Happy Drops Sweet Lemon Gummy Ingredients & Drug Interactions
by Organifi
What is this page for?
First and foremost: checking Happy Drops Sweet Lemon Gummy against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Happy Drops Sweet Lemon Gummy is a dietary supplement by Organifi with 4 active ingredients. Its ingredients are commonly taken for nausea and vomiting, motion sickness, morning sickness in pregnancy.Based on those ingredients, 1,361 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ginger Root Extract, Passionflower Aerial Extract, Gotu Kola Whole Herb Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Happy Drops Sweet Lemon Gummy by Organifi
Ask about any prescription or over-the-counter medication and we check it for interactions with Happy Drops Sweet Lemon Gummy by Organifi — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Happy Drops Sweet Lemon Gummy by Organifi
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Happy Drops Sweet Lemon Gummy contains four active ingredients: ginger root extract, gotu kola whole herb extract, passionflower aerial extract, and saffron (Saffr'Activ). The gummy is sweetened and flavored with cane sugar, tapioca syrup, pectin, citric acid, and natural flavors, with carnauba wax as a coating.
Does it work?
Moderate evidence
Ginger is possibly effective for pregnancy-related nausea and vomiting, period pain (dysmenorrhea), and osteoarthritis, but the evidence does not support it for exercise-related muscle soreness or chemotherapy-related nausea. Gotu kola is possibly effective for poor circulation in the legs (venous insufficiency) and burns, but not for radiation skin damage or memory and thinking.
Passionflower is possibly effective for insomnia and anxiety before medical procedures, but evidence is too limited to rate it for alcohol use disorder or withdrawal from benzodiazepines. Saffron (Saffr'Activ) is possibly effective for nerve damage from chemotherapy and Alzheimer's disease.
How safe is it?
Well-documented data
Ginger is generally well tolerated at typical food and supplement doses in healthy adults. At doses above 5 grams per day, side effects increase and tolerability drops.
Common mild side effects include stomach discomfort, burping, diarrhea, heartburn, and a peppery irritation of the mouth and throat. Gotu kola is generally well tolerated short-term, but liver concerns have been reported in at least four case reports, though causation is unclear.
The safety data is limited. Passionflower is generally well tolerated but commonly causes drowsiness, dizziness, and confusion.
A rare case of severe nausea, vomiting, and heart rhythm changes occurred after very high doses. Saffron is likely safe in food amounts, but at higher supplement doses the safety profile is less clear.
Common side effects include nausea, vomiting, and drowsiness; rare serious effects include allergic reactions. Ginger, gotu kola, passionflower, and saffron all lack sufficient safety data during pregnancy — traditional use advises against them.
Safety information during breastfeeding is also insufficient for all four ingredients.
Meds to double-check
Moderate interaction found
Check with your pharmacist if you take blood thinners or antiplatelet drugs (like warfarin, apixaban, or aspirin), blood pressure medications (especially calcium channel blockers like nifedipine or ARBs like losartan), diabetes medications, sedating or anti-anxiety drugs, liver-toxic medications, caffeine supplements, or medications processed through your liver's CYP3A4 pathway or P-glycoprotein transporters. If you're unsure whether your medications fall into these groups, use the interaction checker on this page with your exact drug names.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product may help with nausea, anxiety, insomnia, and certain types of pain or brain health, depending on which ingredient addresses your concern. If you take any blood thinners, blood pressure medications, diabetes medications, sedating drugs, or medications processed by your liver, talk to your pharmacist or doctor before starting this product — the interactions could affect how your drugs work or increase side effects.
The pregnancy and breastfeeding safety data is too limited; check with your doctor if you're pregnant, trying to become pregnant, or nursing.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Happy Drops Sweet Lemon Gummy, straight from the product label.
