Gentle Birth Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Gentle Birth against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Gentle Birth is a dietary supplement by Mountain Meadow Herbs with 10 active ingredients. Its ingredients are commonly taken for inducing labor or starting menstruation, menstrual cramps and irregular periods, symptoms of menopause.Based on those ingredients, 1,275 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ginger, False Unicorn, Blue Cohosh. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Gentle Birth by Mountain Meadow Herbs
Ask about any prescription or over-the-counter medication and we check it for interactions with Gentle Birth by Mountain Meadow Herbs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Gentle Birth by Mountain Meadow Herbs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Gentle Birth contains 10 active ingredients in a liquid form preserved with grain alcohol. The blend includes blue cohosh, wild yam, skullcap, blessed thistle, motherwort, bayberry, partridge berry, false unicorn, ginger, and red raspberry—traditionally used to support the birthing process.
The product also contains glycerin and distilled water as inactive ingredients.
Does it work?
Moderate evidence
The product facts do not include effectiveness ratings for most of these ingredients as they relate to birth support. Ginger is rated possibly effective for pregnancy-induced nausea and vomiting, and red raspberry leaf has insufficient evidence to rate its effectiveness for pregnancy-related uses.
For the other ingredients, evidence is either insufficient to establish effectiveness or not included in the data we hold. Talk to your healthcare provider about whether this product is appropriate for your needs.
How safe is it?
Well-documented data
Several ingredients in this product carry serious pregnancy warnings. Blue cohosh is rated likely unsafe in pregnancy and has been linked to heart problems in newborns.
False unicorn, motherwort, and blessed thistle are all rated likely unsafe in pregnancy. Wild yam and bayberry are rated possibly unsafe, and red raspberry leaf safety in pregnancy is not well established — use only with provider guidance.
For breastfeeding, safety information is either insufficient or advises against use for most ingredients. Blue cohosh can cause chest pain, high blood pressure, and high blood sugar in the person taking it, and ginger at high doses (above 5 grams daily) increases side effects including heartburn and diarrhea.
Meds to double-check
Moderate interaction found
Before taking Gentle Birth, check with your pharmacist or doctor if you take any of these: blood pressure medications (antihypertensives), diabetes medications, blood thinners (anticoagulants or antiplatelets including warfarin), heart medications (especially calcium channel blockers like nifedipine or diltiazem), lithium, insulin, cancer medications, sedating drugs, or estrogen therapy. Blue cohosh raises blood pressure and blood sugar; ginger and red raspberry increase bleeding risk; and false unicorn may increase blood levels of certain psychiatric and heart drugs.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is marketed for birthing support but carries significant medication interactions and serious pregnancy safety concerns. Do not use it without explicit guidance from your healthcare provider — especially if you're pregnant, breastfeeding, or taking any prescription medications for heart, blood sugar, blood clotting, or mental health.
Check your exact medications with our tool before considering this product.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 9 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Gentle Birth, straight from the product label.
| Brand | Mountain Meadow Herbs |
|---|---|
| Barcode (UPC) | 813086010111 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Apr 24, 2025 |
| DSLD ID | 327842 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Pregnant Women, Lactating, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Gentle Birth by Mountain Meadow Herbs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 1.25 mL | -- |
| Blue Cohosh | 0 NP | -- |
| Wild Yam | 0 NP | -- |
| Skullcap | 0 NP | -- |
| Blessed Thistle | 0 NP | -- |
| Motherwort | 0 NP | -- |
| Bayberry | 0 NP | -- |
| Partridge Berry | 0 NP | -- |
| False Unicorn | 0 NP | -- |
| Ginger | 0 NP | -- |
| Red Raspberry | 0 NP | -- |
Other ingredients: Glycerin, Water, Distilled, Grain Alcohol
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Childbirth support
GF (Gluten Free)
Vegan
Help your body prepare for childbirth Experience a comfortable labor and delivery Support a quick recovery
Formula
Expecting & nursing moms
FDA Statement of Identity
Herbal Dietary Supplement
General Statements
1 dropperful = approx. 1/8 tsp.
Midwife-favorite
The MMH Three-Leaf Promise: Our high-standards produce nothing less than pure, safe, and effective herbal products. You will always feel that we care - through our products, our service, and our understanding. We deliver on time.
