Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Cheer Up & Chill Out Strawberry Gummies Ingredients & Drug Interactions

by Shaklee Multi-Taskers

Gummy Or Jelly Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Cheer Up & Chill Out Strawberry Gummies is a dietary supplement by Shaklee Multi-Taskers with 5 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 1,377 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ashwagandha Root Extract, L-Theanine, Saffron Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Cheer Up & Chill Out Strawberry Gummies by Shaklee Multi-Taskers

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This gummy contains five active ingredients: vitamin B6, vitamin B12, L-theanine, ashwagandha root extract, and saffron extract. Vitamin B6 and B12 are essential nutrients your body uses for nerve function and energy; L-theanine is an amino acid from tea that supports calm focus; ashwagandha is an herbal extract traditionally used for stress and sleep; and saffron is a spice with potential benefits for mood and cognition.

The remaining ingredients are inactive—tapioca syrup, sugar, water, pectin, natural flavors, acids, monk fruit extract, and lactic acid—which form and sweeten the gummy.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Stress reducer and mood booster.
  • We looked for evidence on: Anxiety, Depression, Fatigue, Athletic performance, Cognitive function, Emotional well-being — and 2 related terms.
  • The strongest evidence on file: Ashwagandha is rated "Possibly Effective" for Anxiety (Natural Medicines).
  • Also on file: Ashwagandha is rated "Possibly Effective" for Generalized anxiety disorder (GAD).
  • Also on file: Theanine is rated "Possibly Effective" for Cognitive function.

The evidence varies by ingredient. Vitamin B6 is effective for sideroblastic anemia and vitamin B6 deficiency, and likely effective for lowering homocysteine; it's possibly effective for pregnancy-related nausea and vomiting.

Vitamin B12 is effective for vitamin B12 deficiency and likely effective for cyanide poisoning; it's possibly effective for canker sores and nerve pain after shingles. L-theanine is possibly effective for cognitive function, but evidence for age-related cognitive decline, Alzheimer's disease, and anxiety disorders is insufficient.

Ashwagandha is possibly effective for insomnia, anxiety, stress, and generalized anxiety disorder, but evidence for bipolar disorder is insufficient. Saffron is possibly effective for chemotherapy-related nerve pain and Alzheimer's disease.

This product is not formulated as a treatment for any one condition, and the amounts of each ingredient in a gummy serving aren't specified here, so efficacy in this form isn't established in our data.

The evidence, ingredient by ingredient Vitamin B6 Vitamin B12 Theanine Ashwagandha Saffron

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B6 is generally well tolerated at standard doses, but high doses over time can damage nerves (sensory neuropathy). Vitamin B12 is very safe with no established upper limit.

L-theanine is generally well tolerated short-term in healthy adults, but long-term safety hasn't been well studied; adverse effects include headaches, drowsiness, and rarely, facial tics. Ashwagandha is generally well tolerated short-term, but serious case reports link it to acute hepatitis and liver failure; drowsiness has been reported.

Saffron is likely safe in food amounts but should be used carefully at supplement doses; it can cause drowsiness, nausea, vomiting, and rarely anaphylaxis. For pregnancy: L-theanine and saffron safety data are insufficient—there isn't enough information to know either way, so talk with your doctor.

Ashwagandha has traditionally been thought to risk miscarriage and should be avoided during pregnancy. Saffron may stimulate the uterus at medicinal doses.

Breastfeeding: B6 and B12 safety data exist and are considered fine at normal amounts; L-theanine and ashwagandha lack sufficient safety data for breastfeeding—discuss with your provider.

Side effects, ingredient by ingredient Vitamin B6 Vitamin B12 Theanine Ashwagandha Saffron

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Saffron, Vitamin B12, Vitamin B6, Ashwagandha, Theanine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications; Parkinson's medications.
  • For scale: 1,378 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications with the tool below if you take any of these: blood pressure medications (antihypertensive drugs), diabetes medications (antidiabetes drugs), sedatives or sleep aids (CNS depressants), anti-anxiety benzodiazepines like Valium or Klonopin, seizure drugs like phenobarbital or Dilantin, heart medications like amiodarone, Parkinson's drugs like levodopa, antidepressants (especially serotonergic drugs), immunosuppressants, thyroid hormones, metformin, or regular caffeine use. These represent the Moderate and Minor severity interactions documented for this product's ingredients.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product brings together several ingredients with documented interactions with common medications—blood pressure drugs, diabetes medications, sedatives, seizure drugs, and others. If you take any prescription medications, check them against this product before starting.

It's especially important if you're on a blood pressure or diabetes medication, sedatives, or seizure drugs. Talk to your pharmacist about whether this product fits your personal health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cheer Up & Chill Out Strawberry Gummies, straight from the product label.

Brand Shaklee Multi-Taskers
Net contents 4.23 Ounce(s); 120 Gram(s); 30 Gummy(ies)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 334702
Product type Other Combinations
Supplement form Gummy Or Jelly
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cheer Up & Chill Out Strawberry Gummies by Shaklee Multi-Taskers, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gummy(ies)
Maximum serving Sizes:
1 Gummy(ies)
Servings per container
30
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates3 Gram(s)1%
Vitamin B617 mg1000%
Vitamin B1224 mcg1000%
Added Sugars2 Gram(s)4%
Total Sugars2 Gram(s)--
L-Theanine100 mg--
Ashwagandha Root Extract50 mg--
Saffron Extract30 mg--

Other ingredients: Tapioca Syrup, Sugar, Water, Pectin, Natural Flavors, Lactic Acid, Malic Acid, Citric Acid, Monk Fruit Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Stress reducer & mood booster

Stress less. Smile more. Shake off stress and find your happy place. Because when stress is low and spirits are high, you can handle anything.

V Vegan

GF Gluten free No artificial flavors, sweeteners, colors, or preservatives

Shaklee since 1956 Safe Proven 100% Guaranteed

Formula

Ashwagandha L-Theanine Saffron B-vitamins

These gummies are formulated with ashwagandha and clinically tested L-theanine to lower stress levels so you can embrace your zen plus B vitamins and clinically tested saffron to help lift your mood.

FDA Statement of Identity

Dietary Supplement

General Statements

Net Wt. 4.23 oz (120 g) / 0.14 oz (4 g) each

Inhale joy, exhale stress.

Precautions

Caution: Not recommended for children, or pregnant or breastfeeding women.

Caution: Not recommended for children, or pregnant or breastfeeding women.

Brand IP Statement(s)

Shaklee since 1956 Safe Proven 100% Guaranteed

Seals/Symbols

Shaklee since 1956 Safe Proven 100% Guaranteed V Vegan 100% Carbon Neutral

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions: Take one gummy.

See for yourself

Cheer Up & Chill Out Strawberry Gummies by Shaklee Multi-Taskers label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Cheer Up & Chill Out Strawberry Gummies by Shaklee Multi-Taskers

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Gummy(ies) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B6

Interacts with
210 drugs
17 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Vitamin B12

Interacts with
20 drugs
24 mcg per serving Form: Cyanocobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

L-Theanine

Interacts with
565 drugs
100 mg per serving

Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without strong dro...

L-Theanine monograph & interactions

Ashwagandha Root Extract

Interacts with
1,372 drugs
50 mg per serving

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evid...

Ashwagandha Root Extract monograph & interactions

Saffron Extract

Interacts with
521 drugs
30 mg per serving

Saffron is a costly spice that has shown promise in early studies for mild-to-moderate depression and some mood and PMS symptoms, but most research us...

Saffron Extract monograph & interactions

Other (inactive) ingredients: Tapioca Syrup, Sugar, Water, Pectin, Natural Flavors, Lactic Acid, Malic Acid, Citric Acid, Monk Fruit Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cheer Up & Chill Out Strawberry Gummies by Shaklee Multi-Taskers Drug Interactions

Want to check YOUR meds against Cheer Up & Chill Out Strawberry Gummies?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,377Drugs
928 Moderate 449 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Cheer Up & Chill Out Strawberry Gummies with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Ashwagandha Root Extract10 drug types · 1,372 drugs

Antidiabetes Drugs

Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.

Likelihood Possible Evidence D
Thyroid Hormone

Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Serotonergic Drugs

Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]

Likelihood Possible Evidence C

L-Theanine3 drug types · 565 drugs

Antihypertensive Drugs

Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Animal research shows that theanine can lower blood pressure in spontaneously hypertensive animals. Theoretically, concomitant use of theanine and antihypertensive drugs might potentiate the antihypertensive activity.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Theoretically, theanine may compete with glutamate and/or increase plasma gamma-aminobutyric acid (GABA) levels, which could cause CNS depression. In one clinical study, some subjects taking oral theanine reported drowsiness.

