Fenugreek Ingredients & Drug Interactions
by Herb Pharm
What is this page for?
First and foremost: checking Fenugreek against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Fenugreek is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for blood sugar control, boosting breast milk supply, high cholesterol.Based on those ingredients, 389 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fenugreek seed (Trigonella foenum-graecum) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Fenugreek by Herb Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Fenugreek by Herb Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Fenugreek by Herb Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: fenugreek seed extract from Trigonella foenum-graecum. The extract is prepared in certified organic cane alcohol and distilled water.
Does it work?
Moderate evidence
Fenugreek seed is rated possibly effective for sexual dysfunction and possibly effective for dysmenorrhea (severe menstrual cramping). It's also rated possibly effective for type 2 diabetes.
The evidence supporting these uses comes from clinical research, though the body of data for each indication is still being built out. If you're considering it for one of these purposes, talk with your doctor or pharmacist about what the current evidence shows and whether it's the right choice for you.
How safe is it?
Well-documented data
Fenugreek seed is generally well tolerated in food amounts, but supplement doses can cause side effects. The most common are abdominal pain, bloating, diarrhea, indigestion, gas, and nausea.
Rare but serious allergic reactions — including throat swelling, bronchospasm, and shock — have occurred. If you notice facial swelling, wheezing, or trouble breathing, stop and seek emergency care.
Do not use medicinal amounts during pregnancy; animal and human evidence suggest fenugreek may affect the uterus. Fenugreek is often promoted to boost milk supply and is rated possibly safe during breastfeeding, but evidence is limited — talk with your provider first.
One more thing: fenugreek can cause an unusual body odor in newborns whose mothers took it near delivery; this odor typically resolves on its own.
Meds to double-check
Moderate interaction found
Check before using if you take blood thinners (anticoagulants) or antiplatelet drugs like warfarin, clopidogrel, or aspirin; diabetes medications; theophylline, phenytoin (Dilantin), or sildenafil (Viagra); or blood pressure drugs like metoprolol. These are the main medication types fenugreek may interact with at a Moderate severity level.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Fenugreek extract may be worth considering if you're interested in support for blood sugar, menstrual discomfort, or sexual function — though the evidence is still limited. It's not a good fit if you take blood thinners, diabetes medications, or certain heart and seizure drugs without checking first.
Pregnant people should avoid it. Before adding this to your routine, talk it over with your own doctor or pharmacist to make sure it won't clash with your medications or health situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Fenugreek, straight from the product label.
| Brand | Herb Pharm |
|---|---|
| Barcode (UPC) | 090700000547 |
| Net contents | 1 fl. Oz.; 30 mL |
| Market status | On market |
| Date entered into DSLD | Apr 25, 2019 |
| DSLD ID | 200933 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Fenugreek by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Fenugreek seed (Trigonella foenum-graecum) extract | 614 mg | -- |
Other ingredients: certified organic Cane Alcohol, distilled Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use Shake well before using Add 1 full squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 5 times per day. Best taken between meals.
Precautions
Caution: Seek expert medical advice before taking during pregnancy.
Keep out of the reach of children
Storage
Store away from heat & light
General
011
Formula
Trigonella foenum-graecum
Fenugreek Liquid Extract
Prepared from the seed of certified organically grown Trigonella foenum-graecum plants.
General Statements
System restoration Reproductive
Dry herb/menstruum ratio: 1:2.5
Seals/Symbols
USDA Organic
FDA Statement of Identity
Herbal Supplement
Formulation
Gluten-Free
Certified organic by Organic Certifiers
FDA Disclaimer Statement
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Fenugreek by Herb Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Fenugreek by Herb Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container42 Amounts shown are per serving.
Fenugreek seed (Trigonella foenum-graecum) extract
Interacts with389 drugs
Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. So...
Fenugreek seed (Trigonella foenum-graecum) extract monograph & interactionsOther (inactive) ingredients: Certified organic Cane Alcohol, Distilled Water. These complete the product’s ingredient list but are not active constituents.
