Havoc Ingredients & Drug Interactions
by RPN Recomp Performance Nutrition
What is this page for?
First and foremost: checking Havoc against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Havoc is a dietary supplement by RPN Recomp Performance Nutrition with 1 active ingredient. Its ingredients are commonly taken for building muscle mass, increasing strength, cutting or losing body fat.Based on those ingredients, 370 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are 2a, 3a-Epithio-17a-Methyl-5a-Androstan-17b-Ol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Havoc by RPN Recomp Performance Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with Havoc by RPN Recomp Performance Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Havoc by RPN Recomp Performance Nutrition
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Epistane.
- The most serious interaction on file is rated Moderate.
- For scale: 371 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Havoc, straight from the product label.
| Brand | RPN Recomp Performance Nutrition |
|---|---|
| Net contents | 90 Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | Dec 22, 2019 |
| DSLD ID | 210034 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Havoc by RPN Recomp Performance Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| 2a, 3a-Epithio-17a-Methyl-5a-Androstan-17b-Ol | 10 mg | -- |
Other ingredients: Gelatin Capsule, Microcrystalline Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
The peak of performance!
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Take 2-3 capsules daily as directed by a physician. Do not exceed 3 capsules per day, do not exceed 4 weeks usage per 4 month period.
Precautions
Do not exceed 3 capsules per day, do not exceed 4 weeks usage per 4 month period.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Havoc by RPN Recomp Performance Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Havoc by RPN Recomp Performance Nutrition
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
2a, 3a-Epithio-17a-Methyl-5a-Androstan-17b-Ol
Interacts with370 drugs
Epistane is a synthetic anabolic steroid (a methylated 'designer steroid'), not a true dietary supplement or herb, even though it has been sold as a '...
2a, 3a-Epithio-17a-Methyl-5a-Androstan-17b-Ol monograph & interactionsOther (inactive) ingredients: Gelatin Capsule, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.
Havoc by RPN Recomp Performance Nutrition Drug Interactions
Havoc contains a single active ingredient, and it has known interactions with 370 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Havoc?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Havoc interact with 370 drugs. Click any drug to see the details.
1 of the 1 ingredient in Havoc interact with drugs. Each result below shows which ingredient is responsible. 2a, 3a-Epithio-17a-Methyl-5a-Androstan-17b-Ol
Teclistamab-cqyvTecvayli
How Teclistamab-cqyv interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Teclistamab-cqyv interactionTenofovir Alafenamide FumarateVemlidy
How Tenofovir Alafenamide Fumarate interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Tenofovir Alafenamide Fumarate interactionTenofovir, Emtricitabine, EfavirenzAtripla
How Tenofovir, Emtricitabine, Efavirenz interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Tenofovir, Emtricitabine, Efavirenz interactionTeplizumab-mzwvTzield
How Teplizumab-mzwv interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Teplizumab-mzwv interactionTerbinafineLamisil
How Terbinafine interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Terbinafine interactionTeriflunomideAubagio
How Teriflunomide interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Teriflunomide interactionTestosteroneAndrogel, Andropatch, Delatestryl, Intrinsa, Natesto, Nebido +3 more
How Testosterone interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Testosterone interactionTestosterone EnanthateXyosted
How Testosterone Enanthate interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Testosterone Enanthate interactionTestosterone UndecanoateAndriol, Aveed, Jatenzo, Kyzatrex
How Testosterone Undecanoate interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Testosterone Undecanoate interactionTetracyclineAchromycin, Achromycin V, Nor-Tet, Robitet, Sumycin, Sumycin 250 +6 more
How Tetracycline interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Tetracycline interactionTizanidineOntralfy, Zanaflex
How Tizanidine interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Tizanidine interactionTocilizumabActemra
How Tocilizumab interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Tocilizumab interactionTolcaponeTasmar
How Tolcapone interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Tolcapone interactionToripalimab-tpziLoqtorzi
How Toripalimab-tpzi interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Toripalimab-tpzi interactionTrabectedinYondelis
How Trabectedin interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Trabectedin interactionTramadol, AcetaminophenTramacet
How Tramadol, Acetaminophen interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Tramadol, Acetaminophen interactionTrandolapril, VerapamilTarka
How Trandolapril, Verapamil interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Trandolapril, Verapamil interactionTrazodoneDesyrel, Oleptro
How Trazodone interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Trazodone interactionTrazodone HclTrazorel
How Trazodone Hcl interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Trazodone Hcl interactionTroglitazoneRezulin
How Troglitazone interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Troglitazone interactionTrovafloxacinTrovan, Trovan Injection
How Trovafloxacin interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Trovafloxacin interactionTucatinibTukysa
How Tucatinib interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Tucatinib interactionUmbralisib TosylateUkoniq
How Umbralisib Tosylate interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Umbralisib Tosylate interactionVadadustatVafseo
How Vadadustat interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Vadadustat interactionValproic AcidDepacon, Depakene, Valproate
How Valproic Acid interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Valproic Acid interactionVanzacaftor, Tezacaftor, DeutivacaftorAlyftrek
How Vanzacaftor, Tezacaftor, Deutivacaftor interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Vanzacaftor, Tezacaftor, Deutivacaftor interactionVedolizumabEntyvio
How Vedolizumab interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Vedolizumab interactionVerapamilCalan, Calan SR, Covera HS, Isoptin, Isoptin SR, Veramil +3 more
How Verapamil interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Verapamil interactionVonoprazan, AmoxicillinVoquezna Dual
How Vonoprazan, Amoxicillin interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Vonoprazan, Amoxicillin interactionVonoprazan, Amoxicillin, ClarithromycinVoquezna Triple
How Vonoprazan, Amoxicillin, Clarithromycin interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Vonoprazan, Amoxicillin, Clarithromycin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Havoc with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
2a, 3a-Epithio-17a-Methyl-5a-Androstan-17b-Ol
Hepatotoxic Drugs
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Epistane is an anabolic androgenic steroid, and more specifically a 17-alpha-alkylated androgen. Therefore, there is concern that epistane has hepatotoxic effects. Also, epistane is structurally similar to epitiostanol, which has been associated with hepatotixicity in a case series of four patients.
Brand information
Manufacturer and brand details for Havoc, from the product label.
RPN Recomp Performance Nutrition
See all RPN Recomp Performance Nutrition products- Name
- Recomp Performance Nutrition (RPN)
Havoc by RPN Recomp Performance Nutrition: Common Questions
Does Havoc by RPN Recomp Performance Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Havoc is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Havoc’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Havoc's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Epistane 3 references
- Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed
- Rahnema CD, Crosnoe LE, Kim ED. Designer steroids - over-the-counter supplements and their androgenic component: review of an increasing problem. Andrology. 2015;3(2):150-5. PubMed
- Díaz FC, Sáez-González E, Benlloch S, et al. Albumin dialysis with MARS for the treatment of anabolic steroid-induced cholestasis. Ann Hepatol. 2016;15(6):939-943.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC