Interactions on record — worth a quick check against your medications. Based on 1 of 4 ingredients. Check your meds →
Dietary supplement

Chewable Junior Dophilus Creamy Vanilla Ingredients & Drug Interactions

by Nature's Plus

Chewable Junior Dophilus Creamy Vanilla label
See full label image
Other (e.g. Tea Bag) Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Chewable Junior Dophilus Creamy Vanilla against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Chewable Junior Dophilus Creamy Vanilla is a dietary supplement by Nature's Plus with 4 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillius acidophilis. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Chewable Junior Dophilus Creamy Vanilla by Nature's Plus

Ask about any prescription or over-the-counter medication and we check it for interactions with Chewable Junior Dophilus Creamy Vanilla by Nature's Plus — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Chewable Junior Dophilus Creamy Vanilla by Nature's Plus

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Chewable Junior Dophilus has three active probiotic ingredients: Lactobacillus acidophilus, Lactobacillus casei, and Bifidobacterium. These are live beneficial bacteria meant to support digestive and immune health.

The product also contains several inactive ingredients including fructose, yogurt, sodium caseinate, riboflavin, magnesium stearate, and vanilla flavor.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Children's probiotic supplement for digestive health.
  • We looked for evidence on: Antibiotic-associated diarrhea, Colic, Constipation, Irritable bowel syndrome (IBS), Lactose intolerance, Rotaviral diarrhea — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Constipation, Lactose intolerance, Rotaviral diarrhea, Travelers' diarrhea, and more.

Lactobacillus acidophilus is possibly effective for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis. It's rated possibly ineffective for atopic disease (allergies and eczema).

For acute respiratory distress syndrome, the evidence isn't established enough to rate. We don't hold effectiveness data for the other two ingredients in this product.

The evidence, ingredient by ingredient Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. Gastrointestinal side effects like stomach discomfort, belly pain, indigestion, gas, bloating, diarrhea, vomiting, and burping can occur when taking it with other probiotics, but these are uncommon.

In rare cases, live probiotic organisms have been linked to serious infections like blood infections and abscesses, mostly in people whose immune systems are already compromised or who have underlying conditions — this risk is low in otherwise healthy people. One trial reported rash and itching with a probiotic combination, though it's unclear whether L. acidophilus was the cause.

Side effects, ingredient by ingredient Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lactobacillus Acidophilus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your antibiotic drugs with the search tool on this page before you start this product — timing matters. We couldn't check two of the three ingredients here, so run your exact medications through the checker to be thorough.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with IBS, antibiotic-associated diarrhea, and some other digestive issues if you're interested in trying probiotics. If you take antibiotics, space them out from this supplement so the meds don't kill the beneficial bacteria.

Talk with your pharmacist or doctor before starting, especially if you have a weakened immune system.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chewable Junior Dophilus Creamy Vanilla, straight from the product label.

Brand Nature's Plus
Barcode (UPC) 097467044678
Net contents 90 Wafer(s)
Market status Off market
Date entered into DSLD Oct 25, 2012
DSLD ID 14186
Product type Non-nutrient/non-botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chewable Junior Dophilus Creamy Vanilla by Nature's Plus, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Wafer(s)
Maximum serving Sizes:
1 Wafer(s)
UPC/BARCODE
097467044678
IngredientAmount% DV
Total Carbohydrates1 g1%
Sugar1 g--
Lactobacillus casei100000000 Cell(s)--
Bifidobacterium300000000 Cell(s)--
Lactobacillius acidophilis100000000 Cell(s)--

Other ingredients: Fructose, Yogurt, Sodium Caseinate, Riboflavin, Magnesium Stearate, Vanilla flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Free from soy, yeast, wheat, artificial colors and preservatives.

Formula

Sweetened with fructose.

Contains milk.

Suggested/Recommended/Usage/Directions

DIRECTIONS: As a dietary supplement for children 4 to 12 years of age, one wafer daily, or as recommended by a health care professional.

Storage

For maximum protection of activity, do not store at temperatures above 70(0)F (21(0)C).

KEEP TIGHTLY CLOSED.

