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Dietary supplement

Chaga Powder Ingredients & Drug Interactions

by Real Mushrooms

Chaga Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Chaga Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Chaga Powder is a dietary supplement by Real Mushrooms with 1 active ingredient. Its ingredients are commonly taken for immune support, antioxidant support, general wellness/tonic.Based on those ingredients, 494 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chaga Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Chaga Powder by Real Mushrooms

Ask about any prescription or over-the-counter medication and we check it for interactions with Chaga Powder by Real Mushrooms — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Chaga Powder by Real Mushrooms

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Chaga Extract” is listed as a grouped ingredient — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

This product is pure beta-1,3-1,6-glucan, a type of carbohydrate naturally found in chaga mushroom. It's the one active ingredient and makes up the whole powder — there are no inactive fillers or binders listed.

Beta-glucans are compounds your immune system recognizes and responds to, which is why they show up in research on heart health and cholesterol.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Beta-glucans's overall clinical evidence instead.

Strong

Strong clinical evidence supports Beta-glucans for:

Why this rating?
  • The label markets general wellness (“digestive health”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Coronary heart disease (CHD) — rated "Likely Effective" (Natural Medicines).
  • On file: Dyslipidemia — rated "Likely Effective" (Natural Medicines).

The evidence we have shows beta-glucans are likely effective for high cholesterol (dyslipidemia) and coronary heart disease. That said, this product is marketed as chaga powder, and we don't have separate effectiveness data specific to the whole chaga mushroom — only for the beta-glucan it contains.

The evidence, ingredient by ingredient Chaga Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food sources are generally well tolerated. Concentrated supplements like this one, though, haven't been studied as thoroughly at higher doses, so use caution.

In rare cases, very high oral doses have caused temporary liver enzyme changes in a small number of trial participants. There isn't enough research on supplement doses during breastfeeding to be sure either way, so talk it over with your doctor or pharmacist if you're nursing.

Side effects, ingredient by ingredient Chaga Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist if you take blood pressure medications (antihypertensives) or immunosuppressants — both carry Moderate-severity interactions with the beta-glucan in this product. The powder may lower your blood pressure further or interfere with how your immune-suppressing drugs work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Chaga Powder may help with cholesterol and heart health, but it can lower blood pressure and interfere with immune-suppressing drugs. If you take blood pressure medication or immunosuppressants, clear this with your doctor or pharmacist before starting.

For otherwise healthy people with no relevant medications, it's generally well tolerated at normal doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chaga Powder, straight from the product label.

Brand Real Mushrooms
Barcode (UPC) 627843438762
Net contents 60 Gram(s); 2.12 Ounce(s)
Market status On market
Date entered into DSLD Apr 23, 2024
DSLD ID 312718
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chaga Powder by Real Mushrooms, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gram(s)
Maximum serving Sizes:
1 Gram(s)
Servings per container
60
UPC/BARCODE
627843438762
IngredientAmount% DV
Beta-1,3-1,6-Glucan80 mg--
Chaga Extract1000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

100% pure + organic Organic mushroom extract powder

Digestive health

Quality grown Scientifically verified for active compounds

No grain No starch No fillers Non-GMO Gluten-free

Vegan

USDA Organic

Bulk powder

Certified organic and sustainably produced

Our guarantee: This product is verified for active compounds. There are no added starch, grains or mycelium.

Gluten free Non GMO

Vegan

Certified Organic by Quality Assurance international

Formula

Organic mushroom extract powder

Extracts are made from 100% pure Chaga Guaranteed potency: greater than 8% Beta-glucans

Seals/Symbols

USDA Organic

Quality Assurance international Certified Organic

FDA Statement of Identity

Dietary Supplement

General Statements

Purity Potency History Get deals become a VIP customer realmushrooms.com/VIP Our quality commitment to you

Chaga

NPN# 80090960

Suggested/Recommended/Usage/Directions

Suggested use: Adults take 1 gram per day.

Great with tea, coffee & smoothies

Storage

Storage: Store in a cool dry place with zip lock securely closed.

Precautions

Warning: Keep out of reach of children.

Consult a physician if you are pregnant or nursing; have or had a medical condition; or are taking prescription drugs.

Warning: Consuming this product can expose you to chemicals, including lead, which is known to the State of California to cause birth defects or reproductive harm. For more information, go to www.P65Warnings.ca.gov Learn more at realmushrooms.com/prop-65

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Chaga Powder by Real Mushrooms label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Chaga Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Chaga Powder by Real Mushrooms

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Gram(s) Dosage formPowder Servings per container60 Amounts shown are per serving.