Precautions
Caution: Do not use with products containing herbs already in this formula. Use with caution in cases of high or low blood pressure.
Caution: If you are pregnant, nursing, have a medical condition, or are taking a prescription, consult your health care provider before before using this product.
Keep out of reach of children.
Seals/Symbols
Made in Montana USA
Suggested/Recommended/Usage/Directions
Suggested use: During the last 5 weeks of pregnancy: Week 1: 1/4 tsp. 2 times daily before meals. Weeks 2-5: 1/4 tsp. 3 times daily before meals. Shake well.
Storage
Store in a cool, dry place out of sunlight.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Gentle Birth by Mountain Meadow Herbs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Gentle Birth by Mountain Meadow Herbs
These are the 10 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.25 tsp Dosage formLiquid Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Blue Cohosh
- › Wild Yam
- › Skullcap
- › Blessed Thistle
- › Motherwort
- › Bayberry
- › Partridge Berry
- › False Unicorn
- › Ginger
- › Red Raspberry
Other (inactive) ingredients: Glycerin, Water, Distilled, Grain Alcohol. These complete the product’s ingredient list but are not active constituents.
Gentle Birth by Mountain Meadow Herbs Drug Interactions
HelloPharmacist Interaction Report
Gentle Birth by Mountain Meadow Herbs is a 10-ingredient herbal liquid with several documented interactions with medications.
The most serious concern is blue cohosh, which can increase blood pressure through coronary vasoconstriction and may reduce the effectiveness of blood pressure drugs (antihypertensives) — a Moderate severity interaction. Blue cohosh also raises blood sugar levels and may decrease the effectiveness of diabetes medications (a Moderate concern), and it can amplify the effects of nicotine.
Read the full breakdown — every affected drug type, severity by severity
Other ingredients bring additional Moderate-severity interactions. False unicorn may increase blood levels of certain heart medications and psychiatric drugs by inhibiting liver enzymes (CYP2D6 and CYP3A4 substrates), and it may raise lithium levels, requiring dose adjustment.
Ginger interacts with blood thinners (anticoagulants and antiplatelets), diabetes medications, and several blood pressure drugs; it also affects how the liver processes certain cancer and other medications. Red raspberry leaf may increase bleeding risk with blood thinners and could lower blood sugar in people taking insulin.
Skullcap and motherwort both carry Moderate interactions with sedating drugs (CNS depressants) and may add to drowsiness or cognitive effects. Wild yam may interfere with estrogen therapy.
Blessed thistle has Minor interactions with acid-reflux medications (H2-blockers, antacids, and PPIs).
Partridge berry could not be checked — we hold no data for it. Before starting Gentle Birth, use the medication checker on this page to verify your exact drugs against these interactions.
Altogether, these interactions span 1,260 individual medications.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Gentle Birth?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Gentle Birth interact with 1,275 drugs. Click any drug to see the details.
8 of the 10 ingredients in Gentle Birth interact with drugs. Each result below shows which ingredient is responsible. Ginger False Unicorn Blue Cohosh Skullcap Motherwort Red Raspberry Wild Yam Blessed Thistle
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Ado-trastuzumab Emtansine interactionGingerCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
Red RaspberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Read the full Red Raspberry + Abciximab interactionGingerAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Ginger + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
GingerCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Abemaciclib interactionFalse UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Abiraterone interactionGingerCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
GingerCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Abiraterone Acetate interactionFalse UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
Red RaspberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Read the full Red Raspberry + Abrocitinib interactionGingerCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP2C9 substrates.
Read the full Ginger + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acalabrutinib interactionGingerP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase the absorption and blood levels of P-glycoprotein (P-gp) substrates.
Read the full Ginger + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
GingerAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Ginger + Acarbose interactionBlue CohoshAntidiabetes Drugs Moderate
Interaction Summary
There is some concern that blue cohosh might increase blood glucose levels.
Read the full Blue Cohosh + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Gentle Birth — through 1 ingredient. Tap an ingredient for the detail:
Blue CohoshAntihypertensive Drugs Moderate
Interaction Summary
Constituents in blue cohosh might increase blood pressure by causing coronary vasoconstriction.
