Interactions on record — worth a quick check against your medications. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

Digestive Support Ingredients & Drug Interactions

by Herbal Zap

Digestive Support label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Digestive Support against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Digestive Support is a dietary supplement by Herbal Zap with 6 active ingredients. Its ingredients are commonly taken for digestive upset and gas, appetite stimulation, mild antimicrobial (topical).Based on those ingredients, 1,297 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are dried Grapes, Coriander, Amla. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Digestive Support by Herbal Zap

Ask about any prescription or over-the-counter medication and we check it for interactions with Digestive Support by Herbal Zap — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Digestive Support by Herbal Zap

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Herbal Extract Proprietary Blend” is a proprietary blend — the label gives one combined amount (100 mg) without saying how much of each component you get.

Herbal Zap's Digestive Support is a powder containing five active ingredients. Coriander and dried grapes are the primary components, alongside amla (Indian gooseberry), vasaka (Malabar nut), and a proprietary herbal extract blend.

The product also contains cane sugar as an inactive ingredient. Each of these botanicals has a traditional role in digestive or respiratory wellness, though the evidence behind their effectiveness varies.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • The label markets general wellness (“digestive support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Chronic venous insufficiency (CVI) — rated "Possibly Effective" (Grape) (Natural Medicines).
  • On file: Dyslipidemia — rated "Possibly Effective" (Indian Gooseberry) (Natural Medicines).
  • On file: Gastroesophageal reflux disease (GERD) — rated "Possibly Effective" (Indian Gooseberry) (Natural Medicines).

The evidence for this product's ingredients is mixed. Amla is possibly effective for gastroesophageal reflux disease (GERD) and dyslipidemia (abnormal blood fats), and dried grapes are possibly effective for chronic venous insufficiency (poor circulation in the legs).

However, coriander has insufficient evidence for the conditions listed on this product—anorexia, anxiety, constipation, diabetes, diarrhea, and dyspepsia (indigestion) are all rated insufficient data. Dried grapes are also rated possibly ineffective for chemotherapy nausea, hay fever, and obesity.

Vasaka and the proprietary blend lack established evidence in our data. If you're considering this for a specific digestive concern, talk with your doctor or pharmacist about whether the evidence supports it for your situation.

The evidence, ingredient by ingredient Coriander Indian Gooseberry Grape Malabar Nut

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Coriander is generally well tolerated at food amounts, though medicinal doses lack solid safety data—concentrated forms and essential oils should be avoided without medical advice. Amla is generally well tolerated as a food but supplement safety is less studied; notably, the safety data advise against supplement doses.

Dried grapes are safe as fruit and grape seed extract appears well tolerated in studies. In clinical trials, a small number of participants taking amla reported epigastric discomfort or dyspepsia, and rare cases of anaphylaxis have been reported with both coriander and grapes in sensitive individuals.

Vasaka safety data are limited; it has traditionally been linked to uterine effects. For pregnancy and breastfeeding, there isn't enough data to know whether coriander or amla are safe—talk with your doctor or pharmacist for personalized advice.

Dried grapes as food are fine in pregnancy, but concentrated supplements should be avoided. Vasaka is rated unsafe in pregnancy and insufficient data exists for breastfeeding.

Side effects, ingredient by ingredient Coriander Indian Gooseberry Grape Malabar Nut

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Coriander, Grape, Indian Gooseberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 1,298 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your pharmacist if you're on blood thinners or antiplatelet drugs (such as warfarin, aspirin, or clopidogrel)—amla and grapes may increase bleeding risk. If you take antihypertensive drugs (for high blood pressure), diabetes medications, or CNS depressants (like sedatives or sleep aids), coriander raises theoretical risks of dizziness, low blood sugar, or extra drowsiness.

Dried grapes also interact with medications processed through your liver's CYP enzymes—a huge category that includes many common drugs—so a full medication review is essential. If you take cyclosporine, midazolam, or photosensitizing drugs, talk with your pharmacist about this product too.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product brings together ingredients with some traditional digestive and respiratory use, but the scientific evidence is thin for most of the conditions you might be taking it for. More importantly, the interactions—especially with blood thinners, diabetes drugs, and certain heart and enzyme-affecting medications—are substantial.

If you're on any prescription medications, check them against this product's ingredients with your own doctor or pharmacist before you start. If you're pregnant or breastfeeding, discuss it with your healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Digestive Support, straight from the product label.

Brand Herbal Zap
Barcode (UPC) 852486005037
Net contents 25 Individual Packet(s); 3.53 Oz(s); 100 Gram(s)
Market status On market
Date entered into DSLD Mar 23, 2018
DSLD ID 175094
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Digestive Support by Herbal Zap, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gram(s)
Maximum serving Sizes:
8 Gram(s)
UPC/BARCODE
852486005037
IngredientAmount% DV
Calories15 Calorie(s)--
Total Carbohydrates3.9 Gram(s)1%
Sugar3.9 Gram(s)--
Coriander0 NP--
Amla0 NP--
Herbal Extract Proprietary Blend100 mg--
dried Grapes0 NP--
Vasaka0 NP--
Parpataka0 NP--

Other ingredients: Cane Sugar

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Enjoy hot or cold Easy on the go

Sip to support your body's natural healing power, anytime.

Dissolves instantly - enjoy hot or cold

Suggested Use: For soothing digestive support dissolve 1-2 packets in 6oz hot or cold water, stir and enjoy! Drink as needed, up to 4 times daily. Children 3 & Up: Use 1/2 packet, up to 4 times daily.

General Statements

Ancient wisdom That's good to go When To Sip How It Works Uphill Down dog Fly high Mellow out Run wild Rock on Working with top physicians, we craft each concentrated, herbal formula with the ancient wisdom of Ayurveda.

Dissolves instantly!

Our Commitment: We source our herbs from small, sustainable farms to ensure the highest quality, potency and purity. Fair trade farming feels good, soil-to-sip. We proudly support Guria, a non-profit fighting the effects and causes of human trafficking in India.

This box is 100% recycled and was processed chlorine free. Please recycle.

Made with love in Sri Lanka

Ancient Ayurvedic herbal blend for Digestive Support

4 concentrated ayurvedic herbal extracts Be Soothed Cultivate your inner cool.

Calming, from the inside out.

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Non GMO Project Verified nongmoproject.org

Formulation

Non GMO

Gluten free

Vegan

Formula

Lightly sweet Amla fruit and ancient herbs help soothe irritation from acidic foods or sensitivities, and support digestive function.

Amla Calming digestive support Parpataka Soothing & harmonizing Coriander Calming digestion support Vasaka Supports digestion & immunity

Kosher

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Digestive Support by Herbal Zap label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Digestive Support label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Digestive Support by Herbal Zap

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gram(s) Dosage formPowder Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

3.9 Gram(s) per serving

Herbal Extract Proprietary Blend

100 mg per serving

Other (inactive) ingredients: Cane Sugar. These complete the product’s ingredient list but are not active constituents.

Interaction report

Digestive Support by Herbal Zap Drug Interactions

Want to check YOUR meds against Digestive Support?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,297Drugs
1,288 Moderate 9 Minor

Ingredients driving the most interactions

dried Grapes 910
Coriander 717
Amla 208

Individual Drug Interactions

The ingredients in Digestive Support interact with 1,297 drugs. Click any drug to see the details.

3 of the 6 ingredients in Digestive Support interact with drugs. Each result below shows which ingredient is responsible. dried Grapes Coriander Amla

Each ingredient & the kinds of drugs it affects

For each ingredient in Digestive Support with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

dried Grapes9 drug types · 910 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro evidence suggests that grape extracts might decrease platelet aggregation.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

Ingesting grape juice with cyclosporine can reduce cyclosporine absorption.
A small pharmacokinetic study in healthy young adults shows that intake of purple grape juice 200 mL along with cyclosporine can decrease the absorption of cyclosporine by up to 30% when compared with water. Separate doses of grape juice and cyclosporine by at least 2 hours to avoid this interaction.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
A small pharmacokinetic study in healthy adults shows that ingestion of 200 mL of grape juice decreases phenacetin plasma levels. This is thought to be due to induction of CYP1A2.