Fenugreek by Herb Pharm Drug Interactions
HelloPharmacist Interaction Report
Herb Pharm's Fenugreek extract can interact with a number of common medications through its fenugreek seed content.
The most serious concern involves blood thinners (anticoagulants) and antiplatelet drugs — fenugreek may add to their effects, raising the risk of bleeding. This includes warfarin (Coumadin) and clopidogrel (Plavix), as well as other anticoagulants and antiplatelet medications.
Read the full breakdown — every affected drug type, severity by severity
Fenugreek can also lower blood sugar (glucose) levels and may amplify the effect of diabetes medications, potentially causing low blood sugar. It may reduce how well theophylline, phenytoin (Dilantin), and sildenafil (Viagra) work in your body, and it could add to the blood-pressure-lowering effects of metoprolol (Toprol) and similar drugs.
Altogether, these interactions span 389 individual medications.
If you're on any prescription medication — especially blood thinners, diabetes drugs, seizure medications, heart or blood pressure drugs, or asthma treatments — run it through the checker below before starting this product. Your doctor or pharmacist can tell you whether it's safe to combine.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Fenugreek?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Fenugreek interact with 389 drugs. Click any drug to see the details.
1 of the 1 ingredient in Fenugreek interact with drugs. Each result below shows which ingredient is responsible. Fenugreek seed (Trigonella foenum-graecum) extract
AcebutololRhotral, Sectral
How Acebutolol interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Ammonium Chloride interactionAprocitentanTryvio
How Aprocitentan interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Aprocitentan interactionAtenololAtenix, Tenormin
How Atenolol interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Atenolol, Chlorthalidone interactionAzilsartanEdarbi
How Azilsartan interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Azilsartan, Chlorthalidone interactionBenazeprilLotensin
How Benazepril interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Benzthiazide interactionBetaxololBetoptic, Kerlone
How Betaxolol interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Betaxolol interactionBisoprololZebeta
How Bisoprolol interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Bisoprolol interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Bisoprolol, Hydrochlorothiazide interactionBosentanTracleer
How Bosentan interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Bosentan interactionBumetanideBurinex
How Bumetanide interacts with Fenugreek — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed (trigonella Foenum-graecum) ExtractAntihypertensive Drugs Minor
Interaction Summary
Fenugreek may also have an additive effect on blood pressure-lowering medications.
Read the full Fenugreek Seed (trigonella Foenum-graecum) Extract + Bumetanide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Fenugreek with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Fenugreek seed (Trigonella foenum-graecum) extract
Anticoagulant/Antiplatelet Drugs
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Some of the constituents in fenugreek have antiplatelet effects in animal and in vitro research. However, common fenugreek products might not contain sufficient concentrations of these constituents for clinical effects. A clinical study in patients with coronary artery disease or diabetes shows that taking fenugreek seed powder 2.5 grams twice daily for 3 months does not affect platelet aggregation, fibrinolytic activity, or fibrinogen levels .
Antidiabetes Drugs
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Clinical research shows that fenugreek seed can reduce fasting blood glucose and 2-hour postprandial glucose levels in adults with type 2 diabetes.
Clopidogrel (Plavix)
Theoretically, fenugreek seed might alter the clinical effects of clopidogrel by inhibiting its conversion to the active form.
Animal research shows that fenugreek seed 200 mg/kg daily for 14 days increases the maximum serum concentration of clopidogrel by 21%. It is unclear how this affects the pharmacokinetics of the active metabolite of clopidogrel; however, this study found that concomitant use of fenugreek seed and clopidogrel prolonged bleeding time by an additional 11%.
Metoprolol (Toprol)
Theoretically, fenugreek seed might have additive hypotensive effects when used with metoprolol.
Animal research shows that fenugreek seed 300 mg/kg daily for 2 weeks decreases systolic and diastolic blood pressure by 9% and 11%, respectively, when administered alone, and by 15% and 22%, respectively, when given with metoprolol 10 mg/kg.
Phenytoin (Dilantin)
Theoretically, fenugreek might decrease plasma levels of phenytoin.
