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Dietary supplement

Chirositol D-Chiro-Inositol 85 mg Ingredients & Drug Interactions

by Swanson

Chirositol D-Chiro-Inositol 85 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Chirositol D-Chiro-Inositol 85 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Chirositol D-Chiro-Inositol 85 mg is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are D-Chiro-Inositol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Chirositol D-Chiro-Inositol 85 mg by Swanson

Ask about any prescription or over-the-counter medication and we check it for interactions with Chirositol D-Chiro-Inositol 85 mg by Swanson — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Chirositol D-Chiro-Inositol 85 mg by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: D-chiro-inositol at 85 mg per capsule. D-chiro-inositol is a form of inositol, a naturally occurring compound that plays a role in cell signaling and metabolism.

The capsule also contains several inactive ingredients (brown rice flour, gelatin, manganese sulfate, and magnesium stearate), which are standard fillers and binders used in supplement manufacturing.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Inositol's overall clinical evidence instead.

Moderate

Some clinical evidence supports Inositol for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Polycystic ovary syndrome (PCOS) — rated "Possibly Effective" (Natural Medicines).
  • On file: Preterm labor — rated "Possibly Effective" (Natural Medicines).
  • On file: Metabolic syndrome — rated "Possibly Effective" (Natural Medicines).

D-chiro-inositol shows possibly effective evidence for polycystic ovary syndrome (PCOS) and metabolic syndrome. For preterm labor, the evidence is also rated possibly effective.

However, the data we hold shows it is possibly ineffective for anxiety, diabetic nerve pain (diabetic neuropathy), and depression, so it's not the right choice for those concerns.

The evidence, ingredient by ingredient Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

D-chiro-inositol is generally well tolerated at typical doses. The most common side effects when taken by mouth are diarrhea, gas, and nausea—usually mild and digestive in nature.

In pregnancy, safety data is limited; it's been studied in some pregnant women but only under medical supervision. If you're pregnant, breastfeeding, or planning either, talk with your doctor or pharmacist before using this product.

There isn't enough reliable information to know how safe it is in all situations, so caution and professional guidance are wise.

Side effects, ingredient by ingredient Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inositol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes drugs—insulin, metformin, or any other medication to control blood sugar—double-check before starting this product. D-chiro-inositol itself lowers blood glucose, so combining it with your medication could increase the risk of low blood sugar.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with PCOS or metabolic syndrome if that's your concern. If you take diabetes medication, you'll want to check your exact drug before starting—this ingredient can lower blood sugar.

Talk with your pharmacist before adding it to your routine, especially if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chirositol D-Chiro-Inositol 85 mg, straight from the product label.

Brand Swanson
Barcode (UPC) 087614029337
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 308511
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chirositol D-Chiro-Inositol 85 mg by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
087614029337
IngredientAmount% DV
D-Chiro-Inositol85 mg--

Other ingredients: Brown Rice Flour, Gelatin, Manganese Sulfate, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Swanson.com or call 1-800-437-4148

100% Money back guaranteed

Formulation

Total wellness for mind, body & home Unsurpassed purity & potency

Blood Sugar Support

Brand IP Statement(s)

Swanson Science-Backed Quality Since 1969

Chirositol is a registered trademark of Cyvex Nutrition, Inc. d/b/a Nutegrity.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one capsule two times per day with water.

Precautions

Warning: For adults only. Keep out of reach of children.

Consult your healthcare provider before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Do not use if seal is broken.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Chirositol D-Chiro-Inositol 85mg per capsule

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Chirositol D-Chiro-Inositol 85 mg by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Chirositol D-Chiro-Inositol 85 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Chirositol D-Chiro-Inositol 85 mg by Swanson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

D-Chiro-Inositol

Interacts with
86 drugs
85 mg per serving Form: Chirositol M Carob extract

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

D-Chiro-Inositol monograph & interactions

Other (inactive) ingredients: Brown Rice Flour, Gelatin, Manganese Sulfate, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chirositol D-Chiro-Inositol 85 mg by Swanson Drug Interactions

Want to check YOUR meds against Chirositol D-Chiro-Inositol 85 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

D-Chiro-Inositol 86

Individual Drug Interactions

The ingredients in Chirositol D-Chiro-Inositol 85 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Chirositol D-Chiro-Inositol 85 mg interact with drugs. Each result below shows which ingredient is responsible. D-Chiro-Inositol

Each ingredient & the kinds of drugs it affects

For each ingredient in Chirositol D-Chiro-Inositol 85 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

D-Chiro-Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
D-Chiro-Inositol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Chirositol D-Chiro-Inositol 85 mg, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Chirositol D-Chiro-Inositol 85 mg by Swanson: Common Questions

Does Chirositol D-Chiro-Inositol 85 mg by Swanson interact with any medications?
Yes. Based on its ingredients, Chirositol D-Chiro-Inositol 85 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chirositol D-Chiro-Inositol 85 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my PCOS?
D-chiro-inositol is rated possibly effective for PCOS, which means there's some evidence it may help, but it's not proven. Talk with your doctor about whether it's right for your specific situation.
What side effects might I get?
The most common ones are digestive—diarrhea, gas, and nausea. They tend to be mild. Inositol is generally well tolerated when taken by mouth at normal doses.
Can I take this if I'm pregnant?
Safety data is limited. Inositol has been studied in some pregnant women, but only under medical supervision. There isn't enough information to know it's fully safe, so talk with your doctor before using it during pregnancy.
Is this the right supplement for anxiety or depression?
No. The evidence shows D-chiro-inositol is possibly ineffective for both anxiety and depression, so it's not the right choice if those are your main concerns.
What's in this besides the active ingredient?
The capsule contains brown rice flour, gelatin, manganese sulfate, and magnesium stearate—these are standard inactive ingredients used as fillers and binders in capsule supplements.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chirositol D-Chiro-Inositol 85 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chirositol D-Chiro-Inositol 85 mg label
Go deeper

The Full Monographs Behind Chirositol D-Chiro-Inositol 85 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

Chirositol D-Chiro-Inositol 85 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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