Read the full Blue Cohosh + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
Red RaspberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Read the full Red Raspberry + Acenocoumarol interactionGingerAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Ginger + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
MotherwortCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort + Acepromazine interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acepromazine interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
GingerCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Aspirin interactionRed RaspberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Read the full Red Raspberry + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Gentle Birth — through 3 ingredients. Tap an ingredient for the detail:
Red RaspberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Read the full Red Raspberry + Acetaminophen, Aspirin, Caffeine interactionGingerAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Ginger + Acetaminophen, Aspirin, Caffeine interactionFalse UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
GingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Butalbital, Caffeine interactionFalse UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Gentle Birth — through 4 ingredients. Tap an ingredient for the detail:
GingerCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Acetaminophen, Butalbital, Caffeine, Codeine interactionFalse UnicornCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Butalbital, Caffeine, Codeine interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Butalbital, Caffeine, Codeine interactionMotherwortCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Gentle Birth — through 4 ingredients. Tap an ingredient for the detail:
MotherwortCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort + Acetaminophen, Butalbital, Codeine interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Butalbital, Codeine interactionFalse UnicornCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Butalbital, Codeine interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Gentle Birth — through 4 ingredients. Tap an ingredient for the detail:
False UnicornCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Butalbital, Codeine Phosphate interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Butalbital, Codeine Phosphate interactionMotherwortCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort + Acetaminophen, Butalbital, Codeine Phosphate interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Gentle Birth — through 4 ingredients. Tap an ingredient for the detail:
MotherwortCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionFalse UnicornCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionGingerCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Gentle Birth — through 4 ingredients. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Caffeine, Codeine interactionMotherwortCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort + Acetaminophen, Caffeine, Codeine interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Caffeine, Codeine interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Gentle Birth — through 4 ingredients. Tap an ingredient for the detail:
GingerCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Acetaminophen, Caffeine, Codeine, Salicylamide interactionFalse UnicornCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Caffeine, Codeine, Salicylamide interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Caffeine, Codeine, Salicylamide interactionMotherwortCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Gentle Birth — through 4 ingredients. Tap an ingredient for the detail:
MotherwortCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort + Acetaminophen, Caffeine, Dihydrocodeine interactionFalse UnicornCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Caffeine, Dihydrocodeine interactionGingerCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Acetaminophen, Caffeine, Dihydrocodeine interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Caffeine, Isometheptene interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
GingerCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Acetaminophen, Caffeine, Pyrilamine interactionFalse UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
False UnicornCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionGingerCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Gentle Birth — through 4 ingredients. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionMotherwortCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionSkullcapCns Depressants Moderate
Interaction Summary
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Read the full Skullcap + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
False UnicornCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
GingerCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionFalse UnicornCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionGingerCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
GingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionFalse UnicornCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Gentle Birth — through 2 ingredients. Tap an ingredient for the detail:
GingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionFalse UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Gentle Birth with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Ginger
Anticoagulant/Antiplatelet Drugs
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs. However, research is conflicting.
Laboratory research suggests that ginger inhibits thromboxane synthetase and decreases platelet aggregation. However, this has not been demonstrated unequivocally in humans, with mixed results from clinical trials. Theoretically, excessive amounts of ginger might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Antidiabetes Drugs
Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Animal and human research suggests that ginger might increase insulin levels and/or decrease blood glucose levels.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Ginger might increase or decrease the levels of CYP3A4 substrates.
In vitro research and some case reports suggest that ginger inhibits CYP3A4 activity. Three case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are CYP3A4 substrates (imatinib, dabrafenib, and crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.
Conversely, other in vitro research suggests that ginger induces CYP3A4 activity, leading to reduced levels of CYP3A4 substrates. However, this interaction has not been reported in humans.
Losartan (Cozaar)
Theoretically, ginger might increase levels of losartan and the risk of hypotension.
In animal research, ginger increased the levels and hypotensive effects of a single dose of losartan. It is not clear if ginger alters the concentration or effects of losartan when taken continuously. Additionally, this interaction has not been shown in humans.
