Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Cordyceps+ Ingredients & Drug Interactions

by Lifecykel

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Cordyceps+ is a dietary supplement by Lifecykel with 3 active ingredients. Its ingredients are commonly taken for fatigue and low energy, athletic performance and stamina, respiratory and lung support.Based on those ingredients, 249 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coryceps Mycelium Extract, Kakadu Plum. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Cordyceps+ by Lifecykel

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1,012 mg) without saying how much of each component you get.

Cordyceps+ contains 3 active ingredients: two forms of cordyceps (mycelium extract and fruiting body extract) and kakadu plum. Cordyceps is a fungal ingredient traditionally used in supplements, while kakadu plum is a concentrated extract from the fruit.

The product is a liquid suspension in water and alcohol.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: Energy, stamina, and athletic performance support.
  • We looked for evidence on: Athletic performance, Fatigue, Endurance, Physical stamina.
  • The closest evidence on file: Cordyceps is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Cordyceps is rated "Insufficient Reliable Evidence To Rate" for Fatigue.

Evidence for cordyceps is mixed. For athletic performance, the data suggests it's possibly ineffective — don't expect it to boost your workout.

For sexual dysfunction, asthma, arrhythmia, lung cancer, and COPD, there isn't enough reliable evidence to rate whether it works. Kakadu plum has possibly effective evidence for constipation relief, but insufficient evidence for bone health, cholesterol, or hepatitis.

The evidence, ingredient by ingredient Cordyceps Plum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both cordyceps extracts are generally well tolerated for short-term use (up to one year), but the evidence is limited and product quality varies widely. The most common side effects are mild gastrointestinal ones — abdominal discomfort, constipation, or diarrhea — and these are uncommon.

Symptoms can often be reduced by taking it with food. There's a rare case report of liver inflammation (hepatitis) possibly linked to a cordyceps product, though it's unclear whether cordyceps or a contaminant was responsible.

Kakadu plum is well tolerated and causes mainly minor gastrointestinal effects like gas and diarrhea; serious adverse effects such as allergic reactions or bowel obstruction are rare. For pregnancy: there isn't enough safety data for cordyceps, so it's best avoided.

The same applies to breastfeeding — concentrated cordyceps supplements lack safety data. Kakadu plum as food is generally fine during pregnancy, but concentrated supplement forms haven't been well studied.

Side effects, ingredient by ingredient Cordyceps Plum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Cordyceps, Plum.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 249 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist if you take blood thinners or antiplatelet drugs (like warfarin, aspirin, or clopidogrel) — both cordyceps and kakadu plum may increase bleeding risk. Also double-check if you take immunosuppressants (used after transplants or for autoimmune conditions) or testosterone therapy before adding this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take blood thinners, immunosuppressants, or testosterone, talk to your pharmacist before starting this product — the interactions are documented. Cordyceps+ is generally well tolerated for short-term use, but evidence for most of its claimed benefits is limited or absent.

Consider it mainly if you're interested in traditional use and have checked it against your medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cordyceps+, straight from the product label.

Brand Lifecykel
Barcode (UPC) 0793591581804
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 320386
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cordyceps+ by Lifecykel, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
2 mL
Servings per container
30
UPC/BARCODE
0793591581804
IngredientAmount% DV
Proprietary Blend1012 mg--
Coryceps Mycelium Extract0 NP--
Cordyceps Fruiting Body Extract0 NP--
Kakadu Plum0 NP--

Other ingredients: Water, Filtered, Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Wild harvested kakadu plum natural flavor Full spectrum liquid extract

U.S. Grown Mushrooms

This product contains naturally occurring sulphur.

Formulation

Proudly made in the USA.

Vegan friendly

Gluten free Non GMO

General Statements

Realize your potential

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FDA Statement of Identity

Dietary Supplement

Precautions

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Caution: Contains mushrooms. Do not use if sensitive to mushrooms.

Do not exceed recommended dose. If an excessive amount is accidentally swallowed or in the event of an adverse reaction, stop use and seek medical attention immediately.

Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before use.

Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before use.

Storage

Store in a cool, dark place or refrigerate.

Suggested/Recommended/Usage/Directions

Directions for use: As a dietary supplement, take 2 ml per day. Avoid contact with eyes. Shake well before using.

See for yourself

Cordyceps+ by Lifecykel label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Cordyceps+ by Lifecykel

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

1012 mg per serving

Other (inactive) ingredients: Water, Filtered, Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cordyceps+ by Lifecykel Drug Interactions

Want to check YOUR meds against Cordyceps+?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
249Drugs
241 Moderate 8 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Cordyceps+ with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Coryceps Mycelium Extract3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D

Kakadu Plum1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, plum juice might have antiplatelet effects.
Consuming plum juice while taking anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding. In healthy volunteers, drinking plum juice 200 mL daily for 28 days prolonged clotting time and inhibited platelet aggregation.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Cordyceps+, from the product label.