Likelihood Possible Evidence B
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, grape seed extract may increase the levels of CYP2D6 substrates.
In vitro evidence suggests that grape seed extract might inhibit CYP2D6 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
In vitro and animal research suggests that grape seed proanthocyanidin extract inhibits CYP2E1 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
In vitro evidence suggests that grape seed extract might inhibit CYP3A4 enzymes. However, evidence from animal research shows that grape seed extract may induce CYP3A4 in the liver. So far, these interactions have not been reported in humans.

Likelihood Possible Evidence D
Midazolam (Versed)

Theoretically, long-term intake of grape seed extract might decrease the effects of midazolam.
Animal research shows that subchronic ingestions of grape seed extract can increase the elimination of intravenous midazolam by increasing hepatic CYP3A4 activity. Single doses of grape seed extract do not appear to affect midazolam elimination.

Likelihood Possible Evidence D
Phenacetin

Grape juice might decrease phenacetin absorption.
A small pharmacokinetic study in healthy adults shows that ingestion of 200 mL of grape juice decreases phenacetin plasma levels. This is thought to be due to induction of cytochrome P450 1A2 (CYP1A2).

Likelihood Possible Evidence B
Cytochrome P450 2C9 (Cyp2C9) Substrates

It is unclear if grape juice or grape seed extract inhibits CYP2C9; research is conflicting.
In vitro evidence shows that grape seed extract or grape juice might inhibit CYP2C9 enzymes. However, a small pharmacokinetic study in healthy adults shows that drinking 8 ounces of grape juice once does not affect the clearance of flurbiprofen, a probe-drug for CYP2C9 metabolism. The effects of continued grape juice consumption are unclear.

Likelihood Unlikely Evidence D
dried Grapes full monograph & interactions

Coriander4 drug types · 717 drugs

Antidiabetes Drugs

Theoretically, coriander might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Evidence from animal research suggests that coriander fruit and coriander extract can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coriander might increase the risk of hypotension when taken with antihypertensive drugs.
Evidence from animal research suggests that coriander fruit can lower blood pressure.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, coriander might cause additive sedative effects when taken with CNS depressants.
Evidence from animal research suggests that coriander fruit extract has sedative effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, coriander might increase the risk of photosensitivity when taken with photosensitizing drugs.
Evidence from in vitro research suggests that coriandrin, a constituent of coriander, has photosensitizing effects.

Likelihood Possible Evidence D
Coriander full monograph & interactions

Amla4 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking Indian gooseberry 500 mg along with clopidogrel 75 mg or ecosprin 75 mg, as a single dose or for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg or ecosprin 75 mg alone. Until more is known, use caution when taking Indian gooseberry in combination with anticoagulant/antiplatelet drugs.

Likelihood Possible Evidence B
Antidiabetes Drugs

Taking Indian gooseberry with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking Indian gooseberry fruit or fruit extract alone or in conjunction with antidiabetes medications can lower blood glucose levels. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Aspirin

Theoretically, Indian gooseberry may increase the risk of bleeding if used with aspirin; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with ecosprin 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus ecosprin 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with ecosprin 75 mg alone.

Likelihood Possible Evidence B
Clopidogrel (Plavix)

Theoretically, Indian gooseberry may increase the risk of bleeding if used with clopidogrel; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with clopidogrel 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus clopidogrel 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg alone.

Likelihood Possible Evidence B
Amla full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Digestive Support, from the product label.