| Brand | Organifi |
|---|---|
| Barcode (UPC) | 850059332078 |
| Net contents | 60 Gummy(ies) |
| Market status | On market |
| Date entered into DSLD | Jan 23, 2025 |
| DSLD ID | 327926 |
| Product type | Botanical |
| Supplement form | Gummy Or Jelly |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Happy Drops Sweet Lemon Gummy by Organifi, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 20 Calorie(s) | -- |
| Total Carbohydrates | 5 Gram(s) | 2% |
| Added Sugars | 3 Gram(s) | 6% |
| Total Sugars | 3 Gram(s) | -- |
| Ginger Root Extract | 15 mg | -- |
| Gotu Kola Whole Herb Extract | 100 mg | -- |
| Passionflower Aerial Extract | 150 mg | -- |
| Saffr'Activ | 30 mg | -- |
Other ingredients: Cane Sugar, Tapioca Syrup, Water, Pectin, Flavors, Citric Acid, Vegetable Juice, Sodium Citrate, Carnauba Wax
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Mood lifting supplement Mood Energy Balance
Plant based
Vegan
Glyphosate Residue Free detoxfreeproject.org Gluten free Dairy free Soy free
Formula
Saffron Gotu Kola Passionflower Ginger
FDA Statement of Identity
Superfood Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Take two gummies once daily or as directed by your healthcare practitioner.
Precautions
Medical disclaimer: As with any dietary supplement, consult your healthcare practitioner before using this product, especially if you are pregnant, nursing, anticipate, surgery, take medication on a regular basis or are otherwise under medical supervision.
Not available for resale unless approved by Organifi LLC.
Warning: This product can expose you to chemicals including lead, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
General Statements
Vitamin Angels Proud Supporter This container is made from post consumer recycled materials
Seals/Symbols
Glyphosate Residue Free detoxfreeproject.org
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Storage
Contents may settle. Store in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Happy Drops Sweet Lemon Gummy by Organifi label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Happy Drops Sweet Lemon Gummy by Organifi
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Gummy(ies) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Ginger Root Extract
Interacts with1,007 drugs
Ginger is a widely used culinary spice with a long history in traditional medicine, and it has the strongest evidence for helping with nausea and vomi...
Ginger Root Extract monograph & interactionsGotu Kola Whole Herb Extract
Interacts with579 drugs
Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporti...
Gotu Kola Whole Herb Extract monograph & interactionsPassionflower Aerial Extract
Interacts with836 drugs
Passion flower is a traditional calming herb that many people use for anxiety and sleep. Early studies hint it may help with mild anxiety and restless...
Passionflower Aerial Extract monograph & interactionsSaffr'Activ
Interacts with521 drugs
Saffron is a costly spice that has shown promise in early studies for mild-to-moderate depression and some mood and PMS symptoms, but most research us...
Saffr'Activ monograph & interactionsOther (inactive) ingredients: Cane Sugar, Tapioca Syrup, Water, Pectin, Flavors, Citric Acid, Vegetable Juice, Sodium Citrate, Carnauba Wax. These complete the product’s ingredient list but are not active constituents.
Happy Drops Sweet Lemon Gummy by Organifi Drug Interactions
HelloPharmacist Interaction Report
Organifi's Happy Drops Sweet Lemon Gummy contains four active ingredients, and they interact with a range of medications.
The most serious concern is ginger root extract, which has Moderate-severity interactions with blood thinners (anticoagulants) like warfarin and phenprocoumon — ginger may increase bleeding risk by thinning the blood further. Research in humans is mixed, but case reports document increased bleeding markers when ginger was added to these drugs.
Read the full breakdown — every affected drug type, severity by severity
Ginger also interacts Moderately with blood sugar medications (antidiabetes drugs), blood pressure drugs including the calcium channel blocker nifedipine and the angiotensin II receptor blocker losartan, and certain cancer or specialty medications that are processed through your liver's CYP3A4 pathway or transported by P-glycoprotein. Gotu kola and passion flower both interact Moderately with sedating medications (CNS depressants) — they may add to drowsiness.
Gotu kola also raises theoretical concern about liver toxicity if combined with drugs that harm the liver. Passion flower carries Minor interactions with certain specialty drugs handled by OATP transporters and CYP3A4 enzymes.
Saffron (Saffr'Activ) interacts Moderately with blood pressure medications, blood sugar medications, sedating drugs, and caffeine — saffron may slow how your body clears caffeine.
Altogether, these interactions span 1,340 individual medications. Check your exact prescriptions and over-the-counter medications using the search tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Happy Drops Sweet Lemon Gummy?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Happy Drops Sweet Lemon Gummy interact with 1,361 drugs. Click any drug to see the details.
