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Dietary supplement

Chlorophyll Ingredients & Drug Interactions

by Village Vitality

Liquid Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Chlorophyll is a dietary supplement by Village Vitality with 2 active ingredients. Its ingredients are commonly taken for preventing or treating copper deficiency, supporting red blood cell formation, bone and connective tissue health.Based on those ingredients, 368 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chlorophyll, Copper. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Chlorophyll by Village Vitality

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Village Vitality Chlorophyll liquid contains 2 active ingredients: copper and chlorophyll. Copper is an essential mineral your body uses to support normal function; this product is intended to supply it as a nutritional supplement.

Chlorophyll is the pigment that makes plants green; it's included for its purported health benefits. The liquid also contains vegetable glycerin, deionized water, and peppermint essential oil as inactive ingredients.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Copper deficiency — rated "Likely Effective" (Copper) (Natural Medicines).

Copper is rated likely effective for treating copper deficiency — straightforward use if you're deficient. It's rated possibly ineffective for Alzheimer disease.

For acne, chemotherapy-related anemia, and brain tumors, the evidence isn't established enough to rate it. Chlorophyll has insufficient reliable evidence to support its use for genital herpes, wound healing, shingles, nonmelanoma skin cancer, or pancreatitis — so we don't know whether it works for these purposes.

The evidence, ingredient by ingredient Copper Chlorophyll

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Copper is safe in food and standard supplement amounts, but excess copper is toxic, so stay within recommended doses. It's considered likely safe in pregnancy when you stick to recommended amounts, though one rating flags it as possibly unsafe — talk with your doctor about your specific dose.

Copper is likely safe while breastfeeding. Chlorophyll is generally well tolerated in short-term use, but thorough long-term safety data are limited.

The most common side effect is photosensitization (sun sensitivity); topical use can also cause skin irritation. Rarely, oral chlorophyll has caused pseudoporphyria, a condition producing blisters on the hands.

Chlorophyll is not recommended during pregnancy or breastfeeding — the data aren't strong enough to know it's safe.

Side effects, ingredient by ingredient Copper Chlorophyll

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Chlorophyll, Copper.
  • The most serious interaction on file is rated Moderate.
  • For scale: 368 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check with us if you're on methotrexate or photosensitizing drugs (both moderate interactions with chlorophyll), penicillamine (moderate interaction with copper), or birth control pills (minor interaction with copper). No interactions are documented for the ingredients we could check only if there are unchecked ingredients — but these two are linked and checked.

Run your exact medications through the search tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product is aimed at supplementing copper and delivering chlorophyll, but it's not right for everyone. If you take penicillamine, methotrexate, birth control pills, or photosensitizing medications, check with us first.

Pregnant or breastfeeding? Talk to your pharmacist or doctor before starting — the safety data for chlorophyll especially don't support its use in those situations.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chlorophyll, straight from the product label.

Brand Village Vitality
Barcode (UPC) 788332129919
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Mar 24, 2020
DSLD ID 215475
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chlorophyll by Village Vitality, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 mL
Maximum serving Sizes:
0.5 mL
Servings per container
59
UPC/BARCODE
788332129919
IngredientAmount% DV
Copper2 mg100%
Chlorophyll50 mg--

Other ingredients: Vegetable Glycerin, deionized Water, Peppermint essential Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take 15 drops in a cup of water 1-3 times per day.

Shake well before using.

Precautions

Warning: Stains: Keep off clothing.

Keep out of the reach of children.

FDA Statement of Identity

Herbal Supplement

See for yourself

Chlorophyll by Village Vitality label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Chlorophyll by Village Vitality

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.5 mL Dosage formLiquid Servings per container59 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Copper

Interacts with
31 drugs
2 mg per serving

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes wor...

Copper monograph & interactions

Chlorophyll

Interacts with
337 drugs
50 mg per serving Form: Mulberry, Sodium Copper Chlorophyllin

Chlorophyll is the green pigment found in plants and algae, and supplements often use a stable form called chlorophyllin. It is most studied for reduc...

Chlorophyll monograph & interactions

Other (inactive) ingredients: Vegetable Glycerin, Deionized Water, Peppermint essential Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chlorophyll by Village Vitality Drug Interactions

Want to check YOUR meds against Chlorophyll?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
368Drugs
338 Moderate 30 Minor

Ingredients driving the most interactions

Copper 31

Each ingredient & the kinds of drugs it affects

For each ingredient in Chlorophyll with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Chlorophyll2 drug types · 337 drugs

Methotrexate (Trexall, Others)

Theoretically, chlorophyll may reduce the clearance of methotrexate.
In one case report, a 54-year-old male developed delayed clearance of intravenous high-dose methotrexate with concomitant use of chlorophyll. When chlorophyll was stopped 2 days prior to methotrexate treatment, methotrexate clearance was unaffected.

Likelihood Possible Evidence B
Photosensitizing Drugs

Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Chlorophyll has been reported to cause photosensitization. In two case reports, pseudoporphyria developed after oral intake of chlorophyll. Theoretically, concomitant use with other photosensitizing drugs may exacerbate this effect.