Likelihood Unlikely Evidence D
Serotonergic Drugs

Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting. Some studies suggest it can increase serotonin levels in the brain while others report that it may decrease them. Nevertheless, there have been no reports of l-theanine being a causative agent in serotonergic-related side effects or serotonin syndrome.

Likelihood Unlikely Evidence C

Saffron Extract4 drug types · 521 drugs

Antidiabetes Drugs

Theoretically, concomitant use of saffron with antidiabetes drugs might increase the risk of hypoglycemia.
Some clinical research shows that taking saffron extract reduces fasting levels of glucose when used in addition to hypoglycemic agents. However, saffron powder itself has not been shown to reduce fasting glucose levels.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, concomitant use of saffron with antihypertensive drugs might have additive effects.
Animal and human research suggests that saffron extract can decrease blood pressure.

Likelihood Possible Evidence D
Caffeine

Theoretically, saffron might inhibit the metabolism of caffeine.
A small clinical study suggests that taking saffron powder 300 mg in 150 mL water daily for 5 days and then taking caffeine 200 mg seems to reduce caffeine metabolite levels in the saliva and urine in males, but not females. Theoretically, this may be due to the inhibition of cytochrome P450 1A2 by saffron.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Clinical research shows that taking saffron extract 60 mg orally daily for 26 weeks can cause drowsiness and sedation. Animal research suggests that adding saffron to hexobarbital further increases sleeping and slows motor activity.

Likelihood Possible Evidence D

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A
The maker

Brand information

Manufacturer and brand details for Cheer Up & Chill Out Strawberry Gummies, from the product label.

Shaklee Multi-Taskers

See all Shaklee Multi-Taskers products
Name
Shaklee Corporation
City
Pleasanton
State
CA
ZipCode
94566
Phone Number
1.800.742.5533
Pharmacist Counseling Corner

Cheer Up & Chill Out Strawberry Gummies by Shaklee Multi-Taskers: Common Questions

Does Cheer Up & Chill Out Strawberry Gummies by Shaklee Multi-Taskers interact with any medications?
Yes. Based on its ingredients, Cheer Up & Chill Out Strawberry Gummies has a known interaction with 1,377 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cheer Up & Chill Out Strawberry Gummies contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on blood pressure medication?
Not without checking first. Four of the five ingredients in this product—vitamin B6, L-theanine, ashwagandha, and saffron—can theoretically lower blood pressure and might cause your pressure to drop too far if combined with your medication. Talk to your pharmacist before starting.
Is this safe during pregnancy?
It depends on the ingredient. Ashwagandha should be avoided during pregnancy because it's traditionally thought to risk miscarriage, and saffron may stimulate the uterus at medicinal doses. L-theanine doesn't have enough safety data—there isn't enough information to know either way, so discuss this product with your doctor or pharmacist if you're pregnant.
What does L-theanine do?
L-theanine is an amino acid found in tea. Evidence suggests it's possibly effective for cognitive function, but the evidence for anxiety and memory loss isn't strong enough to say for sure. It's thought to support calm focus.
Can ashwagandha in this gummy cause liver damage?
Ashwagandha has been linked in rare case reports to acute hepatitis and liver failure. Although serious cases are uncommon, it's a documented risk, especially with longer-term use. If you have any liver concerns or are taking other medications that affect the liver, check with your pharmacist first.
Will this interact with my diabetes medication?
Yes, possibly. Both ashwagandha and saffron in this product can lower blood sugar, and if combined with diabetes medication, they might increase your risk of low blood sugar (hypoglycemia). Check with your pharmacist before starting.
Is vitamin B12 in this product safe?
Yes. Vitamin B12 is very safe—your body removes excess through urine, so there's no established upper limit. The only documented interaction is a minor one with metformin (diabetes medication), and even then, the concern is low B12 levels over time rather than an acute reaction.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cheer Up & Chill Out Strawberry Gummies label
Go deeper

The Full Monographs Behind Cheer Up & Chill Out Strawberry Gummies’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Cheer Up & Chill Out Strawberry Gummies's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 122 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  17. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
  19. Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
  20. de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
  21. Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
  22. Aybak, M., Sermet, A., Ayyildiz, M. O., and Karakilcik, A. Z. Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneimittelforschung. 1995;45(12):1271-1273.
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Vitamin B12 30 references
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Theanine 6 references
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Ashwagandha 32 references
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Saffron 22 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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