DHEA Ultra 100 mg Ingredients & Drug Interactions
by ForestLeaf
What is this page for?
First and foremost: checking DHEA Ultra 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
DHEA Ultra 100 mg is a dietary supplement by ForestLeaf with 1 active ingredient. Its ingredients are commonly taken for anti-aging and low dhea levels, mood and depression, vaginal dryness and sexual health.Based on those ingredients, 776 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dehydroepiandrosterone. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against DHEA Ultra 100 mg by ForestLeaf
Ask about any prescription or over-the-counter medication and we check it for interactions with DHEA Ultra 100 mg by ForestLeaf — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of DHEA Ultra 100 mg by ForestLeaf
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
DHEA Ultra contains one active ingredient: dehydroepiandrosterone (DHEA), a hormone your body naturally makes. At 100 mg per capsule, this is a moderate dose.
The capsule also contains inactive ingredients (hypromellose, microcrystalline cellulose, magnesium stearate, and silicon dioxide) that help hold it together and allow it to dissolve in your digestive tract.
Does it work?
Strong evidence
The evidence for DHEA varies by use. It's rated likely effective for vaginal atrophy (thinning and dryness of vaginal tissue).
For infertility and aging skin, the evidence is less robust—rated possibly effective, meaning some research supports it but more data would help. It's also rated possibly effective for depression, though again the evidence is mixed.
If you're considering DHEA for any of these purposes, talk with your doctor about whether the research supports it for your specific situation.
How safe is it?
Well-documented data
DHEA is generally well tolerated at typical doses for short-term use, but there's a potential long-term concern: some research hints that prolonged oral DHEA use might increase cancer risk, so extended use warrants medical supervision. The most common side effects are acne (especially in women and usually mild), headache, insomnia, mood changes, and nausea.
Women may also experience masculinization effects—voice deepening, facial hair growth, irregular periods, or oily skin. Men may notice aggression or breast changes.
DHEA is not safe in pregnancy and should be avoided while breastfeeding due to insufficient safety data. Because DHEA is a hormone, it should only be used under medical guidance.
Meds to double-check
Moderate interaction found
Before you take DHEA Ultra, double-check with your pharmacist or doctor if you use antidepressants (especially SSRIs), blood thinners or antiplatelet drugs, triazolam (a sleep medication), aromatase inhibitors or other cancer drugs like tamoxifen or fulvestrant, or any drugs metabolized by the CYP3A4 enzyme (your pharmacist can help identify these). Also, if you're due for a tuberculosis vaccine, let your doctor know you're taking DHEA.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
DHEA Ultra is most appropriate for people addressing specific hormonal issues like vaginal atrophy, ideally under a doctor's care. If you take antidepressants, blood thinners, sleep aids, cancer medications, or other drugs your liver processes, check with your pharmacist before starting—the interactions are real and worth reviewing with your exact medication list.
Because DHEA is a hormone that can cause side effects and interact with medications, medical supervision is important.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about DHEA Ultra 100 mg, straight from the product label.
| Brand | ForestLeaf |
|---|---|
| Net contents | 90 Vegetable Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2025 |
| DSLD ID | 323036 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for DHEA Ultra 100 mg by ForestLeaf, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Dehydroepiandrosterone | 100 mg | -- |
Other ingredients: Hypromellose, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
DHEA Ultra supports the male and female hormone from declining with age, playing a vital role in energy, mood, and lean muscle.
DHEA, known as the "Fountain of Youth Vitamin" promotes vitality.
Formulation
Hormonal Balance Energy & Mood Muscle Mass Cognitive Function GMP Complaint Lab Verified
Non GMO Dairy, gluten, egg & nut free
Vegetarian friendly
Supports optimal hormone levels Mood & vitality boost Tested for absorption
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
Made in USA with globally sourced ingredients Vegetarian friendly
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, adults take 1 capsule daily, with a meal, or as directed by your healthcare professional.
Precautions
Caution: Keep out of reach of children.
If you are pregnant, nursing, or taking any prescription medicine, consult your physician before taking this product.
Storage
Store in a cool, dry place.
General Statements
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Is this label outdated? Report a formula or label change and our pharmacy team will review it.
DHEA Ultra 100 mg by ForestLeaf label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in DHEA Ultra 100 mg by ForestLeaf
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Dehydroepiandrosterone
Interacts with776 drugs
DHEA is a natural hormone that the body makes and that declines with age, and it is sold as a supplement claiming many benefits. The evidence is mixed...
Dehydroepiandrosterone monograph & interactionsOther (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
DHEA Ultra 100 mg by ForestLeaf Drug Interactions
HelloPharmacist Interaction Report
DHEA Ultra by ForestLeaf is a single-ingredient supplement that does interact with several medication types.
The most serious concern is with antidepressants (especially SSRIs like sertraline or fluoxetine): DHEA may increase the risk of psychiatric side effects, and there's a documented case report of a manic episode when DHEA was combined with an SSRI. This risk may be higher in younger people.
Read the full breakdown — every affected drug type, severity by severity
DHEA also interacts moderately with blood thinners (anticoagulants and antiplatelet drugs like warfarin or aspirin) — it may boost bleeding risk. If you take triazolam (Halcion, a sleep aid), DHEA can raise its blood levels and increase drowsiness or side effects.
DHEA is a potent estrogen-like compound, so it may interfere with several cancer medications: aromatase inhibitors, tamoxifen, and fulvestrant. It can also theoretically raise levels of other drugs that your liver metabolizes via the CYP3A4 pathway, though the clinical importance isn't fully clear yet.
Additionally, DHEA might reduce how well the tuberculosis vaccine works.
Additionally, some drugs metabolized by CYP3A4 (a liver enzyme) may see higher blood levels when combined with DHEA, but we don't yet know how much that matters in practice.
Additionally, we've checked the one active ingredient in this product against our data. Please run your exact medications through the interaction checker on this page to see if any of them are affected.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against DHEA Ultra 100 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in DHEA Ultra 100 mg interact with 776 drugs. Click any drug to see the details.
1 of the 1 ingredient in DHEA Ultra 100 mg interact with drugs. Each result below shows which ingredient is responsible. Dehydroepiandrosterone
AvanafilStendra
How Avanafil interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Avanafil interactionAvapritinibAyvakit
How Avapritinib interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Avapritinib interactionAxitinibInlyta
How Axitinib interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Axitinib interactionAzelastine Hydrochloride, Fluticasone PropionateDymista
How Azelastine Hydrochloride, Fluticasone Propionate interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Azelastine Hydrochloride, Fluticasone Propionate interactionBacille Calmette-guerinBCG
How Bacille Calmette-guerin interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneTuberculosis Vaccine Moderate
Interaction Summary
DHEA might reduce the effectiveness of the tuberculosis vaccine.
Read the full Dehydroepiandrosterone + Bacille Calmette-guerin interactionBazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the effects and adverse effects of estrogen therapy.
