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Dietary supplement

Damiana Extract 750 mg Ingredients & Drug Interactions

by SuperSmart

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Damiana Extract 750 mg is a dietary supplement by SuperSmart with 1 active ingredient. Its ingredients are commonly taken for low libido / aphrodisiac, anxiety and stress, mood and mild low energy.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Damiana leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Damiana Extract 750 mg by SuperSmart

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: damiana leaf extract at 750 mg per capsule. Damiana is a plant native to Central and South America, traditionally used in herbal medicine.

The capsule itself also contains hypromellose, acacia gum, and white rice flour as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Damiana product and its label doesn't state a use — see Damiana's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold on damiana for sexual dysfunction, asthma, headache, cognitive function, constipation, and depression all falls into insufficient reliable evidence — meaning the data aren't solid enough yet to draw conclusions. If you're considering this for one of those uses, talk with your pharmacist or doctor about what the current evidence can and can't tell you.

The evidence, ingredient by ingredient Damiana

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Damiana is likely fine in the food or tea amounts most adults consume, but human safety data are limited overall. At very high doses — the facts note that 200 grams of damiana extract has caused severe neurological effects like tetanus-like convulsions — it carries real risks.

Safety data during pregnancy and breastfeeding aren't established enough, so the advice is to avoid it during both. If you're pregnant, planning pregnancy, or breastfeeding, don't start this product without talking to your doctor or pharmacist first.

Side effects, ingredient by ingredient Damiana

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Damiana.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your exact antidiabetes medications (like metformin, sulfonylureas, or insulin) before taking this product — the risk of low blood sugar (hypoglycemia) is Moderate. No other interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Damiana extract might interest someone drawn to traditional herbal use, but the evidence for most health claims isn't solid yet. If you take diabetes medications, you need to check with us before starting — there's a real risk of blood sugar dropping too low.

Pregnant or breastfeeding? Skip it.

Otherwise, run your medications through our interaction checker.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Damiana Extract 750 mg, straight from the product label.

Brand SuperSmart
Barcode (UPC) 5453003827825
Net contents 90 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jun 25, 2025
DSLD ID 332672
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Damiana Extract 750 mg by SuperSmart, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
5453003827825
IngredientAmount% DV
Damiana leaf extract750 mg--

Other ingredients: Hypromellose, Acacia Gum, White Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formula

Damiana Extract 750 mg per day Each capsule contains 250 mg of damiana leaf extract.

Formulation

Guarantees: Vegan, Non-GMO, gluten free, soy free, dairy free. No coloring, preservatives, or flavorings.

Guarantees: Vegan, Non-GMO, gluten free, soy free, dairy free.

FDA Registered Lab, Good Manufacturing Practice, Made in USA.

Suggested/Recommended/Usage/Directions

Directions: Adults. As a supplement, take 3 capsules daily or as directed by the practitioner.

Precautions

Cautions: Keep out of reach of children.

Consult a healthcare provider before using this product if pregnant, breastfeeding, or having health concerns.

Tamper evident: Do not use if seal under cap is broken or missing.

Storage

Store in a cool, dry place.

See for yourself

Damiana Extract 750 mg by SuperSmart label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Damiana Extract 750 mg by SuperSmart

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Damiana leaf extract

Interacts with
86 drugs
750 mg per serving

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is...

Damiana leaf extract monograph & interactions

Other (inactive) ingredients: Hypromellose, Acacia Gum, White Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Damiana Extract 750 mg by SuperSmart Drug Interactions

Want to check YOUR meds against Damiana Extract 750 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Damiana Extract 750 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Damiana leaf extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that taking damiana lowers blood glucose level.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Damiana Extract 750 mg, from the product label.

SuperSmart

See all SuperSmart products
Name
SuperSmart USA LLC
City
Miami
State
FL
ZipCode
33130
Phone Number
1 (786) 522-3907
Web Address
us.SuperSmart.com
Pharmacist Counseling Corner

Damiana Extract 750 mg by SuperSmart: Common Questions

Does Damiana Extract 750 mg by SuperSmart interact with any medications?
Yes. Based on its ingredients, Damiana Extract 750 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Damiana Extract 750 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No — safety data aren't available for either pregnancy or breastfeeding, so the advice is to avoid it. Talk with your doctor or pharmacist about what's safe for you right now.
Does damiana actually work for sexual dysfunction?
The evidence we hold isn't strong enough to say. We've rated it insufficient reliable evidence, which means more research is needed before we can draw solid conclusions.
What are the side effects?
At normal food and tea amounts, damiana is generally well tolerated, though human safety data are limited. At very high doses — 200 grams of extract — it's been shown to cause severe neurological symptoms like convulsions. The 750 mg in this capsule is much lower, but we don't have broad safety data for this dose range.
Why does this interact with diabetes medications?
Animal research shows damiana lowers blood glucose level. If you're already taking a drug to lower your blood sugar, adding damiana could push it too low. That's why you need to check with your pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Damiana Extract 750 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Damiana Extract 750 mg label
Go deeper

The Full Monographs Behind Damiana Extract 750 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Damiana Extract 750 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Damiana 2 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Alarcon-Aquilar FJ, Roman-Ramos R, Perez-Gutierrez S, et al. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10. PubMed

See these in context on the Damiana monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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