Interactions on record — worth a quick check against your medications. Based on 3 of 6 ingredients. Check your meds →
Dietary supplement

ConceEVE Ingredients & Drug Interactions

by Greens First Female

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

ConceEVE is a dietary supplement by Greens First Female with 6 active ingredients. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 976 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin D, L-Arginine, D-Chiro-Inositol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of ConceEVE by Greens First Female

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

ConceEVE contains 6 active ingredients designed to support female fertility and metabolic health. Folate and Vitamin D are micronutrients essential for bone health and reproductive function.

The two forms of inositol—D-Chiro-Inositol and Myoinositol—are naturally occurring compounds that research suggests may help with polycystic ovary syndrome (PCOS) and metabolic issues. L-Arginine is an amino acid that plays a role in blood vessel function and circulation.

Chaste Tree (also called Vitex) has been traditionally used in women's health formulas. The product also contains inactive ingredients—cellulose, microcrystalline cellulose, and magnesium stearate—which are common capsule fillers and binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Support reproductive health and fertility.
  • We looked for evidence on: Infertility, Dysmenorrhea, Impaired glucose tolerance (prediabetes), Metabolic syndrome, Erectile dysfunction (ED), Ovulation — and 2 related terms.
  • The strongest evidence on file: Inositol is rated "Possibly Effective" for Metabolic syndrome (Natural Medicines).
  • Also on file: Inositol is rated "Insufficient Reliable Evidence To Rate" for Diabetes, Erectile dysfunction (ED), Infertility.
  • Also on file: Vitamin D is rated "Insufficient Reliable Evidence To Rate" for Diabetes, Erectile dysfunction (ED), Dysmenorrhea.

Evidence is strongest for Vitamin D in treating rickets, osteomalacia (soft bones from vitamin D deficiency), renal bone disease, and familial hypophosphatemia—all are rated Effective. For PCOS and metabolic syndrome, the two inositol forms are rated Possibly Effective; they're also rated Possibly Effective for preventing preterm labor.

However, inositol is rated Possibly Ineffective for anxiety, diabetic nerve damage, and depression. The product facts don't include effectiveness ratings for L-Arginine, Folate, or Chaste Tree, so we can't speak to how well those ingredients work for fertility or other purposes in this formulation.

The evidence, ingredient by ingredient Inositol Vitamin D L-arginine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both inositol forms are generally well tolerated at typical doses, though some people experience mild digestive side effects like diarrhea, gas, or nausea. Vitamin D is safe at recommended amounts but can cause toxicity if you take very high doses over time—symptoms include high blood calcium levels and, in rare cases, bone loss or eye problems.

L-Arginine is often tolerated short-term but can lower blood pressure and may cause abdominal pain, bloating, nausea, diarrhea, headache, or flushing. Safety data on use during pregnancy and breastfeeding isn't fully established for inositol or L-Arginine; use either only under medical supervision.

Vitamin D is sometimes used during pregnancy at recommended doses but should be guided by your doctor. No pregnancy or breastfeeding data is on file for Folate or Chaste Tree in these product facts.

Side effects, ingredient by ingredient Inositol Vitamin D L-arginine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Inositol, L-arginine, Vitamin D.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications.
  • For scale: 977 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking ConceEVE, check with your pharmacist if you're on any of the following: blood pressure medications (especially ACE inhibitors or ARBs), calcium channel blockers like verapamil or diltiazem for heart rhythm, thiazide diuretics, digoxin or other heart rhythm drugs, atorvastatin or other statins, blood thinners or antiplatelet drugs, antidiabetes medications, potassium-sparing diuretics, sildenafil (Viagra), or isoproterenol. These are the drug types most likely to interact with ingredients in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

ConceEVE is a fertility-support formula best suited for people without significant heart conditions, uncontrolled high blood pressure, or diabetes requiring medication—especially those on blood thinners or potassium-sparing diuretics. If you take any prescription medications, blood pressure drugs, heart rhythm medications, statins, diabetes drugs, or blood thinners, check your exact medications with the tool on this page before starting.

