Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Exequel Ingredients & Drug Interactions

by Quality Of Life

Exequel label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Exequel against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Exequel is a dietary supplement by Quality Of Life with 1 active ingredient. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are sterillized Lactobacillus acidophilus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Exequel by Quality Of Life

Ask about any prescription or over-the-counter medication and we check it for interactions with Exequel by Quality Of Life — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Exequel by Quality Of Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Exequel contains one active ingredient: sterile Lactobacillus acidophilus, a beneficial live bacterial strain that naturally lives in your digestive tract. The capsule also holds inactive ingredients — tapioca starch, vegetable cellulose, leucine, silica, and sodium citrate — which help hold the formula together and protect the live organisms.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lactobacillus Acidophilus's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Support healthy skin and soothe dry sensitive skin.
  • We looked for evidence on: Atopic dermatitis (eczema), Psoriasis, Skin irritation, Xerosis.
  • The closest evidence on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Atopic dermatitis (eczema) (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Psoriasis.

The evidence for L. acidophilus is mixed. It's rated possibly effective for irritable bowel syndrome (IBS), Helicobacter pylori (a stomach bacteria), antibiotic-associated diarrhea, and bacterial vaginosis.

It's rated possibly ineffective for atopic disease (eczema, allergies, asthma). For acute respiratory distress syndrome (ARDS), there isn't enough reliable evidence to know either way.

The evidence, ingredient by ingredient Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. However, the data are limited, so check with your doctor before you start, especially if you have a weakened immune system or a condition that affects your gut barrier.

Because these are live organisms, there is a small theoretical risk of serious infection in certain vulnerable patients — though this is rare. Some people experience mild digestive side effects like bloating, gas, stomach discomfort, or loose stools, but these are uncommon.

Rash and itching have been reported in rare cases, though it's unclear whether they were due to L. acidophilus itself or other factors. Pregnancy and breastfeeding safety data are not on file; talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lactobacillus Acidophilus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Exequel, double-check any antibiotic medications you're on. Antibiotics can reduce how well the probiotic works, so you'll want to space them out — your pharmacist can tell you exactly how far apart.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Exequel may help with irritable bowel syndrome, antibiotic-related diarrhea, and a couple of other digestive or infection-related concerns, though the evidence is modest. It's generally safe for healthy adults, but if you have a weakened immune system or take antibiotics, you need to time the doses carefully.

Check with your pharmacist before you start, especially if you have any serious health conditions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Exequel, straight from the product label.

Brand Quality Of Life
Barcode (UPC) 812259003523
Net contents 30 Vegicap(s)
Market status On market
Date entered into DSLD Apr 25, 2018
DSLD ID 175598
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Exequel by Quality Of Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
Servings per container
30
UPC/BARCODE
812259003523
IngredientAmount% DV
sterillized Lactobacillus acidophilus21 mg--

Other ingredients: Tapioca Starch, Vegetable Cellulose, Leucine, Silica, Sodium Citrate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Dry, prickly skin is more than just unattractive - it's also terribly uncomfortable.

Skin health

Soothes dry, sensitive skin Improves appearance of skin (21 mg)

Brand IP Statement(s)

While many common remedies have unpleasant side effects or just don't work, Exequel provides a safe, natural, and effective way to support healthy skin from the inside out.

L-92 is a trademark of Asahi Calpis Wellness Co. Ltd, Tokyo, Japan.

Formula

Produced from a patented, heat-sterilized, L. acidophilus probiotic, L-92 - the active ingredient in Exequel - has been clinically shown to: Soothe dry, sensitive skin. L-92 has been shown to soothe dry, temporarily irritated skin in placebo-controlled studies conducted on both adults and children. Improve appearance of skin. The same research showed L-92 helped promote smooth, clear skin. Exequel works by bringing chemical messengers of the immune system called cytokines into the right balance, thus promoting healthy skin.

Sterilized L. acidophilus (L-92)

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

V

GF

Non GMO

GMP

Formulation

Non GMO

This product is suitable for Vegetarians and gluten-free.

This product is suitable for Vegetarians and gluten-free.

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 vegicap daily with a meal.

Precautions

Warning: Do not use if seal is broken or missing.

Keep out of reach of children.

Consult your healthcare professional before use if you are pregnant or lactating, have or had a medical condition, or are taking prescription drugs.

Storage

Store at room temperature.

General

352.C.030.100

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Exequel by Quality Of Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Exequel label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Exequel by Quality Of Life

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Sterillized Lactobacillus acidophilus

Interacts with
182 drugs
21 mg per serving Form: L-92

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Sterillized Lactobacillus acidophilus monograph & interactions

Other (inactive) ingredients: Tapioca Starch, Vegetable Cellulose, Leucine, Silica, Sodium Citrate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Exequel by Quality Of Life Drug Interactions

Want to check YOUR meds against Exequel?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

sterillized Lactobacillus acidophilus 182

Individual Drug Interactions

The ingredients in Exequel interact with 182 drugs. Click any drug to see the details.

1 of the 1 ingredient in Exequel interact with drugs. Each result below shows which ingredient is responsible. sterillized Lactobacillus acidophilus

Each ingredient & the kinds of drugs it affects

For each ingredient in Exequel with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

sterillized Lactobacillus acidophilus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
sterillized Lactobacillus acidophilus full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Exequel, from the product label.

Quality Of Life

See all Quality Of Life products
Name
QOL Labs, LLC
City
Purchase
State
NY
ZipCode
10577
Phone Number
(914) 251-0981
Web Address
www.QOL.us
Pharmacist Counseling Corner

Exequel by Quality Of Life: Common Questions

Does Exequel by Quality Of Life interact with any medications?
Yes. Based on its ingredients, Exequel has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Exequel contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Do I have to avoid taking this with my antibiotics?
Not avoid — just separate them. Antibiotics can kill the live organisms in L. acidophilus, so taking them at the same time lowers how well the probiotic works. Ask your pharmacist how many hours to space them apart; usually a few hours does the trick.
Will this help my irritable bowel syndrome?
L. acidophilus is rated possibly effective for IBS, which means there's some evidence it may help, but it's not a sure thing. It's worth discussing with your doctor to see if it's worth trying for your situation.
Can I take this if I'm pregnant or breastfeeding?
We don't have safety data on file for pregnancy or breastfeeding with this ingredient. Talk with your doctor or pharmacist — they can help you decide whether it's right for you based on your personal health.
What are the main side effects?
Most people tolerate it well. Some experience mild digestive symptoms like bloating, gas, stomach discomfort, or loose stools, but these are uncommon. Rash and itching have been reported rarely, though it's unclear if they were caused by this ingredient.
Is there anything else I should know before I start?
If you have a weakened immune system or a condition affecting your gut barrier, check with your doctor first — there's a small theoretical risk of serious infection in vulnerable patients. Otherwise, it's generally safe for healthy adults and children.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Exequel is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Exequel label
Go deeper

The Full Monographs Behind Exequel’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph →
Sources

Sources & How We Checked

Exequel's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team