Read the full Dehydroepiandrosterone + Bazedoxifene Acetate, Conjugated Estrogens interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Beclomethasone Dipropionate interactionBedaquilineSirturo
How Bedaquiline interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Bedaquiline interactionBelladonna Alkaloids, Chlorpheniramine, Phenylephrine, PhenylpropanolamineRespa ARM
How Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interactionBelladonna Alkaloids, Ergotamine Tartrate, PhenobarbitalBel Tabs, Bellamine-S, Bellaphen-S, Duragal S, Phenarbal S, Spastrin
How Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interactionBelladonna, Caffeine, Ergotamine, PentobarbitalMicomp PB
How Belladonna, Caffeine, Ergotamine, Pentobarbital interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Belladonna, Caffeine, Ergotamine, Pentobarbital interactionBelladonna, Ergotamine Tartrate, Phenobarbital
How Belladonna, Ergotamine Tartrate, Phenobarbital interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Belladonna, Ergotamine Tartrate, Phenobarbital interactionBelladonna, Ergotamine, PhenobarbitalBellergal-S
How Belladonna, Ergotamine, Phenobarbital interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Belladonna, Ergotamine, Phenobarbital interactionBellafoline, Caffeine, Ergotamine Tartrate, PentobarbitalCafergot PB
How Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interactionBelumosudil MesylateRezurock
How Belumosudil Mesylate interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Belumosudil Mesylate interactionBenzhydrocodone, AcetaminophenApadaz
How Benzhydrocodone, Acetaminophen interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Benzhydrocodone, Acetaminophen interactionBepridilVascor
How Bepridil interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Bepridil interactionBetrixabanBevyxxa
How Betrixaban interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHEA might increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Dehydroepiandrosterone + Betrixaban interactionBexaroteneTargretin
How Bexarotene interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Bexarotene interactionBictegravir, Emtricitabine, Tenofovir AlafenamideBiktarvy
How Bictegravir, Emtricitabine, Tenofovir Alafenamide interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Bictegravir, Emtricitabine, Tenofovir Alafenamide interactionBivalirudinAngiomax, Angiomax Rtu, Angiox
How Bivalirudin interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHEA might increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Dehydroepiandrosterone + Bivalirudin interactionBoceprevirVictrelis
How Boceprevir interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Boceprevir interactionBosentanTracleer
How Bosentan interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Bosentan interactionBosutinibBosulif
How Bosutinib interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Bosutinib interactionBrentuximab VedotinAdcetris
How Brentuximab Vedotin interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Brentuximab Vedotin interactionBrexanoloneZulresso
How Brexanolone interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneAntidepressant Drugs Moderate
Interaction Summary
Theoretically, DHEA might increase the risk of psychiatric adverse events when used with antidepressants.
Read the full Dehydroepiandrosterone + Brexanolone interactionBrexpiprazoleRexulti
How Brexpiprazole interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Brexpiprazole interactionBrigatinibAlunbrig
How Brigatinib interacts with DHEA Ultra 100 mg — through 1 ingredient. Tap an ingredient for the detail:
DehydroepiandrosteroneCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Dehydroepiandrosterone + Brigatinib interactionEach ingredient & the kinds of drugs it affects
For each ingredient in DHEA Ultra 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Dehydroepiandrosterone
Anticoagulant/Antiplatelet Drugs
Theoretically, DHEA might increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Human and laboratory research show that DHEA and DHEA-S can inhibit platelet aggregation.
Antidepressant Drugs
Theoretically, DHEA might increase the risk of psychiatric adverse events when used with antidepressants.
In a human case report, the use of a selective serotonin reuptake inhibitor (SSRI) with DHEA caused a manic episode. Concern for this interaction may be greater in younger individuals with higher baseline DHEA levels.
Aromatase Inhibitors
Theoretically, DHEA might interfere with the clinical effects of aromatase inhibitors.
DHEA is a potent estrogen agonist, which may antagonize the anti-estrogen activity of aromatase inhibitors.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Some preliminary evidence shows that DHEA may inhibit CYP3A4; however, the clinical significance of this potential interaction is not known.
Fulvestrant (Faslodex)
Theoretically, DHEA might interfere with the anti-estrogen effects of fulvestrant.
DHEA is a potent estrogen agonist. Some research shows that it can overcome the estrogen receptor antagonist action of fulvestrant in estrogen-receptor positive cancer cells.
Tamoxifen (Nolvadex)
Theoretically, DHEA might interfere with the anti-estrogen effects of tamoxifen.
DHEA is a potent estrogen agonist. Some research shows that it can overcome the estrogen receptor antagonist activity of tamoxifen in estrogen-receptor positive cancer cells.
Triazolam (Halcion)
DHEA can increase blood levels of triazolam.
Administration of DHEA 200 mg daily for two weeks was shown to inhibit the cytochrome P450 3A4 (CYP3A4) metabolism of triazolam. This inhibition appears to be due to DHEA-S, rather than DHEA.
Tuberculosis Vaccine
DHEA might reduce the effectiveness of the tuberculosis vaccine.
Animal research shows that high doses of DHEA can reduce the efficacy of the Bacillus Calmette-Guérin (BCG) tuberculosis vaccine.
Estrogens
Theoretically, DHEA might increase the effects and adverse effects of estrogen therapy.
DHEA is a precursor to estrogen and androgen and is metabolized into those substances. In clinical research, DHEA supplements increase the levels of these hormones. Also, in clinical research, estrogen-progestin oral contraceptives and conjugated estrogens reduce blood levels of DHEA and DHEA-S. The clinical significance of these findings is unclear.
Testosterone
Theoretically, DHEA might increase the effects and side effects of testosterone therapy.
DHEA is a precursor to estrogen and androgen and is metabolized into those substances. In clinical research, DHEA supplements increase the levels of these hormones. The clinical significance of these findings is unclear.
Brand information
Manufacturer and brand details for DHEA Ultra 100 mg, from the product label.
ForestLeaf
See all ForestLeaf products- Name
- ForestLeaf
- City
- Brooklyn
- State
- NY
- ZipCode
- 11219
- Phone Number
- 929.810.5089
- Web Address
- www.ForestLeaf.com
DHEA Ultra 100 mg by ForestLeaf: Common Questions
Does DHEA Ultra 100 mg by ForestLeaf interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is DHEA safe to use long-term?
What are the most common side effects?
Can I take DHEA Ultra if I'm pregnant or breastfeeding?
What is DHEA, and what does it do in the body?
Does DHEA Ultra really work for depression?
Will DHEA affect how my cancer medications work?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if DHEA Ultra 100 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind DHEA Ultra 100 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
DHEA Ultra 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 98 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Dhea 98 references
- Frye RF, Kroboth PD, Folan MM, et al. Effect of DHEA on CYP3A-mediated metabolism of triazolam. Clin Pharmacol Ther 2000;67:109 (abstract PI-82).
- Kuritzky L. DHEA: Science or wishful thinking? Hosp Pract 1998;33:85-6. PubMed
- Van Vollenhoven RF, Morabito LM, Engleman EG, et al. Treatment of systemic lupus erythematosus with dehydroepiandrosterone: 50 patients treated up to 12 months. J Rheumatol 1998;25:285-9.
- Van Vollenhoven RF, Engleman EG, McGurie JL. Dehydroepiandrosterone in Systemic Lupus Erythematosus. Arth Rheum 1995;38:1826-31. DOI
- Ebeling P, Koivisto VA. Physiological importance of dehydroepiandrosterone. Lancet 1994;343:1479-81. PubMed
- Yen SS, Morales AJ, Khorram O. Replacement of DHEA in aging men and women. Potential remedial effects. Ann N Y Acad Sci 1995;774:128-42. PubMed
- Labrie F, Diamond P, Cusan L, et al. Effect of 12 month dehydroepiandrosterone replacement therapy on bone, vagina, and endometrium in postmenopausal women. J Clin Endocrinol Metab 1997;82:3498-505. PubMed
- Casson PR, Faquin LC, Stentz FB. Replacement of dehydroepiandrosterone enhances T-lymphocyte insulin binding in postmenopausal women. (abstract) Fertil Steril 1995;63:1027-31. DOI
- Morales AJ, Haubrich RH, Hwang JY, et al. The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women. Clin Endocrinol (Oxf)1 PubMed
- Arlt W, Justl H, Callies F, et al. Oral dehydroepiandrosterone for adrenal androgen replacement: pharmacokinetics and peripheral conversion to androgens and estrogens in young healthy females after dexamethasone suppression. [Abstract] J Clin Endocrinol PubMed
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