Talk to your pharmacist or doctor about whether this product is right for your health situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ConceEVE, straight from the product label.

Brand Greens First Female
Barcode (UPC) 853367008604
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 312880
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Girls: (All), Adult Female (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ConceEVE by Greens First Female, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
60
UPC/BARCODE
853367008604
IngredientAmount% DV
Folate150 mcg DFE38%
Calories10 Calorie(s)--
Total Carbohydrate2 Gram(s)1%
D-Chiro-Inositol50 mg--
Vitamin D5 mcg25%
Myoinositol1.5 Gram(s)--
L-Arginine250 mg--
Chaste Tree, Powder250 mg--

Other ingredients: Cellulose, Microcrystalline Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

May improve insulin utilization for improved ovulation Promotes healthy ovarian function Promotes healthy, natural ovulation Supports regular menstrual cycles

ConceEVE is a breakthrough, multi-functional, all natural fertility nutritional formula, which helps support reproductive health. ConceEVE is recommended and formulated by leading OB/GYN's based on the scientific evidence that certain nutrients may optimize and support the fertility process. Difficulties conceiving can occur for a variety of reasons including hormonal imbalances, menstrual irregularites and Polycystic Ovary Syndrome (PCOS). Clinical studies show that the nutrients found in ConceEVE may improve several critical pathways that lead to conception. ConceEVE is the most unique, potent nutritional formula available for fertility support with clinically-proven active ingredients that help regulate specific biological processes.

Reproductive support capsules Promotes healthy ovarian function & ovulation while supporting regular menstrual cycles

No GMO No Dairy No Sugar No Gluten No Soy No Artificial sweeteners

Formula

Natural Folate: Supports progesterone levels and improves glucose metabolism Myo-Inositol: Supports menstrual cycles and ovulation L-Arginine: Supports blood circulation to uterus, aids in production of cervical mucous Chasteberry: Supports hormonal balance, reduces inflammation associated with PCOS D-Chiro Inositol: Supports ovulatory function, increases quality of eggs released during ovulation cycle.

Precautions

Keep out of the reach of children.

Do not purchase if safety seal is broken or missing.

Storage

Protect from heat, light and moisture.

Store at 15-30 degrees C (59-86 degrees F).

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Copyright 2022 Ceautamed Worldwide, LLC. All rights reserved.

Quatrefolic is a registered trademark of Gnosis USA Inc.

FDA Statement of Identity

Dietary Supplements

Suggested/Recommended/Usage/Directions

Directions for use: Adults take 3 capsules daily, preferably with a meal, or as recommended by a physician. The benefits of ConceEVE increase with use over time. For best results, repeat daily for at least 3 consecutive months.

See for yourself

ConceEVE by Greens First Female label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in ConceEVE by Greens First Female

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Folate

150 mcg DFE per serving Form: Quatrefolic

D-Chiro-Inositol

Interacts with
86 drugs
50 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

D-Chiro-Inositol monograph & interactions

Vitamin D

Interacts with
715 drugs
5 mcg per serving Form: Cholecalciferol

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...

Vitamin D monograph & interactions

Myoinositol

Interacts with
86 drugs
1.5 Gram(s) per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Myoinositol monograph & interactions

L-Arginine

Interacts with
403 drugs
250 mg per serving

L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen. It is popularly used for bl...

L-Arginine monograph & interactions

Chaste Tree, Powder

250 mg per serving

Other (inactive) ingredients: Cellulose, Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

ConceEVE by Greens First Female Drug Interactions

Want to check YOUR meds against ConceEVE?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
976Drugs
411 Moderate 565 Minor

Ingredients driving the most interactions

Vitamin D 715

Each ingredient & the kinds of drugs it affects

For each ingredient in ConceEVE with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin D8 drug types · 715 drugs

Aluminum

Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.

Likelihood Probable Evidence B
Atorvastatin (Lipitor)

Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.

Likelihood Probable Evidence B
Calcipotriene (Dovonex)

Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.

Likelihood Probable Evidence D
Digoxin (Lanoxin)

Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.

Likelihood Possible Evidence D
Diltiazem (Cardizem, Others)

Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.

Likelihood Probable Evidence B
Thiazide Diuretics

Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.

Likelihood Probable Evidence D
Verapamil (Calan, Others)

Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.

Likelihood Possible Evidence D

L-Arginine9 drug types · 403 drugs

Ace Inhibitors (Aceis)

Theoretically, concomitant use of L-arginine and ACE inhibitors may increase the risk for hypotension and hyperkalemia.
Combining L-arginine with some antihypertensive drugs, especially ACE inhibitors, seems to have additive vasodilating and blood pressure-lowering effects. Furthermore, ACE inhibitors can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ACE inhibitors with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Angiotensin Receptor Blockers (Arbs)

Theoretically, concomitant use of L-arginine and ARBs may increase the risk of hypotension and hyperkalemia.
L-arginine increases nitric oxide, which causes vasodilation. Combining L-arginine with ARBs seems to increase L-arginine-induced vasodilation. Furthermore, ARBs can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ARBs with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of L-arginine with anticoagulant and antiplatelet drugs might have additive effects and increase the risk of bleeding.
Preliminary research suggests that L-arginine infusions reduce platelet aggregation in humans. The clinical significance of this effect is unclear.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of L-arginine might have additive effects with antidiabetes drugs.
Preliminary clinical research shows that L-arginine decreases blood glucose levels in patients with type 2 diabetes.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of L-arginine and antihypertensive drugs may increase the risk of hypotension.
L-arginine increases nitric oxide, which causes vasodilation. Clinical evidence shows that L-arginine can reduce blood pressure in some individuals with hypertension. Furthermore, combining L-arginine with some antihypertensive drugs seems to have additive vasodilating and blood pressure-lowering effects.

Likelihood Probable Evidence D
Isoproterenol (Isuprel)

Theoretically, concurrent use of isoproterenol and L-arginine might result in additive effects and hypotension.
Preliminary clinical evidence suggests that L-arginine enhances isoproterenol-induced vasodilation in patients with essential hypertension or a family history of essential hypertension.

Likelihood Probable Evidence D
Potassium-Sparing Diuretics

Theoretically concomitant use of potassium-sparing diuretics with L-arginine may increases the risk of hyperkalemia.
Potassium-sparing diuretics can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients.

Likelihood Possible Evidence D
Sildenafil (Viagra)

Theoretically, concurrent use of sildenafil and L-arginine might increase the risk for hypotension.
In vivo, concurrent use of L-arginine and sildenafil has resulted in increased vasodilation. Theoretically, concurrent use might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
Testosterone

Theoretically, concomitant use of L-arginine and testosterone might have additive effects.
In clinical research, L-arginine increases the level of testosterone in male patients with erectile dysfunction. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D

D-Chiro-Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
The maker

Brand information

Manufacturer and brand details for ConceEVE, from the product label.

Greens First Female

See all Greens First Female products
Name
Ceautamed Worldwide, LLC
Street Address
1289 Clint Moore Road
City
Boca Raton
State
FL
ZipCode
33487
Phone Number
866-409-6262
Web Address
GreensFirst.com
Pharmacist Counseling Corner

