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Dietary supplement

Chlorophyll Ingredients & Drug Interactions

by Village Vitality

Chlorophyll label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Chlorophyll against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Chlorophyll is a dietary supplement by Village Vitality with 2 active ingredients. Its ingredients are commonly taken for preventing or treating copper deficiency, supporting red blood cell formation, bone and connective tissue health.Based on those ingredients, 368 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chlorophyll, Copper. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Chlorophyll by Village Vitality

Ask about any prescription or over-the-counter medication and we check it for interactions with Chlorophyll by Village Vitality — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Chlorophyll by Village Vitality

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Village Vitality Chlorophyll Liquid contains 2 active ingredients: copper and chlorophyll. Copper is an essential mineral your body needs in small amounts for nerve and bone health, and it's used to treat copper deficiency.

Chlorophyll is the green pigment plants use to capture sunlight. The product also contains vegetable glycerin, deionized water, and peppermint essential oil as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Body and breath odor reduction.
  • We looked for evidence on: Colostomy odor, Halitosis, General body odor.
  • The closest evidence on file: Chlorophyll is rated "Insufficient Reliable Evidence To Rate" for Colostomy odor (Natural Medicines).
  • Also on file: Chlorophyll is rated "Insufficient Reliable Evidence To Rate" for Halitosis.

Copper is likely effective for treating copper deficiency. For other conditions — including Alzheimer disease, acne, chemotherapy-related anemia, and brain tumors — the evidence is either insufficient or suggests it may not help.

Chlorophyll's effectiveness hasn't been established in our data for genital herpes, wound healing, shingles, nonmelanoma skin cancer, or pancreatitis.

The evidence, ingredient by ingredient Copper Chlorophyll

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Copper is generally well tolerated in the amounts found in food and standard supplements, but excess copper can be toxic. Copper is needed during pregnancy, though you should stay within recommended amounts and avoid high-dose supplements unless your doctor advises it.

Chlorophyll is generally well tolerated in short-term use, but high-quality safety data are limited. The most common side effect with oral chlorophyll is photosensitization (increased sun sensitivity).

Rarely, pseudoporphyria (blistering and fragile skin) has been reported after taking chlorophyll by mouth. Contact dermatitis from copper has been reported rarely.

Side effects, ingredient by ingredient Copper Chlorophyll

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Chlorophyll, Copper.
  • The most serious interaction on file is rated Moderate.
  • For scale: 368 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist if you take methotrexate or other photosensitizing drugs (Moderate severity); penicillamine or certain copper-chelating medications (Moderate); or birth control pills (Minor). Spacing penicillamine 2 hours apart from this product may help reduce the interaction.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is worth considering if you have a copper deficiency. If you take penicillamine, birth control pills, methotrexate, or any photosensitizing medication, check with your pharmacist before starting.

Avoid high doses of copper unless your doctor recommends it. Talk to your pharmacist about whether this product fits your health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chlorophyll, straight from the product label.

Brand Village Vitality
Barcode (UPC) 788332129926
Net contents 2 Fluid Ounce(s); 59 mL
Market status On market
Date entered into DSLD Mar 24, 2020
DSLD ID 215478
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chlorophyll by Village Vitality, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 mL
Maximum serving Sizes:
0.5 mL
Servings per container
118
UPC/BARCODE
788332129926
IngredientAmount% DV
Copper2 mg100%
Chlorophyll50 mg--

Other ingredients: Vegetable Glycerin, deionized Water, Peppermint essential Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take 15 drops in a cup of water 1-3 times per day.

Shake well before using.

Precautions

Warning: Stains: Keep off clothing.

Keep out of the reach of children.

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Chlorophyll by Village Vitality label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Chlorophyll label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Chlorophyll by Village Vitality

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.5 mL Dosage formLiquid Servings per container118 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Copper

Interacts with
31 drugs
2 mg per serving

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes wor...

