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Dietary supplement

Diuretic Formula Ingredients & Drug Interactions

by TerraVita

Diuretic Formula label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Diuretic Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Diuretic Formula is a dietary supplement by TerraVita with 2 active ingredients. Its ingredients are commonly taken for fluid retention (mild diuretic), urinary and bladder concerns, hair, skin, and nail support.Based on those ingredients, 292 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Horsetail Glycerite Liquid Extract, Java Tea Glycerite Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Diuretic Formula by TerraVita

Ask about any prescription or over-the-counter medication and we check it for interactions with Diuretic Formula by TerraVita — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Diuretic Formula by TerraVita

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (0.13 mL) without saying how much of each component you get.

This liquid contains 2 active ingredients: horsetail glycerite liquid extract and Java tea glycerite liquid extract. Both are plant extracts delivered in a base of glycerin, an inactive carrier.

Horsetail has been used traditionally for its diuretic properties — it's believed to increase urine output. Java tea, also called kidney tea, is similarly used as a diuretic support.

The product also contains glycerin as an inactive ingredient.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: mild diuretic and urinary tract support.
  • We looked for evidence on: Urinary tract infections (UTIs), Hypertension, fluid retention, edema, kidney function.
  • The closest evidence on file: Java Tea is rated "Insufficient Reliable Evidence To Rate" for Hypertension (Natural Medicines).
  • Also on file: Java Tea is rated "Insufficient Reliable Evidence To Rate" for Urinary tract infections (UTIs).
  • Also on file: Horsetail is rated "Insufficient Reliable Evidence To Rate" for Hypertension, Urinary tract infections (UTIs).

The evidence for either ingredient is insufficient to establish whether they actually work. Horsetail has been studied for urinary incontinence, obesity, tonsillitis, and hair loss, but the data we hold show no reliable evidence rating for any of those uses.

Java tea has been evaluated for high blood pressure and urinary tract infections, with the same result — insufficient evidence. If you're considering this product for a specific health goal, talk it over with your doctor or pharmacist to see what the clinical evidence really supports.

The evidence, ingredient by ingredient Horsetail Java Tea

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Horsetail is generally well tolerated short-term in healthy adults, but long-term use carries real risks that aren't fully understood. The most common side effects from horsetail are abdominal bloating, increased bowel movements, and nausea.

One concern is thiamine (vitamin B1) deficiency with prolonged use — crude horsetail contains an enzyme that breaks down thiamine, though products certified as thiaminase-free are safer. There's also one case report of a skin reaction to horsetail applied topically.

Java tea is considered generally well tolerated short-term, though human safety data are limited. Horsetail is not recommended during pregnancy or breastfeeding due to insufficient safety data.

The same applies to Java tea. If you're pregnant, breastfeeding, or planning to become pregnant, talk with your doctor or pharmacist before using this product.

Side effects, ingredient by ingredient Horsetail Java Tea

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Java Tea, Horsetail.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 292 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking if you use nucleoside reverse transcriptase inhibitors (NRTIs) or efavirenz for HIV — horsetail may reduce their effectiveness. Also verify use if you take antidiabetes drugs (horsetail may increase low blood sugar risk), other diuretics (both ingredients may worsen potassium loss), lithium (both may increase its levels), or blood pressure medications (Java tea may lower blood pressure further).

Run your exact medications through the search tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product combines two plant diuretics, but evidence that either one actually works for its intended purpose hasn't been established. The real concern is medication interactions — particularly if you take HIV medications, blood pressure drugs, diabetes medications, other diuretics, or lithium.

If any of those apply to you, check your specific medications with the tool on this page before starting, and discuss it with your own doctor or pharmacist. It's fine short-term in healthy adults with no relevant medications, but long-term safety isn't well understood.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Diuretic Formula, straight from the product label.

Brand TerraVita
Barcode (UPC) 064435237967
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 281974
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Diuretic Formula by TerraVita, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
25 Drop(s)
Maximum serving Sizes:
40 Drop(s)
Servings per container
227
UPC/BARCODE
064435237967
IngredientAmount% DV
Proprietary Blend0.13 mL--
Horsetail Glycerite Liquid Extract0 NP--
Java Tea Glycerite Liquid Extract0 NP--

Other ingredients: Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Copyright 2018 TerraVita Distributed by ZooScape LLC, All Rights Reserved.

Formula

Glycerite liquid extract (1:5)

Formulation

Alcohol free

No flavor

Suggested/Recommended/Usage/Directions

Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.

Precautions

Keep away from children.

Do not use if safety seal around cap is broken or missing.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Diuretic Formula by TerraVita label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Diuretic Formula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Diuretic Formula by TerraVita

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

0.13 mL per serving

Other (inactive) ingredients: Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Diuretic Formula by TerraVita Drug Interactions

Want to check YOUR meds against Diuretic Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
292Drugs
292 Moderate

Ingredients driving the most interactions

Horsetail Glycerite Liquid Extract 188
Java Tea Glycerite Liquid Extract 173

Individual Drug Interactions

The ingredients in Diuretic Formula interact with 292 drugs. Click any drug to see the details.

