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Dietary supplement

DMAE L-Bitartrate Capsules 350 mg Ingredients & Drug Interactions

by Nootropics Depot

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

DMAE L-Bitartrate Capsules 350 mg is a dietary supplement by Nootropics Depot with 1 active ingredient. Its ingredients are commonly taken for memory and focus, mood and mental clarity, adhd-type symptoms.Based on those ingredients, 219 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are DMAE L-Bitartrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of DMAE L-Bitartrate Capsules 350 mg by Nootropics Depot

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: DMAE L-Bitartrate (deanol), 350 mg per capsule. The inactive ingredients are magnesium stearate, silicon dioxide, and vegetable cellulose — standard capsule fillers and binders.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Deanol product and its label doesn't state a use — see Deanol's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for deanol is limited. For Alzheimer disease, it's been rated likely ineffective.

For tardive dyskinesia (involuntary movements), the data also points to likely ineffective. For aging skin, ADHD, and athletic performance, there isn't enough reliable evidence to establish whether it works.

The science on this ingredient doesn't support its use for these purposes.

The evidence, ingredient by ingredient Deanol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Deanol is generally well tolerated orally, but side effects do occur in some people. The most common are abdominal cramps, pain, diarrhea, drowsiness, nausea, and vomiting.

Less often, it's been reported to cause constipation, headache, insomnia, overstimulation, vivid dreams, confusion, mood changes including depression and mania, and in people with schizophrenia, worsening of symptoms — especially at doses above 1,000 mg daily. The safety data during pregnancy is not available; there isn't enough information to know either way, so talk with your doctor or pharmacist about whether this is right for you if you're pregnant.

It's not recommended during breastfeeding, as safety data are lacking.

Side effects, ingredient by ingredient Deanol

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Deanol.
  • The most serious interaction on file is rated Minor.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check whether you're on anticholinergic drugs or cholinergic drugs. Both medication types could have their effects or side effects altered by deanol.

Use the search tool on this page to verify your exact medications, and talk with your doctor or pharmacist about whether it's safe for you.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

DMAE L-Bitartrate has limited evidence behind it for any of its common uses and carries a real risk of digestive upset and mood changes in some people. If you take anticholinergic or cholinergic medications, you'll need to check this product against your exact prescriptions first.

Talk with your doctor or pharmacist before starting it — they can weigh the evidence and your individual health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about DMAE L-Bitartrate Capsules 350 mg, straight from the product label.

Brand Nootropics Depot
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 251497
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for DMAE L-Bitartrate Capsules 350 mg by Nootropics Depot, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
180
IngredientAmount% DV
DMAE L-Bitartrate350 mg--

Other ingredients: Magnesium Stearate, Silicon Dioxide, Vegetable Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Precautions

Disclaimer: Always consult with a qualified health physician before taking any new dietary supplement.

Warning: Keep out of reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drug(s) or OTC medication(s).

Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drug(s) or OTC medication(s).

FDA Disclaimer Statement

This product is not intended to diagnose, treat, cure or prevent any diseases. These statements have not been evaluated by the Food & Drug Administration.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 capsule daily.

Storage

Storage: Store in a cool and dry place. Keep away from direct sunlight and heat.

General Statements

Lot: DMECS2111720

See for yourself

DMAE L-Bitartrate Capsules 350 mg by Nootropics Depot label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in DMAE L-Bitartrate Capsules 350 mg by Nootropics Depot

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

DMAE L-Bitartrate

Interacts with
219 drugs
350 mg per serving

Deanol (DMAE) is a compound related to choline that is marketed for memory, focus, and mood, but solid human evidence for most of these uses is limite...

DMAE L-Bitartrate monograph & interactions

Other (inactive) ingredients: Magnesium Stearate, Silicon Dioxide, Vegetable Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

DMAE L-Bitartrate Capsules 350 mg by Nootropics Depot Drug Interactions

Want to check YOUR meds against DMAE L-Bitartrate Capsules 350 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
219Drugs
219 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in DMAE L-Bitartrate Capsules 350 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

DMAE L-Bitartrate2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
Cholinergic Drugs

Theoretically, deanol might increase the effects and adverse effects of cholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for DMAE L-Bitartrate Capsules 350 mg, from the product label.