Animal research shows that taking fenugreek seeds for 1 week decreases maximum concentrations and the area under the curve of a single dose of phenytoin by 44% and 72%, respectively. This seems to be related to increased clearance. So far, this interaction has not been reported in humans.
Sildenafil (Viagra)
Theoretically, concurrent use of sildenafil and fenugreek might reduce levels and therapeutic effects of sildenafil.
Animal research shows that taking fenugreek seeds for 1 week reduces maximum concentrations and the area under the curve of a single dose of sildenafil by 27% and 48%, respectively. So far, this interaction has not been reported in humans.
Theophylline
Theoretically, fenugreek may reduce the levels and clinical effects of theophylline.
Animal research shows that fenugreek 50 grams daily for 7 days reduces the maximum serum concentration (Cmax) of theophylline by 28% and the area under the plasma drug concentration-time curve (AUC) by 22%.
Warfarin (Coumadin)
Theoretically, fenugreek might have additive effects with warfarin and increase the international normalized ratio (INR).
Some fenugreek constituents have antiplatelet effects, although these might not be present in concentrations that are clinically significant. In one case report, a patient taking warfarin experienced an increased INR when starting to take fenugreek in combination with boldo.
Antihypertensive Drugs
Fenugreek may also have an additive effect on blood pressure-lowering medications. Studies on animals have shown that fenugreek seed can decrease both systolic and diastolic blood pressure by up to 22% when combined with metoprolol. Therefore, it is essential to monitor your blood pressure regularly if you are taking fenugreek and metoprolol together or any other antihypertensive drugs.
Brand information
Manufacturer and brand details for Fenugreek, from the product label.
Herb Pharm
See all Herb Pharm products- Name
- Herb Pharm
- City
- Williams
- State
- OR
- ZipCode
- 97544
- Phone Number
- 800-348-4372
- Web Address
- www.herb-pharm.com
Fenugreek by Herb Pharm: Common Questions
Does Fenugreek by Herb Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I use fenugreek if I'm pregnant?
Is fenugreek safe to use while breastfeeding?
What are the common side effects?
Does fenugreek actually help with blood sugar?
Will fenugreek change how my blood thinner works?
Why does fenugreek sometimes cause a body odor?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Fenugreek is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Fenugreek’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Fenugreek's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fenugreek 30 references
- Madar Z, Thorne R. Dietary fiber. Prog Food Nutr Sci 1987;11:153-74.
- Sharma RD, Raghuram TC, Rao NS. Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur J Clin Nutr 1990;44:301-6.
- Patil SP, Niphadkar PV, Bapat MM. Allergy to fenugreek (Trigonella foenum graecum). Ann Allergy Asthma Immunol 1997;78:297-300. PubMed
- Lambert J, Cormier J. Potential interaction between warfarin and boldo-fenugreek. Pharmacotherapy 2001;21:509-12. PubMed
- Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. Prostaglandins Leukot Essent Fatty PubMed
- Yalcin SS, Tekinalp G, Ozalp I. Peculiar odor of traditional food and maple syrup urine disease. Pediatr Int 1999;41:108-9. PubMed
- Sewell AC, Mosandl A, Bohles H. False diagnosis of maple syrup urine disease owing to ingestion of herbal tea. N Engl J Med 1999;341:769.. PubMed
- Abdo MS, al-Kafawi AA. Experimental studies on the effect of Trigonella foenum-graecum (abstract). Planta Med 1969;17:14-8.
- Gupta A, Gupta R, Lal B. Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double blind placebo controlled study. J Assoc Physicians India 2001;49:1057-61.
- Gabay MP. Galactogogues: medications that induce lactation. J Hum Lact 2002;18:274-9. PubMed
- Chevassus H, Gaillard JB, Farret A, et al. A fenugreek seed extract selectively reduces spontaneous fat intake in overweight subjects. Eur J Clin Pharmacol 2010;66(5):449-55. PubMed
- Turkyilmaz C, Onal E, Hirfanoglu IM, et al. The effect of galactagogue herbal tea on breast milk production and short-term catch-up of birth weight in the first week of life. J Altern Complement Med 2011;17(2):139-42. PubMed
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