Interactions on record — worth a quick check against your medications. Based on 3 of 6 ingredients. Check your meds →
Dietary supplement

Elderberry Plus Syrup Ingredients & Drug Interactions

by Host Defense Mushrooms

Elderberry Plus Syrup label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Elderberry Plus Syrup against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Elderberry Plus Syrup is a dietary supplement by Host Defense Mushrooms with 6 active ingredients. Its ingredients are commonly taken for immune support, antioxidant support, general wellness/tonic.Based on those ingredients, 494 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi, Chaga, Black Elderberry Fruit Juice Concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Elderberry Plus Syrup by Host Defense Mushrooms

Ask about any prescription or over-the-counter medication and we check it for interactions with Elderberry Plus Syrup by Host Defense Mushrooms — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Elderberry Plus Syrup by Host Defense Mushrooms

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This syrup contains 6 ingredients, including four active mushroom and plant components. Chaga and reishi are medicinal mushrooms traditionally used for immune support.

Turkey tail is also a functional mushroom. Black elderberry—both juice concentrate and extract powder—comes from the ripe fruit and is included for its antioxidant properties.

The rest are inactive ingredients: cane sugar, glycerin, purified water, and ascorbic acid (vitamin C), which serve as sweeteners, preservatives, and stabilizers.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Immune support and respiratory health.
  • We looked for evidence on: Influenza, Lower respiratory tract infections, Upper respiratory tract infection (URTI), Respiratory tract infections, Bronchitis, Rhinosinusitis — and 4 related terms.
  • The closest evidence on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections, Rhinosinusitis, Upper respiratory tract infection (URTI), Lower respiratory tract infections.
  • Also on file: Reishi Mushroom is rated "Insufficient Reliable Evidence To Rate" for Bronchitis, Influenza.

The evidence we hold doesn't establish that these ingredients work for most conditions listed. Chaga, reishi, and elderberry all show insufficient reliable evidence for cardiovascular health, diabetes support, and respiratory infections.

Reishi is rated possibly ineffective for high cholesterol. None of the ingredients have strong clinical backing for the uses typically marketed for elderberry syrups—cough, cold duration, or immune boost—based on the data available to us.

The evidence, ingredient by ingredient Chaga Reishi Mushroom Elderberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Reishi is generally well tolerated short-term, but long-term safety isn't well studied. Common side effects include dizziness, dry mouth, itching, nausea, rash, and stomach upset; respiratory allergies to reishi spores can occur with sore throat or runny nose.

Elderberry extracts made from ripe, cooked fruit are generally well tolerated, but raw or unripe berries and plant parts are toxic. Chaga carries a caution because human safety data are limited; excessive consumption has been linked to kidney problems due to high oxalate content.

For pregnancy: chaga and reishi safety data aren't sufficient—avoid them during pregnancy and while breastfeeding. Elderberry also lacks reliable safety information in pregnancy and lactation, so it's best avoided.

If you're pregnant or nursing, talk with your doctor or pharmacist before use.

Side effects, ingredient by ingredient Chaga Reishi Mushroom Elderberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Elderberry, Reishi Mushroom, Chaga.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 494 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take blood thinners (anticoagulants or antiplatelet drugs)—both chaga and reishi may increase bleeding risk. Also double-check blood pressure medications (reishi may lower pressure further), diabetes drugs (chaga and reishi may lower blood sugar more), immunosuppressants (chaga and elderberry may reduce their effect), or pazopanib (a case of severe liver injury was reported with elderberry).

These are Moderate-severity interactions documented in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This syrup combines mushrooms and elderberry, neither of which has strong evidence for the effects commonly claimed. If you take blood thinners, blood pressure medications, diabetes drugs, immunosuppressants, or pazopanib, check with us first—the interactions are real and can be serious.

Pregnant or breastfeeding? Avoid it.

For everyone else, it's generally tolerated, but talk to your pharmacist about whether it fits your health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Elderberry Plus Syrup, straight from the product label.

Brand Host Defense Mushrooms
Barcode (UPC) (633422558271)
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 335812
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Elderberry Plus Syrup by Host Defense Mushrooms, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10 mL
Maximum serving Sizes:
10 mL
Servings per container
12
UPC/BARCODE
(633422558271)
IngredientAmount% DV
Calories30 Calorie(s)--
Total Carbohydrates8 Gram(s)3%
Added Sugars2 Gram(s)4%
Total Sugars3 Gram(s)--
Agarikon250 mg--
Chaga250 mg--
Reishi250 mg--
Turkey Tail250 mg--
Black Elderberry Fruit Juice Concentrate2 Gram(s)--
Black Elderberry Fruit Extract, Powder100 mg--

Other ingredients: Cane Sugar, Glycerin, Water, Purified, Ascorbic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Shake well. Take 2 tsp. as needed. Can be taken with food or on an empty stomach, or as recommended by your healthcare professional.

Precautions

Caution: If you have a medical condition, are taking medications, or are pregnant or breastfeeding, consult a healthcare professional before using this product.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Superfood mushroom mycelium Agarikon Chaga Reishi Turkey tail

Formulation

Non GMO Gluten free

Supports a healthy immune response

Certified Organic by the WSDA

Seals/Symbols

USDA Organic

Certified Organic Washington State Department of Agriculture Organic Program

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Elderberry Plus Syrup by Host Defense Mushrooms label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Elderberry Plus Syrup label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Elderberry Plus Syrup by Host Defense Mushrooms

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size10 mL Dosage formLiquid Servings per container12 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Agarikon

250 mg per serving

Chaga

Interacts with
327 drugs
250 mg per serving

Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for i...

Chaga monograph & interactions

Reishi

Interacts with
375 drugs
250 mg per serving

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits...

Reishi monograph & interactions

Turkey Tail

250 mg per serving

Black Elderberry Fruit Juice Concentrate

Interacts with
121 drugs
2 Gram(s) per serving

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...

Black Elderberry Fruit Juice Concentrate monograph & interactions

Black Elderberry Fruit Extract, Powder

Interacts with
121 drugs
100 mg per serving Form: Sambucus nigra Fruit Extract, Powder

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...

Black Elderberry Fruit Extract, Powder monograph & interactions

Other (inactive) ingredients: Cane Sugar, Glycerin, Water, Purified, Ascorbic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Elderberry Plus Syrup by Host Defense Mushrooms Drug Interactions

Want to check YOUR meds against Elderberry Plus Syrup?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
494Drugs
494 Moderate

Ingredients driving the most interactions

Reishi 375
Chaga 327
Black Elderberry Fruit Juice Concentrate 121

Individual Drug Interactions

The ingredients in Elderberry Plus Syrup interact with 494 drugs. Click any drug to see the details.

3 of the 6 ingredients in Elderberry Plus Syrup interact with drugs. Each result below shows which ingredient is responsible. Reishi Chaga Black Elderberry Fruit Juice Concentrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Elderberry Plus Syrup with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Reishi3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.

Likelihood Possible Evidence D
Reishi full monograph & interactions

Chaga3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that chaga extract can inhibit platelet aggregation. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that chaga might decrease blood glucose levels and increase insulin levels. This has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, chaga might interfere with immunosuppressive therapy.
In vitro research suggests that certain constituents of chaga stimulate immune function. This has not been reported in humans.

Likelihood Possible Evidence D
Chaga full monograph & interactions

Black Elderberry Fruit Juice Concentrate2 drug types · 121 drugs

Immunosuppressants

Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.

Likelihood Possible Evidence B
Pazopanib (Votrient)

Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 4 weeks for soft-tissue sarcoma developed severe nausea, loose stools, and elevated alanine transaminase and aspartate transaminase levels and was diagnosed with grade 3 liver injury. The patient reported taking elderberry supplements for 2 years, dose unspecified, and was also taking a multivitamin and a calcium supplement. The patient's symptoms and liver enzyme levels improved upon discontinuation of pazopanib and all supplements. Pazopanib treatment was re-initiated, at a lower dose, with no further evidence of liver injury. It was unclear in this case report if the elderberry supplements were derived from the berry, the flower, or the combination.

Likelihood Possible Evidence D
Black Elderberry Fruit Juice Concentrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Elderberry Plus Syrup, from the product label.

Host Defense Mushrooms

See all Host Defense Mushrooms products
Name
Fungi Perfecti, LLC
Street Address
PO Box 7634
City
Olympia
State
WA
ZipCode
98507
Phone Number
877-504-6926
Web Address
Hostdefense.com
Pharmacist Counseling Corner

Elderberry Plus Syrup by Host Defense Mushrooms: Common Questions

Does Elderberry Plus Syrup by Host Defense Mushrooms interact with any medications?
Yes. Based on its ingredients, Elderberry Plus Syrup has a known interaction with 494 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Elderberry Plus Syrup contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this actually help with colds or the flu?
The evidence we hold on elderberry for colds and respiratory infections is insufficient to say whether it works. Reishi and chaga show similar gaps for immune support. If you're hoping for proven cold relief, talk with your pharmacist about what the current research supports.
Can I take this if I'm pregnant or breastfeeding?
No. Chaga and reishi lack enough safety data—avoid them in pregnancy and while breastfeeding. Elderberry also doesn't have reliable safety information for these periods. Talk with your doctor or pharmacist before using any supplement during pregnancy or nursing.
What are the side effects I should watch for?
From reishi, you might see dizziness, dry mouth, itching, nausea, rash, or stomach upset. A few people have had respiratory allergies to reishi spores, causing sore throat or runny nose. Elderberry from ripe, cooked fruit is usually well tolerated, but raw or unripe berries can cause severe nausea, vomiting, or diarrhea.
Is it okay to use this long-term?
Reishi is generally well tolerated short-term, but we don't have good data on long-term safety. Chaga human safety data are limited. If you plan to use this regularly for months, check with your pharmacist first.
What does chaga do in this product?
Chaga is a medicinal mushroom added for its traditional use in immune support, but the evidence we hold doesn't confirm it works for specific conditions. It does carry some documented interactions with blood thinners, diabetes drugs, and immunosuppressants.
Why is there a caution about raw elderberries?
Raw or unripe elderberries, and the leaves, bark, and seeds, contain toxins that cause nausea, vomiting, severe diarrhea, and weakness. This syrup uses ripe, cooked fruit, which is safe—cooking destroys the toxin.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Elderberry Plus Syrup is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Elderberry Plus Syrup label
Go deeper

The Full Monographs Behind Elderberry Plus Syrup’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chaga

Interacts with 327 drugs

Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for its benefits is very limited, and it may...

Read the full Chaga monograph → Herb & supplement monograph

Reishi Mushroom

Interacts with 375 drugs

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...

Read the full Reishi Mushroom monograph → Herb & supplement monograph

Elderberry

Interacts with 121 drugs

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu symptoms, but the evidence is limited and n...

Read the full Elderberry monograph →
Sources

Sources & How We Checked

Elderberry Plus Syrup's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 32 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chaga 9 references
  1. Sun JE, Ao ZH, Lu ZM, et al. Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. J Ethnopharmacol 2008;118(1):7-13. PubMed
  2. Hyun KW, Jeong SC, Lee DH, et al. Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus. Peptides 2006;27(6):1173-8. PubMed
  3. Kim YO, Han SB, Lee HW, et al. Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus. Life Sci 2005;77(19):2438-56. PubMed
  4. Kikuchi Y, Seta K, Ogawa Y, et al. Chaga mushroom-induced oxalate nephropathy. Clin Nephrol 2014;81(6):440-4. PubMed
  5. Lee S, Lee HY, Park Y, et al. Development of end stage renal disease after long-term ingestion of chaga mushroom: case report and review of literature. J Korean Med Sci. 2020;35(19):e122.
  6. Kwon O, Kim Y, Paek JH, et al. Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report. Medicine (Baltimore) 2022;101(10):e28997. PubMed
  7. Su L, Xin C, Yang J, et al. A polysaccharide from Inonotus obliquus ameliorates intestinal barrier dysfunction in mice with type 2 diabetes mellitus. Int J Biol Macromol 2022;214:312-323. PubMed
  8. Chen S, Ma Y, Li H, et al. Anti-diabetic e?ects of Inonotus obliquus extract in high fat diet combined streptozotocin-induced type 2 diabetic mice. Nutr Hosp 2022;39(6):1256-1263. PubMed
  9. Ye X, Wu K, Xu L, et al. Methanol extract of Inonotus obliquus improves type 2 diabetes mellitus through modifying intestinal flora. Front Endocrinol (Lausanne) 2023;13:1103972. PubMed

See these in context on the Chaga monograph →

Reishi Mushroom 17 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
  3. Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
  4. Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64. PubMed
  5. Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6. PubMed
  6. Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181.
  7. Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db
  8. Chu, T. T., Benzie, I. F., Lam, C. W., Fok, B. S., Lee, K. K., and Tomlinson, B. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br.J.Nutr. 2012;107(7):1017-1027.
  9. Jin, X., Ruiz, Beguerie J., Sze, D. M., and Chan, G. C. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane.Database.Syst.Rev. 2012;6:CD007731.
  10. Kabir, Y., Kimura, S., and Tamura, T. Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol.(Tokyo) 1988;34(4):433-438. PubMed
  11. Kanmatsuse, K., Kajiwara, N., Hayashi, K., Shimogaichi, S., Fukinbara, I., Ishikawa, H., and Tamura, T. [Studies on Ganoderma lucidum. I. Efficacy against hypertension and side effects]. Yakugaku Zasshi 1985;105(10):942-947. PubMed
  12. Gao, Y., Lan, J., Dai, X., Ye, J., and Zhou, S. A Phase I/II Study of Ling Zhi Mushroom Ganoderma lucidum(W.Curt: Fr.) Lloyd (Aphyllophoromycetideae) Extract in Patients with Type II Diabetes Mellitus. International Journal of Medicinal Mushrooms 2004;6. DOI
  13. Jin H, Zhang G, Cao X, and et al. Treatment of hypertension by linzhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Niimi H, Xiu RJ, Sawada T, and et al. Microcirculatory Approach to Asi
  14. Klupp NL, Chang D, Hawke F, Kiat H, Cao H, Grant SJ, Bensoussan A. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015 Feb 17;2:CD007259. PubMed
  15. Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:809614.
  16. Pazzi F, Adsuar JC, Domínguez-Muñoz FJ, García-Gordillo MA, Gusi N, Collado-Mateo D. Ganoderma lucidum effects on mood and health-related quality of life in women with fibromyalgia. Healthcare (Basel) 2020;8(4):520. PubMed
  17. Kogure T, Koiwai A, Fukushi D, et al. Hypereosinophilia with hepatic nodule formation caused by Ganoderma lucidum. Intern Med 2021;60(24):3897-3903.

See these in context on the Reishi Mushroom monograph →

Elderberry 6 references
  1. Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
  2. Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
  3. European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
  4. Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
  5. Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
  6. Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed

See these in context on the Elderberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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