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Dietary supplement

Daily Digestive Enzymes Ingredients & Drug Interactions

by Probulin

Daily Digestive Enzymes label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Daily Digestive Enzymes against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Daily Digestive Enzymes is a dietary supplement by Probulin with 7 active ingredients.Based on those ingredients, 184 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Daily Digestive Enzymes by Probulin

Ask about any prescription or over-the-counter medication and we check it for interactions with Daily Digestive Enzymes by Probulin — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Daily Digestive Enzymes by Probulin

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 21 active ingredients.
  • “Hybrid-Zyme Blend” is a proprietary blend — the label gives one combined amount (400 mg) without saying how much of each component you get.
  • “Makzyme-Pro Enzyme Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Protein Digesting Enzyme Activity” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Probulin Daily Digestive Enzymes contains 21 active ingredients — a mix of digestive enzymes and probiotics designed to help break down food and support gut health. The enzyme blend includes amylase and glucoamylase (which break down carbohydrates), papain and proteases (which break down proteins), lipase (which breaks down fats), and several others including cellulase, lactase, and phytase.

It also includes two live probiotic strains: Lactobacillus acidophilus and Lactobacillus casei. The product is completed with inactive ingredients: complex marine polysaccharides, cellulose, and rice maltodextrin (binders and fillers).

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • The label markets general wellness (“Support digestion”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Lactose intolerance — rated "Effective" (Lactase) (Natural Medicines).
  • On file: Antibiotic-associated diarrhea — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Bacterial vaginosis — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Helicobacter pylori — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Irritable bowel syndrome (IBS) — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).

The evidence for these enzymes is mixed and mostly limited. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.

Lactase is effective for lactose intolerance — that one's well established. For the other enzymes in this blend — papain, proteases, lipase, and the rest — the evidence we have is insufficient to rate whether they work for any condition.

If you're taking this for a specific digestive issue, talk with your pharmacist or doctor about whether the evidence supports it for your situation.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of these ingredients are generally well tolerated when taken at typical doses. Papain may cause allergic reactions (itchy eyes, runny nose, abdominal cramps, diarrhea) in sensitive people, and high doses carry rare risks of severe stomach irritation or even esophageal perforation.

Proteases and lipase can cause mild digestive upset or allergic reactions in some individuals. Lactobacillus acidophilus is safe in healthy adults but rarely can cause gastrointestinal discomfort (bloating, gas, diarrhea) when combined with other probiotics.

For pregnancy: concentrated papain and unripe papaya products should be avoided — the safety data advises against them. Protease safety hasn't been established in pregnancy, so it's best avoided unless prescribed.

Lipase, lactase, and phytase have limited pregnancy data — check with your doctor first. For breastfeeding, there isn't enough reliable safety data on papain, protease, or phytase; lactase is likely safe but talk with your healthcare provider before regular use.

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 6 matched ingredients can interact with medications — Papain, Lactobacillus Acidophilus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 184 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting this product, check with your pharmacist if you take warfarin (a blood thinner) — papain may increase its effects. Also mention any antibiotic drugs; if you take them, you'll need to space out the dose of this supplement to protect the probiotic's effectiveness.

No interactions are documented for the other checked ingredients, but several enzymes in this formula we cannot evaluate because we hold no interaction data for them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product is for people looking for broad digestive enzyme and probiotic support. If you take warfarin or antibiotics, you'll need to check with your pharmacist first — these interact with ingredients in the formula.

Pregnant or breastfeeding individuals should discuss use with their doctor, as safety data are limited for several of the enzymes.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 21 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Daily Digestive Enzymes, straight from the product label.

Brand Probulin
Barcode (UPC) 855757003459
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 299940
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Halal, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Daily Digestive Enzymes by Probulin, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
855757003459
IngredientAmount% DV
Amylase0 NP--
Papain0 NP--
Protease0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Peptidase0 NP--
Invertase0 NP--
Lactobacillus acidophilus0 NP--
Lactobacillus plantarum0 NP--
Glucoamylase0 NP--
Xylanase0 NP--
Pectinase0 NP--
Maltase0 NP--
Beta-Glucanase0 NP--
Phytase0 NP--
Hemicellulase0 NP--
Lactobacillus casei0 NP--
Alpha-Galactosidase0 NP--
Aspergillus niger0 NP--
Aspergillus oryzae0 NP--
Hybrid-Zyme Blend400 mg--
Makzyme-Pro Enzyme Blend0 NP--
Protein Digesting Enzyme Activity0 NP--
Gluten Protein Digesting Enzyme Activity0 NP--
Carbohydrate Digesting Enzyme Activity0 NP--
Fiber Digesting Enzyme Activity0 NP--
Fat Digesting Enzyme Activity0 NP--
Dairy Digesting Enzyme Activity0 NP--

Other ingredients: Complex Marine Polysaccharides, Cellulose, Cellulose, Rice Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Probulin The Next Generation Of Probiotics

Formulation

Non-GMO

Support digestion MAKTrek Bypass delivery system

Formulated by Jason Mitchell, N.D. with prominent Gastroenterologist Dr. Shekhar Challa.

No GMOs No gluten No wheat No magnesium stearate No dairy No soy

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take one (1) capsule with a meal. More may be taken if necessary or as directed by a healthcare professional.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Do not accept if seal is broken.

Keep out of the reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Halal

Formula

Halal

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Daily Digestive Enzymes by Probulin label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Daily Digestive Enzymes label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Daily Digestive Enzymes by Probulin

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Hybrid-Zyme Blend

400 mg per serving
  • › Makzyme-Pro Enzyme Blend
  • › Protein Digesting Enzyme Activity
  • › Gluten Protein Digesting Enzyme Activity
  • › Carbohydrate Digesting Enzyme Activity
  • › Fiber Digesting Enzyme Activity
  • › Fat Digesting Enzyme Activity
  • › Dairy Digesting Enzyme Activity

Other (inactive) ingredients: Complex Marine Polysaccharides, Cellulose, Cellulose, Rice Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Daily Digestive Enzymes by Probulin Drug Interactions

Want to check YOUR meds against Daily Digestive Enzymes?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
184Drugs
184 Moderate

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Daily Digestive Enzymes interact with 184 drugs. Click any drug to see the details.

0 of the 7 ingredients in Daily Digestive Enzymes interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Daily Digestive Enzymes with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Daily Digestive Enzymes, from the product label.

Probulin

See all Probulin products
Name
Probulin
Street Address
3820 NW 14th Street, Suite A & B
City
Topeka
State
KS
ZipCode
66618
Phone Number
1-888-697-8770
Web Address
www.probulin.com
Pharmacist Counseling Corner

Daily Digestive Enzymes by Probulin: Common Questions

Does Daily Digestive Enzymes by Probulin interact with any medications?
Yes. Based on its ingredients, Daily Digestive Enzymes has a known interaction with 184 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Daily Digestive Enzymes contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this help with bloating and gas?
The product contains enzymes meant to break down food and probiotics (Lactobacillus acidophilus) that are possibly effective for irritable bowel syndrome, which sometimes involves bloating. However, the evidence for most of these specific enzymes isn't established in our data. Some people do report mild gas or bloating when they first start probiotics, though that usually settles. Talk with your pharmacist about whether this formula matches what you're trying to manage.
Is this safe if I'm pregnant?
Not fully established. Papain in pregnancy is a concern, so it's best avoided while pregnant. Protease safety hasn't been confirmed in pregnancy either. Lipase and phytase have very limited data. Please talk with your doctor or pharmacist before taking this while pregnant so they can weigh the ingredients against your individual situation.
Can I take this with antibiotics?
Not at the same time. This product contains Lactobacillus acidophilus, a live probiotic that antibiotics can kill, making the probiotic less effective. Ask your pharmacist how long to wait between doses — usually it's at least a couple of hours, but it depends on the antibiotic.
What does papain do in here?
Papain is an enzyme from papaya that's meant to help break down proteins in food. The evidence for it in supplements isn't strong enough to rate, though it's been used traditionally in digestive products. If you're on warfarin, this ingredient is something we need to flag for you.
Does this have any fillers?
Yes — the inactive ingredients are complex marine polysaccharides, cellulose, and rice maltodextrin. These are binders and flow agents that help the capsule hold together, not active ingredients. If you have allergies or sensitivities to any of these, let us know.
Is lactase in here for lactose intolerance?
Yes, lactase is in this blend and it's effective for lactose intolerance. That said, if lactose intolerance is your main concern, a standalone lactase product might be more straightforward. This is a broader digestive enzyme formula.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Daily Digestive Enzymes is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Daily Digestive Enzymes label
Sources

Sources & How We Checked

Daily Digestive Enzymes's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 38 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Papain 11 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Saf 1997;17:342-56.
  3. Shuttleworth D, Hill S, Marks R, Connelly DM. Relief of experimentally induced pruritus with a novel eutectic mixture of local anaesthetic agents. Br J Dermatol 1988;119:535-40.
  4. Mansfield LE, Ting S, Haverly RW, Yoo TJ. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge. Ann Allergy 1985;55:541-3.
  5. Martin, T., Uhder, K., Kurek, R., Roeddiger, S., Schneider, L., Vogt, H. G., Heyd, R., and Zamboglou, N. Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial PubMed
  6. Walker-Renard, P. Update on the medicinal management of phytobezoars. Am J Gastroenterol. 1993;88(10):1663-1666.
  7. Tymoszuk D, Wiszniewska M, Walusiak-Skorupa J. Papain-induced occupational rhinoconjunctivitis and asthma - A case report. Med Pr 2016;67(1):109-12. PubMed
  8. Soto-Mera MT, López-Rico MR, Filgueira JF, et al. Occupational allergy to papain. Allergy 2000;55(10):983-4. PubMed
  9. Tarlo SM, Shaikh W, Bell B, et al. Papain-induced allergic reactions. Clin Allergy 1978;8(3):207-15. PubMed
  10. Baur X, König G, Bencze K, Fruhmann G. Clinical symptoms and results of skin test, RAST and bronchial provocation test in thirty-three papain workers: Evidence for strong immunogenic potency and clinically relevant proteolytic e?ects of airborne papain. C
  11. Novey HS, Keenan WJ, Fairshter RD, Wells ID, Wilson AF, Culver BD. Pulmonary disease in workers exposed to papain: clinico-physiological and immunological studies. Clin Allergy 1980;10(6):721-31. PubMed

See these in context on the Papain monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Phytase 7 references
  1. Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
  2. Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
  3. van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
  4. Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
  5. Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
  6. Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
  7. Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.

See these in context on the Phytase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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