2 of the 2 ingredients in Diuretic Formula interact with drugs. Each result below shows which ingredient is responsible. Horsetail Glycerite Liquid Extract Java Tea Glycerite Liquid Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Diuretic Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Horsetail Glycerite Liquid Extract5 drug types · 188 drugs

Antidiabetes Drugs

Theoretically, taking horsetail with antidiabetes drugs might increase the risk of hypoglycemia.
Equisetum myriochaetum has demonstrated hypoglycemic activity in clinical research. In an animal diabetic model, Equisetum giganteum had hypoglycemic effects. It is unclear whether other horsetail species have hypoglycemic effects.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, taking horsetail with diuretic drugs might increase potassium loss and the risk of hypokalemia.
Laboratory research shows that various species of horsetail have diuretic properties. Due to its diuretic effects, there has been concern that taking horsetail along with potassium-depleting diuretics might increase the risk for hypokalemia. However, pharmacokinetic research in humans shows that taking horsetail 900 mg daily for 4 days does not affect urinary excretion of electrolytes, including potassium and sodium, despite having a diuretic effect similar to taking hydrochlorothiazide 25 mg daily. It is unclear if taking horsetail for a longer duration would affect electrolyte levels. Until more is known, use with caution.

Likelihood Possible Evidence D
Efavirenz (Sustiva)

Theoretically, horsetail might decrease the levels and clinical effects of efavirenz.
In two case reports, patients were found to have detectable viral loads when taking horsetail-containing supplements along with an antiretroviral regimen that included efavirenz. In one case, the antiretroviral regimen included zidovudine, lamivudine, and efavirenz; in the other case, the regimen consisted of emtricitabine, tenofovir disoproxil fumarate, and efavirenz. One month after discontinuing horsetail, the viral loads became undetectable in both cases. The exact mechanism of this interaction is unknown. It is also unclear if this interaction is specific to efavirenz or if it is related to various components of antiretroviral therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, horsetail might increase the levels and adverse effects of lithium.
Animal research suggests that horsetail has diuretic properties. Theoretically, due to these potential diuretic effects, horsetail might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Nucleoside Reverse Transcriptase Inhibitors (Nrtis)

Theoretically, horsetail might decrease the levels and clinical effects of NRTIs.
In two case reports, patients were found to have detectable viral loads when taking horsetail-containing supplements along with an antiretroviral therapy. In one case, the antiretroviral regimen included zidovudine, lamivudine, and efavirenz; in the other case, the regimen consisted of emtricitabine, tenofovir disoproxil fumarate, and efavirenz. One month after discontinuing the supplement, the viral loads became undetectable in both cases. The exact mechanism of these interactions is unknown. It is also unclear if these interactions are specific to NRTIs or if they are related to various components of antiretroviral therapy.

Likelihood Possible Evidence D
Horsetail Glycerite Liquid Extract full monograph & interactions

Java Tea Glycerite Liquid Extract2 drug types · 173 drugs

Antihypertensive Drugs

Some preliminary clinical evidence suggests that Java tea has antihypertensive effects. Further, animal research suggests that Java tea has diuretic properties. Theoretically, taking Java tea with other antihypertensive drugs might increase the effects and risk for hypotension with these drugs.

Likelihood Probable Evidence D
Lithium

Animal research suggests that Java tea has diuretic properties. Theoretically, due to these effects, Java tea might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Java Tea Glycerite Liquid Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Diuretic Formula, from the product label.

TerraVita

See all TerraVita products
Name
ZooScape LLC
Phone Number
844-449-0444
Web Address
www.ZooScape.com
Pharmacist Counseling Corner

Diuretic Formula by TerraVita: Common Questions

Does Diuretic Formula by TerraVita interact with any medications?
Yes. Based on its ingredients, Diuretic Formula has a known interaction with 292 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Diuretic Formula contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on blood pressure medication?
Java tea in this formula may lower blood pressure further, so combining it with blood pressure drugs could increase the risk of your pressure dropping too much. Check with your doctor or pharmacist before taking it alongside any blood pressure medication.
Is horsetail safe to use long-term?
The safety data suggest it's okay short-term in healthy adults, but long-term use carries real risks we don't fully understand. Crude horsetail can also cause thiamine deficiency if used for extended periods — though certified thiaminase-free products are safer. If you're thinking of using it regularly, talk with your pharmacist or doctor first.
What are the most common side effects?
Horsetail may cause abdominal bloating, increased bowel movements, and nausea. These are the most frequently reported effects from the limited research available. If you experience any of these, stop and let your doctor know.
Can I take this during pregnancy?
No — there isn't enough safety data for either horsetail or Java tea during pregnancy, so both are best avoided. Talk with your doctor or pharmacist for personalized advice if you're pregnant or planning to become pregnant.
Does this product actually work for water retention or bloating?
The evidence we have doesn't support that either ingredient reliably works for any specific health condition. Both have been studied for several uses — horsetail for incontinence and hair loss, Java tea for blood pressure and urinary tract infections — but none of those uses have sufficient evidence. If you're looking for relief from water retention, ask your doctor what the science actually supports.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Diuretic Formula label
Go deeper

The Full Monographs Behind Diuretic Formula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Horsetail

Interacts with 188 drugs

Horsetail is a traditional herb most often used as a mild diuretic and for hair, nail, and bone support, but high-quality human evidence is limited. It can cause thiamine (vitamin B1) loss w...

