Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Cucumber Extract Ingredients & Drug Interactions

by BulkSupplements.com

Powder Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Cucumber Extract is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for hydration and skin care, cooling and soothing puffy eyes, mild diuretic effect.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cucumber Fruit Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Cucumber Extract by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is just one active ingredient: cucumber fruit extract. It's a concentrated form of cucumber, not the fresh vegetable you'd slice into a salad.

There are no inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Cucumber product and its label doesn't state a use — see Cucumber's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence doesn't support claims about what this extract does. The data shows insufficient reliable evidence to rate it for burns, diabetes, high cholesterol (hyperlipidemia), high blood pressure (hypertension), or osteoarthritis.

In plain terms: we don't have solid proof it works for any of these.

The evidence, ingredient by ingredient Cucumber

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cucumber is widely eaten as food and is generally well tolerated. When taken by mouth in supplement or extract form, it also appears to be well tolerated overall.

Topically (on skin), cucumber extract is well tolerated, though allergic reactions like eczema, redness, or irritation can happen in sensitive people. A rare serious reaction (anaphylaxis — sudden severe allergic reaction with trouble breathing, vomiting, and dizziness) has been reported, though it's uncommon.

Because this is a concentrated extract rather than whole cucumber, the safety of taking it during pregnancy or breastfeeding hasn't been studied. There isn't enough data to know either way.

Talk with your doctor or pharmacist for personalized advice if you're pregnant, planning pregnancy, or breastfeeding.

Side effects, ingredient by ingredient Cucumber

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cucumber.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (medications for type 2 diabetes or blood sugar control), this product may add to their effect and increase your risk of low blood sugar. Check with your doctor or pharmacist before combining them, and monitor your blood sugar closely if you do.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is one of the simplest supplements out there — just cucumber extract with no fillers. The main thing to watch is if you take diabetes medication: the extract may lower blood sugar further and increase the risk of hypoglycemia.

There's no solid evidence it works for the conditions it's sometimes marketed for. Before you start, check your exact medications with your doctor or pharmacist, especially if you have diabetes.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cucumber Extract, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X002KUD9LV
Net contents 100 Gram(s); 3.5 Ounce(s)
Market status On market
Date entered into DSLD Apr 23, 2024
DSLD ID 311461
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cucumber Extract by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 mg
Maximum serving Sizes:
500 mg
Servings per container
200
UPC/BARCODE
X002KUD9LV
IngredientAmount% DV
Cucumber Fruit Extract500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Bulk Supplements.com Clean & pure bulk supplements

Formulation

Free of: Added sugar, soy, dairy, yeast, gluten, additives

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 500 mg (about 1/5 tsp) once or twice daily, or as directed by a physician.

General Statements

Use an accurate milligram scale.

New

Storage

Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool place

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

See for yourself

Cucumber Extract by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Cucumber Extract by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 mg Dosage formPowder Servings per container200 Amounts shown are per serving.

Cucumber Fruit Extract

Interacts with
86 drugs
500 mg per serving

Cucumber is a common food vegetable that is mostly water and is generally safe to eat. As a supplement or skincare ingredient it is popular for hydrat...

Cucumber Fruit Extract monograph & interactions
Interaction report

Cucumber Extract by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Cucumber Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Cucumber Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cucumber Fruit Extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, cucumber seed might have additive effects with antidiabetes drugs and may increase the risk of hypoglycemia.
Animal research shows that cucumber seed extract can decrease blood glucose levels. Monitor blood glucose levels closely.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Cucumber Extract, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Cucumber Extract by BulkSupplements.com: Common Questions

Does Cucumber Extract by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Cucumber Extract has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cucumber Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does cucumber extract actually work for diabetes?
The data shows insufficient reliable evidence to rate it for diabetes. Animal research found that cucumber seed extract lowered blood glucose in the lab, but we don't have solid proof it works that way in people. Don't rely on it to manage your blood sugar.
Will this product lower my blood sugar if I take diabetes medication?
There's a theoretical risk it could add to the effect of your medication and increase your chance of low blood sugar. This is a Moderate-severity interaction. Monitor your blood sugar closely and talk with your doctor or pharmacist before you start, especially if you're already on diabetes medication.
Is it safe to take during pregnancy or breastfeeding?
The safety of concentrated cucumber extract during pregnancy or breastfeeding hasn't been studied. There isn't enough data to know either way. Talk with your doctor or pharmacist for personalized advice before you take it.
What are the side effects?
When taken by mouth, cucumber extract is generally well tolerated with no common side effects reported. A rare, serious allergic reaction (anaphylaxis) with trouble breathing and vomiting has been reported, but it's uncommon. Topically, some people may get redness, itching, or allergic eczema.
What's in this powder besides cucumber?
Just the cucumber fruit extract — there are no inactive fillers listed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cucumber Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cucumber Extract label
Sources

Sources & How We Checked

Cucumber Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cucumber 4 references
  1. Fiume MM, Bergfeld WF, Belsito DV, et al. Safety assessment of Cucumis sativus (cucumber)-derived ingredients as used in cosmetics. Int J Toxicol. 2014;33(2 suppl):47S-64S.
  2. Vlaicu PC, Rusu LC, Ledesma A, et al. Cucumber anaphylaxis in a latex-sensitized patient. J Investig Allergol Clin Immunol. 2011;21(3):236-9.
  3. Minaiyan M, Zolfaghari B, Kamal A. Effect of hydroalcoholic and buthanolic extract of Cucumis sativus seeds on blood glucose level of normal and streptozotocin-induced diabetic rats. Iran J Basic Med Sci. 2011;14(5):436-42.
  4. Zachariae CO. Cucumber contact dermatitis. Contact Dermatitis. 2000;43(4):240-1. DOI

See these in context on the Cucumber monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring