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Dietary supplement

Damiana Leaves 600 mg Ingredients & Drug Interactions

by Nature's Way

Damiana Leaves 600 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Damiana Leaves 600 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Damiana Leaves 600 mg is a dietary supplement by Nature's Way with 1 active ingredient. Its ingredients are commonly taken for low libido / aphrodisiac, anxiety and stress, mood and mild low energy.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Damiana. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Damiana Leaves 600 mg by Nature's Way

Ask about any prescription or over-the-counter medication and we check it for interactions with Damiana Leaves 600 mg by Nature's Way — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Damiana Leaves 600 mg by Nature's Way

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: damiana leaf at 600 mg per capsule. The capsules also hold two inactive ingredients — hypromellose and silica — which are used as a capsule shell and anti-caking agent.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Damiana's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: traditional libido support.
  • We looked for evidence on: Erectile dysfunction (ED), Sexual dysfunction, Low libido, Sexual desire.
  • The closest evidence on file: Damiana is rated "Insufficient Reliable Evidence To Rate" for Sexual dysfunction (Natural Medicines).
  • Also on file: Damiana is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED).

The evidence for damiana isn't established. Our data shows insufficient reliable evidence to rate it for sexual dysfunction, asthma, headache, cognitive function, constipation, or depression.

That doesn't mean it doesn't work — it means the research we hold isn't solid enough to make a call either way.

The evidence, ingredient by ingredient Damiana

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Damiana is likely fine in the amounts you'd get from food or tea for most adults, but human safety data are limited. At very high doses — researchers tested 200 grams of damiana extract — it caused serious muscle spasms and convulsion-like symptoms.

Because safety data in pregnancy and breastfeeding are not adequate, the data advises against use during pregnancy and while breastfeeding.

Side effects, ingredient by ingredient Damiana

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Damiana.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your diabetes medications before taking this product — damiana may lower blood sugar and raise the risk of hypoglycemia when combined with antidiabetes drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Damiana is a single-ingredient product for people curious about traditional uses, though the evidence for its benefits isn't solid yet. If you take diabetes medication, you'll want to check with your pharmacist before starting it.

Talk to your pharmacist if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Damiana Leaves 600 mg, straight from the product label.

Brand Nature's Way
Barcode (UPC) 033674122006
Net contents 100 Vegan Capsule(s)
Market status On market
Date entered into DSLD Apr 24, 2025
DSLD ID 327945
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Damiana Leaves 600 mg by Nature's Way, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
50
UPC/BARCODE
033674122006
IngredientAmount% DV
Damiana600 mg--

Other ingredients: Hypromellose, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Traditional libido support Made with the quality you trust

Vegan Gelatin free

Vegan Gelatin free

Bottled and tested in the USA

Plant powered

Non GMO Project Verified nongmoproject.org

Gluten free. No salt, wheat, corn, soy, dairy, gelatin, or artificial colors, flavors, or preservatives.

Formula

600 mg damiana (leaf) per 2-capsule serving

Damiana Leaves 600 mg per 2-capsule serving

General Statements

Botanicals are sourced where they grow best Explore more products at naturesway.com Bottle made from 50% post-consumer recycled plastic

Questions? 1-800-962-8873 / naturesway.com

Seals/Symbols

Vegan Gelatin free

Non GMO Project Verified nongmoproject.org

Brand IP Statement(s)

Copyright 2024 Nature's Way Brands, LLC

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Recommendation: Adults take 2 capsules three times daily.

Precautions

If you are pregnant, nursing, or taking any medications, consult a healthcare professional before use.

Keep out of reach of children.

Safety sealed with inner seal. Do not use if seal is broken or missing.

Storage

Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Damiana Leaves 600 mg by Nature's Way label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Damiana Leaves 600 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Damiana Leaves 600 mg by Nature's Way

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Damiana

Interacts with
86 drugs
600 mg per serving

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is...

Damiana monograph & interactions

Other (inactive) ingredients: Hypromellose, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Damiana Leaves 600 mg by Nature's Way Drug Interactions

Want to check YOUR meds against Damiana Leaves 600 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Damiana 86

Individual Drug Interactions

The ingredients in Damiana Leaves 600 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Damiana Leaves 600 mg interact with drugs. Each result below shows which ingredient is responsible. Damiana

Each ingredient & the kinds of drugs it affects

For each ingredient in Damiana Leaves 600 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Damiana1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that taking damiana lowers blood glucose level.

Likelihood Possible Evidence D
Damiana full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Damiana Leaves 600 mg, from the product label.

Nature's Way

See all Nature's Way products
Name
Nature's Way Brands, LLC
City
Green Bay
State
WI
ZipCode
54311
Phone Number
1-800-962-8873
Web Address
naturesway.com
Pharmacist Counseling Corner

Damiana Leaves 600 mg by Nature's Way: Common Questions

Does Damiana Leaves 600 mg by Nature's Way interact with any medications?
Yes. Based on its ingredients, Damiana Leaves 600 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Damiana Leaves 600 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is damiana safe to take if I'm pregnant or breastfeeding?
No. The safety data advises against it during pregnancy and while breastfeeding because there isn't enough information to know it's safe. Talk with your doctor or pharmacist for personalized advice.
What is damiana used for?
Traditionally damiana has been used for sexual dysfunction, asthma, headache, cognitive function, constipation, and depression. However, our data shows insufficient reliable evidence to confirm it works for any of these.
Does damiana have any serious side effects?
At typical supplement doses, serious side effects are rare. But very high doses — 200 grams of damiana extract — have caused severe muscle spasms and convulsion-like symptoms in research. Stick to the labeled dose.
How much damiana is in each capsule?
Each capsule contains 600 mg of damiana leaf.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Damiana Leaves 600 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Damiana Leaves 600 mg label
Go deeper

The Full Monographs Behind Damiana Leaves 600 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Damiana

Interacts with 86 drugs

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is generally well tolerated in the small am...

Read the full Damiana monograph →
Sources

Sources & How We Checked

Damiana Leaves 600 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Damiana 2 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Alarcon-Aquilar FJ, Roman-Ramos R, Perez-Gutierrez S, et al. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10. PubMed

See these in context on the Damiana monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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