Nootropics Depot

See all Nootropics Depot products
Name
Nootropics Depot
Street Address
8380 S. Kyrene Rd. Ste. 110
City
Tempe
State
AZ
ZipCode
85284
Web Address
nootropicsdepot.com
Pharmacist Counseling Corner

DMAE L-Bitartrate Capsules 350 mg by Nootropics Depot: Common Questions

Does DMAE L-Bitartrate Capsules 350 mg by Nootropics Depot interact with any medications?
Yes. Based on its ingredients, DMAE L-Bitartrate Capsules 350 mg has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
DMAE L-Bitartrate Capsules 350 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take DMAE L-Bitartrate while pregnant?
The safety data aren't available — there isn't enough information to know either way. Talk with your doctor or pharmacist about whether it's right for you during pregnancy; they can help you weigh what's known against your own health situation.
Is it safe to take while breastfeeding?
No — the safety data are lacking, so it's not recommended. If you're breastfeeding and interested in this product, check with your doctor or pharmacist first.
What are the most common side effects?
Abdominal cramps, abdominal pain, diarrhea, drowsiness, nausea, and vomiting. Most people tolerate it, but these do happen in some users.
Does DMAE help with ADHD?
There isn't enough reliable evidence to establish whether it works for ADHD. The science doesn't back its use for this condition.
Will this help my memory or Alzheimer disease?
No — deanol has been rated likely ineffective for Alzheimer disease. There's no evidence it helps with memory loss from this condition.
What is DMAE L-Bitartrate?
DMAE (dimethylaminoethanol), in the form of L-bitartrate, is thought to increase acetylcholine levels in the body. It's been studied for cognitive and skin health, but the evidence is weak or absent.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if DMAE L-Bitartrate Capsules 350 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

DMAE L-Bitartrate Capsules 350 mg label
Go deeper

The Full Monographs Behind DMAE L-Bitartrate Capsules 350 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

DMAE L-Bitartrate Capsules 350 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Deanol 15 references
  1. Davies C, Maidment S, Hanley P, et al. Dimethylaminoethanol (DMAE). HSE. Risk assessment document; EH72/2;1997. (TOXLINE).
  2. Re O. 2-Dimethylaminoethanol (deanol): a brief review of its clinical efficacy and postulated mechanism of action. Curr Ther Res Clin Exp 1974;16:1238-42.
  3. Pieralisi G, Ripari P, Vecchiet L. Effects of a standardized ginseng extract combined with dimethylaminoethanol bitartrate, vitamins, minerals, and trace elements on physical performance during exercise. Clin Ther 1991;13:373-82.
  4. George J, Pridmore S, Aldous D. Double blind controlled trial of deanol in tardive dyskinesia. Aust N Z J Psychiatry 1981;15:68-71. PubMed
  5. Penovich P, Morgan JP, Kerzner B, et al. Double-blind evaluation of deanol in tardive dyskinesia. JAMA 1978;239:1997-8. DOI
  6. de Montigny C, Chouinard G, Annable L. Ineffectiveness of deanol in tardive dyskinesia: a placebo controlled study. Psychopharmacology (Berl) 1979;65:219-23. PubMed
  7. Lindeboom SF, Lakke JP. Deanol and physostigmine in the treatment of L-dopa-induced dyskinesias. Acta Neurol Scand 1978;58:134-8. PubMed
  8. Jus A, Villeneuve A, Gautier J, et al. Deanol, lithium and placebo in the treatment of tardive dyskinesia. A double-blind crossover study. Neuropsychobiology 1978;4:140-9. PubMed
  9. Lewis JA, Young R. Deanol and methylphenidate in minimal brain dysfunction. Clin Pharmacol Ther 1975;17:534-40. PubMed
  10. Fisman M, Mersky H, Helmes E. Double-blind trial of 2-dimethylaminoethanol in Alzheimer's disease. Am J Psychiatry 1981;138:970-2. PubMed
  11. Ferris SH, Sathananthan G, Gershon S, et al. Senile dementia: treatment with deanol. J Am Geriatr Soc 1977;25:241-4. PubMed
  12. Haug BA, Holzgraefe M. Orofacial and respiratory tardive dyskinesia: potential side effects of 2-dimethylaminoethanol (deanol)? Eur Neurol 1991;31:423-5. PubMed
  13. Casey DE. Mood alterations during deanol therapy. Psychopharmacology (Berl) 1979;62:187-91. PubMed
  14. Sergio W. Use of DMAE (2-dimethylaminoethanol) in the induction of lucid dreams. Med Hypotheses 1988;26:255-7. PubMed
  15. Osol A, Hoover JE, eds. Remington's Pharmaceutical Science, 15th ed. Easton, PA: Mack Publishing Company, 1975.

See these in context on the Deanol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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