Citrulline Malate Ingredients & Drug Interactions
by NutraBio
What is this page for?
First and foremost: checking Citrulline Malate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Citrulline Malate is a dietary supplement by NutraBio with 1 active ingredient. Its ingredients are commonly taken for exercise performance, muscle soreness and fatigue, blood flow and circulation.Based on those ingredients, 178 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Citrulline DL-Malate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Citrulline Malate by NutraBio
Ask about any prescription or over-the-counter medication and we check it for interactions with Citrulline Malate by NutraBio — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Citrulline Malate by NutraBio
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — L-citrulline.
- The most serious interaction on file is rated Moderate.
- For scale: 178 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Citrulline Malate, straight from the product label.
| Brand | NutraBio |
|---|---|
| Barcode (UPC) | 649908235314 |
| Net contents | 500 Gram(s); 1.1 lbs |
| Market status | On market |
| Date entered into DSLD | Oct 22, 2015 |
| DSLD ID | 51192 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Kosher, No Allergies, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Citrulline Malate by NutraBio, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Citrulline DL-Malate | 3000 mg | -- |
Other ingredients: Absolutely None
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Zero fillers or excipients inferior ingredients banned substances - added sugars proprietary blends hidden ingredients
- Allergen free - Non-GMO - Gluten free - BSE/TSE free
Vegetarian
- No fillers - No excipients - No additives
Kosher, Vegetarian, Hypoallergenic, Non-GMO, Gluten free and BSE/TSE free. No added sugars, salt, preservatives, salicylates, or artificial color, flavor or fragrance.
Kosher, Vegetarian, Hypoallergenic, Non-GMO, Gluten free and BSE/TSE free. No added sugars, salt, preservatives, salicylates, or artificial color, flavor or fragrance.
Suggested/Recommended/Usage/Directions
1 serving - Mixed with 8-16 oz. favorite beverage - 1-2x daily Suggested Use: As a dietary supplement, take 1 level scoop (3g) mixed into your favorite beverage, 1-2 times daily or as directed by your physician. For maximum benefit, take up to (6000mg) per day. For best results, shake for 15 to 20 seconds using a shaker cup or mix thoroughly with a spoon. May be hygroscopic and may clump during storage which will not affect the quality of the product.
Formula
- Allergen free
Kosher, Vegetarian, Hypoallergenic, Non-GMO, Gluten free and BSE/TSE free.
Kosher, Vegetarian, Hypoallergenic, Non-GMO, Gluten free and BSE/TSE free. No added sugars, salt, preservatives, salicylates, or artificial color, flavor or fragrance.
Precautions
Warning: Not Intended for use by persons under the age of 18. Keep out of the reach of children.
If you are pregnant, breast feeding, have known medical conditions (including kidney or liver disease) or are taking prescription or OTC medication(s) consult with your health care practitioner before using this product.
General Statements
Manufactured in a GMP & FDA inspected facility
Nitric Oxide - Recovery
Made in a GMP & FDA inspected facility
Pharmaceutical grade amino acid
Improves muscle performance & recovery. Increases nitric oxide production. Reduces lactic acid & ammonia.
Powder 166 servings
Serving scoop included. (May settle to the bottom during shipping.)
Quality and purity since 1996. NutraBio manufactures in our own FDA registered & inspected GMP facility complying with FDA 21 CFR Part 111 regulations.
Since 1996
Seals/Symbols
TRUE LABEL FULL LABEL DISCLOSURE
OU
FDA Statement of Identity
Dietary Supplement
Storage
Store in a cool dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.
General
23531-006 B20174-001
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Citrulline Malate by NutraBio label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Citrulline Malate by NutraBio
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size3 Gram(s) Dosage formPowder Servings per container166 Amounts shown are per serving.
L-Citrulline DL-Malate
Interacts with178 drugs
L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. I...
L-Citrulline DL-Malate monograph & interactionsOther (inactive) ingredients: Absolutely None. These complete the product’s ingredient list but are not active constituents.
Citrulline Malate by NutraBio Drug Interactions
Citrulline Malate contains a single active ingredient, and it has known interactions with 178 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Citrulline Malate?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Citrulline Malate interact with 178 drugs. Click any drug to see the details.
