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Dietary supplement

Cassava Supplement Ingredients & Drug Interactions

by Forever Blessed

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Cassava Supplement is a dietary supplement by Forever Blessed with 1 active ingredient. Its ingredients are commonly taken for dietary staple/source of carbohydrates, fertility aid (to conceive twins), digestive support.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cassava. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Cassava Supplement by Forever Blessed

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This single-ingredient supplement contains cassava. In some parts of the world, cassava root is eaten as a food, but this product delivers a concentrated form in capsule form, which differs from how it's traditionally consumed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: fertility and conceiving twins.
  • We looked for evidence on: Infertility, Twin conception, Ovulation.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for cassava in treating diabetes or diarrhea-related dehydration is insufficient to rate its effectiveness. We don't hold reliable data showing it works for these uses.

The evidence, ingredient by ingredient Cassava

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Properly cooked cassava as a food is generally eaten, but raw or poorly processed cassava can cause cyanide poisoning. Symptoms include nausea, vomiting, stomach pain, diarrhea, dizziness, weakness, and headache.

In rare cases, cassava has triggered allergic reactions (including hives, swelling, and difficulty breathing) in people who also have a latex allergy. The safety data advises against use in pregnancy and while breastfeeding, since there isn't enough information to know it's safe for the developing baby or nursing infant.

Side effects, ingredient by ingredient Cassava

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cassava.
  • The most serious interaction on file is rated Moderate.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take thyroid hormone medication (such as levothyroxine), check with your pharmacist before using this product—cassava can reduce how well your thyroid medication works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement carries a Moderate interaction with thyroid medications and unresolved safety concerns about cyanide content in concentrated supplements. If you take thyroid hormone, talk to your pharmacist before starting.

If you're pregnant, planning pregnancy, or breastfeeding, the safety data suggests avoiding it—discuss with your doctor or pharmacist for personalized advice.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cassava Supplement, straight from the product label.

Brand Forever Blessed
Barcode (UPC) 783583468879
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 229359
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Female (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cassava Supplement by Forever Blessed, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
783583468879
IngredientAmount% DV
Cassava500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions for use: Take one (1) capsule in the morning daily.

Formula

Cassava is a drug-free supplement that naturally increases hyper-ovulation.

Casava Supplement 500mg per capsule

Formulation

Regular use of Cassava Supplement increases chances of twins each month it is taken, with peak chances occurring after 6 months of supplement use.

FDA Statement of Identity

Cassava Fertility Supplement

General Statements

30 Day supply

See for yourself

Cassava Supplement by Forever Blessed label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Cassava Supplement by Forever Blessed

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Cassava

Interacts with
16 drugs
500 mg per serving

Cassava is a starchy root vegetable that feeds millions of people worldwide, but it must be properly cooked or processed because the raw plant contain...

Cassava monograph & interactions
Interaction report

Cassava Supplement by Forever Blessed Drug Interactions

Want to check YOUR meds against Cassava Supplement?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

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16Drugs
16 Moderate

Ingredients driving the most interactions

Cassava 16

Each ingredient & the kinds of drugs it affects

For each ingredient in Cassava Supplement with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cassava1 drug type · 16 drugs

Thyroid Hormone

Evidence from human and animal research suggests that cassava root has marked antithyroid effects, particularly if poorly processed or if consumed as part of a protein-deficient diet. Also, clinical research shows that consuming boiled cassava leaves 200 grams twice daily for 9 days significantly reduces levels of the thyroid hormones triiodothyronine and thyroxine. Theoretically, cassava may alter thyroid function, reduce thyroid hormone levels, and interfere with thyroid hormone-replacement therapy.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Cassava Supplement, from the product label.

Forever Blessed

See all Forever Blessed products
Name
Forever Blessed Twins LLC
City
Fort Myers
State
Florida
ZipCode
33994
Web Address
www.cassavatwins.com
Pharmacist Counseling Corner

Cassava Supplement by Forever Blessed: Common Questions

Does Cassava Supplement by Forever Blessed interact with any medications?
Yes. Based on its ingredients, Cassava Supplement has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cassava Supplement contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Cassava Supplement if I'm on thyroid medication?
No—talk to your pharmacist first. Research shows cassava can lower thyroid hormone levels, so it may interfere with how your medication works. Your dose might need adjustment, or your pharmacist may recommend avoiding this supplement.
Is this safe to take during pregnancy or while breastfeeding?
The safety data advises against it. There isn't enough information to know it's safe for a developing baby or a nursing infant. Talk with your doctor or pharmacist about whether this is right for you.
What are the side effects of cassava?
If cassava isn't properly processed, it can cause nausea, vomiting, stomach pain, diarrhea, dizziness, weakness, and headache from cyanide exposure. Rarely, allergic reactions (hives, swelling, breathing trouble) have been reported, mostly in people with latex allergy.
Does this supplement actually work for diabetes or diarrhea?
The evidence isn't established enough for us to say. There's insufficient reliable data showing cassava works for either condition.
Why does the label say to be careful with how cassava is processed?
Raw or poorly processed cassava contains compounds that break down into cyanide. Good manufacturing removes them, but concentrated supplements haven't been well studied, so the safety data suggests avoiding them.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cassava Supplement is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cassava Supplement label
Go deeper

The Full Monographs Behind Cassava Supplement’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Cassava Supplement's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 30 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cassava 30 references
  1. Hernandez T, Lundquist P, Oliveira L, et al. Fate in humans of dietary intake of cyanogenic glycosides from roots of sweet cassava consumed in Cuba. Nat Toxins 1995;3(2):114-7. PubMed
  2. Ariffin WA, Choo KE, Karnaneedi S. Cassava (ubi kayu) poisoning in children. Med J Malaysia 1992;47(3):231-4.
  3. Tylleskar T, Banea M, Bikangi N, et al. Cassava cyanogens and konzo, an upper motoneuron disease found in Africa. Lancet 1992;339(8787):208-11. PubMed
  4. Akindahunsi AA, Grissom FE, Adewusi SR, et al. Parameters of thyroid function in the endemic goitre of Akungba and Oke-Agbe villages of Akoko area of southwestern Nigeria. Afr J Med Med Sci 1998;27(3-4):239-42.
  5. Osman BA, Ng ML, Bakar AA, Khalid BA. The effect of cassava leave intake on thyroid hormone and urinary iodine. East Afr Med J 1993;70(5):314-5.
  6. Gaitan E, Cooksey RC, Legan J, et al. Antithyroid effects in vivo and in vitro of babassu and mandioca: a staple food in goiter areas of Brazil. Eur J Endocrinol 1994;131(2):138-44. PubMed
  7. Geelhoed GW. Metabolic maladaptation: individual and social consequences of medical intervention in correcting endemic hypothyroidism. Nutrition 1999;15(11-12):908-32. DOI
  8. Biassoni P, Ravera G, Bertocchi J, et al. Influence of dietary habits on thyroid status of a nomadic people, the Bororo shepherds, roaming a central African region affected by severe iodine deficiency. Eur J Endocrinol 1998;138(6):681-5. PubMed
  9. Delange F. The disorders induced by iodine deficiency. Thyroid 1994;4(1):107-28. PubMed
  10. Delange F. [The role of goitrogenic factors distinct from iodine deficiency in the etiology of goiter]. Ann Endocrinol (Paris) 1988;49(4-5):302-5.
  11. Assan R, Assan D, Thiebaut MF, et al. [Diabetogenic tropical pancreatitis]. Diabete Metab 1988;14(3):299-312.
  12. Balakrishnan V, Unnikrishnan AG, Thomas V, et al. Chronic pancreatitis. A prospective nationwide study of 1,086 subjects from India. JOP 2008;9(5):593-600.
  13. Cliff J, Lundqvist P, Martensson J, et al. Association of high cyanide and low sulphur intake in cassava-induced spastic paraparesis. Lancet 1985;2(8466):1211-3. PubMed
  14. Paula Cardoso A, Ernesto M, Nicala D, et al. Combination of cassava flour cyanide and urinary thiocyanate measurements of school children in Mozambique. Int J Food Sci Nutr 2004;55(3):183-90. PubMed
  15. Dumas M, Giordano C, Ndiaye IP, et al. [The concept of tropical neuromyelopathy]. Bull Soc Pathol Exot Filiales 1988;81(2):183-8.
  16. Tucker K, Hedges TR. Food shortages and an epidemic of optic and peripheral neuropathy in Cuba. Nutr Rev 1993;51(12):349-57. PubMed
  17. Wilson J. Cyanide in human disease: a review of clinical and laboratory evidence. Fundam Appl Toxicol 1983;3(5):397-9. DOI
  18. Grange AO. Evaluation of cassava-salt suspension in the management of acute diarrhoea in infants and children. J Diarrhoeal Dis Res 1994;12(1):55-8.
  19. Olusanya O, Olanrewaju DM, Oluwole FA. Studies on the effectiveness, safety and acceptability of fluids from local foodstuffs in the prevention and management of dehydration caused by diarrhoea in children. J Trop Pediatr 1994;40(6):360-4. PubMed
  20. Singh JD. The teratogenic effects of dietary Cassava on the pregnant albino rat: a preliminary report. Teratology 1981;24(3):289-91. PubMed
  21. Oforofuo IA, Omu AE. Serum thiocyanate levels in a normal population and in pregnancy in Benin City, Nigeria: preliminary report. Int J Gynaecol Obstet 1991;34(1):65-9. PubMed
  22. Nikolajsen T, Nielsen F, Rasch V, et al. Uterine contraction induced by Tanzanian plants used to induce abortion. J Ethnopharmacol 2011;137(1):921-5. PubMed
  23. Cardoso AP, Mirione E, Ernesto M, et al. Processing of cassava roots to remove cyanogens. Journal of Food Composition and Analysis 2005;18(5):451-60. DOI
  24. Dorea JG. Maternal thiocyanate and thyroid status during breast-feeding. J Am Coll Nutr 2004;23(2):97-101. PubMed
  25. Sánchez D, Sus S, Ortiz B, Sánchez J, Cardona R. Cross-reactivity Between Cassava and Latex in a Colombian Patient With an Anaphylactic Reaction. J Investig Allergol Clin Immunol. 2015;25(6):453-5.
  26. Rosa ML, Falcão PM, Yokoo EM, et al. Brazil's staple food and incident diabetes. Nutrition. 2014 Mar;30(3):365-8. Epub 2013 Oct 2. PubMed
  27. Banea JP, Bradbury JH, Mandombi C, et al. Control of konzo by detoxification of cassava flour in three villages in the Democratic Republic of Congo. Food Chem Toxicol. 2013 Oct;60:506-13. Epub 2013 Aug 11. PubMed
  28. Boivin MJ, Okitundu D, Makila-Mabe Bumoko G, et al. Neuropsychological effects of konzo: a neuromotor disease associated with poorly processed cassava. Pediatrics. 2013 Apr;131(4):e1231-9. Epub 2013 Mar 25. PubMed
  29. Antolin-Amerigo D, Rodriguez-Rodriguez M, Barbarroja-Escudero J, Postigo Resa I, Uribe-Etxebarría MC, Alvarez-Mon M. Hypersensitivity to cassava: an allergen-based assessment. J Investig Allergol Clin Immunol. 2012;22(5):385-6.
  30. Santos KS, Galvao CE, Gadermaier G, et al. Allergic reactions to manioc (Manihot esculenta Crantz): identification of novel allergens with potential involvement in latex-fruit syndrome. J Allergy Clin Immunol. 2011 Dec;128(6):1367-9. Epub 2011 Aug 19. PubMed

See these in context on the Cassava monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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