Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Detox Support Ingredients & Drug Interactions

by TerraVita

Detox Support label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Detox Support against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Detox Support is a dietary supplement by TerraVita with 3 active ingredients. Its ingredients are commonly taken for colds and flu, fever, body aches.Based on those ingredients, 87 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Boneset Glycerite Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Detox Support by TerraVita

Ask about any prescription or over-the-counter medication and we check it for interactions with Detox Support by TerraVita — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Detox Support by TerraVita

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (0.13 mL) without saying how much of each component you get.

TerraVita Detox Support is a liquid blend of 3 active ingredients. Boneset glycerite liquid extract and black walnut glycerite liquid extract are the two named botanicals; the product also lists a proprietary blend, which means some components aren't named on the label.

The inactive ingredient is glycerin, which is the liquid carrier. The exact amounts of each ingredient aren't shown because they're part of a proprietary blend, so we can't tell you how much of each plant you're getting per dose.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence doesn't establish whether this product works for any condition. Boneset and black walnut both carry insufficient reliable evidence to rate their effectiveness—meaning either the studies don't exist, aren't strong enough, or show conflicting results—for the conditions they're traditionally used for (common cold for boneset, coronary heart disease and wound healing for black walnut).

We have no effectiveness data for walnut leaf.

The evidence, ingredient by ingredient Boneset Black Walnut

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Boneset carries a caution: limited safety data and possible liver-toxic alkaloids mean careful, short-term use only if you choose to use it at all. Boneset is associated with nausea, severe diarrhea, and vomiting.

There's also a theoretical risk of liver damage at high doses, though boneset's alkaloids haven't been fully characterized for toxicity. Black walnut (the fruit itself) is generally well tolerated, but the leaf, bark, and hull—all present in this product—contain high tannins that may cause stomach upset.

Black walnut can also trigger tree-nut allergies and, with long-term use of related species, has been linked to tongue cancer risk. Don't use this product during pregnancy or breastfeeding.

Boneset is possibly unsafe in both; the safety data advises against it. Black walnut's safety during pregnancy and breastfeeding isn't established enough—the data advises against it while nursing, and there isn't enough information to know either way during pregnancy.

Side effects, ingredient by ingredient Boneset Black Walnut

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Boneset.
  • The most serious interaction on file is rated Moderate.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any seizure medications or other drugs that induce CYP3A4 (like carbamazepine), check with your pharmacist before using this product—boneset may increase toxic alkaloid formation. Altogether, these interactions span 85 individual medications; use the checker below to review your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product contains ingredients with incomplete safety evidence and potential liver toxicity concerns. If you're taking a seizure medication or other CYP3A4 inducer, check with us before starting.

Pregnant or nursing? Skip it.

Consider talking to your pharmacist about whether a short-term trial fits your situation and whether safer alternatives exist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Detox Support, straight from the product label.

Brand TerraVita
Barcode (UPC) 064435237813
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 282101
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Detox Support by TerraVita, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
25 Drop(s)
Maximum serving Sizes:
40 Drop(s)
Servings per container
227
UPC/BARCODE
064435237813
IngredientAmount% DV
Proprietary Blend0.13 mL--
Boneset Glycerite Liquid Extract0 NP--
Black Walnut Glycerite Liquid Extract0 NP--
Walnut Leaf Glycerite Liquid Extract0 NP--

Other ingredients: Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Copyright 2018 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Formula

Glycerite liquid extract (1:5)

Formulation

Alcohol free

Suggested/Recommended/Usage/Directions

Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.

Precautions

Keep away from children.

Do not use if safety seal around cap is broken or missing.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Detox Support by TerraVita label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Detox Support label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Detox Support by TerraVita

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

0.13 mL per serving

Other (inactive) ingredients: Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Detox Support by TerraVita Drug Interactions

Want to check YOUR meds against Detox Support?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
87Drugs
87 Moderate

Ingredients driving the most interactions

Boneset Glycerite Liquid Extract 87

Individual Drug Interactions

The ingredients in Detox Support interact with 87 drugs. Click any drug to see the details.