Nifedipine (Procardia)
Ginger may have antiplatelet effects and increase the risk of bleeding if used with nifedipine.
Clinical research shows that combined treatment with ginger 1 gram plus nifedipine 10 mg significantly inhibits platelet aggregation when compared to nifedipine or ginger alone.
P-Glycoprotein Substrates
Ginger might increase the absorption and blood levels of P-glycoprotein (P-gp) substrates.
In vitro research and case reports suggest that ginger inhibits drug efflux by P-gp, potentially increasing absorption and serum levels of P-gp substrates. Two case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are P-gp substrates (trametinib, crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.
Phenprocoumon (Marcoumar, Others)
Ginger might increase the risk of bleeding with phenprocoumon.
Phenprocoumon, a warfarin-related anticoagulant, might increase the international normalized ratio (INR) when taken with ginger. There is one case report of a 76-year-old woman with a stable INR on phenprocoumon that increased to greater than 10 when she began consuming dried ginger and ginger tea.
Warfarin (Coumadin)
Ginger might increase the risk of bleeding with warfarin.
Laboratory research suggests that ginger might inhibit thromboxane synthetase and decrease platelet aggregation. In one case report, ginger increased the INR when taken with phenprocoumon, which has similar pharmacological effects as warfarin. In another case report, ginger increased the INR when taken with a combination of warfarin, hydrochlorothiazide, and acetaminophen. A longitudinal analysis suggests that taking ginger increases the risk of bleeding in patients taking warfarin for at least 4 months. However, research in healthy people suggests that ginger has no effect on INR, or the pharmacokinetics or pharmacodynamics of warfarin. Until more is known, monitor INRs closely in patients taking large amounts of ginger.
Calcium Channel Blockers
Theoretically, taking ginger with calcium channel blockers might increase the risk of hypotension.
Some animal and in vitro research suggests that ginger has hypotensive and calcium channel-blocking effects. Another animal study shows that concomitant administration of ginger and the calcium channel blocker amlodipine leads to greater reductions in blood pressure when compared with amlodipine alone.
Cyclosporine (Neoral, Sandimmune)
Theoretically, when taken prior to cyclosporine, ginger might decrease cyclosporine levels.
In an animal model, ginger juice taken 2 hours prior to cyclosporine administration reduced the maximum concentration and area under the curve of cyclosporine by 51% and 40%, respectively. This effect was not observed when ginger juice and cyclosporine were administered at the same time.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, ginger might increase the levels of CYP1A2 substrates.
In vitro research shows that ginger inhibits CYP1A2 activity. However, this interaction has not been reported in humans.
Cytochrome P450 2B6 (Cyp2B6) Substrates
Theoretically, ginger might increase the levels of CYP2B6 substrates.
In vitro research shows that ginger inhibits CYP2B6 activity. However, this interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, ginger might increase the levels of CYP2C9 substrates.
In vitro research shows that ginger inhibits CYP2C9 activity. However, this interaction has not been reported in humans.
Metronidazole (Flagyl)
Theoretically, ginger might increase levels of metronidazole.
In an animal model, ginger increased the absorption and plasma half-life of metronidazole. In addition, the elimination rate and clearance of metronidazole was significantly reduced.
False Unicorn
Cytochrome P450 2D6 (Cyp2D6) Substrates
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity. Theoretically, false unicorn might increase the levels of CYP2D6 substrates. Some of drugs that are CYP2D6 substrates include amitriptyline (Elavil), clozapine (Clozaril), codeine, desipramine (Norpramin), donepezil (Aricept), fentanyl (Duragesic), flecainide (Tambocor), fluoxetine (Prozac), meperidine (Demerol), methadone (Dolophine), metoprolol (Lopressor, Toprol XL), olanzapine (Zyprexa), ondansetron (Zofran), tramadol (Ultram), trazodone (Desyrel), and others.
Cytochrome P450 3A4 (Cyp3A4) Substrates
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity. Theoretically, false unicorn might increase the levels of CYP3A4 substrates. Drugs that might be affected include some calcium channel blockers (diltiazem, nicardipine, verapamil), chemotherapeutic agents (etoposide, paclitaxel, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), glucocorticoids, cisapride (Propulsid), alfentanil (Alfenta), fentanyl (Sublimaze), losartan (Cozaar), fluoxetine (Prozac), midazolam (Versed), omeprazole (Prilosec), ondansetron (Zofran), propranolol (Inderal), fexofenadine (Allegra), and numerous others.
Lithium
False unicorn is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, false unicorn might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Blue Cohosh
Antidiabetes Drugs
There is some concern that blue cohosh might increase blood glucose levels. Theoretically, it might decrease the effectiveness of medicines used for diabetes. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
Antihypertensive Drugs
Constituents in blue cohosh might increase blood pressure by causing coronary vasoconstriction. Theoretically, concomitant use might decrease the effectiveness of drugs used for angina and high blood pressure; use with caution. Some antihypertensive drugs include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.
Nicotine
Blue cohosh can increase the effects of nicotine.
Skullcap
Cns Depressants
Theoretically, skullcap can have additive effects when used with other CNS depressants.
Animal and clinical research suggests that skullcap can cause sedation and cognitive impairment.
Motherwort
Cns Depressants
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Motherwort has been reported to cause CNS depression and sedation.
Red Raspberry
Anticoagulant/Antiplatelet Drugs
Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
In vitro research suggests that red raspberry leaf extract has antiplatelet activity and enhances the in vitro effects of the antiplatelet medication cangrelor. This interaction has not been reported in humans.
Insulin
Red raspberry leaf might reduce glucose levels in patients being treated with insulin.
In one case report, a 38-year-old patient with gestational diabetes, whose blood glucose was being controlled with medical nutrition therapy and insulin, developed hypoglycemia after consuming two servings of raspberry leaf tea daily for 3 days beginning at 32 weeks' gestation. The patient required an insulin dose reduction. The hypoglycemia was considered to be probably related to use of red raspberry leaf tea.
Wild Yam
Estrogens
Theoretically, wild yam might increase or decrease the effects of estrogen.
Wild yam root shows estrogenic and anti-estrogenic effects in vitro. Theoretically, wild yam might interfere with hormone therapy.
Blessed Thistle
Antacids
Theoretically, blessed thistle might decrease the effectiveness of antacids.
There are reports that blessed thistle increases stomach acid.
H2-Blockers
Theoretically, blessed thistle might decrease the effectiveness of H2-blockers.
There are reports that blessed thistle increases stomach acid.
Proton Pump Inhibitors (Ppis)
Theoretically, blessed thistle might decrease the effectiveness of PPIs.
There are reports that blessed thistle increases stomach acid.
Brand information
Manufacturer and brand details for Gentle Birth, from the product label.
Mountain Meadow Herbs
See all Mountain Meadow Herbs products- Name
- Mountain Meadow Herbs, Inc.
- Street Address
- 1019 Hard Rock Rd
- City
- Somers
- State
- MT
- ZipCode
- 59932
- Phone Number
- 888.528.8615
- Web Address
- www.mmherbs.com
Gentle Birth by Mountain Meadow Herbs: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Gentle Birth is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Gentle Birth’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Blue Cohosh
Interacts with 259 drugsBlue cohosh is a traditional herb historically used by Native Americans and midwives to bring on labor or menstruation, but it carries serious safety concerns, especially for the heart and d...
Read the full Blue Cohosh monograph → Herb & supplement monographWild Yam
Interacts with 41 drugsWild yam is a root traditionally used for menopausal symptoms, cramps, and as a so-called 'natural' hormone supplement, but solid human evidence for these uses is lacking. Despite popular cl...
Read the full Wild Yam monograph → Herb & supplement monographSkullcap
Interacts with 248 drugsAmerican skullcap is an herb traditionally used to calm anxiety and promote relaxation, but solid human evidence is very limited. It is generally considered relatively safe for short-term us...
Read the full Skullcap monograph → Herb & supplement monographBlessed Thistle
Interacts with 36 drugsBlessed thistle is a bitter herb traditionally used to stimulate appetite and ease mild digestive complaints. High-quality human studies are lacking, so its benefits are not well proven. It...
Read the full Blessed Thistle monograph → Herb & supplement monographMotherwort
Interacts with 248 drugsMotherwort is a traditional herb in the mint family long used for anxiety, heart palpitations, and women's reproductive complaints, but solid human evidence is very limited. It should be avo...
Read the full Motherwort monograph → Herb & supplement monographBayberry
Bayberry is a traditional herb used mainly as an astringent for diarrhea, sore throats, and minor skin or gum problems, but there is very little modern human research to confirm it works. It...
Read the full Bayberry monograph → Herb & supplement monographFalse Unicorn
Interacts with 740 drugsFalse Unicorn is a North American plant whose root has long been used in traditional medicine for women's reproductive and menstrual concerns. There is very little reliable human research to...
Read the full False Unicorn monograph → Herb & supplement monographGinger
Interacts with 1,007 drugsGinger is a widely used culinary spice with a long history in traditional medicine, and it has the strongest evidence for helping with nausea and vomiting, including from motion sickness, pr...
Read the full Ginger monograph → Herb & supplement monographRed Raspberry
Interacts with 135 drugsRed raspberry leaf is a traditional herbal remedy most often used as a tea in late pregnancy and for menstrual discomfort, but solid scientific evidence for these uses is limited. It is gene...
Read the full Red Raspberry monograph →Sources & How We Checked
Gentle Birth's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 113 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Blue Cohosh 16 references
- Jones TK, Lawson BM. Profound neonatal congestive heart failure caused by maternal consumption of blue cohosh herbal medication. J Pediatr 1998;132:550-2. PubMed
- McFarlin BL, Gibson MH, O'Rear J, Harman P. A national survey of herbal preparation use by nurse-midwives for labor stimulation. Review of the literature and recommendations for practice. J Nurse Midwifery 1999;44:205-16. PubMed
- Wright IM. Neonatal effects of maternal consumption of blue cohosh. J Pediatr 1999;134:384-5. DOI
- Edmunds J. Blue cohosh and newborn myocardial infarction? Midwifery Today Int Midwife 1999;52:34-5.
- Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
- Irikura B, Kennelly E. American Health Consultants. Blue Cohosh: a word of caution. 1999. Available at: http://www.ahcmedia.com/articles/50424-blue-cohosh-a-word-of-caution.
- Gunn TR, Wright IM. The use of black and blue cohosh in labour. N Z Med J 1996;109:410-1.
- Baillie N, Rasmussen P. Black and blue cohosh in labour. N Z Med J 1997;110:20-1.
- Finkel RS, Zarlengo KM. Blue cohosh and perinatal stroke. N Engl J Med 2004;351:302-3. PubMed
- Kennelly, E. J., Flynn, T. J., Mazzola, E. P., Roach, J. A., McCloud, T. G., Danford, D. E., and Betz, J. M. Detecting potential teratogenic alkaloids from blue cohosh rhizomes using an in vitro rat embryo culture. J.Nat.Prod. 1999;62(10):1385-1389. PubMed
- Rao, R. B. and Hoffman, R. S. Nicotinic toxicity from tincture of blue cohosh (Caulophyllum thalictroides) used as an abortifacient. Vet.Hum.Toxicol. 2002;44(4):221-222.
- Gunn, T. R. and Wright, I. M. The use of black and blue cohosh in labour. N.Z Med J 10-25-1996;109(1032):410-411.
- Scott, C. C. and Chen, K. K. The pharmacological action of N-methylcytisine. The Journal of Pharmacology and Experimental Therapuetics 1943;79:334-339. DOI
- Low, D. T. Blue cohosh and neonatal myocardial toxicity. Journal of the American Herbalists Guild 2001;2(2):9-10.
- Dugoua JJ, Perri D, Seely D, et al. Safety and efficacy of blue cohosh (Caulophyllum thalictroides) during pregnancy and lactation. Can J Clin Pharmacol. 2008;15(1):e66-73.