1 of the 1 ingredient in Citrulline Malate interact with drugs. Each result below shows which ingredient is responsible. L-Citrulline DL-Malate
BumetanideBurinex
How Bumetanide interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Bumetanide interactionBumetanide (iv)Bumex
How Bumetanide (iv) interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Bumetanide (iv) interactionBumetanide (oral)Bumex
How Bumetanide (oral) interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Bumetanide (oral) interactionCandesartan CilexetilAmias, Atacand
How Candesartan Cilexetil interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Candesartan Cilexetil interactionCandesartan Cilexetil, HydrochlorothiazideAtacand HCT
How Candesartan Cilexetil, Hydrochlorothiazide interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Candesartan Cilexetil, Hydrochlorothiazide interactionCaptoprilAcepril, Capoten
How Captopril interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Captopril interactionCaptopril, HydrochlorothiazideAcezide, Capozide
How Captopril, Hydrochlorothiazide interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Captopril, Hydrochlorothiazide interactionCarteololCartrol, Ocupress
How Carteolol interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Carteolol interactionCarvedilolCoreg, Coreg CR
How Carvedilol interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Carvedilol interactionCeliprololCelicard
How Celiprolol interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Celiprolol interactionChlorothiazideDiuril
How Chlorothiazide interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Chlorothiazide interactionChlorothiazide, MethyldopaAldochlor, Aldoclor 150, Aldoclor 250
How Chlorothiazide, Methyldopa interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Chlorothiazide, Methyldopa interactionChlorothiazide, ReserpineDiupres
How Chlorothiazide, Reserpine interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Chlorothiazide, Reserpine interactionChlorthalidoneHygroton, Thalitone
How Chlorthalidone interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Chlorthalidone interactionChlorthalidone, ClonidineClorpres, Combipres
How Chlorthalidone, Clonidine interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Chlorthalidone, Clonidine interactionCilazaprilInhibace
How Cilazapril interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Cilazapril interactionClevidipineCleviprex
How Clevidipine interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Clevidipine interactionClonidineCatapres
How Clonidine interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Clonidine interactionCryptenamine, MethyclothiazideDiutensen
How Cryptenamine, Methyclothiazide interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Cryptenamine, Methyclothiazide interactionCyclothiazideAnhydron, Fluidil
How Cyclothiazide interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Cyclothiazide interactionDeserpidineHarmonyl
How Deserpidine interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Deserpidine interactionDeserpidine, HydrochlorothiazideOreticyl, Oreticyl Forte
How Deserpidine, Hydrochlorothiazide interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Deserpidine, Hydrochlorothiazide interactionDeserpidine, MethyclothiazideEnduronyl, Enduronyl Forte
How Deserpidine, Methyclothiazide interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Deserpidine, Methyclothiazide interactionDiltiazemAdizem-SR, Adizem-XL, Angitil SR, Angitil XL, Calcicard CR, Cardizem +23 more
How Diltiazem interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Diltiazem interactionDiltiazem, EnalaprilTeczem
How Diltiazem, Enalapril interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Diltiazem, Enalapril interactionDoxazosin MesylateCardura
How Doxazosin Mesylate interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Doxazosin Mesylate interactionEnalapril MaleateEpaned, Vasotec
How Enalapril Maleate interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Enalapril Maleate interactionEnalapril Maleate, FelodipineLexxel
How Enalapril Maleate, Felodipine interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Enalapril Maleate, Felodipine interactionEnalapril Maleate, HydrochlorothiazideVaseretic
How Enalapril Maleate, Hydrochlorothiazide interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Enalapril Maleate, Hydrochlorothiazide interactionEplerenoneInspra
How Eplerenone interacts with Citrulline Malate — through 1 ingredient. Tap an ingredient for the detail:
L-citrulline Dl-malateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline Dl-malate + Eplerenone interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Citrulline Malate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
L-Citrulline DL-Malate
Antihypertensive Drugs
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.
Phosphodiesterase-5 Inhibitors
Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.
Brand information
Manufacturer and brand details for Citrulline Malate, from the product label.
NutraBio
See all NutraBio products- Name
- NutraBio Labs, Inc.
- Street Address
- 564 Lincoln Blvd.
- City
- Middlesex
- State
- NJ
- ZipCode
- 08846
- Phone Number
- 732-748-8606
- Web Address
- www.nutrabio.com
Citrulline Malate by NutraBio: Common Questions
Does Citrulline Malate by NutraBio interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Citrulline Malate is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Citrulline Malate’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Citrulline Malate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 8 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
L-citrulline 8 references
- Cheng JW, Balwin SN. L-arginine in the management of cardiovascular diseases. Ann Pharmacother 2001;35:755-64. PubMed
- Schwedhelm E, Maas R, Freese R, et al. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol 2008;65:51-9. PubMed
- Romero MJ, Platt DH, Caldwell RB, Caldwell RW. Therapeutic use of citrulline in cardiovascular disease. Cardiovasc Drug Rev 2006;24:275-90. PubMed
- Balderas-Munoz K, Castillo-Martínez L, Orea-Tejeda A, et al. Improvement of ventricular function in systolic heart failure patients with oral L-citrulline supplementation. Cardiol J 2012;19:612-7. PubMed
- Sharif Kashani B, Tahmaseb Pour P, Malekmohammad M, et al. Oral l-citrulline malate in patients with idiopathic pulmonary arterial hypertension and Eisenmenger Syndrome: a clinical trial. J Cardiol 2014;64:231-5. PubMed
- Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res 2010;24:1215-22. PubMed
- Mirenayat MS, Moradi S, Mohammadi H, Rouhani MH. Effect of L-citrulline supplementation on blood pressure: a systematic review and meta-analysis of clinical trials. Curr Hypertens Rep. 2018;20(11):98. PubMed
- Xu Z, Liu C, Liu S, Zhou Z. Comparison of efficacy and safety of daily oral L-arginine and PDE5Is alone or combination in treating erectile dysfunction: A systematic review and meta-analysis of randomised controlled trials. Andrologia. 2021:e14007. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC