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Dietary supplement

Corn Silk Ingredients & Drug Interactions

by NusaPure

Corn Silk label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Corn Silk against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Corn Silk is a dietary supplement by NusaPure with 1 active ingredient. Its ingredients are commonly taken for urinary tract and bladder problems, mild fluid retention (diuretic), kidney and prostate concerns.Based on those ingredients, 290 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Corn Silk Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Corn Silk by NusaPure

Ask about any prescription or over-the-counter medication and we check it for interactions with Corn Silk by NusaPure — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Corn Silk by NusaPure

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

NusaPure Corn Silk is a single–ingredient capsule: corn silk extract. Corn silk (the threads you pull off an ear of corn) has been used traditionally in herbal medicine.

The capsules also contain inactive ingredients — cellulose, silica, magnesium stearate, and rice flour — which are fillers and binders that hold the capsule together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Corn Silk's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Urinary tract and bladder health support.
  • We looked for evidence on: Nocturnal enuresis, Prostatitis, Urinary tract infections (UTIs), Urinary irritation, Fluid retention, Kidney health.
  • The closest evidence on file: Corn Silk is rated "Insufficient Reliable Evidence To Rate" for Prostatitis (Natural Medicines).
  • Also on file: Corn Silk is rated "Insufficient Reliable Evidence To Rate" for Urinary tract infections (UTIs), Nocturnal enuresis.

The evidence for corn silk extract's effectiveness is limited. We hold insufficient reliable evidence to rate it for angina, cardiovascular disease, congestive heart failure, depression, diabetes, or fatigue.

While animal and human studies suggest corn silk may lower blood pressure and blood sugar, clinical evidence for treating these conditions as a supplement isn't established in our data.

The evidence, ingredient by ingredient Corn Silk

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Corn silk extract is generally well tolerated for short-term use, but human safety data are limited. The most common adverse effects reported with oral use are low potassium and low sodium, especially with prolonged use.

One important note: there isn't enough reliable safety data during pregnancy, so it's best avoided. While breastfeeding, safety is unknown — talk with your doctor or pharmacist before using it.

Side effects, ingredient by ingredient Corn Silk

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Corn Silk.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 290 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking NusaPure Corn Silk, check with your pharmacist if you take blood pressure–lowering medications, water pills (diuretics), corticosteroids, diabetes medications, or warfarin. All of these have documented Moderate-severity interactions with corn silk extract.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Corn silk extract may appeal to you if you're interested in traditional herbal support, but the evidence for its effectiveness isn't well established in our data. If you take blood pressure medications, water pills, diabetes drugs, corticosteroids, or warfarin, you'll need to check with your pharmacist first — the interactions are real and could affect how those medications work.

Talk to us before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Corn Silk, straight from the product label.

Brand NusaPure
Barcode (UPC) X002WATLMP
Net contents 200 Veg Cap(s)
Market status On market
Date entered into DSLD Nov 22, 2022
DSLD ID 274947
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Corn Silk by NusaPure, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
200
UPC/BARCODE
X002WATLMP
IngredientAmount% DV
Corn Silk Extract150 mg--

Other ingredients: Cellulose, Silica, Magnesium Stearate, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: For adults, take one (1) capsule daily, preferably with meals or as directed by a healthcare professional.

Precautions

Warning: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, or individuals with a known medical condition should consult a physician before using this or any other dietary supplement.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Allergen Information: Not manufactured with artificial coloring, artificial flavors, yeast, milk, or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, egg, wheat, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Storage

Store in a cool dry place. Avoid excessive heat or moisture.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Premium Quality Assembled in USA Gluten Free FDA Registered Facility

Manufactured in a cGMP Inspected Facility

Formulation

GMO Free Made with Non-GMO Ingredients Gluten Free FDA Registered Facility

Assembled in USA Natural Traditional Herb Supports normal urinary function Support for cardiovascular health

Max Strength

Allergen Information: Not manufactured with artificial coloring, artificial flavors, yeast, milk, or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, egg, wheat, fish, shellfish or tree nut ingredients.

Natural color variation may occur in this product.

General Statements

Corn Silk 3000 mg equivalent per capsule

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Corn Silk by NusaPure label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Corn Silk label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Corn Silk by NusaPure

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container200 Amounts shown are per serving.