4 of the 4 ingredients in Happy Drops Sweet Lemon Gummy interact with drugs. Each result below shows which ingredient is responsible. Ginger Root Extract Passionflower Aerial Extract Gotu Kola Whole Herb Extract Saffr'Activ
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Happy Drops Sweet Lemon Gummy — through 1 ingredient. Tap an ingredient for the detail:
Gotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Happy Drops Sweet Lemon Gummy — through 2 ingredients. Tap an ingredient for the detail:
Ginger Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger Root Extract + Ado-trastuzumab Emtansine interactionPassionflower Aerial ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Extract + Ado-trastuzumab Emtansine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Happy Drops Sweet Lemon Gummy — through 1 ingredient. Tap an ingredient for the detail:
Gotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Happy Drops Sweet Lemon Gummy — through 1 ingredient. Tap an ingredient for the detail:
Gotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Happy Drops Sweet Lemon Gummy — through 1 ingredient. Tap an ingredient for the detail:
Ginger Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Ginger Root Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Happy Drops Sweet Lemon Gummy — through 2 ingredients. Tap an ingredient for the detail:
Ginger Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger Root Extract + Abemaciclib interactionPassionflower Aerial ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Happy Drops Sweet Lemon Gummy — through 3 ingredients. Tap an ingredient for the detail:
Ginger Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger Root Extract + Abiraterone interactionGotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Abiraterone interactionPassionflower Aerial ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Happy Drops Sweet Lemon Gummy — through 3 ingredients. Tap an ingredient for the detail:
Gotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Abiraterone Acetate interactionGinger Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger Root Extract + Abiraterone Acetate interactionPassionflower Aerial ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Happy Drops Sweet Lemon Gummy — through 1 ingredient. Tap an ingredient for the detail:
Ginger Root ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Ginger Root Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Happy Drops Sweet Lemon Gummy — through 2 ingredients. Tap an ingredient for the detail:
Ginger Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger Root Extract + Acalabrutinib interactionPassionflower Aerial ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Extract + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Happy Drops Sweet Lemon Gummy — through 3 ingredients. Tap an ingredient for the detail:
Ginger Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Ginger Root Extract + Acarbose interactionSaffr'activAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of saffron with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Saffr'activ + Acarbose interactionGotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Happy Drops Sweet Lemon Gummy — through 2 ingredients. Tap an ingredient for the detail:
Gotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Acebutolol interactionSaffr'activAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of saffron with antihypertensive drugs might have additive effects.
Read the full Saffr'activ + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Happy Drops Sweet Lemon Gummy — through 1 ingredient. Tap an ingredient for the detail:
Ginger Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Ginger Root Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Happy Drops Sweet Lemon Gummy — through 3 ingredients. Tap an ingredient for the detail:
Gotu Kola Whole Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Gotu Kola Whole Herb Extract + Acepromazine interactionSaffr'activCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffr'activ + Acepromazine interactionPassionflower Aerial ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Extract + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Happy Drops Sweet Lemon Gummy — through 2 ingredients. Tap an ingredient for the detail:
Gotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen interactionGinger Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger Root Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Happy Drops Sweet Lemon Gummy — through 2 ingredients. Tap an ingredient for the detail:
Ginger Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger Root Extract + Acetaminophen, Aspirin interactionGotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Happy Drops Sweet Lemon Gummy — through 4 ingredients. Tap an ingredient for the detail:
Gotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen, Aspirin, Caffeine interactionSaffr'activCaffeine Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffr'activ + Acetaminophen, Aspirin, Caffeine interactionGinger Root ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Ginger Root Extract + Acetaminophen, Aspirin, Caffeine interactionPassionflower Aerial ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Happy Drops Sweet Lemon Gummy — through 2 ingredients. Tap an ingredient for the detail:
Gotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionGinger Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger Root Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Happy Drops Sweet Lemon Gummy — through 2 ingredients. Tap an ingredient for the detail:
Gotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen, Butalbital interactionGinger Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger Root Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Happy Drops Sweet Lemon Gummy — through 4 ingredients. Tap an ingredient for the detail:
Ginger Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger Root Extract + Acetaminophen, Butalbital, Caffeine interactionGotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen, Butalbital, Caffeine interactionSaffr'activCaffeine Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffr'activ + Acetaminophen, Butalbital, Caffeine interactionPassionflower Aerial ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Happy Drops Sweet Lemon Gummy — through 4 ingredients. Tap an ingredient for the detail:
