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Dietary supplement

Eyebright Extract Ingredients & Drug Interactions

by BulkSupplements.com

Eyebright Extract label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Eyebright Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Eyebright Extract is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for eye irritation and redness, conjunctivitis (pink eye), eye strain.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Eyebright Aerial Part Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Eyebright Extract by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Eyebright Extract by BulkSupplements.com — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Eyebright Extract by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: eyebright aerial part extract — the above-ground portions of the eyebright plant in concentrated form. There are no other inactive ingredients listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Eyebright's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: eye health and comfort.
  • We looked for evidence on: Asthenopia (eye strain), Conjunctivitis, Allergic rhinitis (hay fever), eye irritation, eye redness, ocular discomfort.
  • The closest evidence on file: Eyebright is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Eyebright is rated "Insufficient Reliable Evidence To Rate" for Asthenopia (eye strain), Conjunctivitis.

The evidence for eyebright isn't established in the data we hold. For allergic rhinitis (hay fever), common cold, cough, pharyngitis, rhinosinusitis, and cancer, we have insufficient reliable evidence to rate how well it works.

If you're considering it for one of these uses, chat with your pharmacist about what the current research shows.

The evidence, ingredient by ingredient Eyebright

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, eyebright has been reported to cause confusion, headache, nausea, constipation, cough, trouble breathing, and nasal congestion. The safety data advises against use during pregnancy and while breastfeeding — not enough is known to say it's safe for either.

Also be cautious: using homemade or non-sterile eyebright preparations directly in the eye carries real risk, even though small amounts as a tea are likely okay.

Side effects, ingredient by ingredient Eyebright

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Eyebright.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes drug — whether insulin, metformin, sulfonylureas, or another class — check your exact medication here before starting eyebright. Your blood sugar could drop too far when the two are combined.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Eyebright is a single-ingredient extract with limited evidence for its intended uses. If you take diabetes medication, check with your pharmacist before adding it — there's a real risk of low blood sugar.

Pregnant or breastfeeding? Skip it until you've talked with your doctor or pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Eyebright Extract, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X001N1GYEH
Net contents 100 Gram(s); 3.5 Ounce(s)
Market status On market
Date entered into DSLD May 23, 2024
DSLD ID 312470
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Eyebright Extract by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 mg
Maximum serving Sizes:
500 mg
Servings per container
200
UPC/BARCODE
X001N1GYEH
IngredientAmount% DV
Eyebright Aerial Part Extract500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

BulkSupplements.com Clean & pure bulk supplements

Formulation

Color may vary

Free of: Added sugar, soy, dairy, yeast, gluten, additives

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 500 mg (about 1/5 tsp) once or twice daily, or as directed by a physician.

Storage

Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool place

General Statements

Use an accurate milligram scale. New

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Eyebright Extract by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Eyebright Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Eyebright Extract by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 mg Dosage formPowder Servings per container200 Amounts shown are per serving.

Eyebright Aerial Part Extract

Interacts with
86 drugs
500 mg per serving Form: Euphrasia officinalis Aerial Part Extract

Eyebright is a traditional herb long used for minor eye irritation, redness, and allergy symptoms, but high-quality human studies are very limited. Th...

Eyebright Aerial Part Extract monograph & interactions
Interaction report

Eyebright Extract by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Eyebright Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Eyebright Aerial Part Extract 86

Individual Drug Interactions

The ingredients in Eyebright Extract interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Eyebright Extract interact with drugs. Each result below shows which ingredient is responsible. Eyebright Aerial Part Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Eyebright Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Eyebright Aerial Part Extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that eyebright lowers blood glucose levels.

Likelihood Possible Evidence D
Eyebright Aerial Part Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Eyebright Extract, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Road
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Eyebright Extract by BulkSupplements.com: Common Questions

Does Eyebright Extract by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Eyebright Extract has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Eyebright Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this while I'm pregnant or breastfeeding?
No, the safety data advises against it in both cases. There isn't enough information to know whether it's safe, so it's best to avoid it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist for personalized advice.
What side effects might I notice if I take this by mouth?
Eyebright has been reported to cause confusion, headache, nausea, constipation, cough, trouble breathing, and nasal congestion when taken orally. Most people tolerate small amounts as a tea, but these effects have been documented.
Can I put this directly in my eyes?
No — using homemade or non-sterile eyebright preparations in the eye is risky. Stick to taking it by mouth in the form of a tea or supplement, not as an eye drop or rinse.
Does eyebright actually work for hay fever or colds?
We don't have enough reliable evidence to say whether it works for allergic rhinitis, common cold, cough, sore throat, or sinus issues. The evidence just isn't there yet.
Why do I need to be careful if I take diabetes medication?
Animal research shows eyebright lowers blood glucose, which means it could add to the effect of your diabetes drug and make your blood sugar drop too low. That's a moderate-level concern worth checking with your pharmacist about.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Eyebright Extract is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Eyebright Extract label
Go deeper

The Full Monographs Behind Eyebright Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Eyebright

Interacts with 86 drugs

Eyebright is a traditional herb long used for minor eye irritation, redness, and allergy symptoms, but high-quality human studies are very limited. There is not enough reliable evidence to c...

Read the full Eyebright monograph →
Sources

Sources & How We Checked

Eyebright Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eyebright 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  3. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  4. Porchezhian, E., Ansari, S. H., and Shreedharan, N. K. Antihyperglycemic activity of Euphrasia officinale leaves. Fitoterapia 2000;71(5):522-526. PubMed

See these in context on the Eyebright monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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