Copper monograph & interactions

Chlorophyll

Interacts with
337 drugs
50 mg per serving Form: Mulberry, Sodium Copper Chlorophyllin

Chlorophyll is the green pigment found in plants and algae, and supplements often use a stable form called chlorophyllin. It is most studied for reduc...

Chlorophyll monograph & interactions

Other (inactive) ingredients: Vegetable Glycerin, Deionized Water, Peppermint essential Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chlorophyll by Village Vitality Drug Interactions

Want to check YOUR meds against Chlorophyll?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
368Drugs
338 Moderate 30 Minor

Ingredients driving the most interactions

Chlorophyll 337
Copper 31

Individual Drug Interactions

The ingredients in Chlorophyll interact with 368 drugs. Click any drug to see the details.

2 of the 2 ingredients in Chlorophyll interact with drugs. Each result below shows which ingredient is responsible. Chlorophyll Copper

Each ingredient & the kinds of drugs it affects

For each ingredient in Chlorophyll with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Chlorophyll2 drug types · 337 drugs

Methotrexate (Trexall, Others)

Theoretically, chlorophyll may reduce the clearance of methotrexate.
In one case report, a 54-year-old male developed delayed clearance of intravenous high-dose methotrexate with concomitant use of chlorophyll. When chlorophyll was stopped 2 days prior to methotrexate treatment, methotrexate clearance was unaffected.

Likelihood Possible Evidence B
Photosensitizing Drugs

Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Chlorophyll has been reported to cause photosensitization. In two case reports, pseudoporphyria developed after oral intake of chlorophyll. Theoretically, concomitant use with other photosensitizing drugs may exacerbate this effect.

Likelihood Probable Evidence B
Chlorophyll full monograph & interactions

Copper2 drug types · 31 drugs

Penicillamine (Cuprimine, Depen)

Theoretically, taking copper with penicillamine might decrease the absorption of penicillamine; separate dosing by at least 2 hours.
Copper chelates penicillamine, which decreases its absorption and may reduce its clinical effects.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking copper with contraceptive drugs might increase the levels and toxic effects of copper.
A meta-analysis of clinical studies suggests that chronic use of oral contraceptives increases serum copper levels by a mean of 57 mcg/dL. In most people, this resulted in levels above the normal reference range for copper.

Likelihood Possible Evidence D
Copper full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Chlorophyll, from the product label.

Village Vitality

See all Village Vitality products
Name
Village Vitality LLC
Street Address
79 Tinker St. Floor 2
City
Woodstock
State
NY
ZipCode
12498
Pharmacist Counseling Corner

Chlorophyll by Village Vitality: Common Questions

Does Chlorophyll by Village Vitality interact with any medications?
Yes. Based on its ingredients, Chlorophyll has a known interaction with 368 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chlorophyll contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take during pregnancy?
The safety data are mixed. Copper is likely safe and is actually needed during pregnancy, but you should stick to recommended amounts and avoid high-dose supplements unless your doctor advises it. Chlorophyll, on the other hand, doesn't have enough reliable safety information, and the data advise against it during pregnancy. Talk with your doctor or pharmacist about whether this product is right for you.
What about breastfeeding?
Copper in recommended amounts is considered likely safe during breastfeeding. Chlorophyll's safety during breastfeeding is unknown, so it's best avoided unless your doctor advises otherwise. If you're nursing, check with your pharmacist before starting.
Can this help with wound healing?
The evidence for chlorophyll in wound healing hasn't been established in our data, so we can't say whether it works for that purpose.
What are the side effects I should watch for?
The most common side effect is photosensitization — increased sensitivity to sunlight — from the chlorophyll. Dermatitis (skin irritation) can happen too. Rarely, blistering and fragile skin have been reported. Contact dermatitis from copper is rare. If you spend a lot of time in the sun or have sensitive skin, mention this product to your pharmacist.
Is this product just chlorophyll, or does it have other active ingredients?
It contains two active ingredients: chlorophyll and copper. The other ingredients — vegetable glycerin, deionized water, and peppermint essential oil — are just there to make the liquid and add flavor.
Will this help my copper deficiency?
Copper is likely effective for treating copper deficiency, so if that's why you're considering this product, it's a reasonable choice. That said, make sure a doctor has confirmed you actually have a deficiency before you start — excess copper can be toxic.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chlorophyll is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chlorophyll label
Go deeper