Saffr'activCaffeine, Cns Depressants Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffr'activ + Acetaminophen, Butalbital, Caffeine, Codeine interactionPassionflower Aerial ExtractCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionGotu Kola Whole Herb ExtractCns Depressants, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionGinger Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger Root Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Happy Drops Sweet Lemon Gummy — through 4 ingredients. Tap an ingredient for the detail:
Gotu Kola Whole Herb ExtractHepatotoxic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen, Butalbital, Codeine interactionPassionflower Aerial ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Extract + Acetaminophen, Butalbital, Codeine interactionSaffr'activCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffr'activ + Acetaminophen, Butalbital, Codeine interactionGinger Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger Root Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Happy Drops Sweet Lemon Gummy — through 4 ingredients. Tap an ingredient for the detail:
Gotu Kola Whole Herb ExtractCns Depressants, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionSaffr'activCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffr'activ + Acetaminophen, Butalbital, Codeine Phosphate interactionPassionflower Aerial ExtractCns Depressants Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionGinger Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger Root Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Happy Drops Sweet Lemon Gummy — through 4 ingredients. Tap an ingredient for the detail:
Ginger Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger Root Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionPassionflower Aerial ExtractCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Read the full Passionflower Aerial Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionGotu Kola Whole Herb ExtractCns Depressants, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionSaffr'activCaffeine, Cns Depressants Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffr'activ + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Happy Drops Sweet Lemon Gummy — through 4 ingredients. Tap an ingredient for the detail:
Passionflower Aerial ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Extract + Acetaminophen, Caffeine, Codeine interactionGotu Kola Whole Herb ExtractCns Depressants, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen, Caffeine, Codeine interactionSaffr'activCaffeine, Cns Depressants Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffr'activ + Acetaminophen, Caffeine, Codeine interactionGinger Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger Root Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Happy Drops Sweet Lemon Gummy — through 4 ingredients. Tap an ingredient for the detail:
Ginger Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger Root Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionGotu Kola Whole Herb ExtractCns Depressants, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionPassionflower Aerial ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionSaffr'activCns Depressants, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffr'activ + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Happy Drops Sweet Lemon Gummy — through 4 ingredients. Tap an ingredient for the detail:
Gotu Kola Whole Herb ExtractHepatotoxic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionPassionflower Aerial ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionSaffr'activCns Depressants, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Read the full Saffr'activ + Acetaminophen, Caffeine, Dihydrocodeine interactionGinger Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger Root Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Happy Drops Sweet Lemon Gummy — through 4 ingredients. Tap an ingredient for the detail:
Ginger Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger Root Extract + Acetaminophen, Caffeine, Isometheptene interactionSaffr'activCaffeine Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffr'activ + Acetaminophen, Caffeine, Isometheptene interactionGotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen, Caffeine, Isometheptene interactionPassionflower Aerial ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Happy Drops Sweet Lemon Gummy — through 4 ingredients. Tap an ingredient for the detail:
Gotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen, Caffeine, Pyrilamine interactionSaffr'activCaffeine Moderate
Interaction Summary
Theoretically, saffron might inhibit the metabolism of caffeine.
Read the full Saffr'activ + Acetaminophen, Caffeine, Pyrilamine interactionGinger Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger Root Extract + Acetaminophen, Caffeine, Pyrilamine interactionPassionflower Aerial ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Happy Drops Sweet Lemon Gummy — through 3 ingredients. Tap an ingredient for the detail:
Ginger Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger Root Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionGotu Kola Whole Herb ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Gotu Kola Whole Herb Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionPassionflower Aerial ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
Read the full Passionflower Aerial Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Happy Drops Sweet Lemon Gummy with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Ginger Root Extract
Anticoagulant/Antiplatelet Drugs
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs. However, research is conflicting.
Laboratory research suggests that ginger inhibits thromboxane synthetase and decreases platelet aggregation. However, this has not been demonstrated unequivocally in humans, with mixed results from clinical trials. Theoretically, excessive amounts of ginger might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Antidiabetes Drugs
Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Animal and human research suggests that ginger might increase insulin levels and/or decrease blood glucose levels.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Ginger might increase or decrease the levels of CYP3A4 substrates.
In vitro research and some case reports suggest that ginger inhibits CYP3A4 activity. Three case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are CYP3A4 substrates (imatinib, dabrafenib, and crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.
