Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Calm Wind Teapills Ingredients & Drug Interactions

by Plum Flower

Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Calm Wind Teapills is a dietary supplement by Plum Flower with 4 active ingredients. Its ingredients are commonly taken for source of vitamin c, digestive support, aromatherapy and relaxation.Based on those ingredients, 813 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Paeonia lactiflora Root Extract, Atractylodes macrocephala rhizome extract, Citrus reticulata Peel Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Calm Wind Teapills by Plum Flower

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Proprietary Extract Blend” is a proprietary blend — the label gives one combined amount (1,360 mg) without saying how much of each component you get.

Calm Wind Teapills contains 4 active ingredients in a proprietary blend, plus inactive ingredients (magnesium silicate, activated carbon, maltose, and china wax) that help hold the pill together. The blend includes citrus reticulata (tangerine) peel extract, paeonia lactiflora (peony) root extract, saposhnikovia divaricata root extract, and atractylodes macrocephala rhizome extract — traditional herbs used in Chinese medicine formulas.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

Our data don't establish that any of the active ingredients in this product are effective for a specific condition. Tangerine peel extract has been studied for cancer but the evidence is insufficient to draw conclusions.

Peony root, atractylodes, and saposhnikovia have similarly insufficient evidence for the conditions they're traditionally used for — ranging from migraine and fatigue to anorexia and colds. If you're considering this product, talk with your pharmacist about what you're hoping it will do.

The evidence, ingredient by ingredient Tangerine Peony Atractylodes

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Peony root is generally well tolerated in the short term, though high-quality safety data are limited. The most common side effects reported are gastrointestinal — abdominal bloating, loss of appetite, diarrhea, and nausea — with diarrhea appearing in a small number of trial participants.

Tangerine peel extract is safe when you eat the fruit as food, but concentrated extracts should be used cautiously under medical guidance. Atractylodes has limited human safety data; the most common reported side effects are allergic reaction, dry mouth, and nausea.

Peony and atractylodes are not recommended during pregnancy or breastfeeding due to insufficient safety data.

Side effects, ingredient by ingredient Tangerine Peony Atractylodes

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Peony, Atractylodes, Tangerine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 814 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check these medication types with the search tool: blood thinners and antiplatelet drugs (moderate concern), birth control and estrogen therapy (moderate concern), and any medications that your liver metabolizes, especially CYP3A4 and CYP1A2 substrates, including clozapine, phenytoin, and aromatase inhibitors (moderate to minor concern). Worst severity is Moderate.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Calm Wind Teapills is a traditional Chinese herbal blend with limited human evidence for its intended effects. If you take any prescription medications — especially blood thinners, birth control, antipsychotics, anti-seizure drugs, or hormone therapy — you need to check your specific drugs with the tool on this page before starting.

Pregnant women and those breastfeeding should avoid it. Talk with your pharmacist about whether this is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Calm Wind Teapills, straight from the product label.

Brand Plum Flower
Barcode (UPC) 739934860267
Net contents 200 Pill(s); 1.2 Ounce(s); 34 Gram(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 336448
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Calm Wind Teapills by Plum Flower, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
8 Pill(s)
Maximum serving Sizes:
8 Pill(s)
Servings per container
25
UPC/BARCODE
739934860267
IngredientAmount% DV
Proprietary Extract Blend1360 mg--
Citrus reticulata Peel Extract0 NP--
Paeonia lactiflora Root Extract0 NP--
Saposhnikovia divaricata Root Extract0 NP--
Atractylodes macrocephala rhizome extract0 NP--

Other ingredients: Magnesium Silicate, Hydrated, Carbon, Activated, Maltose, China Wax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Tong Xie Yao Fang Wan

Foci Pharmaceutical 1929 US owned & operated since 1969.

FDA Statement of Identity

Herbal Supplement

Precautions

Contains wheat (processed with wheat bran)

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Take 8 pills 3 times daily or as directed by your health care practitioner.

Seals/Symbols

Plum Flower Guarantee Sourced sustainably FDA Registered cGMP Compliant Made in a cGMP Certified Facility Lab Tested Quality Verified Species Verified

Formulation

Made in China in partnership with Lanzhou Foci Pharmaceutical Co. Ltd.

See for yourself

Calm Wind Teapills by Plum Flower label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Calm Wind Teapills by Plum Flower

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size8 Pill(s) Dosage formTablet Or Pill Servings per container25 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Extract Blend

1360 mg per serving

Other (inactive) ingredients: Magnesium Silicate, Hydrated, Carbon, Activated, Maltose, China Wax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Calm Wind Teapills by Plum Flower Drug Interactions

Want to check YOUR meds against Calm Wind Teapills?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
813Drugs
813 Moderate

Each ingredient & the kinds of drugs it affects

For each ingredient in Calm Wind Teapills with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Paeonia lactiflora Root Extract7 drug types · 811 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research suggests that peony might have antiplatelet, anticoagulant, and antithrombotic effects.

Likelihood Possible Evidence D
Clozapine (Clozaril)

Theoretically, peony might increase the levels and clinical effects of clozapine.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on cytochromes P450 (CYP) 1A2 and CYP3A4. This effect has not been reported in humans.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, peony might interfere with contraceptive drugs due to competition for estrogen receptors.
In vitro and animal research shows that peony extract has estrogenic activity. Concomitant use might also increase the risk for estrogen-related adverse effects.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, concomitant use of large amounts of peony might interfere with hormone replacement therapy and/or increase the risk for estrogen-related adverse effects.
In vitro and animal research shows that peony extract has estrogenic activity. Theoretically, peony might compete for estrogen receptors and/or cause additive estrogenic effects.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

Theoretically, peony might reduce the levels and clinical effects of phenytoin.
Animal research shows that taking peony root reduces levels of phenytoin. Some researchers suggest that peony root might affect cytochrome P450 (CYP) 2C9, which metabolizes phenytoin. However, preliminary research in humans shows that peony root does not alter levels of losartan (Cozaar), which is also metabolized by CYP2C9.

Likelihood Probable Evidence D

Atractylodes macrocephala rhizome extract5 drug types · 801 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Laboratory research suggests that atractylenolides II and III, constituents of atractylodes, reduce platelet activation. So far, this has not been shown in humans.

Likelihood Possible Evidence D
Aromatase Inhibitors

Theoretically, atractylodes may have an additive effect when used with other aromatase inhibitors.
Laboratory research suggests that atractylodes and its constituents exhibit aromatase inhibitor effects.

Likelihood Possible Evidence D
Hexobarbital

Theoretically, taking atractylodes may prolong the therapeutic and adverse effects of hexobarbital.
In animals, atractylodes has been shown to prolong the effects of hexobarbital. These effects have not been shown in humans.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
In animals, atractylodes administered at high doses has been shown to induce CYP1A2 activity. This effect has not been shown in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
In animals, atractylodes administered at high doses has been shown to inhibit CYP3A1 activity, which is a homolog to the human CYP3A4 enzyme. This effect has not been shown in humans.

Likelihood Possible Evidence D

Citrus reticulata Peel Extract2 drug types · 643 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4). This suggests that tangeretin may stimulate CYP3A4 activity. However, in humans, drinking tangerine juice 200 mL slightly delayed the absorption, but did not affect the metabolism, of midazolam, a CYP3A4 substrate. Theoretically, tangerine juice might increase CYP3A4 activity and decrease levels of drugs metabolized by this enzyme. However, this effect is unlikely.
Some drugs metabolized by CYP3A4 include amitriptyline (Elavil), amiodarone (Cordarone), citalopram (Celexa), felodipine (Plendil), lansoprazole (Prevacid), ondansetron (Zofran), prednisone (Deltasone, Orasone), sertraline (Zoloft), sibutramine (Meridia), and many others.

Likelihood Unlikely Evidence B
Midazolam (Versed)

In vitro, tangeretin, a constituent of tangerine, appears to increase the metabolism of midazolam in human liver microsomes by up to 52%. However, in humans, drinking tangerine juice 200 mL slightly delayed the absorption, but did not affect the metabolism, of midazolam. Theoretically, tangerine juice might increase the metabolism and reduce the effects of midazolam. However, this effect is unlikely.

Likelihood Unlikely Evidence B
The maker

Brand information

Manufacturer and brand details for Calm Wind Teapills, from the product label.

Plum Flower

Name
Mayway Herbs
City
Oakland
State
CA
Web Address
www.plumflowerherbs.com
Pharmacist Counseling Corner

Calm Wind Teapills by Plum Flower: Common Questions

Does Calm Wind Teapills by Plum Flower interact with any medications?
Yes. Based on its ingredients, Calm Wind Teapills has a known interaction with 813 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Calm Wind Teapills contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Calm Wind Teapills if I'm pregnant or breastfeeding?
No. Peony and atractylodes — two of the main ingredients — are not recommended during pregnancy or breastfeeding because there isn't enough safety data. Talk with your doctor or pharmacist about your options.
What are the main side effects I might experience?
The most common side effects are gastrointestinal: bloating, nausea, diarrhea, loss of appetite, and dry mouth. These tend to be mild. If you experience easy bruising, bleeding gums, or any unusual bleeding while taking this product alongside blood thinners, stop and contact your doctor right away.
Does this product actually work for what it's supposed to treat?
Our data don't show reliable evidence that the ingredients in this blend are effective for any specific condition. The traditional uses are documented, but human studies are lacking. Ask your pharmacist about what you're hoping it will do.
I'm on warfarin. Can I take this?
Do not take this product without checking with your pharmacist or doctor first. Peony may theoretically increase bleeding risk with warfarin, and we need to verify your specific situation. Use the interaction checker on this page with warfarin, then talk to your provider.
What is tangerine peel extract used for in this blend?
Tangerine peel extract has been traditionally used in Chinese medicine, though we don't have established effectiveness data for a specific condition in our records. The peel is safe to eat as food, but concentrated extracts should be used cautiously.
Is this product safe if I'm not taking any medications?
The ingredients are generally well tolerated on their own, though long-term safety hasn't been thoroughly studied. Gastrointestinal side effects like nausea and diarrhea are possible. If you experience any unusual symptoms, stop and contact your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Calm Wind Teapills label
Sources

Sources & How We Checked

Calm Wind Teapills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tangerine 3 references
  1. Yuan, J. M., Wang, X. L., Xiang, Y. B., Gao, Y. T., Ross, R. K., and Yu, M. C. Preserved foods in relation to risk of nasopharyngeal carcinoma in Shanghai, China. Int J Cancer 2000;85(3):358-363. DOI
  2. Backman, J. T., Maenpaa, J., Belle, D. J., Wrighton, S. A., Kivisto, K. T., and Neuvonen, P. J. Lack of correlation between in vitro and in vivo studies on the effects of tangeretin and tangerine juice on midazolam hydroxylation. Clin Pharmacol Ther 2000; PubMed
  3. Vilaplana, J. and Romaguera, C. Contact dermatitis from the essential oil of tangerine in fragrance. Contact Dermatitis 2002;46(2):108. PubMed

See these in context on the Tangerine monograph →

Peony 15 references
  1. Chen LC, Chou MH, Lin MF, Yang LL. Effects of Paeoniae Radix, a traditional Chinese medicine, on the pharmacokinetics of phenytoin. J Clin Pharm Ther 2001;26:271-8. PubMed
  2. Guo TL, Zhou XW. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. Zhong Xi Yi Jie He Za Zhi 1986;6:714-6, 707.
  3. Xie HJ, Yasar U, Sandberg M, Rane A. Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity. J Clin Pharm Ther 2002;27:229-30. . PubMed
  4. Harada M, Suzuki M, Ozaki Y. Effect of Japanese Angelica root and peony root on uterine contraction in the rabbit in situ. J Pharmacobiodyn 1984;7:304-11. PubMed
  5. Anon. Monograph. Peony (Paeonia spp). Alt Med Rev 2001;6:495-9.
  6. Bruynzeel DP. Contact Dermatitis Due to Paeonia (Peony). Contact Dermatitis 1989; 20:152-3..
  7. Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. Prevention of maternal-fetal blood group incompatibility with traditional Chinese herbal medicine. Chin Med J (Engl.) 1998;111(7):585-587.
  8. Wong, A. L. and Chan, T. Y. Interaction between warfarin and the herbal product quilinggao. Ann Pharmacother 2003;37(6):836-838.
  9. Cai Y, Yuan Q, Xu K, et al. Assessment of the therapeutic effect of total glycosides of peony for juvenile idiopathic arthritis: a systematic review and meta-analysis. Evid Based Complement Alternat Med 2016;2016:8292486.
  10. Koo YK, Kim JM, Koo JY, et al. Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa. Pharmazie 2010;65(8):624-8.
  11. Wang W, Tian DD, Zheng B, et al. Peony-glycyrrhiza decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models. Drug Metab Dispos 2015;43(7):1147-53. PubMed
  12. Zhou Y, Jin L, Kong F, et al. Clinical and immunological consequences of total glucosides of paeony treatment in Sjögren's syndrome: A randomized controlled pilot trial. Int Immunopharmacol. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. PubMed
  13. Zhu Q, Qi X, Wu Y, Wang K. Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus. Int Urol Nephrol. 2016 Nov;48(11):1873-1880. doi: 10.1007/s11255-016-1345-5. PubMed
  14. Xu Y, Li X, Chen T, et al. Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice. Phytother Res. 2019;33(1):117-29. [RETRACTED].
  15. Liu X, Li X, Li X, et al. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. Clin Rheumatol. 2019;38(3):657-64. Erratum i

See these in context on the Peony monograph →

Atractylodes 6 references
  1. Liu Y, Jia Z, Dong L, et al. A randomized pilot study of atractylenolide I on gastric cancer cachexia patients. Evid Based Complement Alternat Med 2008;5:337-44. PubMed
  2. Chen Y, Yang W, Guo L, Wu X, Zhang T, Liu J, Zhang J. Atractylodes lactone compounds inhibit platelet activation. Platelets. 2017 Mar;28(2):194-202. PubMed
  3. Jiang H, Shi J, Li Y. Screening for compounds with aromatase inhibiting activities from Atractylodes macrocephala Koidz. Molecules. 2011 Apr 14;16(4):3146-51. PubMed
  4. Koonrungsesomboon N, Na-Bangchang K, Karbwang J. Therapeutic potential and pharmacological activities of Atractylodes lancea (Thunb.) DC. Asian Pac J Trop Med. 2014 Jun;7(6):421-8. PubMed
  5. Li L, Tang LY, Man GC, Yeung BH, Lau CB, Leung PC, Wang CC. Potential reproductive toxicity of Largehead Atractylodes Rhizome, the most commonly used Chinese medicine for threatened miscarriage. Hum Reprod. 2011 Dec;26(12):3280-8. PubMed
  6. Muhamad N, Plengsuriyakarn T, Na-Bangchang K. Atractylodes lancea for cholangiocarcinoma: Modulatory effects on CYP1A2 and CYP3A1 and pharmacokinetics in rats and biodistribution in mice. PLoS One 2022;17(11):e0277614. PubMed

See these in context on the Atractylodes monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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