The Full Monographs Behind Chlorophyll’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Copper

Interacts with 31 drugs

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes work. Most people get enough copper from fo...

Read the full Copper monograph → Herb & supplement monograph

Chlorophyll

Interacts with 337 drugs

Chlorophyll is the green pigment found in plants and algae, and supplements often use a stable form called chlorophyllin. It is most studied for reducing body and fecal odor and as a topical...

Read the full Chlorophyll monograph →
Sources

Sources & How We Checked

Chlorophyll's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Copper 11 references
  1. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  2. Campbell IA, Elmes PC. Ethambutol and the eye: zinc and copper (letter). Lancet 1975;2:711. DOI
  3. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  4. Kozak SF, Inderlied CB, Hsu HY, et al. The role of copper on ethambutol's antimicrobial action and implications for ethambutol-induced optic neuropathy. Diag Microbiol Infect Dis 1998;30:83-7. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cantilena LR, Klaassen CD. The effect of chelating agents on the excretion of endogenous metals. Toxicol Appl Pharmacol 1982;63:344-50.
  7. Babic Z, Tariba B, Kovacic J, Pizent A, Varnai VM, Macan J. Relevance of serum copper elevation induced by oral contraceptives: a meta-analysis. Contraception. 2013 Jun;87(6):790-800. PubMed
  8. Qui Q, Zhang F, Zhu W, Wu J, Liang M. Copper in diabetes mellitus: a meta-analysis and systematic review of plasma and serum studies. Biol Trace Elem Res 2017;177(1):53-63.
  9. Walker-Smith PK, Keith DJ, Kennedy CT, Sansom JE. Allergic contact dermatitis caused by copper. Contact Dermatitis 2016;75(3):186-7. PubMed
  10. Gallentine A. Third-degree burn on the neuropathic lower extremity in a patient with diabetes while wearing a copper-containing compression sock: a case report. Wound Manag Prev 2021;67(12):26-29. DOI
  11. Chung KJ, Chin YM, Wong MS, Sanmugam A, Singaravel S, Nah SA. Effectiveness of table salt versus copper sulphate in treating umbilical granuloma: A pilot randomized controlled trial. J Pediatr Surg 2022;57(2):261-265. PubMed

See these in context on the Copper monograph →

Chlorophyll 5 references
  1. Mathews-Roth MM. Carotenoids in erythropoietic protoporphyria and other photosensitivity diseases. Ann N Y Acad Sci, 1993; 691:127-38. PubMed
  2. Belen'kii, G. B. and Krikun, B. L. [Treatment of herpes simplex and herpes zoster by chlorophyll preparations]. Sov.Med. 1971;34(1):151-152.
  3. Brooks SL, Sanders J, Seymour JF, Mellor JD. A case of delayed methotrexate clearance following administration of a complementary medication containing chlorophyll. J Oncol Pharm Pract. 2014 Jun;20(3):225-8. PubMed
  4. Rossi E, Borchard K, Cole JM. Pseudoporphyria following self-medication with chlorophyll. Australas J Dermatol. 2015 Feb;56(1):47-8. PubMed
  5. Zhao CY, Frew JW, Muhaidat J, et al. Chlorophyll-induced pseudoporphyria with ongoing photosensitivity after cessation - a case series of four patients. J Eur Acad Dermatol Venereol 2016;30(7):1239-42. PubMed

See these in context on the Chlorophyll monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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