Conversely, other in vitro research suggests that ginger induces CYP3A4 activity, leading to reduced levels of CYP3A4 substrates. However, this interaction has not been reported in humans.
Losartan (Cozaar)
Theoretically, ginger might increase levels of losartan and the risk of hypotension.
In animal research, ginger increased the levels and hypotensive effects of a single dose of losartan. It is not clear if ginger alters the concentration or effects of losartan when taken continuously. Additionally, this interaction has not been shown in humans.
Nifedipine (Procardia)
Ginger may have antiplatelet effects and increase the risk of bleeding if used with nifedipine.
Clinical research shows that combined treatment with ginger 1 gram plus nifedipine 10 mg significantly inhibits platelet aggregation when compared to nifedipine or ginger alone.
P-Glycoprotein Substrates
Ginger might increase the absorption and blood levels of P-glycoprotein (P-gp) substrates.
In vitro research and case reports suggest that ginger inhibits drug efflux by P-gp, potentially increasing absorption and serum levels of P-gp substrates. Two case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are P-gp substrates (trametinib, crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.
Phenprocoumon (Marcoumar, Others)
Ginger might increase the risk of bleeding with phenprocoumon.
Phenprocoumon, a warfarin-related anticoagulant, might increase the international normalized ratio (INR) when taken with ginger. There is one case report of a 76-year-old woman with a stable INR on phenprocoumon that increased to greater than 10 when she began consuming dried ginger and ginger tea.
Warfarin (Coumadin)
Ginger might increase the risk of bleeding with warfarin.
Laboratory research suggests that ginger might inhibit thromboxane synthetase and decrease platelet aggregation. In one case report, ginger increased the INR when taken with phenprocoumon, which has similar pharmacological effects as warfarin. In another case report, ginger increased the INR when taken with a combination of warfarin, hydrochlorothiazide, and acetaminophen. A longitudinal analysis suggests that taking ginger increases the risk of bleeding in patients taking warfarin for at least 4 months. However, research in healthy people suggests that ginger has no effect on INR, or the pharmacokinetics or pharmacodynamics of warfarin. Until more is known, monitor INRs closely in patients taking large amounts of ginger.
Calcium Channel Blockers
Theoretically, taking ginger with calcium channel blockers might increase the risk of hypotension.
Some animal and in vitro research suggests that ginger has hypotensive and calcium channel-blocking effects. Another animal study shows that concomitant administration of ginger and the calcium channel blocker amlodipine leads to greater reductions in blood pressure when compared with amlodipine alone.
Cyclosporine (Neoral, Sandimmune)
Theoretically, when taken prior to cyclosporine, ginger might decrease cyclosporine levels.
In an animal model, ginger juice taken 2 hours prior to cyclosporine administration reduced the maximum concentration and area under the curve of cyclosporine by 51% and 40%, respectively. This effect was not observed when ginger juice and cyclosporine were administered at the same time.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, ginger might increase the levels of CYP1A2 substrates.
In vitro research shows that ginger inhibits CYP1A2 activity. However, this interaction has not been reported in humans.
Cytochrome P450 2B6 (Cyp2B6) Substrates
Theoretically, ginger might increase the levels of CYP2B6 substrates.
In vitro research shows that ginger inhibits CYP2B6 activity. However, this interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, ginger might increase the levels of CYP2C9 substrates.
In vitro research shows that ginger inhibits CYP2C9 activity. However, this interaction has not been reported in humans.
Metronidazole (Flagyl)
Theoretically, ginger might increase levels of metronidazole.
In an animal model, ginger increased the absorption and plasma half-life of metronidazole. In addition, the elimination rate and clearance of metronidazole was significantly reduced.
Passionflower Aerial Extract
Cns Depressants
Concomitant use of passion flower with sedative drugs might cause additive effects and side effects.
Research in animals and humans shows that passion flower has sedative effects which can be additive when used with sedative medications like lorazepam.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, passion flower might decrease the effects of CYP3A4 substrates.
In vitro research suggests that passion flower can induce CYP3A4 enzymes, albeit to a much lower degree than rifampin, a known CYP3A4 inducer.
Organic Anion-Transporting Polypeptide Substrates (Oatp)
Theoretically, passion flower might reduce the bioavailability of OATP2B1 and OATP1A2 substrates.
