Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Coconut Oil Ingredients & Drug Interactions

by GNC SuperFoods

Coconut Oil label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Coconut Oil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Coconut Oil is a dietary supplement by GNC SuperFoods with 2 active ingredients. Its ingredients are commonly taken for skin and hair care, source of dietary fats (mcts), hydration with coconut water.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are organic Coconut Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Coconut Oil by GNC SuperFoods

Ask about any prescription or over-the-counter medication and we check it for interactions with Coconut Oil by GNC SuperFoods — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Coconut Oil by GNC SuperFoods

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

GNC SuperFoods Coconut Oil is a single-ingredient supplement in softgel form. The one active ingredient is organic coconut oil, a traditional fat extracted from coconut fruit.

The capsule also contains gelatin, medium chain triglycerides, vegetable glycerin, and titanium dioxide as inactive ingredients that help form and preserve the softgel.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: energy from medium chain triglycerides.
  • We looked for evidence on: metabolic support, fat metabolism.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for coconut oil's use in diabetes, high cholesterol, obesity, and lichen planus is not yet established in the data we hold—all four uses are rated as having insufficient reliable evidence. That doesn't mean coconut oil doesn't work for these purposes; it means the research to date hasn't been strong enough to make a solid claim one way or the other.

The evidence, ingredient by ingredient Coconut

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Coconut oil from food sources is generally well tolerated. However, concentrated supplement doses like those in softgel capsules are not well studied, so the safety notes advise getting your doctor's approval before using a high-dose coconut supplement.

The main adverse effect to watch for is allergic reaction—coconut is grouped with tree nuts for allergen purposes in the US. Reactions range from hives and skin irritation to anaphylaxis in people with coconut hypersensitivity; about half of reported oral reactions in hospital records involved anaphylaxis.

During pregnancy and lactation, coconut is rated likely safe.

Side effects, ingredient by ingredient Coconut

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Coconut.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes drug—including insulin, metformin, or any other blood sugar medication—double-check with your own doctor or pharmacist before adding this supplement. Animal data suggests coconut oil might lower blood glucose, which could increase the risk of low blood sugar if combined with your medication.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

If you don't have a nut allergy or diabetes, coconut oil softgels are generally well tolerated as a food-source supplement. If you take any diabetes medication, or if you have a tree nut allergy or history of coconut sensitivity, talk with your doctor or pharmacist before starting this product.

The same goes if you're considering it for a specific health condition—the evidence isn't solid enough yet to recommend it for diabetes, cholesterol, weight, or skin problems.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Coconut Oil, straight from the product label.

Brand GNC SuperFoods
Barcode (UPC) 048107130343
Net contents 240 Softgel(s)
Market status On market
Date entered into DSLD Mar 25, 2014
DSLD ID 31034
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Coconut Oil by GNC SuperFoods, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Softgel(s)
Maximum serving Sizes:
4 Softgel(s)
Servings per container
60
UPC/BARCODE
048107130343
IngredientAmount% DV
Calories50 {Calories}--
Calories from Fat50 {Calories}--
Total Fat5 Gram(s)8%
Protein1 Gram(s)--
Saturated Fat5 Gram(s)24%
organic Coconut Oil4000 mg--

Other ingredients: Gelatin, Medium Chain Triglycerides, Vegetable Glycerin, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

GNC SuperFoods Coconut Oil is a naturally rich source of medium chain triglycerides (MCTs), which are quickly absorbed by the body to produce energy.

CONTAINS: Tree Nuts (Coconut).

Natural source of medium chain triglycerides

General Statements

Typical Fatty Acid Profile Fatty Acid Average% Lauric Acid 38.75% Myristic Acid 13.00% Caprylic Acid 5.30% Palmitic Acid 7.50% Capric Acid 4.50% Oleic Acid 5.00% Stearic Acid 1.00% Linoleic Acid 1.00%

{softgel} ACTUAL SIZE

To ensure a complete nutritional program, take daily with these GNC products: Premium Multivitamin SuperFoods Whole Foods Blend Ultra Probiotic Complex Triple Strength Fish Oil

NEW

MCTs are hydrolyzed more rapidly and metabolized more completely than long chain fatty acids.

1,000 mg per softgel

Precautions

WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

CONTAINS: Tree Nuts (Coconut).

Formulation

No Artificial Flavors, No Artificial Sweeteners.

ORGANIC EXTRA VIRGIN

Made with organic coconut oil and naturally free of trans fat, 100% cholesterol free and manufactured to cGMP standards.

Made with organic coconut oil and naturally free of trans fat, 100% cholesterol free and manufactured to cGMP standards.

General

CODE 244303 DOG

FDA Statement of Identity

DIETARY SUPPLEMENT

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Coconut Oil by GNC SuperFoods label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Coconut Oil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Coconut Oil by GNC SuperFoods

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

1 Gram(s) per serving

Organic Coconut Oil

Interacts with
86 drugs
4000 mg per serving

Coconut is a nutritious tropical food enjoyed as oil, water, milk, and flesh, and it is generally safe to eat in normal food amounts. While some uses...

