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Dietary supplement

Burdock Root 425 mg Ingredients & Drug Interactions

by Herbal Secrets

Burdock Root 425 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Burdock Root 425 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Burdock Root 425 mg is a dietary supplement by Herbal Secrets with 1 active ingredient. Its ingredients are commonly taken for skin conditions like acne and eczema, digestive support, diuretic ('detox') and blood purifier.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Burdock. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Burdock Root 425 mg by Herbal Secrets

Ask about any prescription or over-the-counter medication and we check it for interactions with Burdock Root 425 mg by Herbal Secrets — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Burdock Root 425 mg by Herbal Secrets

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Burdock Root 425 mg is a single-ingredient supplement: each capsule contains 425 mg of burdock root powder. The capsule itself is made from gelatin, with magnesium stearate added as a processing aid.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: blood detoxification and circulation support.
  • We looked for evidence on: blood purification, internal heat, inflammatory conditions.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for burdock in treating acne, aging skin, breast cancer, common cold, or eczema is insufficient — we don't have enough reliable data to say whether it works for any of these uses. If you're considering it for one of these conditions, talk with your doctor about what the current science actually supports.

The evidence, ingredient by ingredient Burdock

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Burdock is generally well tolerated when eaten as food and used short-term in healthy adults, though human safety data are limited. Serious allergic reactions including anaphylaxis are rare but documented.

Contact dermatitis has been reported, especially with prolonged use of burdock root oil or plasters — some people developed rash and irritation within a week of application. One case of liver injury was reported in someone using a multi-ingredient detox tea containing burdock, but it's unclear whether burdock was responsible.

The safety data advises against medicinal amounts during pregnancy due to lack of safety information and possible effects on the uterus. There isn't enough data to know whether it's safe while breastfeeding — talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Burdock

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Burdock.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before combining this with blood thinners (anticoagulants) or antiplatelet drugs — burdock may theoretically increase bleeding risk with these medications. No other medication types are documented to interact in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Burdock Root may be worth considering if you're interested in herbal supplements and don't take blood thinners, but the evidence for it treating common skin or health concerns is weak. If you take any anticoagulant or antiplatelet medication, check your specific drugs with your pharmacist before starting.

Pregnant people and those breastfeeding should talk with their doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Burdock Root 425 mg, straight from the product label.

Brand Herbal Secrets
Barcode (UPC) 810180027144
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 282817
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Burdock Root 425 mg by Herbal Secrets, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
180
UPC/BARCODE
810180027144
IngredientAmount% DV
Burdock425 mg--

Other ingredients: Gelatin, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Burdock Root has been valued for thousands of years for its ability to purify blood and cool internal heat. It has potent anti-inflammatory and antibacterial effects on the body. Herbal Secrets Burdock Root supports detoxification, which helps to improve organ health and overall well-being. Burdock Root also promote blood circulation which may help to improve skin health and over well-being.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, adults take one (1) to two (2) capsules daily, preferably with meals or as directed by a healthcare professional. (Capsules may be opened and prepared as a tea.)

Precautions

Caution: Not intended for use by person under the age of 18.

If you are pregnant, nursing, taking any medication(s) or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children,

Do not use if safety seal is damaged or missing,

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Natural Dietary Supplement

Formulation

Herbal Remedy Promotes Blood Detoxification Promotes Healthy Circulation Supports Overall Health & Well-being

Contains No: Artificial Color, Flavor, Sweetener, Preservatives, Sugar, Starch, Milk, Lactose, Gluten, Wheat, Yeast, Fish or Sodium

100% natural

Seals/Symbols

GMP Good Manufacturing Practice Quality Product

Made in the USA

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Burdock Root 425 mg by Herbal Secrets label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Burdock Root 425 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Burdock Root 425 mg by Herbal Secrets

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

Burdock

Interacts with
122 drugs
425 mg per serving Form: Arctium lappa

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and mo...

Burdock monograph & interactions

Other (inactive) ingredients: Gelatin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Burdock Root 425 mg by Herbal Secrets Drug Interactions

Want to check YOUR meds against Burdock Root 425 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Burdock 122

Individual Drug Interactions

The ingredients in Burdock Root 425 mg interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Burdock Root 425 mg interact with drugs. Each result below shows which ingredient is responsible. Burdock

Each ingredient & the kinds of drugs it affects

For each ingredient in Burdock Root 425 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Burdock1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

In vitro research shows that lignans from burdock reduce rabbit platelet aggregation by inhibiting platelet activating factor. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Burdock full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Burdock Root 425 mg, from the product label.

Herbal Secrets

See all Herbal Secrets products
Name
Herbal Secrets
Street Address
629 Grove Street
City
Jersey City
State
NJ
ZipCode
07310
Web Address
amazingnutrition.com
Pharmacist Counseling Corner

Burdock Root 425 mg by Herbal Secrets: Common Questions

Does Burdock Root 425 mg by Herbal Secrets interact with any medications?
Yes. Based on its ingredients, Burdock Root 425 mg has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Burdock Root 425 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Burdock Root if I'm on warfarin or another blood thinner?
Not without checking first. Burdock may increase bleeding risk when combined with anticoagulants or antiplatelet drugs. Talk with your pharmacist about your specific medication before starting this supplement.
Is Burdock Root safe to use long-term?
The safety data are limited. It's considered likely safe as a food and for short-term use in healthy adults, but we don't have enough information about long-term supplemental use. If you're thinking of taking it regularly, discuss that with your doctor.
Can I take this while pregnant?
The safety data advise against medicinal amounts during pregnancy due to lack of safety information and possible effects on the uterus. Talk with your doctor before taking it.
Is it safe while breastfeeding?
There isn't enough data to know whether it's safe while breastfeeding. Talk with your pharmacist or doctor for personalized advice.
Does Burdock Root actually work for acne or eczema?
The evidence isn't established in our data — we don't have enough reliable information to say it works for either condition. If you're considering it for skin health, check with your doctor about other options with stronger evidence.
What are the side effects?
Burdock is generally well tolerated. Serious allergic reactions are rare but possible, including rash and anaphylaxis. Contact dermatitis has been reported, especially with prolonged use of burdock oil or plasters. If you notice rash, itching, or swelling, stop and contact your doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Burdock Root 425 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Burdock Root 425 mg label
Go deeper

The Full Monographs Behind Burdock Root 425 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Burdock

Interacts with 122 drugs

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and most claims are not well proven. It is wid...

Read the full Burdock monograph →
Sources

Sources & How We Checked

Burdock Root 425 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Burdock 11 references
  1. Iwakami S, Wu JB, Ebizuka Y, Sankawa U. Platelet activating factor (PAF) antagonists contained in medicinal plants: lignans and sesquiterpenes. Chem Pharm Bull (Tokyo) 1992;40:1196-8. PubMed
  2. Sasaki Y, Kimura Y, Tsunoda T, Tagami H. Anaphylaxis due to burdock. Int J Dermatol 2003;42:472-3. PubMed
  3. Rhoads PM, Tong TG, Banner W Jr, Anderson R. Anticholinergic poisonings associated with commercial burdock root tea. J Toxicol Clin Toxicol 1984-85;22:581-4. PubMed
  4. Rodriguez P, Blanco J, Juste S, et al. Allergic contact dermatitis due to burdock (Arctium lappa). Contact Dermatitis 1995;33:134-5.
  5. Kassler, W. J., Blanc, P., and Greenblatt, R. The use of medicinal herbs by human immunodeficiency virus-infected patients. Arch Intern Med 1991;151(11):2281-2288. DOI
  6. Chan, Y. S., Cheng, L. N., Wu, J. H., Chan, E., Kwan, Y. W., Lee, S. M., Leung, G. P., Yu, P. H., and Chan, S. W. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 2011;19(5):245-254. PubMed
  7. Breed, F. B. and Kuwabara, T. Burdock ophthalmia. Arch Ophthalmol 1966;75(1):16-20.
  8. Bryson, P. D., Watanabe, A. S., Rumack, B. H., and Murphy, R. C. Burdock root tea poisoning. Case report involving a commercial preparation. JAMA 5-19-1978;239(20):2157. DOI
  9. <p>Fletcher GF<span>, </span>Cantwell JD. Burdock root tea poisoning. JAMA <span>1978 Oct 6;240(15):1586.</span></p> DOI
  10. Latif A, Fichadiya H, Abid F, Capo G. Herbal Teas and Thrombocytopenia: A Curious Case of Yellow Dock and Burdock-Induced Thrombocytopenia. Eur J Case Rep Intern Med 2022;9(3):003247. PubMed
  11. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed

See these in context on the Burdock monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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