In vitro research shows that the passion flower constituents apigenin and vitexin inhibit OATP2B1 and OATP1A2. This inhibition may be dose-dependent. One specific high-flavonoid passion flower extract (Valverde) seems to inhibit OATP2B1 and OATP1A2, while another extract with a lower flavonoid concentration (Arkocaps) shows less potent inhibition. OATPs are responsible for the uptake of drugs and other compounds into the body; however, the specific activities of OATP2B1 and OATP1A2 are not well characterized.
Gotu Kola Whole Herb Extract
Cns Depressants
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
In vitro research suggests that gotu kola may have sedative effects via binding of GABA receptors.
Hepatotoxic Drugs
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
There are at least four case reports of hepatotoxicity associated with the use of gotu kola. However, more information is needed to determine if gotu kola was the causative factor in these cases.
Saffr'Activ
Antidiabetes Drugs
Theoretically, concomitant use of saffron with antidiabetes drugs might increase the risk of hypoglycemia.
Some clinical research shows that taking saffron extract reduces fasting levels of glucose when used in addition to hypoglycemic agents. However, saffron powder itself has not been shown to reduce fasting glucose levels.
Antihypertensive Drugs
Theoretically, concomitant use of saffron with antihypertensive drugs might have additive effects.
Animal and human research suggests that saffron extract can decrease blood pressure.
Caffeine
Theoretically, saffron might inhibit the metabolism of caffeine.
A small clinical study suggests that taking saffron powder 300 mg in 150 mL water daily for 5 days and then taking caffeine 200 mg seems to reduce caffeine metabolite levels in the saliva and urine in males, but not females. Theoretically, this may be due to the inhibition of cytochrome P450 1A2 by saffron.
Cns Depressants
Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Clinical research shows that taking saffron extract 60 mg orally daily for 26 weeks can cause drowsiness and sedation. Animal research suggests that adding saffron to hexobarbital further increases sleeping and slows motor activity.
Brand information
Manufacturer and brand details for Happy Drops Sweet Lemon Gummy, from the product label.
Organifi
See all Organifi products- Name
- Organifi LLC.
- City
- San Diego
- State
- CA
- ZipCode
- 92108
- Phone Number
- 760-487-8587
Happy Drops Sweet Lemon Gummy by Organifi: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Happy Drops Sweet Lemon Gummy’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Ginger
Interacts with 1,007 drugsGinger is a widely used culinary spice with a long history in traditional medicine, and it has the strongest evidence for helping with nausea and vomiting, including from motion sickness, pr...
Read the full Ginger monograph → Herb & supplement monographGotu Kola
Interacts with 579 drugsGotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporting herb. Some early studies suggest poss...
Read the full Gotu Kola monograph → Herb & supplement monographPassion Flower
Interacts with 836 drugsPassion flower is a traditional calming herb that many people use for anxiety and sleep. Early studies hint it may help with mild anxiety and restlessness, but the evidence is limited and mo...
Read the full Passion Flower monograph → Herb & supplement monographSaffron
Interacts with 521 drugsSaffron is a costly spice that has shown promise in early studies for mild-to-moderate depression and some mood and PMS symptoms, but most research uses small trials, so results are not defi...