Lifecykel

See all Lifecykel products
Name
Lifecykel Labs, LLC.
Street Address
880 Frontage Rd.
City
Peshtigo
State
WI
ZipCode
54157
Web Address
lifecykel.com
Pharmacist Counseling Corner

Cordyceps+ by Lifecykel: Common Questions

Does Cordyceps+ by Lifecykel interact with any medications?
Yes. Based on its ingredients, Cordyceps+ has a known interaction with 249 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cordyceps+ contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Cordyceps+ if I'm pregnant?
The cordyceps extracts don't have enough safety data in pregnancy, so they're best avoided. Kakadu plum as a food is generally fine, but the concentrated supplement form hasn't been well studied either. Talk to your OB or pharmacist for personalized advice.
Does cordyceps actually boost athletic performance?
The evidence suggests it's possibly ineffective for athletic performance, so don't count on it to improve your workouts.
What are the most common side effects?
Mild gastrointestinal effects — abdominal discomfort, constipation, or diarrhea — are the most common, and they're uncommon overall. Taking it with food can help reduce these.
Is kakadu plum effective for anything?
Kakadu plum has possibly effective evidence for constipation relief. For bone health, cholesterol, and liver issues, there isn't enough reliable evidence to say whether it works.
Can I take this with my blood thinner?
Don't start this product if you're on a blood thinner without checking with your pharmacist first. Both cordyceps and kakadu plum may theoretically increase bleeding risk, though it hasn't been confirmed in humans.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cordyceps+ is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cordyceps+ label
Sources

Sources & How We Checked

Cordyceps+'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cordyceps 14 references
  1. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
  2. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med 1998;4:429-57.
  3. Chen YJ, Shiao MS, Lee SS, Wang SY. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. Life Sci 1997;60:2349-59. PubMed
  4. Zhao Y. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;71:612-5, 42.
  5. Chen GZ, Chen GL, Sun T, et al. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Chin Med J (English) 1991;104:4-8.
  6. Zhu XY, Yu HY. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454.
  7. Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sci 9-5-2003;73(16):2127-2136. PubMed
  8. Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Yakugaku Zasshi 1991;111(9):504-509. PubMed
  9. Wu, T. N., Yang, K. C., Wang, C. M., Lai, J. S., Ko, K. N., Chang, P. Y., and Liou, S. H. Lead poisoning caused by contaminated Cordyceps, a Chinese herbal medicine: two case reports. Sci.Total Environ. 4-5-1996;182(1-3):193-195. PubMed
  10. Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). Cochrane Database Syst Rev. 2015;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2.
  11. Zhang HW, Lin ZX, Tung YS, Kwan TH, Mok CK, Leung C, Chan LS. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease (Review). Cochrane Database Syst Rev. 2014;(12):CD008353. doi: 10.1002/14651858.CD008353.pub2. PubMed
  12. Bee Yean O, Zoriah A. Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis. J Tradit Chin Med. 2019;39(1):1-14.
  13. Thurian D, Montani M, Stickel F. Drug-induced, mixed-type hepatitis following ingestion of Cordyceps sinensis. Int J Clin Pharmacol Ther 2022;60(2):115-120. PubMed
  14. Yu X, Mao Y, Shergis JL, et al. Effectiveness and safety of oral Cordyceps sinensis on stable COPD of GOLD stages 2-3: Systematic review and meta-analysis. Evid Based Complement Alternat Med. 2019;2019:4903671.

See these in context on the Cordyceps monograph →

Plum 10 references
  1. Lever E, Cole J, Scott SM, Emery PW, Whelan K. Systematic review: the effect of prunes on gastrointestinal function. Aliment Pharmacol Ther. 2014;40(7):750-8. PubMed
  2. Hooshmand S, Chai SC, Saadat RL, et al. Comparative effects of dried plum and dried apple on bone in postmenopausal women. Br J Nutr. 2011;106(6):923-30. PubMed
  3. Ibrahim N, Chauhan I, Nikkar-Esfahani A. 'A problematic plum pit in the piping': a case of traumatic oesophageal perforation. BMJ Case Rep. 2016;2016. pii: bcr2015213807. PubMed
  4. Piirainen L, Peuhkuri K, Bäckström K, Korpela R, Salminen S. Prune juice has a mild laxative effect in adults with certain gastrointestinal symptoms. Nutr. Res. 2007;27(8):511-3. DOI
  5. Kong MS, Wang KL. A prune-induced small intestinal obstruction: sonographic appearance. J Clin Ultrasound. 1995;23(9):558-60. PubMed
  6. Jain M, Pielage P, De-Ryke R. Plum stones: an unusual cause of ileostomy obstruction demonstrated by sonography. J Clin Ultrasound. 1998;26(8):416-7. DOI
  7. Arjmandi BH, Khalil DA, Lucas EA, et al. Dried plums improve indices of bone formation in postmenopausal women. J Womens Health Gend Based Med. 2002;11(1):61-8. PubMed
  8. Santhakumar AB, Kundur AR, Fanning K, Netzel M, Stanley R, Singh I. Consumption of anthocyanin-rich Queen Garnet plum juice reduces platelet activation related thrombogenesis in healthy volunteers. J. Functional Foods. 2015;12:11-22. DOI
  9. Santhakumar AB, Kundur AR, Sabapathy S, Stanley R, Singh I. The potential of anthocyanin-rich Queen Garnet plum juice supplementation in alleviating thrombotic risk under induced oxidative stress conditions. J. Functional Foods. 2015;14:747-57. DOI
  10. Johnson MC, Fisher JK. Plum pit ileus: a case report. Mo Med. 1991;88(10):696-8.

See these in context on the Plum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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