for vaginal atrophy and possibly effective for infertility, aging skin, and depression — though the evidence for those last three remains incomplete. Tribulus terrestris is rated possibly effective for sexual dysfunction but possibly ineffective for athletic performance, and we lack strong evidence for its use in benign prostatic hyperplasia.

Bulbine natalensis, Rhaponticum carthamoides, and Quebracho Blanco all lack sufficient evidence in our data to rate their effectiveness for the conditions they're marketed for. Sodium D-Aspartic Acid is rated likely effective only for cystic fibrosis and possibly effective for amphotericin B nephrotoxicity — not for the testosterone or sexual function claims on this product's label.

We held no effectiveness ratings for 25R Spirostan-5a-diol-6-one-3-one Decanoate or 5-Methyl-7-Methoxyflavone.

The evidence, ingredient by ingredient Dhea Sodium Bulbine Natalensis Tribulus Maral Root Quebracho Blanco

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

DHEA is generally well tolerated at typical doses short-term, but long-term oral use may carry a higher cancer risk — something to discuss with your doctor. The most common side effects are acne (especially in women), headache, insomnia, mood changes, and nausea.

Women may experience masculinization (voice deepening, increased genital size, irregular periods, oily skin, reduced breast size, abnormal hair growth). Men may report aggression and breast tenderness.

DHEA-induced mood swings, mania, anxiety, irritability, and depression have also been reported. Sodium D-Aspartic Acid in high amounts is linked to high blood pressure, heart strain, and kidney disease; normal dietary sodium is fine, but supplements or very high intake need medical oversight.

Bulbine natalensis has limited human safety data and animal studies suggest possible liver and kidney toxicity at higher doses; it may also contain high levels of aluminum and iron, raising concerns about cognition and gastric problems. Tribulus is often well tolerated short-term but long-term and quality safety data are sparse; rare serious side effects include liver and kidney injury, seizures, and chronic painful erection.

Quebracho Blanco is generally well tolerated but can cause headache, vertigo, drowsiness, salivation, and in large doses nausea and vomiting.

Side effects, ingredient by ingredient Dhea Sodium Bulbine Natalensis Tribulus Maral Root Quebracho Blanco

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 6 matched ingredients can interact with medications — Tribulus, Dhea, Maral Root, Sodium, Bulbine Natalensis.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 1,150 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against these drug types before taking this product. Most critical: antidepressants (moderate risk of psychiatric effects including mania), blood thinners and antiplatelet drugs (moderate bleeding risk from DHEA and Bulbine), blood pressure medications (moderate — tribulus and sodium may lower pressure further), and diabetes medications (moderate — tribulus may lower blood sugar further).

Also check: drugs metabolized by the liver (CYP3A4, CYP1A2, CYP2C9 pathways — DHEA and Bulbine may reduce their levels), corticosteroids and lithium (sodium content), cancer medications targeting estrogen (DHEA can counteract them), and digoxin (heart medication — Bulbine may increase its toxicity). Use the search tool on this page to match your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a hormone and botanical blend designed for testosterone support and sexual function, but it's not for everyone. It's best suited for adult males with medical oversight, especially because DHEA is a hormone with real side effects and many documented drug interactions.

If you take any prescription medication — particularly antidepressants, blood thinners, blood pressure drugs, diabetes medications, or cancer drugs — talk with your pharmacist or doctor before starting. Women and anyone pregnant or breastfeeding should avoid it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bulasterone 1550 mg, straight from the product label.

Brand Hi-Tech Pharmaceuticals
Barcode (UPC) 85708400099
Net contents 150 ct
Market status Off market
Date entered into DSLD Mar 25, 2014
DSLD ID 31610
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bulasterone 1550 mg by Hi-Tech Pharmaceuticals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
3 Tablet(s)
Servings per container
50
UPC/BARCODE
85708400099
IngredientAmount% DV
Dehydroepiandrosterone0 NP--
Rapid Release Testosterone Booster1550 mg--
Sodium D-Aspartic Acid0 NP--
Bulbine Natalensis 100:1 Extract0 NP--
Tribulus Terrestris Extract 90% Steroidal Saponins0 NP--
Rhaponticum Carthamoides 98% Extract0 NP--
25R Spirostan-5a-diol-6-one-3-one Decanoate0 NP--
5-Methyl-7-Methoxyflavone0 NP--
Quebracho Blanco extract0 NP--

Other ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Sodium Starch Glycolate, Dextrose, Stearic Acid, Magnesium Stearate, Triacetin, Titanium Dioxide, FD&C Blue #1, FD&C Red #40

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

HI-TECH PHARMACEUTICALS HTP

FDA Statement of Identity

DIETARY SUPPLEMENT

General Statements

Revolutionary New Anabolic Agent Designed to Increase Muscular Development & Strength Gains! World's Strongest Testosterone Booster!