Read the full Saffron monograph →Sources & How We Checked
Happy Drops Sweet Lemon Gummy's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 123 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Ginger 64 references
- Fischer-Rasmussen W, Kjaer SK, Dahl C, Asping U. Ginger treatment of hyperemesis gravidarum. Eur J Obstet Gynecol Reprod Biol 1991;38:19-24. PubMed
- Jewell D, Young G. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev 2000;(2):CD000145. PubMed
- Vutyavanich T, Kraisarin T, Ruangsri R. Ginger for nausea and vomiting in pregnancy: randomized, double-masked, placebo-controlled trial. Obstet Gynecol 2001;97:577-82. DOI
- Backon J. Ginger in preventing nausea and vomiting of pregnancy; a caveat due to its thromboxane synthetase activity and effect on testosterone binding. Eur J Obstet Gynecol Reprod Biol 1991;42:163-4. PubMed
- Srivastava KC. Effect of onion and ginger consumption on platelet thromboxane production in humans. Prostaglandins Leukot Essent Fatty Acids 1989;35:183-5. PubMed
- Stewart JJ, Wood MJ, Wood CD, Mims ME. Effects of ginger on motion sickness susceptibility and gastric function. Pharmacology 1991;42:111-20. PubMed
- Smith C, Crowther C, Willson K, et al. A randomized controlled trial of ginger to treat nausea and vomiting in pregnancy. Obstet Gynecol 2004;103:639-45. PubMed
- Portnoi G, Chng LA, Karimi-Tabesh L, et al. Prospective comparative study of the safety and effectiveness of ginger for the treatment of nausea and vomiting in pregnancy. Am J Obstet Gynecol 2003;189:1374-7.. PubMed
- Wigler I, Grotto I, Caspi D, Yaron M. The effects of Zintona EC (a ginger extract) on symptomatic gonarthritis. Osteoarthritis Cartilage 2003;11:783-9. PubMed
- Ghayur MN, Gilani AH. Ginger lowers blood pressure through blockade of voltage-dependent calcium channels. J Cardiovasc Pharmacol 2005;45:74-80. PubMed
- Thomson M, Al-Qattan KK, Al-Sawan SM, et al. The use of ginger (Zingiber officinale Rosc.) as a potential anti-inflammatory and antithrombotic agent. Prostaglandins Leukot Essent Fatty Acids 2002;67:475-8. PubMed
- Kanerva L, Estlander T, Jolanki R. Occupational allergic contact dermatitis from spices. Contact Dermatitis 1996;35:157-62. PubMed
- Akhani SP, Vishwakarma SL, Goyal RK. Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats. J Pharm Pharmacol 2004;56:101-5.
- Kruth P, Brosi E, Fux R, et al. Ginger-associated overanticoagulation by phenprocoumon. Ann Pharmacother 2004;38:257-60. PubMed
- Jiang X, Williams KM, Liauw WS, et al. Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. Br J Clin Pharmacol 2005;59:425-32. PubMed
- Borrelli F, Capasso R, Aviello G, et al. Effectiveness and safety of ginger in the treatment of pregnancy-induced nausea and vomiting. Obstet Gynecol 2005;105:849-56. PubMed
- Smith C, Crowther C, Wilson K et al. A randomized controlled trial of ginger to treat nausea and vomiting in pregnancy. Obstet Gynecol 2004;103:639-45. PubMed
- Jiang X, Blair EY, McLachlan AJ. Investigation of the effects of herbal medicines on warfarin response in healthy subjects: a population pharmacokinetic-pharmacodynamic modeling approach. J Clin Pharmacol 2006;46:1370-8. PubMed
- Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
- Ozgoli G, Goli M, Moattar F. Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea. J Altern Complement Med 2009;15:129-32. PubMed
- Black CD, Herring MP, Hurley DJ, O'Connor PJ. Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise. J Pain 2010;11:894-903. PubMed
- Heitmann K, Nordeng H, Holst L. Safety of ginger use in pregnancy: results from a large population-based cohort study. Eur J Clin Pharmacol 2012 Jun 17. PubMed
- Ryan JL, Heckler CE, Roscoe JA, et al. Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients. Support Care Cancer. 2012;20:1479-89. PubMed
- Backon J. Ginger as an antiemetic: possible side effects due to its thromboxane synthetase activity. Anaesthesia. 1991;46(8):705-6.. PubMed
- Abebe W. Herbal medication: potential for adverse interactions with analgesic drugs. J Clin Pharm Ther. 2002;27:391-401. PubMed
- Argento A, Tiraferri E, Marzaloni M. [Oral anticoagulants and medicinal plants. An emerging interaction]. Ann Ital Med Int. 2000;15:139-43.
