Major interaction on record — check this product against your medications before combining. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Cordyceps Mushroom Extract Ingredients & Drug Interactions

by Z Natural Foods

Cordyceps Mushroom Extract label
See full label image
Other (e.g. Tea Bag) Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cordyceps Mushroom Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Cordyceps Mushroom Extract is a dietary supplement by Z Natural Foods with 3 active ingredients. Its ingredients are commonly taken for energy and cellular function support, athletic performance and muscle energy, circulation support.Based on those ingredients, 47 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Adenosine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Cordyceps Mushroom Extract by Z Natural Foods

Ask about any prescription or over-the-counter medication and we check it for interactions with Cordyceps Mushroom Extract by Z Natural Foods — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cordyceps Mushroom Extract by Z Natural Foods

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Cordyceps Mushroom Extract by Z Natural Foods has 3 active ingredients: polysaccharides, cordycepic acid, and adenosine. The product also contains cordyceps extract powder as an inactive ingredient.

The polysaccharides and cordycepic acid are compounds extracted from the cordyceps mushroom itself; adenosine is a nucleoside that plays a role in cellular energy and signaling.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Adenosine's overall clinical evidence instead.

Strong

Strong clinical evidence supports Adenosine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Cardiovascular disease diagnosis — rated "Effective" (Natural Medicines).
  • On file: Paroxysmal supraventricular tachycardia — rated "Effective" (Natural Medicines).
  • On file: Cachexia — rated "Possibly Effective" (Natural Medicines).

The effectiveness data we hold applies to adenosine when given by injection for specific heart conditions — paroxysmal supraventricular tachycardia (a rapid irregular heartbeat) and cardiovascular disease diagnosis — where it is rated effective. We have no effectiveness information on file for cordyceps mushroom extract as an oral supplement, polysaccharides, or cordycepic acid for any condition.

The evidence, ingredient by ingredient Adenosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Adenosine as a prescription injection is powerful and must be given only by medical professionals — the oral or supplement form has limited safety evidence. Safety data for oral adenosine supplement use is insufficient, so it's best avoided.

Safety has not been established for use while breastfeeding, so breastfeeding should be avoided while taking this product. The prescription injectable form of adenosine can cause chest pain, dizziness, shortness of breath, flushing, headache, low blood pressure, nausea, and in rare cases arrhythmias or cardiac arrest — though oral use has not reported adverse effects, a thorough safety evaluation has not been done.

Side effects, ingredient by ingredient Adenosine

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Adenosine.
  • The most serious interaction on file is rated Major.
  • For scale: 47 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Stop and check with your doctor or pharmacist before taking this if you use dipyridamole (Major interaction — can cause dizziness, slow heart rate, or fainting), carbamazepine (Moderate — increased risk of heart block), or caffeine, theophylline, or aminophylline products (Minor — may reduce this product's effects).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.

This product contains adenosine, a compound used medically for cardiac testing and heart rhythm problems, but the supplement form has limited safety data. If you take dipyridamole, carbamazepine, or caffeine-containing products, talk with your doctor or pharmacist before using this — interactions can be serious.

Avoid it while breastfeeding unless your doctor advises otherwise.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cordyceps Mushroom Extract, straight from the product label.

Brand Z Natural Foods
Barcode (UPC) 616983440490
Net contents 1 Pound(s); 454 Gram(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 299847
Product type Other Combinations
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cordyceps Mushroom Extract by Z Natural Foods, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2.8 Gram(s)
Maximum serving Sizes:
2.8 Gram(s)
Servings per container
161
UPC/BARCODE
616983440490
IngredientAmount% DV
Calories0 Calorie(s)--
Polysaccharides0.7 Gram(s)--
Cordycepic Acid0.3 Gram(s)--
Adenosine8.4 mg--

Other ingredients: Cordyceps Extract, Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

The powerful benefits of eating codyceps were initially recognized 1,500 years ago in Tibet. Shepherd farmers notice a significant difference in their cattle; they had become quite energetic after eating a small mushroom. This mushroom is what we now know as the Cordyceps Mushroom and is widely used for healthy vitality levels.

EarthKosher

Suggested/Recommended/Usage/Directions

Suggested use: Take 1 teaspoon twice daily. Sprinkle on entrees, soups or add to smoothies or teas.

Formulation

Grown and extracted in China Packaged with care in Florida, USA

Non GMO Gluten free Chemical free

Vegan

Seals/Symbols

EarthKosher

Precautions

California Prop 65 Warning: Cancer and Reproductive Harm - www.P65Warnings.ca.gov/food

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cordyceps Mushroom Extract by Z Natural Foods label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cordyceps Mushroom Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cordyceps Mushroom Extract by Z Natural Foods

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2.8 Gram(s) Dosage formOther (e.g. Tea Bag) Servings per container161 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Polysaccharides

0.7 Gram(s) per serving

Cordycepic Acid

0.3 Gram(s) per serving

Adenosine

Interacts with
47 drugs
8.4 mg per serving

Adenosine is a natural building block your body uses for energy and cell signaling, and a prescription injectable version is used by doctors to treat...

Adenosine monograph & interactions

Other (inactive) ingredients: Cordyceps Extract, Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cordyceps Mushroom Extract by Z Natural Foods Drug Interactions

Want to check YOUR meds against Cordyceps Mushroom Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
47Drugs
2 Major 1 Moderate 44 Minor

Ingredients driving the most interactions

Adenosine 47

Individual Drug Interactions

The ingredients in Cordyceps Mushroom Extract interact with 47 drugs. Click any drug to see the details.

1 of the 3 ingredients in Cordyceps Mushroom Extract interact with drugs. Each result below shows which ingredient is responsible. Adenosine

Each ingredient & the kinds of drugs it affects

For each ingredient in Cordyceps Mushroom Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Adenosine3 drug types · 47 drugs

Dipyridamole (Persantine)

Dipyridamole can increase the therapeutic and toxic effects of adenosine.
Dipyridamole decreases the metabolism of adenosine. Intravenous infusion of adenosine in patients who are taking dipyridamole can cause dizziness, bradycardia, and syncope. Dipyridamole should be discontinued for several days prior to a cardiac stress test using adenosine.

Likelihood Likely Evidence D
Carbamazepine (Tegretol)

Carbamazepine might increase the risk of heart block when used concomitantly with adenosine.
Carbamazepine and adenosine can both cause heart block. Giving them concurrently might produce an additive effect.

Likelihood Possible Evidence D
Methylxanthines

Methylxanthines are competitive antagonists of adenosine and can block its pharmacologic effects.
The methylxanthines, aminophylline, caffeine, and theophylline, can block the effects of adenosine by acting as competitive antagonists at adenosine cell surface receptors. It is recommended that methylxanthines be avoided for 24 hours prior to cardiac stress tests.

Likelihood Possible Evidence D
Adenosine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cordyceps Mushroom Extract, from the product label.

Z Natural Foods

See all Z Natural Foods products
Name
Z Natural Foods
Street Address
5407 N Haverhill Rd Ste 336
City
West Palm Beach
State
FL
ZipCode
33407
Web Address
www.ZNaturalFoods.com
Pharmacist Counseling Corner

Cordyceps Mushroom Extract by Z Natural Foods: Common Questions

Does Cordyceps Mushroom Extract by Z Natural Foods interact with any medications?
Yes. Based on its ingredients, Cordyceps Mushroom Extract has a known interaction with 47 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cordyceps Mushroom Extract contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Cordyceps with my dipyridamole for my heart?
No — this is a Major interaction. Adenosine in this product can amplify dipyridamole's effects and cause dizziness, slow heart rate, and fainting. Talk to your doctor before combining them. If you need an adenosine-based stress test, dipyridamole must be stopped several days beforehand.
What's the difference between this supplement and the adenosine my cardiologist mentioned?
The adenosine used in hospitals is given by IV injection under careful medical supervision for heart rhythm problems and cardiac stress testing — it's very powerful. This product is an oral supplement form, which has not been thoroughly studied for safety in that way.
Can I take this while I'm breastfeeding?
No — safety has not been established for breastfeeding, so it should be avoided. Talk with your doctor or pharmacist for personalized advice.
Will caffeine interfere with this cordyceps product?
Yes — caffeine, theophylline, and aminophylline are competitive blockers of adenosine and can reduce this product's effects. If you drink coffee, tea, or take these medications, avoid them for 24 hours before or after use.
Does this product work for anything?
The only effectiveness data we have on file applies to adenosine when injected for heart rhythm problems and cardiac testing — not to oral cordyceps supplement use. Evidence for cordyceps mushroom extract itself is not established in the data we hold.
What are the side effects of taking this orally?
No adverse effects have been reported from oral or intramuscular adenosine, though a thorough safety evaluation hasn't been done. The prescription IV form can cause chest pain, dizziness, shortness of breath, flushing, headache, and low blood pressure.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cordyceps Mushroom Extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cordyceps Mushroom Extract label
Go deeper

The Full Monographs Behind Cordyceps Mushroom Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Adenosine

Interacts with 47 drugs

Adenosine is a natural building block your body uses for energy and cell signaling, and a prescription injectable version is used by doctors to treat certain fast heart rhythms. As an over-t...

Read the full Adenosine monograph →
Sources

Sources & How We Checked

Cordyceps Mushroom Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Adenosine 10 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Agteresch HJ, Dagnelie PC, van den Berg JW, Wilson JH. Adenosine triphosphate: established and potential clinical applications. Drugs 1999;58:211-32.. PubMed
  3. Agteresch HJ, Dagnelie PC, van der Gaast A, et al. Randomized clinical trial of adenosine 5'-triphosphate in patients with advanced non-small-cell lung cancer. J Natl Cancer Inst 2000;92:321-8.. PubMed
  4. Haskell CM, Wong M, Williams A, Lee LY. Phase I trial of extracellular adenosine 5'-triphosphate in patients with advanced cancer. Med Pediatr Oncol 1996;27:165-73.. DOI
  5. Haskell CM, Mendoza E, Pisters KM, et al. Phase II study of intravenous adenosine 5'-triphosphate in patients with previously untreated stage IIIB and stage IV non-small cell lung cancer. Invest New Drugs 1998;16:81-5.. PubMed
  6. Eisenach JC, Curry R, Hood DD. Dose response of intrathecal adenosine in experimental pain and allodynia. Anesthesiology 2002;97:938-42.. PubMed
  7. Agteresch HJ, Dagnelie PC, Rietveld T, et al. Pharmacokinetics of intravenous ATP in cancer patients. Eur J Clin Pharmacol 2000;56:49-55.. PubMed
  8. Underwood DA. Which medications should be held before a pharmacologic or exercise stress test? Cleve Clin J Med 2002;69:449-50. PubMed
  9. Litmann L, Anderson JD, Monroe MH. Adenosine and Aggrenox: A hazardous combination. Ann Intern Med 2002;137:E-76. PubMed
  10. Faghihi G, Iraji F, Rajaee Harandi M, et al. Comparison of the efficacy of topical minoxidil 5% and adenosine 0.75% solutions on male androgenic alopecia and measuring patient satisfaction rate. Acta Dermatovenerol Croat 2013;21(3):155-9.

See these in context on the Adenosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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