1 of the 3 ingredients in Detox Support interact with drugs. Each result below shows which ingredient is responsible. Boneset Glycerite Liquid Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Detox Support with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Boneset Glycerite Liquid Extract1 drug type · 87 drugs

Cytochrome P450 3A4 (Cyp3A4) Inducers

Boneset belongs to the genus Eupatorium, and many species of this genus contain hepatotoxic pyrrolizidine alkaloids (PAs). Hepatotoxic PAs are substrates of cytochrome P450 3A4 (CYP3A4). Theoretically, drugs that induce CYP3A4 might increase the conversion of PAs to toxic metabolites. Some drugs that induce CYP3A4 include carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), rifampin, rifabutin (Mycobutin), and others.

Likelihood Possible Evidence D
Boneset Glycerite Liquid Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Detox Support, from the product label.

TerraVita

See all TerraVita products
Name
ZooScape LLC
Phone Number
844-449-0444
Web Address
www.ZooScape.com
Pharmacist Counseling Corner

Detox Support by TerraVita: Common Questions

Does Detox Support by TerraVita interact with any medications?
Yes. Based on its ingredients, Detox Support has a known interaction with 87 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Detox Support contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
No. Boneset is possibly unsafe during both pregnancy and breastfeeding because of potential toxicity and lack of safety data; harmful alkaloids may pass to your infant. Black walnut's safety in pregnancy isn't well enough established to know either way, but the data advise against it while breastfeeding. Talk to your doctor before considering this product in either situation.
What side effects might I experience?
Boneset commonly causes nausea, severe diarrhea, and vomiting. At high doses, liver damage is possible. Black walnut (the leaf, bark, and hull in this product) may cause stomach upset due to its tannin content. If you're allergic to tree nuts, black walnut can trigger a serious allergic reaction.
Does this product actually work for detoxification or colds?
The evidence isn't established. Boneset is traditionally used for colds, but we don't have reliable studies showing it works. Black walnut is studied for heart disease and wound healing, but again, the evidence is insufficient to rate it. We have no effectiveness data for walnut leaf.
Why does the label show a 'proprietary blend' instead of ingredient amounts?
Companies use proprietary blends to keep their formula secret from competitors. The downside for you is that you can't see exactly how much of each ingredient you're getting in each dose, so we can't predict how strong the effect or side effects might be.
Is black walnut safe to take long-term?
The safety data for black walnut are limited, and long-term use hasn't been well studied. Additionally, daily use of related walnut species has been linked to increased tongue cancer risk. Use it short-term if at all, and talk to your pharmacist about duration.
I'm on a seizure medication—can I take this?
Check with your pharmacist first. Boneset in this product interacts with seizure drugs like carbamazepine in a way that could increase the toxic breakdown of plant alkaloids boneset contains. Your pharmacist can review your exact medication and give you personalized advice.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Detox Support label
Go deeper

The Full Monographs Behind Detox Support’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Boneset

Interacts with 87 drugs

Boneset is a traditional North American herb long used in teas for fevers, colds, and flu, but modern human studies are very limited. It contains compounds (pyrrolizidine alkaloids) that may...

Read the full Boneset monograph → Herb & supplement monograph

Black Walnut

Black walnut is a tree whose green hulls are traditionally used as a natural antiparasitic and digestive remedy, but solid human evidence for these uses is lacking. It contains a compound ca...

Read the full Black Walnut monograph →
Sources

Sources & How We Checked

Detox Support's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Boneset 5 references
  1. Chojkier M. Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids. J Hepatol 2003;39:437-46. PubMed
  2. Roeder E. Medicinal plants in Europe containing pyrrolizidine alkaloids. Pharmazie 1995;50:83-98.
  3. Wang YP, Yan J, Fu PP, Chou MW. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. Toxicol Lett 2005;155:411-20. PubMed
  4. Gassinger, C. A., Wunstel, G., and Netter, P. [A controlled clinical trial for testing the efficacy of the homeopathic drug eupatorium perfoliatum D2 inthe treatment of common cold (author's transl)]. Arzneimittelforschung. 1981;31(4):732-736.
  5. Colegate SM, Upton R, Gardner DR, Panter KE, Betz JM. Potentially toxic pyrrolizidine alkaloids in Eupatorium perfoliatum and three related species. Implications for herbal use as boneset. Phytochem Anal. 2018;29(6):613-626.

See these in context on the Boneset monograph →

Black Walnut 3 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor

See these in context on the Black Walnut monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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