- Young HY, Liao JC, Chang YS, et al. Synergistic effect of ginger and nifedipine on human platelet aggregation: a study in hypertensive patients and normal volunteers. Am J Chin Med. 2006;34:545-51. PubMed
- Greenway FL, Liu Z, Martin CK, et al. Safety and efficacy of NT, an herbal supplement, in treating human obesity. Int J Obes (Lond). 2006;30:1737-41. PubMed
- Shalansky S, Lynd L, Richardson K, et al. Risk of warfarin-related bleeding events and supratherapeutic international normalized ratios associated with complementary and alternative medicine: a longitudinal analysis. Pharmacotherapy. 2007;27:1237-47. PubMed
- Lesho EP, Saullo L, Udvari-Nagy S. A 76-year-old woman with erratic anticoagulation. Cleve Clin J Med. 2004;71:651-6. PubMed
- Okonta JM, Uboh M, Obonga WO. Herb-Drug Interaction: A Case Study of Effect of Ginger on the Pharmacokinetic of Metronidazole in Rabbit. Indian Journal of Pharmaceutical Sciences (India) 2008;70(230):232. PubMed
- Chiang HM, Chao PD, Hsiu SL, et al. Ginger significantly decreased the oral bioavailability of cyclosporine in rats. Am J Chin Med. 2006;34:845-55. PubMed
- Bhandari U, Kanojia R, Pillai KK. Effect of ethanolic extract of Zingiber officinale on dyslipidaemia in diabetic rats. J Ethnopharmacol. 2005;97:227-30. PubMed
- Ojewole JA. Analgesic, antiinflammatory and hypoglycaemic effects of ethanol extract of Zingiber officinale (Roscoe) rhizomes (Zingiberaceae) in mice and rats. Phytother Res. 2006;20:764-72.
- Al-Amin ZM, Thomson M, Al-Qattan KK, et al. Anti-diabetic and hypolipidaemic properties of ginger (Zingiber officinale) in streptozotocin-induced diabetic rats. Br J Nutr. 2006;96:660-6.
- Islam MS, Choi H. Comparative effects of dietary ginger (Zingiber officinale) and garlic (Allium sativum) investigated in a type 2 diabetes model of rats. J Med Food. 2008;11:152-9.
- Cady RK, Goldstein J, Nett R, et al. A double-blind placebo-controlled pilot study of sublingual feverfew and ginger (LipiGesic M) in the treatment of migraine. Headache 2011;51:1078-86.
- Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
- Sripramote, M. and Lekhyananda, N. A randomized comparison of ginger and vitamin B6 in the treatment of nausea and vomiting of pregnancy. J Med Assoc.Thai. 2003;86(9):846-853.
- Lohsiriwat, S., Rukkiat, M., Chaikomin, R., and Leelakusolvong, S. Effect of ginger on lower esophageal sphincter pressure. J.Med.Assoc.Thai. 2010;93(3):366-372.
- Liu, P. H. and Ho, H. L. Ginger and drug bezoar induced small bowel obstruction. J R.Coll.Surg.Edinb. 1983;28(6):397-398.
- Maghbooli M, Golipour F, Moghimi Esfandabadi A, Yousefi M. Comparison between the efficacy of ginger and sumatriptan in the ablative treatment of the common migraine. Phytother Res 2014;28(3):412-5. PubMed
- Mahluji S, Attari VE, Mobasseri M, Payahoo L, Ostadrahimi A, Golzari SE. Effects of ginger (Zingiber officinale) on plasma glucose level, HbA1c and insulin sensitivity in type 2 diabetic patients. Int J Food Sci Nutr 2013;64(6):682-6.
- Mozaffari-Khosravi H, Talaei B, Jalali BA, Najarzadeh A, Mozayan MR. The effect of ginger powder supplementation on insulin resistance and glycemic indices in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial. Complement PubMed
- Paramdeep G. Efficacy and tolerability of ginger (Zingiber officinale) in patients of osteoarthritis of knee. Indian J Physiol Pharmacol 2013;57(2):177-83.
- Rahnama P, Montazeri A, Huseini HF, Kianbakht S, Naseri M. Effect of Zingiber officinale R. rhizomes (ginger) on pain relief in primary dysmenorrhea: a placebo randomized trial. BMC Complement Altern Med 2012;12:92. PubMed
- Viljoen E, Visser J, Koen N, Musekiwa A. A systematic review and meta-analysis of the effect and safety of ginger in the treatment of pregnancy-associated nausea and vomiting. Nutr J 2014;13:20. PubMed
- Bartels EM, Folmer VN, Bliddal H, et al. Efficacy and safety of ginger in osteoarthritis patients: a meta-analysis of randomized placebo-controlled trials. Osteoarthritis Cartilage. 2015;23(1):13-21. PubMed
- Choi JS, Han JY, Ahn HK, et al. Assessment of fetal and neonatal outcomes in the offspring of women who had been treated with dried ginger (Zingiberis rhizoma siccus) for a variety of illnesses during pregnancy. J Obstet Gynaecol. 2015;35(2):125-30.
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