Herbal Zap

Name
Herbal Zap LLC
Street Address
P.O. Box 91446
City
Austin
State
TX
Phone Number
808-349-7710
Web Address
www.herbalzap.com
Pharmacist Counseling Corner

Digestive Support by Herbal Zap: Common Questions

Does Digestive Support by Herbal Zap interact with any medications?
Yes. Based on its ingredients, Digestive Support has a known interaction with 1,297 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Digestive Support contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while I'm pregnant?
There isn't enough data to know whether coriander or amla are safe in pregnancy. Vasaka is rated unsafe in pregnancy due to traditional links to uterine effects. Talk with your doctor or pharmacist before taking this product if you're pregnant or planning to become pregnant—they can advise you based on your individual situation.
Can I breastfeed while using this?
There isn't enough safety information on coriander or amla during breastfeeding, and vasaka should be avoided. The product facts don't provide enough data to say it's safe. Check with your pharmacist or doctor before starting if you're nursing.
What does amla actually do in this blend?
Amla (Indian gooseberry) is possibly effective for gastroesophageal reflux disease (GERD)—a condition where stomach acid backs up into your throat—and for improving blood fat levels. It's not proven to work for other conditions the product may claim.
Does this product have any fillers?
Yes. Cane sugar is listed as an inactive ingredient, so it's included as a filler or sweetener in the powder.
Are there any common side effects I should expect?
Most people tolerate these ingredients well. In clinical trials, a small number of people taking amla reported indigestion or upset stomach. Rare cases of allergic reactions (rash, difficulty breathing) have been reported with coriander and grapes in sensitive individuals, especially those with spice allergies.
Does this really help with digestion?
The evidence is weak. Coriander has insufficient evidence for most digestive complaints listed on this product. Amla is possibly effective for acid reflux and high cholesterol, but not proven for general digestion. If you have a specific digestive issue, talk with your doctor about what the science actually supports.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Digestive Support is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Digestive Support label
Go deeper

The Full Monographs Behind Digestive Support’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Coriander

Interacts with 717 drugs

Coriander (also called cilantro) is a common cooking herb and spice that has long been used in traditional medicine for digestive complaints. As a food it is generally safe for most people,...

Read the full Coriander monograph → Herb & supplement monograph

Indian Gooseberry

Interacts with 208 drugs

Indian gooseberry (amla) is a vitamin C-rich fruit used in Ayurvedic medicine for many purposes, from antioxidant support to cholesterol and digestion. Early research is promising for some u...

Read the full Indian Gooseberry monograph → Herb & supplement monograph

Grape

Interacts with 910 drugs

Grapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support heart and blood vessel health. While the food is he...

Read the full Grape monograph → Herb & supplement monograph

Malabar Nut

Malabar nut (vasaka) is a traditional Ayurvedic herb used mostly for coughs and other breathing problems. Lab and animal studies suggest its compounds may help loosen mucus and relax airways...