Corn Silk Extract

Interacts with
290 drugs
150 mg per serving Form: Zea mays

Corn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence...

Corn Silk Extract monograph & interactions

Other (inactive) ingredients: Cellulose, Silica, Magnesium Stearate, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Corn Silk by NusaPure Drug Interactions

Want to check YOUR meds against Corn Silk?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
290Drugs
290 Moderate

Ingredients driving the most interactions

Corn Silk Extract 290

Individual Drug Interactions

The ingredients in Corn Silk interact with 290 drugs. Click any drug to see the details.

1 of the 1 ingredient in Corn Silk interact with drugs. Each result below shows which ingredient is responsible. Corn Silk Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Corn Silk with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Corn Silk Extract5 drug types · 290 drugs

Antidiabetes Drugs

Theoretically, taking corn silk with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research in diabetic mice shows that taking corn silk extract lowers fasting blood glucose levels.

Likelihood Possible Evidence D
Antihypertensive Drugs

Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Clinical research in both hypertensive and normotensive adults shows that taking corn silk extract lowers systolic and diastolic blood pressure.

Likelihood Possible Evidence D
Corticosteroids

Taking corn silk with corticosteroids might increase the risk of hypokalemia.
Clinical research shows that taking corn silk extract increases the urinary excretion of potassium.

Likelihood Possible Evidence D
Diuretic Drugs

Taking corn silk with diuretic drugs might increase the risk of adverse effects such as hyponatremia and hypokalemia.
Clinical research shows that taking corn silk extract increases urine volume and promotes the urinary excretion of sodium and potassium. Some patients may require electrolyte supplementation.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, suddenly stopping, starting, or changing corn silk treatment may alter the effects of warfarin.
Corn silk contains vitamin K. Individuals taking warfarin should consume a consistent daily amount of corn silk to maintain consistent anticoagulation.

Likelihood Likely Evidence D
Corn Silk Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Corn Silk, from the product label.

NusaPure

See all NusaPure products
Name
Gmax Central LLC
Street Address
4700 Millenia Boulevard, Suite 175 PMB 92909
City
Orlando
State
FL
ZipCode
32839
Pharmacist Counseling Corner

Corn Silk by NusaPure: Common Questions

Does Corn Silk by NusaPure interact with any medications?
Yes. Based on its ingredients, Corn Silk has a known interaction with 290 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Corn Silk contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant or breastfeeding?
Not during pregnancy — there isn't enough reliable safety data, so it's best avoided. While breastfeeding, safety is unknown. Talk with your doctor or pharmacist for personalized advice before using it in either situation.
Does corn silk actually work for blood pressure or diabetes?
The evidence in our data is insufficient to rate it. While animal and human studies hint that it may lower blood pressure and blood sugar, we don't have solid clinical evidence that it works as a supplement for these conditions.
Are there any side effects I should know about?
Adverse effects seem rare overall, but the most common ones reported with long-term oral use are low potassium and low sodium. Human safety data are limited, so we can't rule out other effects — and if you use it for a while, ask your pharmacist to monitor your electrolytes.
Why does corn silk interact with so many blood pressure and diabetes drugs?
Corn silk extract lowers blood pressure and blood sugar on its own, so when you combine it with medications that do the same thing, those effects can add up and become too strong. That's why timing and consistency matter.
What is corn silk, exactly?
Corn silk is the fine, thread-like strands you pull off an ear of corn. This product is an extract of those fibers, concentrated into a capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Corn Silk is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Corn Silk label
Go deeper

The Full Monographs Behind Corn Silk’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Corn Silk

Interacts with 290 drugs

Corn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence for these uses is limited, so it should...

Read the full Corn Silk monograph →
Sources

Sources & How We Checked

Corn Silk's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Corn Silk 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. George GO, Idu FK. Corn silk aqueous extracts and intraocular pressure of systemic and non-systemic hypertensive subjects. Clin Exp Optom. 2015 Mar;98(2):138-49. PubMed
  4. Sheng L, Chen Q, Di L, Li N. Evaluation of anti-diabetic potential of corn silk in high-fat diet/streptozotocin- induced type 2 diabetes mice model. Endocr Metab Immune Disord Drug Targets. 2020. PubMed

See these in context on the Corn Silk monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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