Likelihood Probable Evidence B

Copper2 drug types · 31 drugs

Penicillamine (Cuprimine, Depen)

Theoretically, taking copper with penicillamine might decrease the absorption of penicillamine; separate dosing by at least 2 hours.
Copper chelates penicillamine, which decreases its absorption and may reduce its clinical effects.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking copper with contraceptive drugs might increase the levels and toxic effects of copper.
A meta-analysis of clinical studies suggests that chronic use of oral contraceptives increases serum copper levels by a mean of 57 mcg/dL. In most people, this resulted in levels above the normal reference range for copper.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Chlorophyll, from the product label.

Village Vitality

See all Village Vitality products
Name
Village Vitality LLC
Street Address
79 Tinker St. Floor 2
City
Woodstock
State
NY
ZipCode
12498
Pharmacist Counseling Corner

Chlorophyll by Village Vitality: Common Questions

Does Chlorophyll by Village Vitality interact with any medications?
Yes. Based on its ingredients, Chlorophyll has a known interaction with 368 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chlorophyll contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm trying to get pregnant or am pregnant?
The data aren't strong enough. Copper is listed as possibly unsafe in pregnancy, and chlorophyll isn't recommended during pregnancy at all — the safety information just isn't there. Talk with your pharmacist or doctor about whether this product is right for you before you take it.
Can I take this while breastfeeding?
Copper is considered likely safe while breastfeeding in recommended amounts. Chlorophyll is a different story — safety during breastfeeding is unknown, so it's best avoided unless your doctor specifically advises otherwise. Check with your pharmacist.
What does copper actually do in my body?
Copper is an essential mineral — your body uses it to support normal functions. This product is intended to supply it if you're deficient. Taking too much, though, can be toxic, so stick to recommended doses.
Can chlorophyll cause sun sensitivity?
Yes. Photosensitization — increased sensitivity to sunlight — is the most common side effect of oral chlorophyll. In rare cases, people have developed pseudoporphyria, a condition with blisters and easily traumatized skin, after taking chlorophyll drinks.
Is this product 'all natural' or free of fillers?
The two active ingredients are copper and chlorophyll. It also contains vegetable glycerin, deionized water, and peppermint essential oil as inactive ingredients — so yes, there are other ingredients in the bottle beyond the actives.
Does this really work for wound healing or herpes?
There isn't enough reliable evidence to say. Chlorophyll is listed as having insufficient evidence for wound healing, genital herpes, and shingles — so we don't know whether it actually works for those purposes.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chlorophyll is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chlorophyll label
Sources

Sources & How We Checked

Chlorophyll's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Copper 11 references
  1. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  2. Campbell IA, Elmes PC. Ethambutol and the eye: zinc and copper (letter). Lancet 1975;2:711. DOI
  3. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  4. Kozak SF, Inderlied CB, Hsu HY, et al. The role of copper on ethambutol's antimicrobial action and implications for ethambutol-induced optic neuropathy. Diag Microbiol Infect Dis 1998;30:83-7. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cantilena LR, Klaassen CD. The effect of chelating agents on the excretion of endogenous metals. Toxicol Appl Pharmacol 1982;63:344-50.
  7. Babic Z, Tariba B, Kovacic J, Pizent A, Varnai VM, Macan J. Relevance of serum copper elevation induced by oral contraceptives: a meta-analysis. Contraception. 2013 Jun;87(6):790-800. PubMed
  8. Qui Q, Zhang F, Zhu W, Wu J, Liang M. Copper in diabetes mellitus: a meta-analysis and systematic review of plasma and serum studies. Biol Trace Elem Res 2017;177(1):53-63.
  9. Walker-Smith PK, Keith DJ, Kennedy CT, Sansom JE. Allergic contact dermatitis caused by copper. Contact Dermatitis 2016;75(3):186-7. PubMed
  10. Gallentine A. Third-degree burn on the neuropathic lower extremity in a patient with diabetes while wearing a copper-containing compression sock: a case report. Wound Manag Prev 2021;67(12):26-29. DOI
  11. Chung KJ, Chin YM, Wong MS, Sanmugam A, Singaravel S, Nah SA. Effectiveness of table salt versus copper sulphate in treating umbilical granuloma: A pilot randomized controlled trial. J Pediatr Surg 2022;57(2):261-265. PubMed

See these in context on the Copper monograph →

Chlorophyll 5 references
  1. Mathews-Roth MM. Carotenoids in erythropoietic protoporphyria and other photosensitivity diseases. Ann N Y Acad Sci, 1993; 691:127-38. PubMed
  2. Belen'kii, G. B. and Krikun, B. L. [Treatment of herpes simplex and herpes zoster by chlorophyll preparations]. Sov.Med. 1971;34(1):151-152.
  3. Brooks SL, Sanders J, Seymour JF, Mellor JD. A case of delayed methotrexate clearance following administration of a complementary medication containing chlorophyll. J Oncol Pharm Pract. 2014 Jun;20(3):225-8. PubMed
  4. Rossi E, Borchard K, Cole JM. Pseudoporphyria following self-medication with chlorophyll. Australas J Dermatol. 2015 Feb;56(1):47-8. PubMed
  5. Zhao CY, Frew JW, Muhaidat J, et al. Chlorophyll-induced pseudoporphyria with ongoing photosensitivity after cessation - a case series of four patients. J Eur Acad Dermatol Venereol 2016;30(7):1239-42. PubMed

See these in context on the Chlorophyll monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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