Chaga Extract

Interacts with
327 drugs
1000 mg per serving Form: Inonotus obliquus Extract

Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for i...

Chaga Extract monograph & interactions
Interaction report

Chaga Powder by Real Mushrooms Drug Interactions

Want to check YOUR meds against Chaga Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
494Drugs
494 Moderate

Ingredients driving the most interactions

Chaga Extract 327

Individual Drug Interactions

The ingredients in Chaga Powder interact with 494 drugs. Click any drug to see the details.

1 of the 1 ingredient in Chaga Powder interact with drugs. Each result below shows which ingredient is responsible. Chaga Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Chaga Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Chaga Extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that chaga extract can inhibit platelet aggregation. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that chaga might decrease blood glucose levels and increase insulin levels. This has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, chaga might interfere with immunosuppressive therapy.
In vitro research suggests that certain constituents of chaga stimulate immune function. This has not been reported in humans.

Likelihood Possible Evidence D
Chaga Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Chaga Powder, from the product label.

Real Mushrooms

See all Real Mushrooms products
Name
Real Mushrooms Inc.
Street Address
Box 77
City
Roberts Creek
State
BC
ZipCode
V0N2W0
Phone Number
1-800-263-4387
Web Address
realmushrooms.com
Pharmacist Counseling Corner

Chaga Powder by Real Mushrooms: Common Questions

Does Chaga Powder by Real Mushrooms interact with any medications?
Yes. Based on its ingredients, Chaga Powder has a known interaction with 494 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chaga Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does chaga powder actually work?
The beta-glucan in it is likely effective for high cholesterol and coronary heart disease, based on clinical research. Keep in mind that data is strongest for the isolated beta-glucan itself, not necessarily the whole chaga powder product.
Are there any side effects?
Beta-glucans are generally well tolerated. When taken by mouth, serious side effects are rare. Very high doses in a trial caused temporary liver enzyme changes in one patient, but that's not common. Topical beta-glucan products can occasionally cause mild skin reactions.
Can I take this while breastfeeding?
There isn't enough research on concentrated supplement doses during breastfeeding to know either way. Talk with your doctor or pharmacist about whether it's right for you while nursing.
What exactly is beta-glucan?
It's a type of carbohydrate naturally found in mushrooms and some other foods. Your immune system recognizes it and responds to it, which is why it shows up in research on immunity and heart health.
Is this just chaga with fillers?
No — this product lists no inactive ingredients. It's pure chaga extract standardized to beta-1,3-1,6-glucan.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chaga Powder label
Go deeper

The Full Monographs Behind Chaga Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chaga

Interacts with 327 drugs

Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for its benefits is very limited, and it may...

Read the full Chaga monograph → Herb & supplement monograph

Beta-glucans

Interacts with 293 drugs

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...

Read the full Beta-glucans monograph →
Sources

Sources & How We Checked

Chaga Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Chaga 9 references
  1. Sun JE, Ao ZH, Lu ZM, et al. Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. J Ethnopharmacol 2008;118(1):7-13. PubMed
  2. Hyun KW, Jeong SC, Lee DH, et al. Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus. Peptides 2006;27(6):1173-8. PubMed
  3. Kim YO, Han SB, Lee HW, et al. Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus. Life Sci 2005;77(19):2438-56. PubMed
  4. Kikuchi Y, Seta K, Ogawa Y, et al. Chaga mushroom-induced oxalate nephropathy. Clin Nephrol 2014;81(6):440-4. PubMed
  5. Lee S, Lee HY, Park Y, et al. Development of end stage renal disease after long-term ingestion of chaga mushroom: case report and review of literature. J Korean Med Sci. 2020;35(19):e122.
  6. Kwon O, Kim Y, Paek JH, et al. Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report. Medicine (Baltimore) 2022;101(10):e28997. PubMed
  7. Su L, Xin C, Yang J, et al. A polysaccharide from Inonotus obliquus ameliorates intestinal barrier dysfunction in mice with type 2 diabetes mellitus. Int J Biol Macromol 2022;214:312-323. PubMed
  8. Chen S, Ma Y, Li H, et al. Anti-diabetic e?ects of Inonotus obliquus extract in high fat diet combined streptozotocin-induced type 2 diabetic mice. Nutr Hosp 2022;39(6):1256-1263. PubMed
  9. Ye X, Wu K, Xu L, et al. Methanol extract of Inonotus obliquus improves type 2 diabetes mellitus through modifying intestinal flora. Front Endocrinol (Lausanne) 2023;13:1103972. PubMed

See these in context on the Chaga monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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