ConceEVE by Greens First Female: Common Questions

Does ConceEVE by Greens First Female interact with any medications?
Yes. Based on its ingredients, ConceEVE has a known interaction with 976 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
ConceEVE contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take ConceEVE if I'm trying to get pregnant?
This product is designed as a fertility support formula, and both inositol forms are rated Possibly Effective for PCOS and metabolic syndrome—common fertility concerns. However, safety data for pregnancy and breastfeeding isn't fully established. Talk with your doctor or pharmacist to make sure it's right for your individual situation.
What does the inositol in this product do?
Inositol is a compound that helps regulate blood sugar and may support ovarian health. This product contains two forms—D-Chiro-Inositol and Myoinositol—that research suggests may help with PCOS and metabolic syndrome, and possibly help prevent preterm labor. The most common side effects are mild digestive issues like diarrhea, gas, or nausea.
Does this supplement have any side effects?
The most common side effects come from the inositol forms and L-Arginine: digestive symptoms (diarrhea, gas, nausea, bloating, abdominal pain) and occasionally headache or flushing. Vitamin D is well tolerated at recommended doses but can cause problems at very high doses over time. Most people tolerate this product well.
Can I take this if I'm on blood pressure medication?
L-Arginine in this product can theoretically lower blood pressure and may have additive effects with blood pressure drugs, raising your risk of low blood pressure. This is especially important if you're on ACE inhibitors or ARBs. Check with your pharmacist before starting.
Will this affect my diabetes medication?
Both inositol forms can lower blood sugar, and there's a theoretical risk of low blood sugar (hypoglycemia) if you're already taking antidiabetes drugs. L-Arginine may also have additive blood-sugar-lowering effects. Talk to your doctor or pharmacist before adding this product to your routine.
What is Chaste Tree in this formula, and does it interact with anything?
Chaste Tree (Vitex) is a traditional herbal ingredient used in women's health formulas. We don't hold interaction data for it, so we can't say which medications it may or may not affect. Ask your pharmacist if you're concerned about interactions with your current medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ConceEVE label
Sources

Sources & How We Checked

ConceEVE's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 106 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Vitamin D 26 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Tatro DS, ed. Drug Interactions Facts. Facts and Comparisons Inc., St. Louis, MO. 1999.
  3. Koutkia P, Chen TC, Holick MF. Vitamin D intoxication associated with an over-the-counter supplement. N Engl J Med 2001;345:66-7. PubMed
  4. Bar-Or D, Yoel G. Calcium and calciferol antagonize effect of verapamil in atrial fibrillation. Br Med J 1981;282:1585-6.
  5. Demontis R, Leflon A, Fournier A, et al. 1 alpha(OH) vitamin D3 increases plasma aluminum in hemodialyzed patients taking AI(OH)3. Clin Nephrol 1986;26:146-9.
  6. Crowe M, Wollner L, Griffiths RA. Hypercalcemia following vitamin D and thiazide therapy in the elderly. Practitioner 1984;228:312-3.
  7. Parfitt AM. Thiazide-induced hypercalcemia in vitamin D-treated hypoparathyroidism. Ann Intern Med 1972;77:557-63. PubMed
  8. Thiazide diuretics and the risk of osteoporosis. Pharmacist's Letter/Prescriber's Letter 2003;19(11):191105.
  9. Moon J. The role of vitamin D in toxic metal absorption. J Am Coll Nutr 1994;13:559-64.
  10. Demontis R, Reissi D, Noel C, et al. Indirect clinical evidence that 1alphaOH vitamin D<SUB>3</SUB> increases the intestinal absorption of aluminum. Clin Nephrol 1989;31:123-7.
  11. Adler AJ, Berlyne GM. Duodenal aluminum absorption in the rat: effect of vitamin D. Am J Physiol 1985;249:G209-13. PubMed
  12. Schwartz JB. Effects of vitamin D supplementation in atorvastatin-treated patients: A new drug interaction with an unexpected consequence. Clin Pharmacol Ther 2009;85:198-203. PubMed
  13. Dietary reference intakes for calcium and vitamin D. Institute of Medicine, November 30, 2010. Available at: http://www.iom.edu/~/media/Files/Report%20Files/2010/Dietary-Reference-Intakes-for-Calcium-and-Vitamin-D/Vitamin%20D%20and%20Calcium%202010%20Repo
  14. Cox KA, Dunn MA. Aluminum toxicity alters the regulation of calbindin-D28k protein and mRNA expression in chick intestine. J Nutr 2001;131:2007-13. PubMed
  15. Escribano, J., Balaguer, A., Pagone, F., Feliu, A., and Roque, I. Figuls. Pharmacological interventions for preventing complications in idiopathic hypercalciuria. Cochrane.Database.Syst.Rev. 2009;(1):CD004754. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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