(WARNINGS/INFORMATION CONTINUED ON BACK OF LABEL)

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1-3 tablets in the morning and 1-3 tablets after lunch or prior to training. Do not exceed 9 tablets daily. If the initial dosage is too intense, reduce to 4 tablets daily.

FDA Disclaimer Statement

THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.

Precautions

WARNING: NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 18 YEARS.

DO NOT USE IF PREGNANT OR NURSING.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bulasterone 1550 mg by Hi-Tech Pharmaceuticals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bulasterone 1550 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bulasterone 1550 mg by Hi-Tech Pharmaceuticals

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Rapid Release Testosterone Booster

1550 mg per serving

Other (inactive) ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Sodium Starch Glycolate, Dextrose, Stearic Acid, Magnesium Stearate, Triacetin, Titanium Dioxide, FD&C Blue #1, FD&C Red #40. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bulasterone 1550 mg by Hi-Tech Pharmaceuticals Drug Interactions

Want to check YOUR meds against Bulasterone 1550 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,149Drugs
1,145 Moderate 4 Minor

Ingredients driving the most interactions

Bulbine Natalensis 100:1 Extract 919
Dehydroepiandrosterone 776
Tribulus Terrestris Extract 90% Steroidal Saponins 259
Sodium D-Aspartic Acid 205
Rhaponticum Carthamoides 98% Extract 122

Individual Drug Interactions

The ingredients in Bulasterone 1550 mg interact with 1,149 drugs. Click any drug to see the details.

5 of the 8 ingredients in Bulasterone 1550 mg interact with drugs. Each result below shows which ingredient is responsible. Bulbine Natalensis 100:1 Extract Dehydroepiandrosterone Tribulus Terrestris Extract 90% Steroidal Saponins Sodium D-Aspartic Acid Rhaponticum Carthamoides 98% Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Bulasterone 1550 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bulbine Natalensis 100:1 Extract7 drug types · 919 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, combining Bulbine natalensis leaf with drugs that have anticoagulant or antiplatelet activity might increase the risk of bruising and bleeding.
In vitro research shows that Bulbine natalensis ground leaf extract inhibits platelet aggregation.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Bulbine natalensis stem might reduce the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that Bulbine natalensis stem extract slightly induces CYP1A2 mRNA expression and enzyme activity. Theoretically, this may increase the metabolism of CYP1A2 substrates; however, this has not been studied in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, Bulbine natalensis stem might reduce the levels and clinical effects of CYP2C9 substrates.
In vitro research shows that Bulbine natalensis stem extract induces CYP2C9 mRNA expression and enzyme activity. Theoretically, this may increase the metabolism of CYP2C9 substrates; however, this has not been studied in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, Bulbine natalensis stem might reduce the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Bulbine natalensis stem extract induces CYP3A4 mRNA expression and enzyme activity. Theoretically, this may increase the metabolism of CYP3A4 substrates, but this has not been studied in humans.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, Bulbine natalensis stem might increase the risk of adverse effects and toxicity when taken with digoxin.
Bulbine natalensis stem may contain cardiac glycosides, although it is unclear if these chemicals are present in clinically relevant concentrations.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

Theoretically, Bulbine natalensis stem might increase the levels and clinical effects of p-glycoprotein substrates.
In vitro research shows that Bulbine natalensis stem extract induces p-glycoprotein mRNA expression; however, effects on transporter expression were not evaluated.

Likelihood Possible Evidence D
Testosterone

Theoretically, using Bulbine natalensis stem with testosterone replacement therapy might increase the risk of adverse effects.
Animal research shows that Bulbine natalensis stem can increase testosterone levels.

Likelihood Possible Evidence D
Bulbine Natalensis 100:1 Extract full monograph & interactions

Dehydroepiandrosterone10 drug types · 776 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, DHEA might increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Human and laboratory research show that DHEA and DHEA-S can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidepressant Drugs

Theoretically, DHEA might increase the risk of psychiatric adverse events when used with antidepressants.
In a human case report, the use of a selective serotonin reuptake inhibitor (SSRI) with DHEA caused a manic episode. Concern for this interaction may be greater in younger individuals with higher baseline DHEA levels.

Likelihood Possible Evidence D
Aromatase Inhibitors

Theoretically, DHEA might interfere with the clinical effects of aromatase inhibitors.
DHEA is a potent estrogen agonist, which may antagonize the anti-estrogen activity of aromatase inhibitors.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Some preliminary evidence shows that DHEA may inhibit CYP3A4; however, the clinical significance of this potential interaction is not known.

Likelihood Possible Evidence D
Fulvestrant (Faslodex)

Theoretically, DHEA might interfere with the anti-estrogen effects of fulvestrant.
DHEA is a potent estrogen agonist. Some research shows that it can overcome the estrogen receptor antagonist action of fulvestrant in estrogen-receptor positive cancer cells.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, DHEA might interfere with the anti-estrogen effects of tamoxifen.
DHEA is a potent estrogen agonist. Some research shows that it can overcome the estrogen receptor antagonist activity of tamoxifen in estrogen-receptor positive cancer cells.

Likelihood Possible Evidence D
Triazolam (Halcion)

DHEA can increase blood levels of triazolam.
Administration of DHEA 200 mg daily for two weeks was shown to inhibit the cytochrome P450 3A4 (CYP3A4) metabolism of triazolam. This inhibition appears to be due to DHEA-S, rather than DHEA.

Likelihood Probable Evidence D
Tuberculosis Vaccine

DHEA might reduce the effectiveness of the tuberculosis vaccine.
Animal research shows that high doses of DHEA can reduce the efficacy of the Bacillus Calmette-Guérin (BCG) tuberculosis vaccine.

Likelihood Possible Evidence D
Estrogens

Theoretically, DHEA might increase the effects and adverse effects of estrogen therapy.
DHEA is a precursor to estrogen and androgen and is metabolized into those substances. In clinical research, DHEA supplements increase the levels of these hormones. Also, in clinical research, estrogen-progestin oral contraceptives and conjugated estrogens reduce blood levels of DHEA and DHEA-S. The clinical significance of these findings is unclear.

Likelihood Possible Evidence D
Testosterone

Theoretically, DHEA might increase the effects and side effects of testosterone therapy.
DHEA is a precursor to estrogen and androgen and is metabolized into those substances. In clinical research, DHEA supplements increase the levels of these hormones. The clinical significance of these findings is unclear.

Likelihood Possible Evidence D
Dehydroepiandrosterone full monograph & interactions

Tribulus Terrestris Extract 90% Steroidal Saponins3 drug types · 259 drugs

Antidiabetes Drugs

Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.

Likelihood Possible Evidence D
Lithium

Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Tribulus Terrestris Extract 90% Steroidal Saponins full monograph & interactions

Sodium D-Aspartic Acid7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium D-Aspartic Acid full monograph & interactions

Rhaponticum Carthamoides 98% Extract1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

In vitro research shows that maral root tincture can reduce platelet aggregation. Theoretically, maral root might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs. Some of these drugs include aspirin, clopidogrel (Plavix), nonsteroidal anti-inflammatory drugs (NSAIDs) such as diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

Likelihood Possible Evidence D
Rhaponticum Carthamoides 98% Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bulasterone 1550 mg, from the product label.

Hi-Tech Pharmaceuticals

See all Hi-Tech Pharmaceuticals products
Name
Hi-Tech Pharmaceuticals, Inc.
Street Address
6015-B Unity Dr.
City
Norcross
State
GA
ZipCode
30071
Phone Number
1-888-855-7919
Web Address
www.hitechpharma.com
Pharmacist Counseling Corner