FDA Disclaimer Statement

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

PRODUCT NO. 4467 LBL. 1128772

FDA Statement of Identity

Children’s Probiotic Supplement

Seals/Symbols

GLUTEN Free

QUALITY NATURAL SUPPLEMENTS(R)

General Statements

These special strains are contained in a delicious blend of yogurt and natural vanilla flavor, which children will look forward to every day.

Nutritional Support for Healthy Digestion and Overall Well-Being.*

Precautions

KEEP OUT OF REACH OF CHILDREN.

Brand IP Statement(s)

(C)NATURAL ORGANICS(R)

The Energy Supplements(R)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Chewable Junior Dophilus Creamy Vanilla by Nature's Plus label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Chewable Junior Dophilus Creamy Vanilla label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Chewable Junior Dophilus Creamy Vanilla by Nature's Plus

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Wafer(s) Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

1 g per serving

Lactobacillus casei

100000000 Cell(s) per serving

Bifidobacterium

300000000 Cell(s) per serving

Lactobacillius acidophilis

Interacts with
182 drugs
100000000 Cell(s) per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Lactobacillius acidophilis monograph & interactions

Other (inactive) ingredients: Fructose, Yogurt, Sodium Caseinate, Riboflavin, Magnesium Stearate, Vanilla flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chewable Junior Dophilus Creamy Vanilla by Nature's Plus Drug Interactions

Want to check YOUR meds against Chewable Junior Dophilus Creamy Vanilla?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillius acidophilis 182

Individual Drug Interactions

The ingredients in Chewable Junior Dophilus Creamy Vanilla interact with 182 drugs. Click any drug to see the details.

1 of the 4 ingredients in Chewable Junior Dophilus Creamy Vanilla interact with drugs. Each result below shows which ingredient is responsible. Lactobacillius acidophilis

Each ingredient & the kinds of drugs it affects

For each ingredient in Chewable Junior Dophilus Creamy Vanilla with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillius acidophilis1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillius acidophilis full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Chewable Junior Dophilus Creamy Vanilla, from the product label.

Nature's Plus

See all Nature's Plus products
Name
Natural Organics Laboratories, Inc. makers of Nature's Plus
Street Address
9500 New Horizons Blvd.
City
Amityville
State
New York
ZipCode
11701
Web Address
www.naturesplus.com
Pharmacist Counseling Corner

Chewable Junior Dophilus Creamy Vanilla by Nature's Plus: Common Questions

Does Chewable Junior Dophilus Creamy Vanilla by Nature's Plus interact with any medications?
Yes. Based on its ingredients, Chewable Junior Dophilus Creamy Vanilla has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chewable Junior Dophilus Creamy Vanilla contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm on antibiotics?
Antibiotics can kill the live organisms in this probiotic, which may make it less effective. Space them out — your pharmacist can tell you the best timing. Don't take them at the same time.
What are probiotics supposed to do?
This product contains live beneficial bacteria. Lactobacillus acidophilus may help with irritable bowel syndrome, antibiotic-associated diarrhea, bacterial vaginosis, and some Helicobacter pylori infections, though the evidence is still being studied.
Is it safe for kids?
Lactobacillus acidophilus is generally well tolerated in healthy children. That said, the product is labeled for juniors, so follow the age and dose on the package. Ask your pediatrician if you have questions about your child.
Can I take it while pregnant?
Lactobacillus acidophilus is rated possibly safe in pregnancy, but data are limited. Talk with your doctor or pharmacist before starting — they know your full health picture and can give you personalized advice.
What side effects might happen?
Gas, bloating, belly pain, and diarrhea can occur, especially when combined with other probiotics, but these are uncommon. In very rare cases, serious infections have been reported, almost always in people with weak immune systems or existing health conditions.
What's actually in this besides the probiotics?
The active ingredients are the three probiotics. The inactive ingredients are fructose, yogurt, sodium caseinate, riboflavin, magnesium stearate, and vanilla flavor — these help give it taste and texture.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chewable Junior Dophilus Creamy Vanilla is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chewable Junior Dophilus Creamy Vanilla label
Go deeper

The Full Monographs Behind Chewable Junior Dophilus Creamy Vanilla’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph →
Sources

Sources & How We Checked

Chewable Junior Dophilus Creamy Vanilla's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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