- Sirtori CR, Triolo M, Bosisio R, et al. Hypocholesterolaemic effects of lupin protein and pea protein/fibre combinations in moderately hypercholesterolaemic individuals. Br J Nutr 2012;107:1176-83. PubMed
Wild Yam 7 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
- Cheong JL, Bucknall R. Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient. Postgrad Med J 2005;81:266-7.. PubMed
- Rosenberg Zand, R. S., Jenkins, D. J., and Diamandis, E. P. Effects of natural products and nutraceuticals on steroid hormone-regulated gene expression. Clin Chim.Acta 2001;312(1-2):213-219. PubMed
- Araghiniknam M, Chung S, Nelson-White T, and et al. Antioxidant activity of Dioscorea and dehydroepiandrosterone (DHEA) in older humans. Life Sciences 1996;59:L147-L157.
- Zeng M, Zhang L, Li M, et al. Estrogenic effects of the extracts from the Chinese Yam (Dioscorea opposite Thunb.) and its effective compounds in vitro and in vivo. Molecules. 2018 Jan 23;23(2). Pii: E11. PubMed
- Lu J, Wong RN, Zhang L, et al. Comparative analysis of proteins with stimulating activity on ovarian estradiol biosynthesis from four different Dioscorea species in vitro using both phenotypic and target-based approaches: implication for treating menopaus
Skullcap 3 references
- Wolfson P, Hoffmann DL. An investigation into the efficacy of Scutellaria lateriflora in healthy volunteers. Altern Ther Health Med 2003;9:74-8.
- Awad, R., Arnason, J. T., Trudeau, V., Bergeron, C., Budzinski, J. W., Foster, B. C., and Merali, Z. Phytochemical and biological analysis of skullcap (Scutellaria lateriflora L.): a medicinal plant with anxiolytic properties. Phytomedicine. 2003;10(8):6 PubMed
- Brock C, Whitehouse J, Tewfik I, Towell T. American skullcap (Scutellaria lateriflora): a randomised, double-blind placebo-controlled crossover study of its effects on mood in healthy volunteers. Phytother Res 2014;28(5):692-8.
Blessed Thistle 2 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Motherwort 6 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Wojtyniak K, Szymanski M, Matlawska I. Leonurus cardiaca L. (motherwort): a review of its phytochemistry and pharmacology. Phytother Res 2013;27(8):1115-20.
- Xia WT, Zhou H, Wang Y, et al. Motherwort injection in preventing post-abortion hemorrhage after induced abortion: A multi-center, prospective, randomized controlled trial. Explore (NY). 2019. pii: S1550-8307(19)30447-1. PubMed
- Cao Shan DOSOGC, Zhang W, Zhao Z, et al. Post-marketing safety surveillance and reevaluation of Motherwort injection: A clinical study of 10 094 cases. J Tradit Chin Med. 2018 Aug;38(4):625-635. DOI
Bayberry 3 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
False Unicorn 4 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Ho SH, Singh M, Holloway AC, Crankshaw DJ. The effects of commercial preparations of herbal supplements commonly used by women on the biotransformation of fluorogenic substrates by human cytochromes P450. Phytother Res. 2011;25(7):983-9. PubMed
Ginger 64 references
- Fischer-Rasmussen W, Kjaer SK, Dahl C, Asping U. Ginger treatment of hyperemesis gravidarum. Eur J Obstet Gynecol Reprod Biol 1991;38:19-24. PubMed
- Jewell D, Young G. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev 2000;(2):CD000145. PubMed
- Vutyavanich T, Kraisarin T, Ruangsri R. Ginger for nausea and vomiting in pregnancy: randomized, double-masked, placebo-controlled trial. Obstet Gynecol 2001;97:577-82. DOI
- Backon J. Ginger in preventing nausea and vomiting of pregnancy; a caveat due to its thromboxane synthetase activity and effect on testosterone binding. Eur J Obstet Gynecol Reprod Biol 1991;42:163-4. PubMed
- Srivastava KC. Effect of onion and ginger consumption on platelet thromboxane production in humans. Prostaglandins Leukot Essent Fatty Acids 1989;35:183-5. PubMed
- Stewart JJ, Wood MJ, Wood CD, Mims ME. Effects of ginger on motion sickness susceptibility and gastric function. Pharmacology 1991;42:111-20. PubMed
- Smith C, Crowther C, Willson K, et al. A randomized controlled trial of ginger to treat nausea and vomiting in pregnancy. Obstet Gynecol 2004;103:639-45. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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