Bulasterone 1550 mg by Hi-Tech Pharmaceuticals: Common Questions

Does Bulasterone 1550 mg by Hi-Tech Pharmaceuticals interact with any medications?
Yes. Based on its ingredients, Bulasterone 1550 mg has a known interaction with 1,149 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bulasterone 1550 mg contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is DHEA a hormone, and is it safe to take long-term?
Yes, DHEA is a hormone precursor. It's generally well tolerated short-term at typical doses, but there's concern that long-term use may raise cancer risk. Because it's a hormone, it should only be used under medical guidance and with regular monitoring.
Can women take this product?
Women can experience masculinization side effects including voice deepening, increased genital size, irregular periods, oily skin, reduced breast size, and abnormal hair growth. The data advises against DHEA during pregnancy and breastfeeding. Any woman considering this should talk with her doctor first.
What's the most common side effect?
Acne is the most commonly reported side effect, especially in women, though it's usually mild and may improve by lowering the dose. Headache, insomnia, mood changes, and nausea are also common.
Does this product actually boost testosterone?
DHEA is rated possibly effective for infertility and possibly effective for sexual dysfunction, but we lack strong evidence that sodium D-aspartic acid or the plant extracts actually raise testosterone in humans. The evidence for athletic performance is lacking or shows it may not work.
What if I'm on a blood thinner like warfarin or aspirin?
Both DHEA and Bulbine natalensis can inhibit platelet clotting, which may increase bleeding risk on top of your blood thinner. Do not start this product without checking with your pharmacist or doctor first.
Why do I need to check my antidepressant?
DHEA has a documented case of triggering a manic episode when used with an SSRI antidepressant. While it's a rare interaction, the risk is real and may be higher in younger people, so it's important to get clearance from your prescriber.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bulasterone 1550 mg label
Go deeper

The Full Monographs Behind Bulasterone 1550 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Dhea

Interacts with 776 drugs

DHEA is a natural hormone that the body makes and that declines with age, and it is sold as a supplement claiming many benefits. The evidence is mixed and limited for most uses, and because...

Read the full Dhea monograph → Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Bulbine Natalensis

Interacts with 919 drugs

Bulbine natalensis is a South African plant marketed mainly as a testosterone-boosting and libido supplement, but the human evidence is essentially absent and most claims come from animal st...

Read the full Bulbine Natalensis monograph → Herb & supplement monograph

Tribulus

Interacts with 259 drugs

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims is weak and inconsistent. It is general...

Read the full Tribulus monograph → Herb & supplement monograph

Maral Root

Interacts with 122 drugs

Maral Root (Rhaponticum carthamoides) is a Siberian herb used as an 'adaptogen' and is popular among athletes for stamina and muscle building, largely because it contains plant compounds cal...

Read the full Maral Root monograph → Herb & supplement monograph

Quebracho Blanco

Quebracho Blanco is the bark of a South American tree traditionally used for breathing problems and coughs, but high-quality human studies are lacking. It contains alkaloids that may affect...

Read the full Quebracho Blanco monograph →
Sources

Sources & How We Checked

Bulasterone 1550 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 157 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Dhea 98 references
  1. Frye RF, Kroboth PD, Folan MM, et al. Effect of DHEA on CYP3A-mediated metabolism of triazolam. Clin Pharmacol Ther 2000;67:109 (abstract PI-82).
  2. Kuritzky L. DHEA: Science or wishful thinking? Hosp Pract 1998;33:85-6. PubMed
  3. Van Vollenhoven RF, Morabito LM, Engleman EG, et al. Treatment of systemic lupus erythematosus with dehydroepiandrosterone: 50 patients treated up to 12 months. J Rheumatol 1998;25:285-9.
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See these in context on the Sodium monograph →

Bulbine Natalensis 8 references
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  8. Husain I, Dale OR, Manda V, et al. Bulbine natalensis (currently Bulbine latifolia) and select bulbine knipholones modulate the activity of AhR, CYP1A2, CYP2B6, and P-gp. Planta Med 2022;88(12):975-984. PubMed

See these in context on the Bulbine Natalensis monograph →

Tribulus 10 references
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See these in context on the Tribulus monograph →

Maral Root 2 references
  1. Koleckar V, Brojerova E, Rehakova Z, et al. In vitro antiplatelet activity of flavonoids from Leuzea carthamoides. Drug Chem Toxicol 2008;31(1):27-35.
  2. Ryan ED, Gerstner GR, Mota JA, et al. The Acute Effects of a Multi-Ingredient Herbal Supplement on Performance Fatigability: A Double-Blind, Randomized, and Placebo-Controlled Trial. J Diet Suppl 2021;18(5):507-516. PubMed

See these in context on the Maral Root monograph →

Quebracho Blanco 1 reference
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

See these in context on the Quebracho Blanco monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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