Organic Coconut Oil monograph & interactions

Other (inactive) ingredients: Gelatin, Medium Chain Triglycerides, Vegetable Glycerin, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Coconut Oil by GNC SuperFoods Drug Interactions

Want to check YOUR meds against Coconut Oil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Minor

Ingredients driving the most interactions

organic Coconut Oil 86

Individual Drug Interactions

The ingredients in Coconut Oil interact with 86 drugs. Click any drug to see the details.

1 of the 2 ingredients in Coconut Oil interact with drugs. Each result below shows which ingredient is responsible. organic Coconut Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Coconut Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Coconut Oil1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that coconut milk might increase insulin levels and/or decrease blood glucose levels.

Likelihood Unlikely Evidence D
organic Coconut Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Coconut Oil, from the product label.

GNC SuperFoods

See all GNC SuperFoods products
Name
General Nutrition Corporation
City
Pittsburgh
State
PA
ZipCode
15222
Pharmacist Counseling Corner

Coconut Oil by GNC SuperFoods: Common Questions

Does Coconut Oil by GNC SuperFoods interact with any medications?
Yes. Based on its ingredients, Coconut Oil has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Coconut Oil contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this really help with cholesterol or weight loss?
The evidence isn't established in the data we hold. Coconut oil has been studied for both, but the research so far hasn't been strong enough to make a solid claim either way.
Can I take this if I'm pregnant or breastfeeding?
Coconut is rated likely safe during pregnancy and lactation, so it's not ruled out. That said, concentrated supplement doses aren't well studied, so it's worth checking with your doctor or pharmacist for personalized advice before you start.
What if I have a tree nut allergy?
Be careful. Coconut is grouped with tree nuts for allergen labeling in the US, and allergic reactions to coconut can range from hives to anaphylaxis. If you have a nut allergy or any history of coconut sensitivity, talk with your doctor or pharmacist first.
Is coconut oil safe to take regularly?
Coconut from food is generally safe when eaten in normal amounts. High-dose concentrated supplements like these softgels aren't well studied long-term, so get your doctor's approval before using them regularly.
What's inside the capsule besides coconut oil?
The softgel also contains gelatin, medium chain triglycerides, vegetable glycerin, and titanium dioxide—these are inactive ingredients that form and stabilize the capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Coconut Oil is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Coconut Oil label
Go deeper

The Full Monographs Behind Coconut Oil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Coconut

Interacts with 86 drugs

Coconut is a nutritious tropical food enjoyed as oil, water, milk, and flesh, and it is generally safe to eat in normal food amounts. While some uses (like skin moisturizing and hydration) h...

Read the full Coconut monograph →
Sources

Sources & How We Checked

Coconut Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Coconut 10 references
  1. Teuber SS, Peterson WR. Systemic allergic reaction to coconut (Cocos nucifera) in 2 subjects with hypersensitivity to tree nut and demonstration of cross-reactivity to legumin-like seed storage proteins: new coconut and walnut food allergens. J Allergy Cl PubMed
  2. Rosado A, Fernandez-Rivas M, Gonzalez-Mancebo E, et al. Anaphylaxis to coconut. Allergy 2002;57(2):182-3. PubMed
  3. Karmakar PR, Das A, Chatterjee BP. Placebo-controlled immunotherapy with Cocos nucifera pollen extract. Int Arch Allergy Immunol 1994;103(2):194-201. PubMed
  4. Anagnostou K. Coconut Allergy Revisited. Children (Basel). 2017;4(10). pii: E85. PubMed
  5. Cifuentes L, Mistrello G, Amato S, et al. Identification of cross-reactivity between buckwheat and coconut. Ann Allergy Asthma Immunol. 2015;115(6):530-2. PubMed
  6. Michavila Gomez A, Amat Bou M, Gonzalez Cortés MV, Segura Navas L, Moreno Palanques MA, Bartolomé B. Coconut anaphylaxis: Case report and review. Allergol Immunopathol (Madr). 2015;43(2):219-20. PubMed
  7. 21CFR170.3. U.S. Food and Drug Administration Department of Health and Human Services. Updated April 1, 2017. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=170.3
  8. Alatawi KA, Alshubaily FA. Coconut products alleviate hyperglycaemic, hyperlipidimic and nephropathy indices in streptozotocin-induced diabetic wistar rats. Saudi J Biol Sci. 2021;28(8):4224-4231. PubMed
  9. Kruse L, Lor J, Yousif R, Pongracic JA, Fishbein AB. Coconut allergy: Characteristics of reactions and diagnostic predictors in a pediatric tertiary care center. Ann Allergy Asthma Immunol 2021;126(5):562-568.
  10. Pathmanandavel K, Kaur N, Joshi P, Ford LS. Anaphylaxis and allergy to coconut: An Australian pediatric case series. J Allergy Clin Immunol Pract 2020;8(10):3657-3659. PubMed

See these in context on the Coconut monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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