Read the full Malabar Nut monograph →
Sources

Sources & How We Checked

Digestive Support's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 57 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Coriander 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4. PubMed
  3. Gray, A. M. and Flatt, P. R. Insulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander). Br.J Nutr. 1999;81(3):203-209.
  4. Kanerva, L. and Soini, M. Occupational protein contact dermatitis from coriander. Contact Dermatitis 2001;45(6):354-355. PubMed
  5. Emamghoreishi, M., Khasaki, M., and Aazam, M. F. Coriandrum sativum: evaluation of its anxiolytic effect in the elevated plus-maze. J Ethnopharmacol. 1-15-2005;96(3):365-370. PubMed
  6. Ebo, D. G., Bridts, C. H., Mertens, M. H., and Stevens, W. J. Coriander anaphylaxis in a spice grinder with undetected occupational allergy. Acta Clin Belg. 2006;61(3):152-156. PubMed
  7. Eidi, M., Eidi, A., Saeidi, A., Molanaei, S., Sadeghipour, A., Bahar, M., and Bahar, K. Effect of coriander seed (Coriandrum sativum L.) ethanol extract on insulin release from pancreatic beta cells in streptozotocin-induced diabetic rats. Phytother.Res
  8. Jabeen, Q., Bashir, S., Lyoussi, B., and Gilani, A. H. Coriander fruit exhibits gut modulatory, blood pressure lowering and diuretic activities. J Ethnopharmacol. 2-25-2009;122(1):123-130. PubMed
  9. van Toorenenbergen, A. W. and Dieges, P. H. Immunoglobulin E antibodies against coriander and other spices. J Allergy Clin Immunol. 1985;76(3):477-481. PubMed
  10. Ashwood-Smith, M. J., Warrington, P. J., Jenkins, M., Ceska, O., and Romaniuk, P. J. Photobiological properties of a novel, naturally occurring furoisocoumarin, coriandrin. Photochem.Photobiol. 1989;50(6):745-751. PubMed
  11. Sastre, J., Olmo, M., Novalvos, A., Ibanez, D., and Lahoz, C. Occupational asthma due to different spices. Allergy 1996;51(2):117-120. PubMed
  12. Beikert FC, Anastasiadou Z, Fritzen B, Frank U, Augustin M. Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study. Dermatology. 2013;226(1):47-51. PubMed

See these in context on the Coriander monograph →

Indian Gooseberry 6 references
  1. Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
  2. Fatima N, Pingali U, Muralidhar N. Study of pharmacodynamic interaction of Phyllanthus emblica extract with clopidogrel and ecosprin in patients with type II diabetes mellitus. Phytomedicine. 2014;21(5):579-85. PubMed
  3. Shanmugarajan D, Girish C, Harivenkatesh N, Chanaveerappa B, Prasanna Lakshmi NC. Antihypertensive and pleiotropic effects of Phyllanthus emblica extract as an add-on therapy in patients with essential hypertension-A randomized double-blind placebo-contro
  4. Akhtar MS, Ramzan A, Ali A, Ahmad M. Effect of amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients. Int J Food Sci Nutr. 2011;62(6):609-16.
  5. Usharani P, Fatima N, Muralidhar N. Effects of Phyllanthus emblica extract on endothelial dysfunction and biomarkers of oxidative stress in patients with type 2 diabetes mellitus: a randomized, double-blind, controlled study. Diabetes Metab Syndr Obes. 20 PubMed
  6. Majeed M, Mundkur L, Paulose S, Nagabhushanam K. Novel Emblica officinalis extract containing ß-glucogallin vs. metformin: a randomized, open-label, comparative efficacy study in newly diagnosed type 2 diabetes mellitus patients with dyslipidemia. Food Fu

See these in context on the Indian Gooseberry monograph →

Grape 34 references
  1. Kiesewetter H, Koscielny J, Kalus U, et al. Efficacy of orally administered extract of red vine leaf AS 195 (folia vitis viniferae) in chronic venous insufficiency (stages I-II). A randomized, double-blind, placebo-controlled trial. Arzneimittelforschung
  2. Xiao Dong S, Zhi Ping Z, Zhong Xiao W, et al. Possible enhancement of the first-pass metabolism of phenacetin by ingestion of grape juice in Chinese subjects. Br J Clin Pharmacol 1999;48:638-40. PubMed
  3. Vaswani SK, Hamilton RG, Carey RN, et al. Anaphylaxis recurrent urticaria and angioedema from grape hypersensitivity. J Allergy Clin Immunol 1998;101:S31.
  4. Chevallier A. The Encyclopedia of Medicinal Plants. London, UK: Dorling Kindersley, Ltd., 1996.
  5. Bernstein DI, Bernstein CK, Deng C, et al. Evaluation of the clinical efficacy and safety of grapeseed extract in the treatment of fall seasonal allergic rhinitis: a pilot study. Ann Allergy Asthma Immunol 2002;88:272-8.. PubMed
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Malabar Nut 5 references
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See these in context on the Malabar Nut monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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