Read the full Horsetail monograph → Herb & supplement monograph

Java Tea

Interacts with 173 drugs

Java Tea is a Southeast Asian herb traditionally used as a gentle diuretic and for urinary tract and kidney support. Some early lab, animal, and small human studies are encouraging, but high...

Read the full Java Tea monograph →
Sources

Sources & How We Checked

Diuretic Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Horsetail 14 references
  1. Sudan BJ. Seborrhoeic dermatitis induced by nicotine of horsetails (Equisetum arvense L.). Contact Dermatitis 1985;13:201-2.
  2. Perez Gutierrez RM, Laguna GY, Walkowski A. Diuretic activity of Mexican equisetum. J Ethnopharmacol 1985;14:269-72. PubMed
  3. Lemus I, Garcia R, Erazo S, et al. Diuretic activity of an Equisetum bogotense tea (Platero herb): evaluation in healthy volunteers. J Ethnopharmacol 1996;54:55-8. PubMed
  4. Revilla MC, Andrade-Cetto A, Islas S, Wiedenfeld H. Hypoglycemic effect of Equisetum myriochaetum aerial parts on type 2 diabetic patients. J Ethnopharmacol 2002;81:117-20. PubMed
  5. Tiktinskii, O. L. and Bablumian, I. A. [Therapeutic action of Java tea and field horsetail in uric acid diathesis]. Urol.Nefrol.(Mosk) 1983;3(1):47-50.
  6. Henderson JA, Evans EV, and McIntosh RA. The antithiamine action of Equisetum. J Amer Vet Med Assoc 1952;120:375-378.
  7. Carneiro DM, Freire RC, Honório TC, Zoghaib I, Cardoso FF, Tresvenzol LM, de Paula JR, Sousa AL, Jardim PC, da Cunha LC. Randomized, Double-Blind Clinical Trial to Assess the Acute Diuretic Effect of Equisetum arvense (Field Horsetail) in Healthy Voluntee
  8. Klnçalp S, Ekiz F, Basar Ö, Coban S, Yüksel O. Equisetum arvense (Field Horsetail)-induced liver injury. Eur J Gastroenterol Hepatol. 2012 Feb;24(2):213-4. PubMed
  9. Ortega García JA, Angulo MG, Sobrino-Najul EJ, Soldin OP, Mira AP, Martínez-Salcedo E, Claudio L. Prenatal exposure of a girl with autism spectrum disorder to 'horsetail' (Equisetum arvense) herbal remedy and alcohol: a case report. J Med Case Rep. 2011 M PubMed
  10. Cordova E, Morganti L, Rodriguez C. Possible Drug-Herb Interaction between Herbal Supplement Containing Horsetail (Equisetum arvense) and Antiretroviral Drugs. J Int Assoc Provid AIDS Care. 2017;16(1):11-13.
  11. García Gavilán MD, Moreno García AM, Rosales Zabal JM, Navarro Jarabo JM, Sánchez Cantos A. Case of drug-induced acute pancreatitis produced by horsetail infusions. Rev Esp Enferm Dig. 2017 Apr;109(4):301-304. PubMed
  12. Vieira GT, de Oliveira TT, Carneiro MAA, et al. Antidiabetic effect of Equisetum giganteum L. extract on alloxan-diabetic rabbit. J Ethnopharmacol. 2020;260:112898. PubMed
  13. Health Canada. Organism-Equisetum arvense. Available at: http://webprod.hc-sc.gc.ca/nhpid-bdipsn/ingredReq.do?id=6117&lang=eng. Accessed 21-July 2021.
  14. Bates D, Duong TB, Kheyson S, Moore K. Hyponatremia Secondary to Decreased Oral Intake and SIADH and Possibly Exacerbated by Horsetail (Equisetum arvense). Can J Hosp Pharm 2021;74(4):386-389. PubMed

See these in context on the Horsetail monograph →

Java Tea 2 references
  1. Cicero AF, De Sando V, Izzo R, Vasta A, Trimarco A, Borghi C. Effect of a combined nutraceutical containing Orthosiphon stamineus effect on blood pressure and metabolic syndrome components in hypertensive dyslipidaemic patients: a randomized clinical tria
  2. Vahlensieck W, Lorenz H, Schumacher-Stimpfl A, Fischer R, Naber KG. Effect of a herbal therapy on clinical symptoms of acute lower uncomplicated urinary tract infections in women: Secondary analysis from a randomized controlled trial. Antibiotics (Basel). PubMed

See these in context on the Java Tea monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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