Extra Strength Ideal CBD 25 mg Natural Mint Ingredients & Drug Interactions
by Barlean's
What is this page for?
First and foremost: checking Extra Strength Ideal CBD 25 mg Natural Mint against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Extra Strength Ideal CBD 25 mg Natural Mint is a dietary supplement by Barlean's with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Full Spectrum Hemp Aerial Parts Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's
Ask about any prescription or over-the-counter medication and we check it for interactions with Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- “Full Spectrum Hemp Aerial Parts Extract” is listed as a grouped ingredient — the label gives one combined amount (35 mg) without saying how much of each component you get.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Extra Strength Ideal CBD 25 mg Natural Mint, straight from the product label.
| Brand | Barlean's |
|---|---|
| Net contents | 1.5 Fluid Ounce(s); 45 mL |
| Market status | On market |
| Date entered into DSLD | Jul 18, 2023 |
| DSLD ID | 291851 |
| Product type | Other Combinations |
| Supplement form | Liquid |
| Dietary claims / uses | Nutrient, All Other |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 10 Calorie(s) | -- |
| Total Fat | 1 Gram(s) | 1% |
| Saturated Fat | 1 Gram(s) | 4% |
| Cannabidiol | 25 mg | -- |
| Full Spectrum Hemp Aerial Parts Extract | 35 mg | -- |
Other ingredients: Medium Chain Triglyceride Oil, Full Spectrum Hemp Extract, natural Mint flavor
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions for use: Place 20 drops (approximately 3/4 full dropper) under the tongue as needed.
Precautions
Warning: Consult your physician before use.
Do not take if you are pregnant or nursing.
Keep out of reach of children.
Formulation
Product of U.S.A
Formula
Less than 0.3% THC
Hemp oil 1,125 mg CBD 25mg CBD per serving
General Statements
BPA and phthalate free bottle
Carpe CBDiem!
Barleans.com/Lookitup
Brand IP Statement(s)
Barlean's Estd 1989
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container45 Amounts shown are per serving.
Full Spectrum Hemp Aerial Parts Extract
Interacts with938 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Full Spectrum Hemp Aerial Parts Extract monograph & interactions- › Cannabidiol
Other (inactive) ingredients: Medium Chain Triglyceride Oil, Full Spectrum Hemp Extract, Natural Mint flavor. These complete the product’s ingredient list but are not active constituents.
Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's Drug Interactions
Extra Strength Ideal CBD 25 mg Natural Mint contains a single active ingredient, and it has known interactions with 938 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Extra Strength Ideal CBD 25 mg Natural Mint?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Extra Strength Ideal CBD 25 mg Natural Mint interact with 938 drugs. Click any drug to see the details.
1 of the 1 ingredient in Extra Strength Ideal CBD 25 mg Natural Mint interact with drugs. Each result below shows which ingredient is responsible. Full Spectrum Hemp Aerial Parts Extract
Belladonna Alkaloids, Ergotamine Tartrate, PhenobarbitalBel Tabs, Bellamine-S, Bellaphen-S, Duragal S, Phenarbal S, Spastrin
How Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interactionBelladonna, Caffeine, Ergotamine, PentobarbitalMicomp PB
How Belladonna, Caffeine, Ergotamine, Pentobarbital interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Belladonna, Caffeine, Ergotamine, Pentobarbital interactionBelladonna, Ergotamine Tartrate, Phenobarbital
How Belladonna, Ergotamine Tartrate, Phenobarbital interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Belladonna, Ergotamine Tartrate, Phenobarbital interactionBelladonna, Ergotamine, PhenobarbitalBellergal-S
How Belladonna, Ergotamine, Phenobarbital interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Belladonna, Ergotamine, Phenobarbital interactionBellafoline, Caffeine, Ergotamine Tartrate, PentobarbitalCafergot PB
How Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interactionBelumosudil MesylateRezurock
How Belumosudil Mesylate interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Belumosudil Mesylate interactionBenazeprilLotensin
How Benazepril interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractAce Inhibitors (aceis), Antihypertensive Drugs Minor
Interaction Summary
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Read the full Full Spectrum Hemp Aerial Parts Extract + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractAntihypertensive Drugs, Ace Inhibitors (aceis) Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Full Spectrum Hemp Aerial Parts Extract + Benazepril, Hydrochlorothiazide interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bendamustine Hydrochloride interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzhydrocodone, AcetaminophenApadaz
How Benzhydrocodone, Acetaminophen interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Benzhydrocodone, Acetaminophen interactionBenzthiazideExna
How Benzthiazide interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Full Spectrum Hemp Aerial Parts Extract + Benzthiazide interactionBepridilVascor
How Bepridil interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bepridil interactionBetaxololBetoptic, Kerlone
How Betaxolol interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Full Spectrum Hemp Aerial Parts Extract + Betaxolol interactionBetrixabanBevyxxa
How Betrixaban interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Full Spectrum Hemp Aerial Parts Extract + Betrixaban interactionBexaroteneTargretin
How Bexarotene interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bexarotene interactionBictegravir, Emtricitabine, Tenofovir AlafenamideBiktarvy
How Bictegravir, Emtricitabine, Tenofovir Alafenamide interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bictegravir, Emtricitabine, Tenofovir Alafenamide interactionBisoprololZebeta
How Bisoprolol interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bisoprolol interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bisoprolol, Hydrochlorothiazide interactionBivalirudinAngiomax, Angiomax Rtu, Angiox
How Bivalirudin interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bivalirudin interactionBoceprevirVictrelis
How Boceprevir interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Boceprevir interactionBosentanTracleer
How Bosentan interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bosentan interactionBosutinibBosulif
How Bosutinib interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bosutinib interactionBrentuximab VedotinAdcetris
How Brentuximab Vedotin interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Brentuximab Vedotin interactionBrexpiprazoleRexulti
How Brexpiprazole interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Brexpiprazole interactionBrigatinibAlunbrig
How Brigatinib interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Aerial Parts Extract + Brigatinib interactionBromfenac SodiumBromsite, Prolensa
How Bromfenac Sodium interacts with Extra Strength Ideal CBD 25 mg Natural Mint — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp Aerial Parts ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Full Spectrum Hemp Aerial Parts Extract + Bromfenac Sodium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Extra Strength Ideal CBD 25 mg Natural Mint with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Full Spectrum Hemp Aerial Parts Extract
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for Extra Strength Ideal CBD 25 mg Natural Mint, from the product label.
Barlean's
See all Barlean's products- Name
- Barlean's
- City
- Ferndale
- State
- WA
- ZipCode
- 98248
- Phone Number
- 800.445.3529
- Web Address
- barleans.com
Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's: Common Questions
Does Extra Strength Ideal CBD 25 mg Natural Mint by Barlean's interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Extra Strength Ideal CBD 25 mg Natural Mint is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Extra Strength Ideal CBD 25 mg Natural Mint’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Extra Strength Ideal CBD 25 mg Natural Mint's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC